Related Articles Mechanisms Contributing to the Generation of Mayer Waves. Front Neurosci. 2020;14:395 Authors: Ghali MGZ, Ghali GZ Abstract Mayer waves may synchronize overlapping propriobulbar interneuronal microcircuits constituting the respiratory rhythm and pattern generator, sympathetic oscillators, and cardiac vagal preganglionic neurons. Initially described by Sir Sigmund Mayer in the year 1876 in the arterial pressure waveform of anesthetized...
Sun Aug 09, 2020 13:29
Related Articles A Radiomics Approach to Predicting Parkinson's Disease by Incorporating Whole-Brain Functional Activity and Gray Matter Structure. Front Neurosci. 2020;14:751 Authors: Cao X, Wang X, Xue C, Zhang S, Huang Q, Liu W Abstract Parkinson's disease (PD) is a progressive, chronic, and neurodegenerative disorder that is primarily diagnosed by clinical examinations and magnetic resonance imaging (MRI). In this study, we proposed a machine...
Sat Aug 08, 2020 13:31
Related Articles Vitamin B12 Supplementation and NT-proBNP Levels in COPD Patients: A Secondary Analysis of a Randomized and Controlled Study in Rehabilitation. Front Neurosci. 2020;14:740 Authors: Paulin FV, Goelzer LS, Müller PT Abstract Purpose: There is evidence of complex interaction between vitamin B12 (vB12) level, hyperhomocysteinemia (HyCy), and natriuretic peptide secretion. Exercise training could also modulate such interaction. In...
Sat Aug 08, 2020 13:31
Related Articles Abnormalities in Brain and Muscle Microstructure and Neurochemistry of the DMD Rat Measured by in vivo Diffusion Tensor Imaging and High Resolution Localized 1H MRS. Front Neurosci. 2020;14:739 Authors: Xu S, Tang S, Li X, Iyer SR, Lovering RM Abstract Duchenne muscular dystrophy (DMD) is an X-linked disorder caused by the lack of dystrophin with progressive degeneration of skeletal muscles. Most studies regarding DMD understandably...
Sat Aug 08, 2020 13:31
Related Articles Static and Dynamic Changes of Amplitude of Low-Frequency Fluctuations in Cervical Discogenic Pain. Front Neurosci. 2020;14:733 Authors: Ma M, Zhang H, Liu R, Liu H, Yang X, Yin X, Chen S, Wu X Abstract Cervical discogenic pain (CDP) is a clinically common pain syndrome caused by cervical disk degeneration. A large number of studies have reported that CDP results in brain functional impairments. However, the detailed dynamic...
Sat Aug 08, 2020 13:31
Related Articles NR4A1 Methylation Associated Multimodal Neuroimaging Patterns Impaired in Temporal Lobe Epilepsy. Front Neurosci. 2020;14:727 Authors: Zhi D, Wu W, Xiao B, Qi S, Jiang R, Yang X, Yang J, Xiao W, Liu C, Long H, Calhoun VD, Long L, Sui J Abstract DNA hypermethylation has been widely observed in temporal lobe epilepsy (TLE), in which NR4A1 knockdown has been reported to be able to alleviate seizure severity in mouse model, while...
Sat Aug 08, 2020 13:31
Related Articles Transcranial Magnetic Stimulation Meets Virtual Reality: The Potential of Integrating Brain Stimulation With a Simulative Technology for Food Addiction. Front Neurosci. 2020;14:720 Authors: Stramba-Badiale C, Mancuso V, Cavedoni S, Pedroli E, Cipresso P, Riva G Abstract The aim of this perspective is to propose and discuss the integration of transcranial magnetic stimulation (TMS) over the dorsolateral prefrontal cortex with...
Sat Aug 08, 2020 13:31
Related Articles Cocaine-Induced Synaptic Redistribution of NMDARs in Striatal Neurons Alters NMDAR-Dependent Signal Transduction. Front Neurosci. 2020;14:698 Authors: Delint-Ramirez I, Segev A, Pavuluri A, Self DW, Kourrich S Abstract The consequence of repeated cocaine exposure and prolonged abstinence on glutamate receptor expression in the nucleus accumbens has been extensively studied. However, the early effects of cocaine on NMDAR signaling...
Sat Aug 08, 2020 13:31
Related Articles Examining the Dorsolateral and Ventromedial Prefrontal Cortex Involvement in the Self-Attention Network: A Randomized, Sham-Controlled, Parallel Group, Double-Blind, and Multichannel HD-tDCS Study. Front Neurosci. 2020;14:683 Authors: Martínez-Pérez V, Campoy G, Palmero LB, Fuentes LJ Abstract Background: Attention and perception are strongly biased toward information about oneself compared to information about others. The self-attention...
Sat Aug 08, 2020 13:31
Related Articles Elucidating the Relationship Between Diabetes Mellitus and Parkinson's Disease Using 18F-FP-(+)-DTBZ, a Positron-Emission Tomography Probe for Vesicular Monoamine Transporter 2. Front Neurosci. 2020;14:682 Authors: Kong Y, Zhou H, Feng H, Zhuang J, Wen T, Zhang C, Sun B, Wang J, Guan Y Abstract Diabetes mellitus (DM) and Parkinson's disease (PD) have been and will continue to be two common chronic diseases globally that are...
Sat Aug 08, 2020 13:31
Related Articles Mitochondrial Dysfunction, Neurogenesis, and Epigenetics: Putative Implications for Amyotrophic Lateral Sclerosis Neurodegeneration and Treatment. Front Neurosci. 2020;14:679 Authors: Calió ML, Henriques E, Siena A, Bertoncini CRA, Gil-Mohapel J, Rosenstock TR Abstract Amyotrophic lateral sclerosis (ALS) is a progressive and devastating multifactorial neurodegenerative disorder. Although the pathogenesis of ALS is still not...
Sat Aug 08, 2020 13:31
Related Articles Focused Ultrasound for Noninvasive, Focal Pharmacologic Neurointervention. Front Neurosci. 2020;14:675 Authors: Wang JB, Di Ianni T, Vyas DB, Huang Z, Park S, Hosseini-Nassab N, Aryal M, Airan RD Abstract A long-standing goal of translational neuroscience is the ability to noninvasively deliver therapeutic agents to specific brain regions with high spatiotemporal resolution. Focused ultrasound (FUS) is an emerging technology...
Sat Aug 08, 2020 13:31
Related Articles Functional Validation of CLDN Variants Identified in a Neural Tube Defect Cohort Demonstrates Their Contribution to Neural Tube Defects. Front Neurosci. 2020;14:664 Authors: Baumholtz AI, De Marco P, Capra V, Ryan AK Abstract Neural tube defects (NTDs) are severe malformations of the central nervous system that affect 1-2 individuals per 2,000 births. Their etiology is complex and involves both genetic and environmental factors....
Sat Aug 08, 2020 13:31
Related Articles Interactions of the Brain Renin-Angiotensin-System (RAS) and Inflammation in the Sensitization of Hypertension. Front Neurosci. 2020;14:650 Authors: Xue B, Zhang Y, Johnson AK Abstract Mounting evidence indicates that the renin-angiotensin (RAS) and immune systems interact with one another in the central nervous system (CNS) and that they are importantly involved in the pathogenesis of hypertension. Components comprising the...
Sat Aug 08, 2020 13:31
Related Articles A Conditioning-Strengthened Circuit From CA1 of Dorsal Hippocampus to Basolateral Amygdala Participates in Morphine-Withdrawal Memory Retrieval. Front Neurosci. 2020;14:646 Authors: Ma Q, Fu Y, Cao Z, Shao D, Song J, Sheng H, Yang L, Cui D, Chen M, Zhao F, Luo MH, Lai B, Zheng P Abstract Conditioned context-induced retrieval of drug withdrawal memory contributes to drug relapse. The basolateral amygdala (BLA) is an important...
Sat Aug 08, 2020 13:31
Related Articles Enlightening the Frontiers of Neurogastroenterology Through Optogenetics. Am J Physiol Gastrointest Liver Physiol. 2020 Aug 05;: Authors: Johnson AC, Louwies T, Ligon CO, Greenwood-Van Meerveld B Abstract Neurogastroenterology refers to the study of the extrinsic and intrinsic nervous system circuits controlling the gastrointestinal (GI) tract. Over the past 5-10 years there has been an explosion in novel methodologies, technologies...
Fri Aug 07, 2020 13:16
23 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2020/08/09PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sun Aug 09, 2020 14:48
23 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2020/08/09PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sun Aug 09, 2020 13:49
23 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2020/08/08PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sat Aug 08, 2020 14:52
23 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2020/08/08PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sat Aug 08, 2020 13:52
Related Articles Immunotherapy-based combination strategies for advanced urothelial cancer: A long quest. Cancer. 2020 Aug 05;: Authors: Khaki AR, Agarwal N, Pal SK, Grivas P Abstract LAY SUMMARY: Despite longer survival with immune checkpoint inhibitors targeting programmed cell death protein 1 (PD-1)/programmed cell death-ligand 1 (PD-L1), metastatic urothelial carcinoma remains lethal. There is an unmet need to further improve the efficacy...
Fri Aug 07, 2020 13:59
Effect of functional variant rs11466313 on breast cancer susceptibility and TGFB1 promoter activity.
Related Articles Effect of functional variant rs11466313 on breast cancer susceptibility and TGFB1 promoter activity. Breast Cancer Res Treat. 2020 Aug 05;: Authors: Zhou YT, Zheng LY, Wang YJ, Yang L, Xie YT, Panda I, Tian XX, Fang WG Abstract PURPOSE: This study aimed to investigate whether genetic polymorphisms in TGFB1 contribute to breast cancer (BC) susceptibility, and explore the mechanism of action. METHODS: A total of...
Fri Aug 07, 2020 13:59
Related Articles In situ vaccination with laser interstitial thermal therapy augments immunotherapy in malignant gliomas. J Neurooncol. 2020 Aug 05;: Authors: Shin DH, Melnick KF, Tran DD, Ghiaseddin AP Abstract INTRODUCTION: Laser interstitial thermal therapy (LITT) remains a promising advance in the treatment of primary central nervous system malignancies. As indications for its use continue to expand, there has been growing interest...
Fri Aug 07, 2020 13:59
Related Articles Systemic therapy for metastatic renal cell carcinoma in the first-line setting: a systematic review and network meta-analysis. Cancer Immunol Immunother. 2020 Aug 05;: Authors: Mori K, Mostafaei H, Miura N, Karakiewicz PI, Luzzago S, Schmidinger M, Bruchbacher A, Pradere B, Egawa S, Shariat SF Abstract PURPOSE: Management of metastatic renal cell cancer (mRCC) has undergone a paradigm shift with immune-checkpoint inhibitors...
Fri Aug 07, 2020 13:59
Related Articles Molecular profiling of non-small cell lung cancer. PLoS One. 2020;15(8):e0236580 Authors: Forsythe ML, Alwithenani A, Bethune D, Castonguay M, Drucker A, Flowerdew G, French D, Fris J, Greer W, Henteleff H, MacNeil M, Marignani P, Morzycki W, Plourde M, Snow S, Xu Z Abstract Lung cancer is generally treated with conventional therapies, including chemotherapy and radiation. These methods, however, are not specific to cancer...
Fri Aug 07, 2020 13:59
Related Articles Novel Therapies Potentially Available for Pediatric B-Cell Non-Hodgkin Lymphoma. J Natl Compr Canc Netw. 2020 Aug;18(8):1125-1134 Authors: Harker-Murray PD, Pommert L, Barth MJ Abstract Burkitt lymphoma, diffuse large B-cell lymphoma (DLBCL), and primary mediastinal B-cell lymphoma are the most common aggressive pediatric mature B-cell non-Hodgkin lymphomas (B-NHLs). Despite excellent survival with current chemotherapy...
Fri Aug 07, 2020 13:59
Related Articles Lung cancer management: monitoring and treating resistance development in third generation EGFR TKIs. Expert Rev Anticancer Ther. 2020 Aug 05;: Authors: Franceschini D, Rossi S, Loi M, Chiola I, Piccoli F, Lutman FR, Finocchiaro G, Toschi L, Santoro A, Scorsetti M Abstract INTRODUCTION: Patients treated with third generation EGFR TKIs will develop resistance to treatment at a certain point. Early detection of resistance...
Fri Aug 07, 2020 13:59
Related Articles ENLIVEN study: Pexidartinib for tenosynovial giant cell tumor (TGCT). Future Oncol. 2020 08 05;: Authors: Tap W Abstract Pexidartinib is the first approved medication in the USA for people with tenosynovial giant cell tumor (TGCT). The drug was approved based on the ENLIVEN study, which looked at pexidartinib (brand name, Turalio™), a medication taken by mouth (orally) for people with TGCT (also known as giant cell tumor...
Fri Aug 07, 2020 13:59
Related Articles Molecular Tracing of SARS-CoV-2 in Italy in the First Three Months of the Epidemic. Viruses. 2020 07 24;12(8): Authors: Lai A, Bergna A, Caucci S, Clementi N, Vicenti I, Dragoni F, Cattelan AM, Menzo S, Pan A, Callegaro A, Tagliabracci A, Caruso A, Caccuri F, Ronchiadin S, Balotta C, Zazzi M, Vaccher E, Clementi M, Galli M, Zehender G Abstract The aim of this study is the characterization and genomic tracing by phylogenetic...
Fri Aug 07, 2020 13:59
Related Articles Patient Selection for Adjuvant Chemotherapy in High-Risk Stage II Colon Cancer: A Systematic Review and Meta-Analysis. Am J Clin Oncol. 2020 04;43(4):279-287 Authors: Zhang C, Yin S, Tan Y, Huang J, Wang P, Hou W, Zhang Z, Xu H Abstract OBJECTIVES: Patients with high-risk stage II colon cancer (CC) are recommended to undergo adjuvant chemotherapy (ACT). However, whether such patients can benefit from ACT remains unclear. This...
Fri Aug 07, 2020 13:59
Related Articles To randomize, or not to randomize, that is the question: using data from prior clinical trials to guide future designs. Neuro Oncol. 2019 10 09;21(10):1239-1249 Authors: Vanderbeek AM, Ventz S, Rahman R, Fell G, Cloughesy TF, Wen PY, Trippa L, Alexander BM Abstract BACKGROUND: Understanding the value of randomization is critical in designing clinical trials. Here, we introduce a simple and interpretable quantitative method...
Fri Aug 07, 2020 13:59
Related Articles Postoperative Radiotherapy for Multiple Myeloma of Long Bones: Should the Entire Rod Be Treated? Clin Lymphoma Myeloma Leuk. 2019 08;19(8):e465-e469 Authors: Elhammali A, Milgrom SA, Amini B, Gunther JR, Yoder A, Ludmir EB, Moon B, Weber DM, Thomas SK, Garg N, Manasanch EE, Patel KK, Orlowski RZ, Lee HC, Bird JE, Satcher R, Lin P, Pinnix CC, Dabaja BS Abstract PURPOSE: To characterize local relapse after surgical fixation and...
Fri Aug 07, 2020 13:59
Related Articles Delayed initiation of adjuvant chemotherapy in older women with breast cancer. Cancer Med. 2020 Aug 07;: Authors: Smith-Graziani D, Lei X, Giordano SH, Zhao H, Karuturi M, Chavez-MacGregor M Abstract BACKGROUND: Adjuvant chemotherapy benefits early-stage breast cancer (BC) patients. Older women receive guideline-adherent treatment less frequently and experience treatment delays more frequently. We evaluated factors associated...
Sun Aug 09, 2020 15:51
Related Articles The Third Generation Anti-HER2 Chimeric Antigen Receptor Mouse T Cells Alone or Together With Anti-PD1 Antibody Inhibits the Growth of Mouse Breast Tumor Cells Expressing HER2 in vitro and in Immune Competent Mice. Front Oncol. 2020;10:1143 Authors: Li P, Yang L, Li T, Bin S, Sun B, Huang Y, Yang K, Shan D, Gu H, Li H Abstract Chimeric Antigen Receptor (CAR)-T cells have great efficacy against CD19+ leukemia but little success...
Sun Aug 09, 2020 15:51
Related Articles Nrf2 Inhibitor, Brusatol in Combination with Trastuzumab Exerts Synergistic Antitumor Activity in HER2-Positive Cancers by Inhibiting Nrf2/HO-1 and HER2-AKT/ERK1/2 Pathways. Oxid Med Cell Longev. 2020;2020:9867595 Authors: Yang Y, Tian Z, Guo R, Ren F Abstract The HER2-targeting antibody trastuzumab has shown effectiveness in treating HER2-positive breast and gastric cancers; however, its responses are limited. Currently, Nrf2...
Sun Aug 09, 2020 15:51
Related Articles Patterns of Chest Wall Recurrence and Suggestions on the Clinical Target Volume of Breast Cancer: A Retrospective Analysis of 121 Postmastectomy Patients. Cancer Manag Res. 2020;12:5909-5918 Authors: Wang LW, Li L, Zhang HY, Chen YY, Zhong YH Abstract Purpose: Radiotherapy is a powerful strategy to prevent chest wall recurrence (CWR) of postmastectomy breast cancer (BC). This retrospective study aims at analyzing patterns of...
Sun Aug 09, 2020 15:51
Related Articles The Influence of Pre-Existing Beta-Blockers Use on Survival Outcomes in HER2 Positive Advanced Breast Cancer: Pooled Analysis of Clinical Trial Data. Front Oncol. 2020;10:1130 Authors: Modi ND, Tan JQE, Rowland A, Koczwara B, Kichenadasse G, McKinnon RA, Wiese MD, Sorich MJ, Hopkins AM Abstract Introduction: Beta-blockers (BB) are commonly used to manage cardiovascular disease and may have benefits in controlling complications...
Sat Aug 08, 2020 15:22
Related Articles Evaluation of imaging findings and prognostic factors after whole-brain radiotherapy for carcinomatous meningitis from breast cancer: A retrospective analysis. Medicine (Baltimore). 2020 Jul 31;99(31):e21333 Authors: Okada Y, Abe T, Shinozaki M, Tanaka A, Kobayashi M, Hiromichi G, Kanemaki Y, Nakamura N, Kojima Y Abstract This study aimed to evaluate the imaging findings and prognostic factors after whole-brain radiotherapy...
Fri Aug 07, 2020 14:53
Related Articles Confounded by obesity and modulated by urinary uric acid excretion, sleep-disordered breathing indirectly relates to hyperuricaemia in males: A structural equation model. J Sleep Res. 2020 Aug 06;:e13108 Authors: Lai CH, Huang RJ, Wong JK, Chang SW, Chung AH, Chi YC, Yu YC, Lee SD, Ting H Abstract Sleep-disordered breathing (SDB) causes hypoxic stress and can trigger uric acid (UA) overproduction. We comprehensively investigated...
Sun Aug 09, 2020 15:25
Related Articles Intermittent hypoxia induces turbinate mucosal hypertrophy via upregulating the gene expression related to inflammation and EMT in rats. Sleep Breath. 2020 Aug 06;: Authors: Kuma YI, Hosomichi J, Maeda H, Oishi S, Usumi-Fujita R, Shimizu Y, Kaneko S, Suzuki JI, Yoshida KI, Ono T Abstract PURPOSE: Chronic intermittent hypoxia (IH) plays a pivotal role in the consequences of obstructive sleep apnea (OSA). It has been demonstrated...
Sun Aug 09, 2020 15:25
Related Articles Updates in rare and not-so-rare complications of acromegaly: focus on respiratory function and quality of life in acromegaly. F1000Res. 2020;9: Authors: Langlois F, Suarez GM, Fleseriu M Abstract Acromegaly is a complex disease with excessive growth hormone and insulin-like growth factor 1 (IGF-1) causing multisystem effects, particularly cardiovascular, respiratory, and metabolic. Psychological concerns and poor quality of...
Sun Aug 09, 2020 15:25
Related Articles CPAP Therapeutic Options for Obstructive Sleep Apnea. Pragmat Obs Res. 2020;11:67-76 Authors: Hooper RG Abstract Introduction: There are many options available to patients who are placed on constant positive airway pressure (CPAP) for obstructive sleep apnea. Despite the success of CPAP in correcting apnea, a significant number of patients have difficulty with the therapy. A large number of those patients who have difficulty...
Sun Aug 09, 2020 15:25
Related Articles The Evaluation of Autonomic Arousals in Scoring Sleep Respiratory Disturbances with Polysomnography and Portable Monitor Devices: A Proof of Concept Study. Nat Sci Sleep. 2020;12:443-451 Authors: Mayer P, Herrero Babiloni A, Beetz G, Marshansky S, Kaddaha Z, Rompré PH, Jobin V, Lavigne GJ Abstract Background: Autonomic arousals can be considered as surrogates of electroencephalography (EEG) arousals when calculating respiratory...
Sun Aug 09, 2020 15:25
Related Articles Obstructive Sleep Apnea Exacerbates Glucose Dysmetabolism and Pancreatic β-Cell Dysfunction in Overweight and Obese Nondiabetic Young Adults. Diabetes Metab Syndr Obes. 2020;13:2465-2476 Authors: Li N, Fan Y, Zhou JP, Maimba OD, Zhang L, Li QY Abstract Purpose: This study aimed to investigate the effects of obstructive sleep apnea (OSA) on the pancreatic β-cells dysfunction and their implications in the glucose dysmetabolism...
Sun Aug 09, 2020 15:25
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