Hypereosinophilia with Angioimmunoblastic T cell Lymphoma 1

Hypereosinophilia with Angioimmunoblastic T cell Lymphoma 1: A 58-year-old woman was evaluated for persistent eosinophilia. She had joint pain with effusions for 14 years and was treated for presumptive seronegative rheumatoid arthritis with prednisone and multiple disease-modifying antirheumatic drugs with minimal improvement (timeline in Figure 1). For 2.5 years prior to evaluation, she developed a persistent pruritic rash, chronic cough, and a 20 pound weight loss. She had no atopic history and was not taking any herbal supplements. She did travel to Mexico and the US Virgin Islands within the past 2 years.