We investigated differences in the technical quality of root fillings according to socioeconomic status. In the Finnish Health 2000 Survey, which comprised a sample of 8,028 adults aged over 29 yr, 6,115 underwent panoramic radiography. A total of 7,986 endodontically treated teeth were detected among 3,095 participants. The criterion for a technically inadequate root filling was a distance from the root filling to the root apex of over 3 mm or a filling extruding beyond the apex. Educational level,...
Sun Aug 09, 2020 20:34
Abstract Management of advanced hormone‐naïve prostate cancer (HNPC) is a critical public health issue. Useful prognostic markers are thus needed to select patients who will benefit from recently introduced upfront therapies. p16 expression is an adverse prognostic marker in prostate cancer. The present study aimed to determine whether p16 expression would serve as an adverse prognostic marker in advanced HNPC. A total of 79 patients diagnosed by needle biopsy with adenocarcinoma Gleason score ≥8...
Sun Aug 09, 2020 20:53
Background Chest radiography is often used to detect lung involvement in patients with suspected pneumonia. Chest radiography through glass walls of an isolation room is a technique that could be immensely useful in the current COVID-19 pandemic. Purpose The purpose of this study was to ensure quality and radiation safety while acquiring portable chest radiographs through the glass doors of isolation rooms using an adult anthropomorphic thorax phantom. Materials and Methods ...
Fri Aug 07, 2020 03:00
Abstract Background Clinical course following failure of human papillomavirus (HPV)‐positive oropharyngeal cancers (HPV + OPC) is poorly understood. This study aims to characterize disease course following failure after transoral robotic surgery (TORS). Methods We identified patients with HPV + OPC‐treated upfront with TORS at our institution from 2007 to 2017. HPV status was confirmed with immunohistochemistry or HPV DNA polymerase chain reaction. Patient characteristics, treatment modalities,...
Sun Aug 09, 2020 21:50
Abstract Background Reirradiation of head and neck cancer is associated with high rates of locoregional failure and potentially severe treatment‐related toxicity. We report our institutional experience of reirradiation using modern highly conformal radiotherapy approaches in patients with prior oropharyngeal radiation. Methods We reviewed patients receiving curative‐intent reirradiation with intensity‐modulated radiation therapy, stereotactic body radiation therapy, and proton beam radiotherapy...
Sun Aug 09, 2020 21:45
Abstract The diagnostic work‐up of atopic dermatitis (AD, atopic eczema) was discussed in part I. This part of the medical algorithm focuses on the therapy of AD in early childhood and is based on recent literature and international guidelines. The management of AD is mainly based on disease severity, which has already been discussed in part I. Basic therapy of the disturbed skin barrier is always necessary, i.e. also for children that do not suffer from active lesions. Normally, topical treatment...
Sun Aug 09, 2020 18:59
Background The objective of this study was to determine whether standardized treatment of germ cell tumors (GCTs) could overcome sociodemographic factors limiting patient care. Methods The records of all patients undergoing primary treatment for GCTs at both a public safety net hospital and an academic tertiary care center in the same metropolitan area were analyzed. Both institutions were managed by the same group of physicians in the context of multidisciplinary cancer care. Patients were...
10:40
Many inorganic materials can form crystals but little is known about their enantioselective crystallization. In this article, we report on the enantioselective crystallization of ε‐Zn(OH) 2 (Wulfingite) chiral crystals using amino acids. Crystals of ε‐Zn(OH) 2 were crystallized from supersaturated sodium‐hydroxide and zinc‐nitrate aqueous solutions in the presence of L‐ or D‐Arginine. All our chiral measurements, such as selective chiral adsorption by circular dichroisem (CD) /chiral chromatography...
Sun Aug 09, 2020 17:14
Monitoring multiple molecular probes simultaneously establishes their correlations and reveal the holistic mechanism. Current fluorescence imaging, however, is limited to about four colors because of typically ~100‐nm spectral width. Here we show that molecular supracence imparts superior spectral resolution, resolving eight colors in 300‐nm width, about 37.5‐nm per color. A recently discovered light‐molecule interacting phenomenon, supracence only measures molecular emission above its excitation...
Sun Aug 09, 2020 17:14
Abstract Background Randomized controlled trials (RCT) generalizability may be limited due to strict patient selection. Objective In a real‐world heart failure (HF) population, we assessed eligibility for sacubitril/valsartan based on PARADIGM‐HF (sacubitril/valsartan effective) / PARAGON‐HF [sacubitril/valsartan effective in mildly‐reduced ejection fraction (EF)]. Methods Outpatients from the Swedish HF Registry (SwedeHF) were analyzed. In SwedeHF, EF is recorded as...
Sun Aug 09, 2020 20:07
Abstract We read with great interest the comment by Suarez‐Perez et al. on our article.[1] We share their concerns regarding the need for a cautious interpretation of antiphospholipid antibodies (aPLA) positivity in patients with coronary virus disease 2019 (COVID‐19). Herein, we would like to add further insights in the discussion.
Sun Aug 09, 2020 11:55
A young woman with mixed connective tissue disease complicated by erosive arthritis, secondary hypogammaglobulinemia due to rituximab, and a history of many infectious complications developed multiple nonhealing wounds, polyarticular joint pain, and leukocytosis. Radiographic studies demonstrated multiple scattered areas of osteomyelitis and complex abscesses. Purulent fluid drained from multiple sites did not yield a microbiologic diagnosis by standard culture technique, but Mycoplasma orale was...
08:20
Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN01208D, PaperYun Zhang, Peng Song, Bingyuan Guo, Wenying Hao, Lei Liu, Hai-Chen WuWe have developed a bifunctional probe based on triplex molecular beacons for the measurement of environmental pH and the quantification of microRNA-10b in nanopore. The probe responds sharply to solution...The content of this RSS Feed (c) The Royal Society of Chemistry
02:00
Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN01390K, PaperXianli Wang, Chuanzhen Hu, Kaiqin Chu, Zachary James SmithThe majority of problems in analytical Raman spectroscopy are mathematically over-determined, where many more spectral variables are measured than analytic outputs (such as chemical concentrations) are calculated. Thus, to improve...The content of this RSS Feed (c) The Royal Society of Chemistry
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ALL authors HAVE NO CONFLICTS OF INTEREST
Sun Aug 09, 2020 03:00
Malaria is one of the major contributing risk factors for poor development of children living in low- and middle-income countries (LMICs). However, little is known about the specific domains of cognition and b...
Sun Aug 09, 2020 03:00
Healthcare workers (HCWs) are at particular risk during pandemics and epidemics of highly virulent diseases with significant morbidity and case fatality rate. These diseases include severe acute respiratory sy...
Sat Aug 08, 2020 03:00
Home-based hospitalization (HBH) offers an alternative delivery model to hospital care. There has been a remarkable increase in pilot initiatives and deployment of this model to optimize services offered to a ...
Sat Aug 08, 2020 03:00
The aims of this study were to survey the occurrence of acute medical situations in Dutch orthodontic practice and to examine the self-perceived competence of orthodontists in managing acute medical emergencies.
03:00
Abstract To design machine learning classifiers to facilitate the clinical use and increase the accuracy of the forced oscillation technique (FOT) in the differential diagnosis of patients with asthma and restrictive respiratory diseases. FOT and spirometric exams were performed in 97 individuals, including controls (n = 20), asthmatic patients (n = 38), and restrictive (n = 39) patients. The first experiment of this study showed that the best FOT parameter was the resonance frequency,...
03:00
Abstract Classification of cancerous genes from microarray data is an important research area in bioinformatics. Large amount of microarray data are available, but it is very costly to label them. This paper proposes an active learning model, a semi-supervised classification approach, to label the microarray data using which predictions can be made even with lesser amount of labeled data. Initially, a pool of unlabeled instances is given from which some instances are randomly chosen...
Sat Aug 08, 2020 03:00
Abstract An efficient and novel modeling approach is proposed in this paper for identifying proteins or genes involved in melanoma skin cancer. Two types of classifiers are modeled, based on the chemical structure and hydropathy property of amino acids. These classifiers are further implemented using NI LabVIEW–based hardware kit to observe the real-time response for proper diagnosis. The phase responses, pole-zero diagrams, and transient responses are examined to screen out the...
Sat Aug 08, 2020 03:00
Mucosal Immunology, Published online: 09 August 2020; doi:10.1038/s41385-020-0333-3Coordinated co-migration of CCR10+ antibody-producing B cells with helper T cells for colonic homeostatic regulation
Sun Aug 09, 2020 03:00
Abstract Purpose The aim of this prospective study was to validate the diagnostic performance of computed tomography angiography (CTA) in endoprosthesis stenosis in the superior mesenteric artery (SMA) using mean arterial pressure (MAP) gradients during angiography as a reference method. Methods Twenty-nine patients with mesenteric atherosclerotic disease...
Sun Aug 09, 2020 03:00
Abstract Purpose MR elastography (MRE) has a low technical failure rate in patients with chronic liver disease. The failure rate in an unscreened population is unknown. The purpose of this study was to determine the technical failure rate of MRE in patients with no known liver disease. Methods In this prospective trial, 633 patients received 673 scans on...
Sun Aug 09, 2020 03:00
Abstract Dual-energy CT (DECT) can be defined as the use of two different energy levels to identify and quantify material composition. Since its inception, DECT has benefited from remarkable improvements in hardware and clinical applications. DECT enables accurate identification and quantification of multiple materials, including fat, iron, and iodine. As a consequence, multiple studies have investigated the potential role of DECT in the assessment of diffuse liver diseases. While...
Sat Aug 08, 2020 03:00
Abstract Purpose Small bowel obstruction (SBO) is a common cause of emergency presentations for abdominal pain and can be complicated by mesenteric ischemia. Computed tomography is currently central to diagnosis and management planning. Currently accepted signs identify secondary effects of the root physiological insult, which is vascular obstruction. We hypothesized that with advancements in CT technology and reconstruction algorithms,...
Sat Aug 08, 2020 03:00
Abstract Purpose To measure spleen stiffness by shear wave elastography (SWE) using acoustic radiation force impulse (ARFI) in patients with splenomegaly and to evaluate utility of elastography technique in identifying etiology of splenomegaly. Methods Sixty-one treatment-naïve patients with splenomegaly were enrolled. The control group consisted of 20 healthy...
Sat Aug 08, 2020 03:00
La pirámide lógica El asunto de esta entrada es muy sencillo de explicar y con el gráfico uno puede perfectamente hacerse a la idea de lo que digo.La lógica aristotélica, en la que a partir de dos premisas se extraía una conclusión nos parece hoy cosa de sentido común.Si alguien hace una afirmación falsa del tipo: "los balones de fútbol son cuadrados" como primera premisa para un razonamiento lógico, resulta difícil seguir adelante con dicho razonamiento, dado que la premisa es falsa. No obstante...
Sun Aug 09, 2020 18:12
The COVID-19 pandemic has resulted in an unprecedented healthcare crisis with a high prevalence of psychological distress in healthcare providers. We sought to document the prevalence of burnout syndrome among...
Sat Aug 08, 2020 03:00
Red blood cell (RBC) transfusions are associated with risks including immunological reactions and volume overload. Current guidelines suggest a restrictive transfusion strategy in most patients with sepsis but...
Sat Aug 08, 2020 03:00
Abstract Background The evaluation of voice quality with acoustic measurements is useful to objectify the diagnostic process. Particularly, breathiness was highly evaluated and the Acoustic Breathiness Index (ABI) might have promising features. Objective of review The goal of the present meta‐analysis is to quantify, from existing cross‐validation studies, the evidence for the diagnostic accuracy of ABI, including its sensitivity and specificity. Type of review Meta‐analysis Search...
Sat Aug 08, 2020 13:59
Abstract Chronic cases of otitis externa, resistant to conventional treatments are notoriously difficult to treat, with resolution in these casesbeing challenging. Guidelines suggest the use of corticosteroid in chronic otitis externa, however, there is no specific advice on which corticosteroid to utilise. Our case‐series demonstrates the potential benefit of fluticasone propionate in patients who have previously failed a multitude of conventional management options. Despite the limitations...
Sat Aug 08, 2020 11:39
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