Related Articles miR-204/COX5A axis contributes to invasion and chemotherapy resistance in estrogen receptor-positive breast cancers. Cancer Lett. 2020 Aug 03;: Authors: Zeng J, Li G, Xia Y, Wang F, Wang Y, Xu S, Zhou Y, Liu X, Xie X, Zhang J Abstract Breast cancer is the most common cancer among women worldwide, with 70% being estrogen receptor-positive (ER+). Although ER-targeted treatment is effective in treating ER + breast cancer,...
Sat Aug 08, 2020 13:46
Related Articles Haimufang decoction, a Chinese medicine formula for lung cancer, arrests cell cycle, stimulates apoptosis in NCI-H1975 cells, and induces M1 polarization in RAW 264.7 macrophage cells. BMC Complement Med Ther. 2020 Aug 05;20(1):243 Authors: Ma WP, Hu SM, Xu YL, Li HH, Ma XQ, Wei BH, Li FY, Guan HS, Yu GL, Liu M, Liu HB Abstract BACKGROUND: Lung cancer has the highest morbidity and mortality in the world and novel treatment...
Sat Aug 08, 2020 13:46
Related Articles Phytochemical Profile, and Antiproliferative and Proapoptotic Effects of Pouteria ramiflora (Mart.) Radlk. Leaf Extract, and Its Synergism with Cisplatin in HepG2 Cells. J Med Food. 2020 Aug 04;: Authors: Tuttis K, da Costa DLMG, Serpeloni JM, Dos Santos LC, Varanda EA, Vilegas W, Martínez-López W, Cólus IMS Abstract Different species of the genus Pouteria have been used in folk medicine for the treatment of inflammation,...
Sat Aug 08, 2020 13:46
Related Articles Cell growth dilutes the cell cycle inhibitor Rb to trigger cell division. Science. 2020 07 24;369(6502):466-471 Authors: Zatulovskiy E, Zhang S, Berenson DF, Topacio BR, Skotheim JM Abstract Cell size is fundamental to cell physiology. For example, cell size determines the spatial scale of organelles and intracellular transport and thereby affects biosynthesis. Although some genes that affect mammalian cell size have been identified,...
Sat Aug 08, 2020 13:46
Related Articles Repurposing of quinoline alkaloids identifies their ability to induce sub G0/G1 phase cell cycle arrest and enhance doxorubicin-induced apoptosis in cervical and hepatocellular carcinoma cells. Biotechnol Appl Biochem. 2020 Aug 05;: Authors: El-Mesery M, Seher A, El-Shafey M, El-Dosoky M, Badria FA Abstract The ability of quinoline alkaloids (cinchonine, cinchonidine, quinine and quinidine) to sensitize different human...
Fri Aug 07, 2020 13:31
Related Articles Design, synthesis, and cytotoxicity screening of new synthesized imidazolidine-2-thiones as VEGFR-2 enzyme inhibitors. Arch Pharm (Weinheim). 2020 Aug 05;:e2000121 Authors: Zaki I, Ramadan HMM, El-Sayed EH, Abd El-Moneim M Abstract A series of imidazolin-2-thione derivatives was synthesized and structurally confirmed through the use of different spectroscopic techniques such as infrared, nuclear magnetic resonance, and...
Fri Aug 07, 2020 13:31
Related Articles A Switch in p53 Dynamics Marks Cells That Escape from DSB-Induced Cell Cycle Arrest. Cell Rep. 2020 Aug 04;32(5):107995 Authors: Tsabar M, Mock CS, Venkatachalam V, Reyes J, Karhohs KW, Oliver TG, Regev A, Jambhekar A, Lahav G Abstract Cellular responses to stimuli can evolve over time, resulting in distinct early and late phases in response to a single signal. DNA damage induces a complex response that is largely orchestrated...
Fri Aug 07, 2020 13:31
Related Articles The Ubiquitin Ligase TRIP12 Limits PARP1 Trapping and Constrains PARP Inhibitor Efficiency. Cell Rep. 2020 Aug 04;32(5):107985 Authors: Gatti M, Imhof R, Huang Q, Baudis M, Altmeyer M Abstract PARP inhibitors (PARPi) cause synthetic lethality in BRCA-deficient tumors. Whether specific vulnerabilities to PARPi exist beyond BRCA mutations and related defects in homology-directed repair (HDR) is not well understood. Here,...
Fri Aug 07, 2020 13:31
Related Articles Down-regulation of TFAM increases the sensitivity of tumour cells to radiation via p53/TIGAR signalling pathway. J Cell Mol Med. 2019 07;23(7):4545-4558 Authors: Jiang X, Wang J Abstract Mitochondrial transcription factor A (TFAM) is a key regulator of mitochondria biogenesis. Previous studies confirmed that reduced TFAM expression sensitized tumours cells to chemical therapy reagents and ionizing irradiation (IR). However,...
Fri Aug 07, 2020 13:31
Related Articles Efficacy and safety of sodium valproate plus lamotrigine in children with refractory epilepsy. Exp Ther Med. 2020 Sep;20(3):2698-2704 Authors: Zhang D, Qiu L, Zhang Y, Sang Y, Zheng N, Liu X Abstract Efficacy and safety of sodium valproate (SV) and lamotrigine (LTG) in treating refractory epilepsy (RE) in children and the predictive value of serum neuron-specific enolase (NSE) and central nervous system specific S100β protein...
Sun Aug 09, 2020 15:44
Related Articles Evaluation of Fear in Idiopathic Epilepsy Using Population-Based Survey and Bhalla-Gharagozli Fear in Epilepsy Questionnaire (BG-FEQ). Neuropsychiatr Dis Treat. 2020;16:1685-1693 Authors: Gharagozli K, Lotfalinezhad E, Amini F, Saii V, Bhalla D Abstract Introduction: The primary objective of this study was to evaluate fear related to epilepsy and its treatment among those with idiopathic epilepsy. Our secondary objective was...
Sun Aug 09, 2020 15:44
Related Articles EEG source estimation in a rare patient with cold-induced reflex epilepsy. Epileptic Disord. 2020 Aug 07;: Authors: Ren Y, Li X, Cong F, Xiao S, Zhang Q, Ao T, Zhang J, Wang Y, Ristaniemi T, Zhang R Abstract Temperature-related reflex epilepsy most often takes the form of hot water epilepsy, but very rarely, reflex epilepsy is related to cold temperature. We report a 70-year-old male who had seizures triggered by cold sensations...
Sun Aug 09, 2020 15:44
Related Articles Paraclinical serum markers as aids in the diagnosis of autoimmune encephalitis. J Neuroimmunol. 2020 Jul 17;347:577324 Authors: Culler G, Bachman E, VanHaerents S Abstract Expert opinion suggests the presence ANA and thyroid antibodies may be helpful to diagnosis autoimmune encephalitis (AE). This study investigates the sensitivity of these serum markers in a cohort of 26 patients with AE. TPO-Ab, TG-Ab and ANA (titer ≥1:320)...
Sun Aug 09, 2020 15:44
Related Articles Mental Health Nurses' Knowledge of Clozapine. Issues Ment Health Nurs. 2020 Aug 07;:1-8 Authors: Sanjeevi S, Cocoman A Abstract Clozapine, sold under the brand name Clozaril, is an antipsychotic medication prescribed since the 1970s as an effective treatment for individuals with treatment resistive schizophrenia. Medical experts have produced extensive literature on the need for close monitoring as this medication can cause...
Sun Aug 09, 2020 15:44
Sleep Architecture in Valproate-Induced Nocturnal Enuresis in Primary School and Preschool Children.
Related Articles Sleep Architecture in Valproate-Induced Nocturnal Enuresis in Primary School and Preschool Children. J Child Neurol. 2020 Aug 07;:883073820944051 Authors: Esmael A, Elsherief M, Abdelsalam M, Bendary L, Egila H Abstract Nocturnal enuresis is one of the side effects of valproic acid treatment, and generally underdiagnosed by clinicians. Studies reported that a variable incidence of valproic acid-induced nocturnal enuresis is...
Sun Aug 09, 2020 15:44
Related Articles Perampanel Increases Cortical EEG Fast Activity in Child and Adult Patients Affected by Epilepsy: A Quantitative EEG Study. Clin EEG Neurosci. 2020 Aug 07;:1550059420947936 Authors: Liguori C, Spanetta M, Izzi F, Russo A, Guerra A, Mercuri NB, Placidi F Abstract OBJECTIVE: Quantitative EEG (qEEG) is an established technique used as objective measure for evaluating the effect of antiseizure medications (ASMs) on EEG background...
Sun Aug 09, 2020 15:44
21 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: epilepsy treatment These pubmed results were generated on 2020/08/08PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sat Aug 08, 2020 15:44
Related Articles Antiseizure drug efficacy and tolerability in established and novel drug discovery seizure models in outbred vs inbred mice. Epilepsia. 2020 Aug 05;: Authors: Koneval Z, Knox KM, Memon A, Zierath DK, White HS, Barker-Haliski M Abstract OBJECTIVE: Initial identification of new investigational drugs for the treatment of epilepsy is commonly conducted in well-established mouse acute and chronic seizure models: for example, maximal...
Fri Aug 07, 2020 13:23
Related Articles Predictors of remission in patients with epilepsy. Neurol Neurochir Pol. 2020 Aug 05;: Authors: Wężyk K, Słowik A, Bosak M Abstract AIM OF STUDY: To evaluate the rate and factors predicting seizure remission in a large cohort of patients with epilepsy. MATERIALS AND METHODS: Patients with epilepsy treated at a university epilepsy clinic were included in this study. The following information was collected by means of...
Fri Aug 07, 2020 13:23
Related Articles [Inpatient treatment costs, cost-driving factors and potential reimbursement problems due to epileptic seizure-related injuries and fractures]. Chirurg. 2020 Aug 05;: Authors: Verboket RD, Mühlenfeld N, Sterz J, Störmann P, Marzi I, Balcik Y, Rosenow F, Strzelczyk A, Willems LM Abstract BACKGROUND: The systematic analysis of disease-specific costs is becoming increasingly more relevant in an economically oriented healthcare...
Fri Aug 07, 2020 13:23
Related Articles Obstructive Sleep Apnea. Continuum (Minneap Minn). 2020 Aug;26(4):908-928 Authors: Kirsch DB Abstract PURPOSE OF REVIEW: Obstructive sleep apnea (OSA) is often overlooked by clinicians; however, undiagnosed OSA can lead to negative outcomes for patients, including patients with underlying neurologic conditions. Clinicians should be aware of what questions to ask, what diagnostic tests to use, and what treatments to consider...
Fri Aug 07, 2020 13:23
Related Articles Epilepsy by the numbers - From the US Centers for Disease Control and Prevention: Six in 10 adults with active epilepsy saw a neurologist or epilepsy specialist in the past year, United States, 2017. Epilepsy Behav. 2020 Aug 01;112:107348 Authors: Kobau R, Sapkota S, Pennell PB, Croft JB Abstract This study used the most recent national data on epilepsy from the 2017 National Health Interview Survey (NHIS) to examine the distribution...
Fri Aug 07, 2020 13:23
Related Articles Interaction of morphine tolerance with pentylenetetrazole-induced seizure threshold in mice: The role of NMDA-receptor/NO pathway. Epilepsy Behav. 2020 Aug 02;112:107343 Authors: Zamanian G, Shayan M, Rahimi N, Bahremand T, Shafaroodi H, Ejtemaei-Mehr S, Aghaei I, Dehpour AR Abstract N-methyl-d-aspartate receptor (NMDA-R)/nitric oxide (NO) pathway is involved in the intensification of the analgesic effect of opioids and the...
Fri Aug 07, 2020 13:23
Related Articles The emerging role of PARP inhibitors in prostate cancer. Expert Rev Anticancer Ther. 2020 Aug 06;:1-12 Authors: Stellato M, Guadalupi V, Sepe P, Mennitto A, Claps M, Zattarin E, Verzoni E, Valdagni R, De Braud FG, Santini D, Tonini G, Procopio G Abstract INTRODUCTION: In prostate cancer , there has recently been an emerging interest in mutations in genes belonging to the homologous recombination repair (HRR) pathway and in the...
Sat Aug 08, 2020 13:24
Related Articles Cholangiocarcinoma: investigations into pathway-targeted therapies. Expert Rev Anticancer Ther. 2020 Aug 06;: Authors: Ntanasis-Stathopoulos I, Tsilimigras DI, Gavriatopoulou M, Schizas D, Pawlik TM Abstract INTRODUCTION: Cholangiocarcinoma refers to malignant disease of the biliary tract and accounts for 3% of all gastrointestinal tumors. Surgical intervention is currently the only potentially curative strategy for cholangiocarcinoma....
Sat Aug 08, 2020 13:24
Related Articles Combination therapy in advanced urothelial cancer: the role of PARP, HER-2 and mTOR inhibitors. Expert Rev Anticancer Ther. 2020 Aug 06;: Authors: Mollica V, Maggio I, Lopez-Beltran A, Montironi R, Cimadamore A, Cheng L, Rizzo A, Giunchi F, Schiavina R, Fiorentino M, Brunocilla E, Massari F Abstract INTRODUCTION: Despite significant advances in the treatment of metastatic urothelial carcinoma, including the advent of immune...
Sat Aug 08, 2020 13:24
Related Articles Lung cancer management: monitoring and treating resistance development in third generation EGFR TKIs. Expert Rev Anticancer Ther. 2020 Aug 05;: Authors: Franceschini D, Rossi S, Loi M, Chiola I, Piccoli F, Lutman FR, Finocchiaro G, Toschi L, Santoro A, Scorsetti M Abstract INTRODUCTION: Patients treated with third generation EGFR TKIs will develop resistance to treatment at a certain point. Early detection of resistance occurrence...
Fri Aug 07, 2020 13:20
Related Articles Decoding Hearing-Related Changes in Older Adults' Spatiotemporal Neural Processing of Speech Using Machine Learning. Front Neurosci. 2020;14:748 Authors: Mahmud MS, Ahmed F, Al-Fahad R, Moinuddin KA, Yeasin M, Alain C, Bidelman GM Abstract Speech perception in noisy environments depends on complex interactions between sensory and cognitive systems. In older adults, such interactions may be affected, especially in those individuals...
Sun Aug 09, 2020 13:29
Related Articles Measuring Neural Arousal for Advertisements and Its Relationship With Advertising Success. Front Neurosci. 2020;14:736 Authors: Eijlers E, Boksem MAS, Smidts A Abstract Abundant research has established the important role of ad-evoked feelings on consumers' reaction to advertising. However, measurement of feelings through explicit self-report is not without its limitations. The current study adds to previous work by showing...
Sun Aug 09, 2020 13:29
Related Articles NOSA, an Analytical Toolbox for Multicellular Optical Electrophysiology. Front Neurosci. 2020;14:712 Authors: Oltmanns S, Abben FS, Ender A, Aimon S, Kovacs R, Sigrist SJ, Storace DA, Geiger JRP, Raccuglia D Abstract Understanding how neural networks generate activity patterns and communicate with each other requires monitoring the electrical activity from many neurons simultaneously. Perfectly suited tools for addressing this...
Sun Aug 09, 2020 13:29
Related Articles Optimal Multichannel Artifact Prediction and Removal for Neural Stimulation and Brain Machine Interfaces. Front Neurosci. 2020;14:709 Authors: Sadeghi Najafabadi M, Chen L, Dutta K, Norris A, Feng B, Schnupp JWH, Rosskothen-Kuhl N, Read HL, Escabí MA Abstract Neural implants that deliver multi-site electrical stimulation to the nervous systems are no longer the last resort but routine treatment options for various neurological...
Sun Aug 09, 2020 13:29
Related Articles Aberrant Cerebellar Circuitry in the Spinocerebellar Ataxias. Front Neurosci. 2020;14:707 Authors: Robinson KJ, Watchon M, Laird AS Abstract The spinocerebellar ataxias (SCAs) are a heterogeneous group of neurodegenerative diseases that share convergent disease features. A common symptom of these diseases is development of ataxia, involving impaired balance and motor coordination, usually stemming from cerebellar dysfunction...
Sun Aug 09, 2020 13:29
Related Articles Transcutaneous Auricular Vagus Nerve Stimulation at 20 Hz Improves Depression-Like Behaviors and Down-Regulates the Hyperactivity of HPA Axis in Chronic Unpredictable Mild Stress Model Rats. Front Neurosci. 2020;14:680 Authors: Li S, Wang Y, Gao G, Guo X, Zhang Y, Zhang Z, Wang Y, Zhang J, Wang J, Li L, Yang Y, Rong P Abstract Transcutaneous auricular vagus nerve stimulation (taVNS) has gained growing interest as a non-invasive...
Sun Aug 09, 2020 13:29
Related Articles Progress in LRRK2-Associated Parkinson's Disease Animal Models. Front Neurosci. 2020;14:674 Authors: Seegobin SP, Heaton GR, Liang D, Choi I, Blanca Ramirez M, Tang B, Yue Z Abstract Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene are the most frequent cause of familial Parkinson's disease (PD). Several genetic manipulations of the LRRK2 gene have been developed in animal models such as rodents, Drosophila, Caenorhabditis...
Sun Aug 09, 2020 13:29
Related Articles Neurofeedback for Pain Management: A Systematic Review. Front Neurosci. 2020;14:671 Authors: Roy R, de la Vega R, Jensen MP, Miró J Abstract Background: Chronic pain is a significant global health issue. For most individuals with chronic pain, biomedical treatments do not provide adequate relief. Given the evidence that neurophysiological abnormalities are associated with pain, it is reasonable to consider treatments that target...
Sun Aug 09, 2020 13:29
Related Articles Extramuscular Recording of Spontaneous EMG Activity and Transcranial Electrical Elicited Motor Potentials in Horses: Characteristics of Different Subcutaneous and Surface Electrode Types and Practical Guidelines. Front Neurosci. 2020;14:652 Authors: Journée SL, Journée HL, Reed SM, Berends HI, de Bruijn CM, Delesalle CJG Abstract Introduction: Adhesive surface electrodes are worthwhile to explore in detail as alternative to...
Sun Aug 09, 2020 13:29
Related Articles The Role of Serotonin in Singultus: A Review. Front Neurosci. 2020;14:629 Authors: Petroianu GA, Lorke DE Abstract The use of dopamine receptor blockers for chronic singultus treatment is based-at least partially-on circular thinking: chlorpromazine is FDA-approved for hiccups, chlorpromazine is a neuroleptic, neuroleptics are dopamine receptor blockers, and therefore hiccup is due to dopaminergic dysfunction. Chlorpromazine...
Sun Aug 09, 2020 13:29
Related Articles Corrigendum: The Pathophysiology of Degenerative Cervical Myelopathy and the Physiology of Recovery Following Decompression. Front Neurosci. 2020;14:628 Authors: Akter F, Yu X, Qin X, Yao S, Nikrouz P, Syed YA, Kotter M Abstract [This corrects the article DOI: 10.3389/fnins.2020.00138.]. PMID: 32765205 [PubMed - as supplied by publisher]
Sun Aug 09, 2020 13:29
Related Articles The Zebrafish Amygdaloid Complex - Functional Ground Plan, Molecular Delineation, and Everted Topology. Front Neurosci. 2020;14:608 Authors: Porter BA, Mueller T Abstract In mammals and other tetrapods, a multinuclear forebrain structure, called the amygdala, forms the neuroregulatory core essential for emotion, cognition, and social behavior. Currently, higher circuits of affective behavior in anamniote non-tetrapod vertebrates...
Sun Aug 09, 2020 13:29
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