Evaluating Drug Fever to Beta Lactam Antibiotics

Evaluating Drug Fever to Beta Lactam Antibiotics: Drug fever is a rare and frequently overlooked reaction to medications. Drug fever is often missed, as fever is commonly miscategorized as infectious, and drug fever is a diagnosis of exclusion. Drug fevers typically occur within days to weeks after starting the culprit medication and cease after stopping the medication.1 Patients are otherwise well with no other symptoms. Many different medications have been implicated in drug fever.1-5 The true incidence of drug fever is unknown, but it is likely underreported.