Related Articles Is Elective Cancer Surgery Safe During the COVID-19 Pandemic? World J Surg. 2020 Aug 06;: Authors: Ji C, Singh K, Luther AZ, Agrawal A Abstract BACKGROUND: The COVID-19 pandemic has resulted in a significant decrease in the number of elective cancer operations performed. Cancer patients are felt to be a high-risk group for COVID-19, and therefore, concerns have been raised regarding the safety of operating during this time;...
Sun Aug 09, 2020 15:48
Related Articles Author's Reply: Aerosol Box, an Operating Room Security Measure in COVID-19 Pandemic. World J Surg. 2020 Aug 06;: Authors: Leyva-Moraga FA, Leyva-Moraga E, Leyva-Moraga F, Juanz-González A, Ibarra-Celaya JM, Ocejo-Gallegos JA, Barreras-Espinoza JA PMID: 32766956 [PubMed - as supplied by publisher]
Sun Aug 09, 2020 15:48
Related Articles The Efficacy of Neoadjuvant Versus Adjuvant Therapy for Resectable Esophageal Cancer Patients: A Systematic Review and Meta-Analysis. World J Surg. 2020 Aug 05;: Authors: Xiao X, Hong HG, Zeng X, Yang YS, Luan SY, Li Y, Chen LQ, Yuan Y Abstract OBJECTIVE: Inconclusive results are available as to whether chemo/radiotherapy should be administered to resectable esophageal cancer patients before surgery (neoadjuvant therapy) or...
Sat Aug 08, 2020 15:54
Related Articles Diffuse large B cell lymphoma of the central nervous system presenting with intratumoral hemorrhage: a case report and literature review. World Neurosurg. 2020 Aug 04;: Authors: Bureta C, Higa N, Makino R, Takajo T, Yonezawa H, Uchida H, Yoshimoto K PMID: 32763371 [PubMed - as supplied by publisher]
Sun Aug 09, 2020 14:34
Related Articles Brain radionecrosis after adjuvant radiation therapy for a primary intracerebral undifferentiated sarcoma. World Neurosurg. 2020 Aug 04;: Authors: Napolitano M, Ranieri A, Maniscalco GT, Riccardi F, De Dominicis G, Caiazzo P PMID: 32763370 [PubMed - as supplied by publisher]
Sun Aug 09, 2020 14:34
Related Articles Atlanto-occipital dissociation in the setting of relatively normal radiological findings: A case report. World Neurosurg. 2020 Aug 04;: Authors: Souslian FG, Patel PD, Elsherif MA Abstract BACKGROUND: Craniocervical junction (CCJ) dislocations are often fatal. Atlanto-occipital dissociation (AOD) can be challenging to diagnose, especially among patients who present with absent or subtle radiological signs. CLINICAL...
Sun Aug 09, 2020 14:34
Related Articles Red flag for cauda equina syndrome in symptomatic lumbar disc herniation. World Neurosurg. 2020 Aug 03;: Authors: Grasso G, Munakomi S, Sallì M PMID: 32758658 [PubMed - as supplied by publisher]
Sat Aug 08, 2020 14:34
Related Articles Stereotactic Radiosurgery for Atypical and Anaplastic Meningiomas. World Neurosurg. 2020 Aug 03;: Authors: Helis CA, Hughes RT, Cramer CK, Tatter SB, Laxton AW, Bourland JD, Munley MT, Chan MD Abstract BACKGROUND: While most meningiomas are benign, a small proportion have atypical or anaplastic histology, and exhibit more aggressive behavior. Treatment of these tumors is controversial, particularly for patients who recur after...
Sat Aug 08, 2020 14:34
Related Articles Immunohistochemical Profiles of Matrix Metalloproteinases and Vascular Endothelial Growth Factor Overexpression in the Antoni B area of Vestibular Schwannomas. World Neurosurg. 2020 Aug 03;: Authors: Wen M, Yang S, Wang C, Yu E, Zhang H, Zhang Y, Ruan L, Shi L, Ni J, Luo J, Cao Z, Xia L Abstract OBJECTIVE: To evaluate the clinical manifestations of cystic vestibular schwannomas (VSs), investigate the immunohistochemical profiles...
Sat Aug 08, 2020 14:34
Related Articles Surveillance Venous Duplex Ultrasound in the Neurosurgical Population: A Single-Center Quality Improvement Initiative. World Neurosurg. 2020 Aug 03;: Authors: Rozman PA, Kurland DB, Golub D, Trang M, Rothstein A, Lewis A, Pacione D Abstract BACKGROUND: Venous thromboembolism (VTE) represents a significant source of morbidity and mortality in the inpatient population and is considered a leading preventable cause of death among...
Sat Aug 08, 2020 14:34
Related Articles Pedicle screw insertion: Is O-arm based navigation superior to the conventional free-hand technique? A systematic review and meta-analysis. World Neurosurg. 2020 Aug 03;: Authors: Sun J, Wu D, Wang Q, Wei Y, Yuan F Abstract BACKGROUND: Though O-arm based navigation (ON) has been considered a better choice than the conventional free-hand technique for spine surgery, clinical evidence demonstrating the accuracy of O-arm based...
Sat Aug 08, 2020 14:34
Related Articles "Gas Embolism after Hydrogen Peroxide Use during Spine Surgery: A Case Report and Literature Review". World Neurosurg. 2020 Aug 03;: Authors: Zhao SL, Zhang XY, Xiao Y, Mo XY, Chen ZP, Lin W, Huang ZF, Chen BL Abstract BACKGROUND: As an irrigant, an antiseptic and a hemostatic agent, hydrogen peroxide (H2O2) is widely used in surgical treatment, but it has been surrounded by persistent controversy. Fatal or near-fatal embolic...
Sat Aug 08, 2020 14:34
Related Articles Robot-assisted Percutaneous Pedicle Screw Placement: Evaluation of Accuracy of the First 100 Screws and Comparison to Cohort of Fluoroscopy-guided Screws. World Neurosurg. 2020 Aug 03;: Authors: Fayed I, Tai A, Triano M, Sayah A, Makariou E, Voyadzis JM, Sandhu FA Abstract OBJECTIVE: Percutaneous pedicle screws (PPS) are used to stabilize the spine after interbody fusion in minimally invasive approaches. Recently, robotic assistance...
Sat Aug 08, 2020 14:34
Related Articles Optimizing Radiosurgery for Trigeminal Neuralgia: Impact of Radiation Dose and Anatomic Target on Patient Outcomes. World Neurosurg. 2020 Aug 03;: Authors: Wilson TA, Karlsson B, Huang L, Ramanathan D, Oyoyo U, Boling W Abstract OBJECTIVES: Radiosurgery is an increasingly popular treatment for trigeminal neuralgia (TN); however, several treatment variables require further study. This meta-analysis was conducted to clarify ambiguity...
Sat Aug 08, 2020 14:34
Tuberculum Sellae Meningiomas inPregnancy: 3 Cases Treated in the 2nd Trimester & Literature Review.
Related Articles Tuberculum Sellae Meningiomas inPregnancy: 3 Cases Treated in the 2nd Trimester & Literature Review. World Neurosurg. 2020 Aug 03;: Authors: Mallari RJ, Thakur JD, Griffiths C, Krauss H, Eisenberg A, Barkhoudarian G, Kelly DF Abstract BACKGROUND: Tuberculum sella meningiomas typically present with progressive visual loss. It is also known that meningiomas can become symptomatic during pregnancy. Herein we report on 3 patients...
Sat Aug 08, 2020 14:34
Related Articles Creating a Comprehensive Research Platform for Surgical Technique and Operative Outcome in Primary Brain Tumor Neurosurgery. World Neurosurg. 2020 Aug 03;: Authors: Winkler-Schwartz A, Yilmaz R, Tran DH, Gueziri HE, Ying B, Tuznik M, Fonov V, Collins L, Rudko DA, Li J, Debergue P, Pazos V, Del Maestro R Abstract BACKGROUND: The operative environment poses many challenges to studying the relationship between surgical acts and...
Sat Aug 08, 2020 14:34
Related Articles Prevalence and Outcomes of Medium Vessel Occlusions With Discrepant Infarct Patterns. Stroke. 2020 Aug 06;:STROKEAHA120030041 Authors: Ospel JM, Cimflova P, Marko M, Mayank A, Hafeez M, Almekhlafi MA, Hill MD, Demchuk AM, Menon BK, Goyal M Abstract BACKGROUND AND PURPOSE: The prognosis of medium vessel occlusions (MeVOs), that is, M2/3 middle cerebral artery, A2/3 anterior cerebral artery, and P2/3 posterior cerebral artery...
Sat Aug 08, 2020 17:37
Related Articles Curcumin, a Multifaceted Hormetic Agent, Mediates an Intricate Crosstalk between Mitochondrial Turnover, Autophagy, and Apoptosis. Oxid Med Cell Longev. 2020;2020:3656419 Authors: Rainey NE, Moustapha A, Petit PX Abstract Curcumin has extensive therapeutic potential because of its antioxidant, anti-inflammatory, and antiproliferative properties. Multiple preclinical studies in vitro and in vivo have proven curcumin to be...
Sun Aug 09, 2020 13:20
Effects of matrine on the proliferation and apoptosis of vincristine-resistant retinoblastoma cells.
Related Articles Effects of matrine on the proliferation and apoptosis of vincristine-resistant retinoblastoma cells. Exp Ther Med. 2020 Sep;20(3):2838-2844 Authors: Zhao B, Li B, Liu Q, Gao F, Zhang Z, Bai H, Wang Y Abstract Matrine is an active component of Leguminosae plants and is thought to exhibit anti-tumor effects. However, the effects of matrine on drug-resistant cancer have not been fully elucidated. The present study aimed to...
Sun Aug 09, 2020 13:20
Related Articles Corrigendum: Shikonin Inhibits Cancer Through P21 Upregulation and Apoptosis Induction. Front Pharmacol. 2020;11:1088 Authors: Wang F, Mayca Pozo F, Tian D, Geng X, Yao X, Zhang Y, Tang J Abstract [This corrects the article DOI: 10.3389/fphar.2020.00861.]. PMID: 32765281 [PubMed - as supplied by publisher]
Sun Aug 09, 2020 13:20
Related Articles JNK and Autophagy Independently Contributed to Cytotoxicity of Arsenite combined With Tetrandrine via Modulating Cell Cycle Progression in Human Breast Cancer Cells. Front Pharmacol. 2020;11:1087 Authors: Yu B, Yuan B, Li J, Kiyomi A, Kikuchi H, Hayashi H, Hu X, Okazaki M, Sugiura M, Hirano T, Fan Y, Pei X, Takagi N Abstract Novel therapeutic strategies for breast cancer are urgently needed due to the sustained development...
Sun Aug 09, 2020 13:20
Related Articles Exosomal miR-638 Inhibits Hepatocellular Carcinoma Progression by Targeting SP1. Onco Targets Ther. 2020;13:6709-6720 Authors: Yang J, Li B, Zhao S, Du H, Du Y Abstract Purpose: Exosomal microRNAs (miRNAs) play essential roles in the development of hepatocellular carcinoma (HCC). Nevertheless, the role and mechanism of exosomal miR-638 in HCC development remain largely unknown. Methods: Exosomes were isolated...
Sun Aug 09, 2020 13:20
Related Articles miR-188-5p Promotes Tumor Growth by Targeting CD2AP Through PI3K/AKT/mTOR Signaling in Children with Acute Promyelocytic Leukemia. Onco Targets Ther. 2020;13:6681-6697 Authors: Wang D, Chen J, Ding Y, Kong H, You H, Zhao Y, Wei H, Liu Y Abstract Purpose: Pediatric acute promyelocytic leukemia (APL) accounts for 10% of pediatric acute myelogenous leukemia (AML) case and is accompanied by a tendency to hemorrhage. miR-188-5p...
Sun Aug 09, 2020 13:20
Related Articles Folate and Pegylated Aliphatic Polyester Nanoparticles for Targeted Anticancer Drug Delivery. Int J Nanomedicine. 2020;15:4899-4918 Authors: Tsolou A, Angelou E, Didaskalou S, Bikiaris D, Avgoustakis K, Agianian B, Koffa MD Abstract Purpose: The use of chemotherapeutic agents to combat cancer is accompanied by high toxicity due to their inability to discriminate between cancer and normal cells. Therefore, cancer therapy...
Sun Aug 09, 2020 13:20
Related Articles Anti-Breast Cancer Effect of 2-Dodecyl-6-Methoxycyclohexa-2,5-Diene-1,4-Dione in vivo and in vitro Through MAPK Signaling Pathway. Drug Des Devel Ther. 2020;14:2667-2684 Authors: Zhou X, Wu X, Qin L, Lu S, Zhang H, Wei J, Chen L, Jiang L, Wu Y, Chen C, Huang R Abstract Background: 2-Dodecyl-6-methoxycyclohexa-2,5-diene-1,4-dione (DMDD) has been reported to inhibit a variety of cancer cell lines. The purpose of this study...
Sun Aug 09, 2020 13:20
Related Articles Anti-Cancer Effect of 3-Hydroxy-β-Ionone Identified from Moringa oleifera Lam. Leaf on Human Squamous Cell Carcinoma 15 Cell Line. Molecules. 2020 Aug 05;25(16): Authors: Luetragoon T, Pankla Sranujit R, Noysang C, Thongsri Y, Potup P, Suphrom N, Nuengchamnong N, Usuwanthim K Abstract Squamous cell carcinoma is the most common type of head and neck cancer worldwide. Radiation and chemotherapy are general treatments for...
Sun Aug 09, 2020 13:20
Related Articles Discovery of Novel Agents on Spindle Assembly Checkpoint to Sensitize Vinorelbine-Induced Mitotic Cell Death Against Human Non-Small Cell Lung Cancers. Int J Mol Sci. 2020 Aug 05;21(16): Authors: Chang YC, Tseng YL, Leu WJ, Du CM, Jiang YH, Hsu LC, Hsu JL, Hou DR, Guh JH Abstract Non-small cell lung cancer (NSCLC) accounts about 80% of all lung cancers. More than two-thirds of NSCLC patients have inoperable, locally advanced...
Sun Aug 09, 2020 13:20
Related Articles Identification of osalmid metabolic profile and active metabolites with anti-tumor activity in human hepatocellular carcinoma cells. Biomed Pharmacother. 2020 Aug 04;130:110556 Authors: Wu Z, Zhan Y, Wang L, Tong J, Zhang L, Lin M, Jin X, Jiang L, Lou Y, Qiu Y Abstract BACKGROUNDS: Ribonucleotide reductase (RR) catalyzes the essential step in the formation of all four deoxynucleotides. Upregulated activity of RR plays an...
Sun Aug 09, 2020 13:20
Related Articles Silver nanoparticle-activated COX2/PGE2 axis involves alteration of lung cellular senescence in vitro and in vivo. Ecotoxicol Environ Saf. 2020 Aug 04;204:111070 Authors: Chen B, Chai Q, Xu S, Li Q, Wu T, Chen S, Wu L Abstract Silver nanoparticles (AgNPs) are widely used as antimicrobial agents and resulted in their accumulation in environment. The purpose of this study was to investigate the detailed molecular mechanisms...
Sun Aug 09, 2020 13:20
Related Articles Design, synthesis and molecular modeling of phenyl dihydropyridazinone derivatives as B-Raf inhibitors with anticancer activity. Bioorg Chem. 2020 Jul 28;103:104148 Authors: Thabit MG, Mostafa AS, Selim KB, Elsayed MAA, Nasr MNA Abstract Three new series of phenyl dihydropyridazinone derivatives 4b-8i have been designed, synthesized and evaluated for their anticancer activity against different cancer cell lines. Nine compounds...
Sun Aug 09, 2020 13:20
Related Articles In silico pharmacological prediction and cytotoxicity of flavonoids glycosides identified by UPLC-DAD-ESI-MS/MS in extracts of Humulus lupulus leaves cultivated in Brazil. Nat Prod Res. 2020 Aug 07;:1-6 Authors: da Silva RG, Almeida TC, Reis ACC, Filho SAV, Brandão GC, da Silva GN, de Sousa HC, de Almeida VL, Lopes JCD, de Souza GHB Abstract Ethanolic (EB) extract and hexanic (SH) and hydromethanolic (SEM) sub-extracts...
Sun Aug 09, 2020 13:20
Related Articles Gentiopicroside Inhibits Cell Growth and Migration on Cervical Cancer via the Reciprocal MAPK/Akt Signaling Pathways. Nutr Cancer. 2020 Aug 07;:1-12 Authors: Hu Z, Wang H, Fu Y, Ma K, Ma X, Wang J Abstract Cervical cancer (CC) is a common gynecological malignancy and represents a major global health challenge. Chemotherapeutic agents are commonly applied in treatment of CC, while along various adverse effects and chemotherapy...
Sun Aug 09, 2020 13:20
Related Articles C1orf109L binding DHX9 promotes DNA damage depended on the R-loop accumulation and enhances camptothecin chemosensitivity. Cell Prolif. 2020 Aug 06;:e12875 Authors: Dou P, Li Y, Sun H, Xie W, Zhang X, Zhang X, Zhang D, Qiao S, Ci Y, Nie H, Han F, Li Y Abstract OBJECTIVES: R-loop is a three-stranded nucleic acid structure of RNA/DNA hybrid, which occurs naturally during transcription, and more R-loop accumulation can trigger...
Sat Aug 08, 2020 13:46
Related Articles Pds5A and Pds5B Display Non-redundant Functions in Mitosis and Their Loss Triggers Chk1 Activation. Front Cell Dev Biol. 2020;8:531 Authors: Al-Jomah N, Mukololo L, Anjum A, Al Madadha M, Patel R Abstract Background: Pds5 is an abundant HEAT-repeat-containing protein that binds to cohesin and mediates sister chromatid cohesion. In vertebrates, Pds5A and Pds5B are known to protect DNA replication fork, as their loss leads...
Sat Aug 08, 2020 13:46
Related Articles Involvement of Bcl-2 Activation and G1 Cell Cycle Arrest in Colon Cancer Cells Induced by Titanium Dioxide Nanoparticles Synthesized by Microwave-Assisted Hybrid Approach. Front Bioeng Biotechnol. 2020;8:606 Authors: Ranjan S, Dasgupta N, Mishra D, Ramalingam C Abstract The toxic effect of TiO2 nanoparticles (TNP) greatly varies with the variation in synthesis protocol followed. Any morphological alteration of TNPs affects...
Sat Aug 08, 2020 13:46
Related Articles Bidirect effects from cisplatin combine with rosmarinic acid (RA) or hot water extracts of Glechoma hederacea (HWG) on renal cancer cells. Chin Med. 2020;15:77 Authors: Chou ST, Ho BY, Tai YT, Huang CJ, Chao WW Abstract Background: Cisplatin (CDDP) is a chemotherapeutic drug which also causes adverse side effects. Glechoma hederacea is a traditional Chinese herb belonging to the Labiatae family and has many biological activities....
Sat Aug 08, 2020 13:46
Related Articles LncRNA IGFBP4-1 promotes tumor development by activating Janus kinase-signal transducer and activator of transcription pathway in bladder urothelial carcinoma. Int J Biol Sci. 2020;16(13):2271-2282 Authors: Li C, Cao Y, Zhang L, Li J, Wu H, Ling F, Zheng J, Wang J, Li B, He J, Xie X, Li Z, Chen Y, He X, Guo M, Wei H, Ye J, Guo Y, Zhang S, Liu L, Liu G, Liu C Abstract Insulin-like growth factor binding protein 4-1 (IGFBP4-1),...
Sat Aug 08, 2020 13:46
Related Articles A New Inhibitor of Tubulin Polymerization Kills Multiple Cancer Cell Types and Reveals p21-Mediated Mechanism Determining Cell Death after Mitotic Catastrophe. Cancers (Basel). 2020 Aug 04;12(8): Authors: Zdioruk M, Want A, Mietelska-Porowska A, Laskowska-Kaszub K, Wojsiat J, Klejman A, Użarowska E, Koza P, Olejniczak S, Pikul S, Konopka W, Golab J, Wojda U Abstract Induction of mitotic catastrophe through the disruption...
Sat Aug 08, 2020 13:46
Related Articles Loss of Sbds in zebrafish leads to neutropenia and pancreas and liver atrophy. JCI Insight. 2020 Aug 06;: Authors: Oyarbide U, Shah AN, Amaya-Mejia W, Snyderman M, Kell M, Allende D, Calo E, Topczewski J, Corey S Abstract Shwachman-Diamond syndrome (SDS) is characterized by exocrine pancreatic insufficiency, neutropenia, and skeletal abnormalities. Biallelic mutations in SBDS, which encodes a ribosome maturation factor,...
Sat Aug 08, 2020 13:46
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