Balram Rathish, Arun Wilson, Anup Warrier, Roshni Pillay, Joe ThomasIndian Journal of Pathology and Microbiology 2020 63(3):488-490 Aspergillus meningitis is a rare clinical entity that is much more frequently observed among immunocompetent patients. Here we present the case of a 28 year old immunocompetent lady with Aspergillus fumigatus meningitis possibly following spinal anaesthesia for her caesarean section. The diagnosis of Aspergillus meningitis is very difficult and challenging. Even...
Fri Aug 07, 2020 00:00
Smita Mary Matthai, Suceena Alexander, Shibu Jacob, Neelaveni Duhli, Vinoi George David, Santosh VarugheseIndian Journal of Pathology and Microbiology 2020 63(3):463-466 The renal diseases commonly associated with myeloma include primary amyloidosis, cast nephropathy, and light chain deposition disease. Less frequent forms of renal involvement encountered in the course of myeloma are crystalline and non-crystalline proximal tubulopathies, neoplastic plasma cell infiltration, and immunoglobulin...
Fri Aug 07, 2020 00:00
Ranjan AgrawalIndian Journal of Pathology and Microbiology 2020 63(3):347-349
Fri Aug 07, 2020 00:00
Sandeep Rai, Saroj Singh, Ritu GuptaIndian Journal of Pathology and Microbiology 2020 63(3):505-506
Fri Aug 07, 2020 00:00
Vatsala Misra, Ranjan Agrawal, Harendra Kumar, Asaranti Kar, Usha Kini, Aruna Poojary, Indranil Chakrabarti, Sharada Rai, Anika Singhal, S Vijay Shankar, Jayaram N IyengarIndian Journal of Pathology and Microbiology 2020 63(3):350-357 Declared as a pandemic by WHO on March 11, 2020, COVID-19 has brought about a dramatic change in the working of different laboratories across the country. Diagnostic laboratories testing different types of samples play a vital role in the treatment management. Irrespective...
Fri Aug 07, 2020 00:00
Ilke O Kazaz, Ahmet S Teoman, Sevdegul MunganIndian Journal of Pathology and Microbiology 2020 63(3):475-477 Primary mesotheliomas of the tunica vaginalis testis are very rare malignant tumors. They are generally associated with exposure to asbestos. They may manifest as hydrocele, testis tumor, inguinal hernia, or epididymitis. After differential diagnosis, treatment is primarily surgical. Adjuvant therapeutic methods for mesotheliomas of the tunica vaginalis testis, with their high mortality,...
Fri Aug 07, 2020 00:00
Amanjit Bal, Ranjan Agrawal, Pradeep Vaideeswar, Sudheer Arava, Amita JainIndian Journal of Pathology and Microbiology 2020 63(3):358-366 The entire world is under a devastating pandemic caused by COVID-19 with a high mortality rate. Knowledge of the viral structure, factors that help in its progression and spread, pathological findings, diagnostic methods and, treatment modalities helps in understanding the viral disease and also in treating the patients in a better way besides preventing the...
Fri Aug 07, 2020 00:00
Urothelial carcinoma of the renal pelvis with synchronous ipsilateral papillary renal cell carcinoma
Neha Bagga, Sudeep Khera, Gautam R Choudhary, Rajat K TutejaIndian Journal of Pathology and Microbiology 2020 63(3):497-498
Fri Aug 07, 2020 00:00
Anita M BorgesIndian Journal of Pathology and Microbiology 2020 63(3):367-368
Fri Aug 07, 2020 00:00
Ranjan AgrawalIndian Journal of Pathology and Microbiology 2020 63(3):345-346
Fri Aug 07, 2020 00:00
Nazanin Mahdavi, Pouyan Aminishakib, Parisa Nabiyi, Alireza Ghanadan, Maedeh Ghorbanpour, Merva Soluk-TekkesinIndian Journal of Pathology and Microbiology 2020 63(3):369-375 Background: Oral verrucous carcinoma is a low-grade subtype of oral squamous cell carcinoma that should be differentiated from oral verrucous hyperplasia, a premalignant lesion. Stromal activated myofibroblasts known as cancer-associated fibroblasts have an active role in the initiation and progression of the cancers via...
Fri Aug 07, 2020 00:00
Sandhya Bordiya, Kumari Priyanka, Dharmendra GargIndian Journal of Pathology and Microbiology 2020 63(3):470-471 We report a case of testicular granulosa cell tumor of adult type in a 65-year-old male patient who has presented with hepatic metastasis. Although, this type of sex cord stromal tumor is relatively common in the ovaries, it is extremely unusual in the testis, and it probably represents the rarest type of testicular sex cord stromal tumor.
Fri Aug 07, 2020 00:00
Pranoti Vitthalrao Lengare, Siddhi Gaurish Sinai Khandeparkar, Avinash R Joshi, Bageshri P Gogate, Smita Ganeshrao Solanke, Sujit Hanumant GoreIndian Journal of Pathology and Microbiology 2020 63(3):376-381 Introduction: Breast cancer (BC) is the most common cancer and leading cause of death in women. Aim: This study was conducted to study the cyclin D1 expression in BC and its correlation with other clinicopathological parameters such as tumor size, histological grade, lymph node status, estrogen...
Fri Aug 07, 2020 00:00
Ayeesha Shaik, Sreeja T Thekkelakayil, Vijay Kumawat, Anurag Gupta, Manu GoyalIndian Journal of Pathology and Microbiology 2020 63(3):481-484 HbQ variants are rare alpha globin chain variants commonly found in Sindhi community. It results from a point mutation of α-1 globin gene at position 223 of the coding region of exon 64. It is inherited in an autosomal dominant fashion. HbQ-India is usually clinically silent in heterozygous state unless associated with other conditions like beta thalassemia,...
Fri Aug 07, 2020 00:00
Apexa P Raval, Urja N Desai, Jigna S Joshi, Franky D ShahIndian Journal of Pathology and Microbiology 2020 63(3):382-387 Background and Aims: Epithelial stromal interaction protein-1 (EPSTI-1) is originally identified as stromal-fibroblast – induced gene in breast cancer. It was found to be involved in promotion of EMT, breast cancer invasion, metastasis and anchorage-independent growth in vitro. Strong expression was observed in various tissues as well as higher expression was observed in invasive...
Fri Aug 07, 2020 00:00
Pavithra Ayyanar, Suvradeep Mitra, Suvendu PurkaitIndian Journal of Pathology and Microbiology 2020 63(3):493-494 Solid cell nest (SCN) of thyroid is a benign histomorphological mimicker of papillary microcarcinoma. Previous studies have elucidated a few immunohistochemical markers of SCN that aid in its distinction from papillary microcarcinoma. The positivity of GATA3 in SCN has been demonstrated only recently. We also document GATA3 positivity in three cases of SCN.
Fri Aug 07, 2020 00:00
Harshima D Wijesinghe, Janakie Fernando, Upul Senarath, Gayani K Wijesinghe, Menaka D S. LokuhettyIndian Journal of Pathology and Microbiology 2020 63(3):388-396 Background: Triple negative breast carcinoma (TNBC) and basal-like breast carcinoma (BLBC) are subtypes of breast carcinoma (BCa) that are associated with poor survival. Aims: To study the prevalence, clinicopathological profile and survival of TNBC among a Sri Lankan patient cohort and to determine the proportion and predictive histological...
Fri Aug 07, 2020 00:00
Kriti Chauhan, Varun HatwalIndian Journal of Pathology and Microbiology 2020 63(3):500-502
Fri Aug 07, 2020 00:00
Keya Basu, Subhrajyoti Karmakar, Moumita Sengupta, Arpita Roychowdhury, Alakendu Ghosh, Manimoy BandopadhyayIndian Journal of Pathology and Microbiology 2020 63(3):397-404 Context: Systemic lupus erythematosus is an autoimmune multisystem disease with a high predilection for renal involvement. Lupus nephritis develops in 20% to 75% within the first two years. Presentation varies from subnephrotic proteinuria to end-stage renal disease. Aims: To study clinical features, biochemical, and serological...
Fri Aug 07, 2020 00:00
Sujata S Giriyan, Purushotham Reddy, Mithraa D SekarIndian Journal of Pathology and Microbiology 2020 63(3):509-510
Fri Aug 07, 2020 00:00
Nehal S Abouhashem, Eman H Abdelbary, Mohamed M H. Abdalla, Mohamed El-ShazlyIndian Journal of Pathology and Microbiology 2020 63(3):405-411 Objective: Renal oncocytoma (RO) and chromophobe renal cell carcinoma (ChRCC) originate from the same cell origin, that is, the intercalated cells of the collecting duct.[1] In most cases, there are clear morphologic differences between RO and ChRCC; however, in some instances, overlapping features may be encountered and the differentiation between the two...
Fri Aug 07, 2020 00:00
Nishant Sagar, Prerna Arora, Nita Khurana, PN AgarwalIndian Journal of Pathology and Microbiology 2020 63(3):460-462 Mesenchymal neoplasm is rare in renal pelvic region. Aggressive angiomyxomas are the neoplasms seen predominantly in female genital region. These tumors are locally aggressive with rare cases presenting with metastasis. Its occurrence in renal pelvis is extremely rare with only five cases reported in the literature. The present case is the sixth case reported in a 15-year-old girl...
Fri Aug 07, 2020 00:00
Hulya Tosun Yildirim, Dondu Nergiz, Canan Sadullahoglu, Zelal Akgunduz, Senay Yildirim, Selen Dogan, Cem SezerIndian Journal of Pathology and Microbiology 2020 63(3):412-417 Background: Cyclin D1, a member of the cyclin protein family, is instrumental in the cell cycle due to its influence on the progression from G1 to the S phase. Its overexpression causes reduced doubling time and is also associated with clonogenic growth. The purpose of the present study was to assess cyclin D1 expression...
Fri Aug 07, 2020 00:00
Nishant Sagar, Shramana Mandal, Nita Khurana, Ashok KumarIndian Journal of Pathology and Microbiology 2020 63(3):467-469 Genital rhabdomyomas are extremely rare benign tumors of skeletal muscle origin, majority of them being reported in vaginal location. Extensive literature search revealed only three such cases reported in cervix. We hereby report fourth such case of cervical rhabdomyoma in a 35-years-old female patient. The diagnosis was confirmed by histomorphology with desmin and myoD1 positivity...
Fri Aug 07, 2020 00:00
Serkan Y Celik, Özgür İlhan ÇelikIndian Journal of Pathology and Microbiology 2020 63(3):418-422 Background: Endometrioid-type endometrial carcinoma is the most common malignancy of the female genital tract in developed countries. The prognosis greatly depends on the grade and stage of the disease. Aims: In some patients, the disease recurs in a short time after the surgical/medical therapy. Hence, it is important to predict the patients who will have worse prognosis at the beginning, to choose...
Fri Aug 07, 2020 00:00
Sujata S Giriyan, MB Bharati, Nahida Afshan ShigliIndian Journal of Pathology and Microbiology 2020 63(3):472-474 Gonadoblastomas are unusual gonadal neoplasias that frequently appear in dysgenetic gonads. Approximately 80% of patients are phenotypic females and 20% are males. A very high frequency is associated with malignant germ cell tumor. We present a case of 37-year-old normal fertile man with descended testis who presented with swelling and pain in left testis since 6 months. On examination,...
Fri Aug 07, 2020 00:00
Maria S Koleva, Dorian I Dikov, Veselin T Belovezhdov, Victoria SarafianIndian Journal of Pathology and Microbiology 2020 63(3):423-426 Background: To investigate prostatic eosinophilic metaplasia (EM) in a large series of cases and their relationship with the basic prostate pathology in TURP-material: benign prostatic hyperplasia (BPH), National Institutes of Health category IV prostatitis (also called histologic prostatitis or HP), and prostatic adenocarcinoma (PCa). Aim: The relation between...
Fri Aug 07, 2020 00:00
Zeynep Sagnak Yilmaz, Safak ErsozIndian Journal of Pathology and Microbiology 2020 63(3):478-480 A granular cell tumor (GCT) is a rare, usually benign soft tissue neoplasm that is commonly seen in the head and neck region. It is derived from the Schwann cells of the peripheral nerves. GCT is uncommon in children. 6-year-old girl was referred to our hospital for swelling over her left scapula, and a surgical excision was performed to remove the mass. Microscopically, the tumor was composed of...
Fri Aug 07, 2020 00:00
Bharat Rekhi, Srushti Karmarkar, Chhavi Gupta, Kedar K Deodhar, Santosh Menon, Saleem Pathuthara, Amita Maheshwari, TS Shylasree, Sudeep GuptaIndian Journal of Pathology and Microbiology 2020 63(3):427-434 One of the common indications of ascitic fluid examination in gynecological oncopathology is the detection and classification of malignant cells, especially in cases of clinically suspicious tubo-ovarian masses. The present study was undertaken to assess and validate the diagnostic utility...
Fri Aug 07, 2020 00:00
Keyu Liu, Huijuan Song, Jie Shi, Weijun Zhang, Rui Mu, Li LiIndian Journal of Pathology and Microbiology 2020 63(3):485-487 Myeloma plasma cells vary from mature forms to immature, plasmablastic, and pleomorphic cells. Only a few cases of morphologic variant of plasma cell neoplasm have been reported, in which the plasma cell neoplasm presented with lymphoplasmacytic, megakaryocytic, plasmablastic, lymphocytosis-like, and variant hairy cell leukemia-like morphological features. A 66-year-old...
Fri Aug 07, 2020 00:00
Kavita Gaur, Vandana Puri, Shailaja Shukla, Sunita Sharma, Santosh Suman, Renu SinghIndian Journal of Pathology and Microbiology 2020 63(3):435-440 Aims: (a) To evaluate the types and frequencies of preanalytical errors occurring in a tertiary care hematology diagnostic center and (b) To evaluate differences if any, across groups [outpatient data (OPD) vs inpatient data (IPD), type of test requested [complete blood count (CBC) vs coagulation] and laboratory (routine vs emergency). Settings and...
Fri Aug 07, 2020 00:00
Monika Gupta, Nitika Grover, Rajeev SenIndian Journal of Pathology and Microbiology 2020 63(3):491-492
Fri Aug 07, 2020 00:00
Vikender S Yadav, Prasenjit Das, Renu Yadav, Nitesh TewariIndian Journal of Pathology and Microbiology 2020 63(3):441-444 Oral inflammatory myofibroblastic tumor (IMT) is extremely rare and its manifestation as generalized gingival enlargement (GGE) has never been reported. We are reporting the case of 50-year-old female patient presenting with recurrent GGE for 4 years. Panoramic radiograph revealed severe bone loss in posterior sextants and root resorption in some teeth. Initial incisional...
Fri Aug 07, 2020 00:00
Ravi H Phulware, Sudheer Arava, P Rajashekar, Milind P Hote, Sarvesh P Singh, Sandeep Seth, Ruma RayIndian Journal of Pathology and Microbiology 2020 63(3):495-496
Fri Aug 07, 2020 00:00
Gayathri Priyadharshini, Manjiri Phansalkar, Dilip Phansalkar, Vellore Seetharam HariIndian Journal of Pathology and Microbiology 2020 63(3):445-448 An ossified variant of meningioma in the intracranial region is very rare. We report a case of a 28-year-old female who presented with headache for 4 years. Imaging revealed an extra-axial calcified mass in the left parieto-occipital lobe. The differential diagnosis included osteoblastoma both intracranial and periosteal, calcifying pseudotumor of...
Fri Aug 07, 2020 00:00
Varughese P George, Kathirvelu Shanmugasamy, Sowmya Srinivasan, Anandraj V Krishnamurthy, A T. M Venkat RaghavanIndian Journal of Pathology and Microbiology 2020 63(3):499-500
Fri Aug 07, 2020 00:00
Serdar Ugras, Markku MiettinenIndian Journal of Pathology and Microbiology 2020 63(3):449-452 This is a description of a dedifferentiated liposarcoma seen in a 27-year-old female patient. The tumor originated from the vallecula and contains distinctive bodies. These bodies, which are formed by the aggregation of tumor cells, contain collagen in several regions and are oval or elongated in shape. Immunohistochemically, the tumor cells showed staining for MDM2, p16, Vimentin, beta catenin, smooth...
Fri Aug 07, 2020 00:00
Sonali Susmita Nayak, Sangeetha K Parthiban, Peter Paul, Sumeet GujralIndian Journal of Pathology and Microbiology 2020 63(3):503-505
Fri Aug 07, 2020 00:00
Sarojini Raman, Nilanjan Mukherjee, Kanakalata Dash, Kamal K SenIndian Journal of Pathology and Microbiology 2020 63(3):453-455 Opportunistic infections affecting central nervous system (CNS) have high prevalence in developing countries and cryptococcosis is one of them. It is associated with myriad of signs symptoms and clinical behavior. Though commonly associated with AIDS/HIV infection, it has been reported to be pathogenic in immunocompetent patients. Leptomeningitis is most common presentation...
Fri Aug 07, 2020 00:00
Sanjay A Pai, Reinhold Paul LinkeIndian Journal of Pathology and Microbiology 2020 63(3):506-508
Fri Aug 07, 2020 00:00
Chaithra G Venkataramana, Saraswathy Sreeram, PV Santosh Rai, GG Laxman Prabhu, KN Sanman, Shrinath P ShettyIndian Journal of Pathology and Microbiology 2020 63(3):456-459 An elderly adult woman presented with upper abdominal pain to the urology department. Imaging studies revealed a right adrenal lesion with central necrosis, abutting the large vessels and suggestive of malignancy. Histopathology showed an encapsulated spindle cell tumor with marked nuclear atypia, cystic change, and hemorrhage....
Fri Aug 07, 2020 00:00
Bharat RekhiIndian Journal of Pathology and Microbiology 2020 63(3):511-512
Fri Aug 07, 2020 00:00
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