Abstract The incidence of cutaneous melanoma and the mortality rate of advanced melanoma patients continues to rise globally. Despite the recent success of immunotherapy including ipilimumab and pembrolizumab checkpoint inhibitors, a large proportion of patients are refractory to such treatment modalities. The application of mycobacteria such as Bacillus Calmette‐Guérin (BCG) in the treatment of various malignancies, including cutaneous melanoma, has been clearly demonstrated after almost...
Wed Mar 04, 2020 14:08
Abstract Background Nonalcoholic fatty liver disease (NAFLD) is a rising global disease associated with clinical and economic burdens. Objectives We aimed to quantify NAFLD prevalence and awareness to provide stakeholders necessary information to combat NAFLD burden. Methods This study utilizes data from the National Health and Nutrition Examination Survey 2011–2016 and included 4538 adult participants who did not have heavy drinking or viral hepatitis history. The US fatty...
Wed Mar 04, 2020 12:08
Publication date: Available online 4 March 2020Source: Seminars in OncologyAuthor(s): Eric J. Chow, Kirsten K. Ness, Gregory T. Armstrong, Nickhill Bhakta, Jennifer M. Yeh, Smita Bhatia, Wendy Landier, Louis S. Constine, Melissa M. Hudson, Paul C. Nathan
Wed Mar 04, 2020 14:03
Related ArticlesHelping the Radiologist: The Role of Scientific Journals to Help Prevent the Spread of COVID-19. Radiology. 2020 Mar 03;:200661 Authors: Li X, Qian Y, Liu B, Yu Y PMID: 32125934 [PubMed - as supplied by publisher]
Wed Mar 04, 2020 13:58
Related ArticlesPediatric Chest Radiographic and CT Findings of Electronic Cigarette or Vaping Product Use-associated Lung Injury (EVALI). Radiology. 2020 Mar 03;:192778 Authors: Artunduaga M, Rao D, Friedman J, Kwon JK, Pfeifer CM, Dettori A, Winant AJ, Lee EY Abstract Background Electronic cigarette or vaping product use-associated lung injury (EVALI) is a serious public health concern with substantial morbidity and mortality, particularly in young...
Wed Mar 04, 2020 13:58
Related ArticlesRemoval of Antiscatter Grids for Spinal Digital Subtraction Angiography: Dose Reduction without Loss of Diagnostic Value. Radiology. 2020 Mar 03;:191786 Authors: Orrù E, Mekabaty AE, Millan DS, Pearl MS, Gailloud P Abstract Background Spinal digital subtraction angiography (DSA) exposes patients and operators to substantial amounts of radiation. Antiscatter grid (ASG) removal is used to decrease radiation exposure but may reduce image...
Wed Mar 04, 2020 13:58
Related ArticlesDrug-coated Balloon Angioplasty of Femoropopliteal Lesions Maintained Superior Efficacy over Conventional Balloon: 2-year Results of the Randomized EffPac Trial. Radiology. 2020 Mar 03;:191619 Authors: Teichgräber U, Lehmann T, Aschenbach R, Scheinert D, Zeller T, Brechtel K, Blessing E, Lichtenberg M, von Flotow P, Heilmeier B, Sixt S, Brucks S, Erbel C, Beschorner U, Werk M, Riambau V, Wienke A, Klumb CT, Thieme M Abstract Background...
Wed Mar 04, 2020 13:58
Related ArticlesThe Relationship between MRI Radiofrequency Energy and Function of Nonconditional Implanted Cardiac Devices: A Prospective Evaluation. Radiology. 2020 Mar 03;:191132 Authors: Rahsepar AA, Zimmerman SL, Hansford R, Guttman MA, Castro V, McVeigh D, Kirsch JE, Halperin HR, Nazarian S Abstract Background The risks associated with MRI in individuals who have implanted cardiac devices are thought to arise from the interaction between the...
Wed Mar 04, 2020 13:58
Related ArticlesLiver Stiffness Measured with Two-dimensional Shear-Wave Elastography Is Predictive of Liver-related Events in Patients with Chronic Liver Disease Due to Hepatis B Viral Infection. Radiology. 2020 Mar 03;:191481 Authors: Wu M, Wu L, Jin J, Wang J, Li S, Zeng J, Guo H, Zheng J, Chen S, Zheng R Abstract Background Liver stiffness measurement has been proposed as a noninvasive marker for predicting liver-related complications of cirrhosis....
Wed Mar 04, 2020 13:58
Related ArticlesAxillary Nodal Burden Assessed with Pretreatment Breast MRI Is Associated with Failed Sentinel Lymph Node Identification after Neoadjuvant Chemotherapy for Breast Cancer. Radiology. 2020 Mar 03;:191639 Authors: Kim WH, Kim HJ, Park CS, Lee J, Park HY, Jung JH, Kim WW, Chae YS, Lee SJ, Kim SH Abstract Background After publication of the findings of the American College of Surgeons Oncology Group Z1071 trial, sentinel lymph node biopsy...
Wed Mar 04, 2020 13:58
Related ArticlesStenotrophomonas maltophilia spondylodiscitis following lumbar microdiscectomy mimicking a cotton granuloma: A case report and literature review. Surg Neurol Int. 2020;11:28 Authors: Adsul NM, Panigrahi V, Acharya S, Kalra KL, Chahal RS Abstract Background: Vertebral osteomyelitis caused by Stenotrophomonas maltophilia is very rare. There are only two cases reported in literature. Here, we present a 48-year-old immunocompetent male who,...
Wed Mar 04, 2020 13:57
Related ArticlesThe relationship between preoperative predictive factors for clinical outcome in patients operated for lumbar spinal stenosis by decompressive laminectomy. Surg Neurol Int. 2020;11:27 Authors: Mauro D, Nasi D, Paracino R, Capece M, Carrassi E, Aiudi D, Mancini F, Lattanzi S, Colasanti R, Iacoangeli M Abstract Background: Our hypothesis was that by identifying certain preoperative predictive factors, we could favorably impact clinical...
Wed Mar 04, 2020 13:57
Related ArticlesFetal subependymal giant cell astrocytoma: A case report and review of the literature. Surg Neurol Int. 2020;11:26 Authors: Karagianni A, Karydakis P, Giakoumettis D, Nikas I, Sfakianos G, Themistocleous M Abstract Background: Subependymal giant cell astrocytomas (SEGAs) appear approximately in 10% of patients with tuberous sclerosis. These tumors are most commonly diagnosed in childhood and adolescence, with in utero diagnosed SEGAs...
Wed Mar 04, 2020 13:57
Related ArticlesCost comparison among punctate midline myelotomy, intrathecal pain pump, and spinal cord epidural stimulator. Surg Neurol Int. 2020;11:25 Authors: Aljuboori Z, Meyer K, Sharma M, Ball T, Nauta H Abstract Background: Invasive pain procedures can be valuable tools to manage chronic pain. Here, we compared the costs of three procedures used to address chronic pain; punctate midline myelotomy (PMM), placement of a spinal cord stimulator (SCS),...
Wed Mar 04, 2020 13:57
Related ArticlesUtilizing vertebral body autograft for anterior cervical corpectomy/fusion. Surg Neurol Int. 2020;11:24 Authors: Hoffman H, Goulart CR, Galgano MA Abstract Background: There are numerous ways to reconstruct cervical vertebral bodies and achieve arthrodesis following anterior cervical corpectomy and fusion (ACF). However, device and donor site complications abound. Here, we describe a novel technique for performing ACF using the vertebral...
Wed Mar 04, 2020 13:57
Related ArticlesThe role of full-endoscopic lumbar discectomy in patients with neurodegenerative disorders: Technical note and short literature review. Surg Neurol Int. 2020;11:23 Authors: Kapetanakis S, Gkantsinikoudis N, Thomaidis T, Theodosiadis P Abstract Background: Motor neuron disease includes a spectrum of neurodegenerative diseases with progressive courses and unfavorable prognoses. Here, we described a patient with a lumbar disc herniation...
Wed Mar 04, 2020 13:57
Related ArticlesParietal transventricular approach for medial temporal glioma: A technical report. Surg Neurol Int. 2020;11:22 Authors: Kumar A, Chandra P, Kale S Abstract Background: Medial temporal lobectomy (MTLy) poses a surgical challenge due to convoluted anatomy of medial temporal lobe (MTL). Various approaches have been described to access MTL for removing various pathologies. We, hereby, describe the parietal transventricular approach for removing...
Wed Mar 04, 2020 13:57
Related ArticlesAdaptive radiosurgery based on two simultaneous dose prescriptions in the management of large renal cell carcinoma brain metastases in critical areas: Towards customization. Surg Neurol Int. 2020;11:21 Authors: Sinclair G, Stenman M, Benmakhlouf H, Johnstone P, Wersäll P, Lindskog M, Hatiboglu MA, Harmenberg U Abstract Background: The long-term benefits of local therapy in metastatic renal cell carcinoma (mRCC) have been widely documented....
Wed Mar 04, 2020 13:57
Related ArticlesUnilateral atlantoaxial pseudoarticulation: A case report, literature review, and proposed mechanism. Surg Neurol Int. 2020;11:20 Authors: Eaton RG, Viljoen SV Abstract Background: Atlantoaxial pseudoarticulation rarely involves the cervical spine, and its etiology is unclear. In theory, pseudoarticulation is comparable to Bertolotti's syndrome in the lumbar spine or may be attributed to an aberrant focal fusion between C0-C1-C2 that...
Wed Mar 04, 2020 13:57
Related ArticlesTraumatic cervical spine injury: Short-and medium-term prognostic factors in 102 patients. Surg Neurol Int. 2020;11:19 Authors: Abboud H, Ziani I, Melhaoui A, Arkha Y, Elouahabi A Abstract Background: Traumatic cervical spine injuries (CSIs) can be defined as osteodiscoligamentous lesions and are frequent in the young and active population. These lesions are often associated with significant devastating neurological deficits. Here, we...
Wed Mar 04, 2020 13:57
Related ArticlesSymptomatic pulmonary cement embolism after pedicle screw polymethylmethacrylate cement augmentation: A case report and review. Surg Neurol Int. 2020;11:18 Authors: Rahimizadeh A, Hassani V, Soufiani H, Rahimizadeh A, Karimi M, Asgari N Abstract Background: In osteoporotic patients, a useful technique for significantly enhancing the strength of a pedicle screw is augmentation with polymethylmethacrylate cement. However, a rare complication...
Wed Mar 04, 2020 13:57
Related ArticlesSpinal intramedullary epidermoid cysts: Three case presentations and literature review. Surg Neurol Int. 2020;11:17 Authors: Rahimizadeh A, Sharifi G Abstract Background: True intramedullary epidermoid cysts (IECs) not associated with congenital anomalies or previous spinal procedures are extremely rare. In a review of the literature since 1992, only 29 such cases have been reported. Here, we add three new cases in this category. ...
Wed Mar 04, 2020 13:57
Efficacy of a topical gelatin-thrombin hemostatic matrix, FLOSEAL®, in intracranial tumor resection.
Related ArticlesEfficacy of a topical gelatin-thrombin hemostatic matrix, FLOSEAL®, in intracranial tumor resection. Surg Neurol Int. 2020;11:16 Authors: Kamamoto D, Kanazawa T, Ishihara E, Yanagisawa K, Tomita H, Ueda R, Jinzaki M, Yoshida K, Toda M Abstract Background: Hemostasis plays an important role in safe brain tumor resection and also reduces the risk for surgical complications. This study aimed to evaluate the efficacy of FLOSEAL®, a topical...
Wed Mar 04, 2020 13:57
Related ArticlesSkeletal muscle of the fetus: A window on the cellular basis of intrauterine growth restriction. J Physiol. 2020 Mar 03;: Authors: Wood CE PMID: 32126151 [PubMed - as supplied by publisher]
Wed Mar 04, 2020 13:55
Publication date: Available online 4 March 2020Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Graham Pawelec
Wed Mar 04, 2020 13:55
Related ArticlesDiagnosis and Treatment of Parasellar Lesions. Neuroendocrinology. 2020 Mar 04;: Authors: Gatto F, Perez-Rivas LG, Olarescu NC, Khandeva P, Chachlaki K, Trivellin G, Gahete MD, Cuny T Abstract The parasellar region, located around the sella turcica, is an anatomically complex area representing a crossroads for important adjacent structures. Several lesions -including tumoral, inflammatory vascular- and infectious diseases may affect this...
Wed Mar 04, 2020 13:50
Related ArticlesHypofractionated Robotic Stereotactic Radiosurgery for Vagal Paragangliomas: A Novel Treatment Strategy for Cranial Nerve Preservation. Otolaryngol Head Neck Surg. 2020 Mar 03;:194599820910150 Authors: Maxwell AK, Mehta GU, Muelleman T, Barnard ZR, Hartwick T, Mak A, Brackmann DE, Lekovic GP Abstract OBJECTIVE: To provide the first description of hypofractionated stereotactic radiosurgery (SRS) and evaluate tumor control and safety for...
Wed Mar 04, 2020 13:50
Related ArticlesAvoiding repeated surgery in patients with acute invasive fungal sinusitis. Eur Arch Otorhinolaryngol. 2020 Mar 03;: Authors: Malleshappa V, Rupa V, Varghese L, Kurien R Abstract PURPOSE: We aimed to ascertain whether using an aggressive initial surgical protocol would reduce the need for repeated sinus surgery in patients with acute invasive fungal sinusitis (AIFS). METHODS: Patients with AIFS prospectively underwent clinicoradiological...
Wed Mar 04, 2020 13:50
Related ArticlesDiagnostic accuracy of computed tomography and magnetic resonance imaging compared to surgical exploration for anterior skull base and medial orbital wall infiltration in advanced sinonasal tumors. Head Neck. 2020 Mar 02;: Authors: Meerwein CM, Pazahr S, Soyka MB, Hüllner MW, Holzmann D Abstract BACKGROUND: Knowledge of medial orbital wall (MOW) and anterior skull base (ASB) infiltration is of uttermost importance for staging and therapy...
Wed Mar 04, 2020 13:50
Related ArticlesSurgical Treatment and Outcomes for Sinonasal and Skull Base Phosphaturic Mesenchymal Tumors. Otolaryngol Head Neck Surg. 2020 Mar 03;:194599820904055 Authors: Tang R, Mao S, Lin H, Ye HB, Li DW, Chen ZN, Su KM, Zhang WT Abstract OBJECTIVE: To describe our clinical experience with surgical treatments for sinonasal phosphaturic mesenchymal tumors diagnosed at our institution. STUDY DESIGN: Retrospective case series. SETTING:...
Wed Mar 04, 2020 13:50
Related ArticlesUse of an acrylic jig to aid orbital reconstruction after resection of a sphenoid intraosseous meningioma: a technical note. Br J Oral Maxillofac Surg. 2019 12;57(10):1156-1157 Authors: Williams JV, Parmar JD, Carter LM, Woodhead P, Corns R PMID: 31594717 [PubMed - indexed for MEDLINE]
Wed Mar 04, 2020 13:50
Related ArticlesRhinogenic headache in pediatric and adolescent patients: an evidence-based review. Int Forum Allergy Rhinol. 2019 05;9(5):443-451 Authors: Smith BC, George LC, Svider PF, Nebor I, Folbe AJ, Sheyn A, Johnson AP, Eloy JA Abstract BACKGROUND: Although some causes of rhinogenic headache, such as acute sinusitis, have clear diagnostic criteria, others, such as "sinus headache" and mucosal contact points, are more nebulous. Misdiagnosis of...
Wed Mar 04, 2020 13:50
Nature Communications, Published online: 04 March 2020; doi:10.1038/s41467-020-15016-2Lead halide perovskite quantum dots (PQDs) promise applications in optoelectronics but are limited by sensitivity to wet environments. Here the authors develop a Pb-S bonding approach to synthesize PQDs@silica nanodots that are capable of emitting and lasing in aqueous environments for long periods.
Wed Mar 04, 2020 02:00
Nature Communications, Published online: 04 March 2020; doi:10.1038/s41467-020-15037-xPerovskites are appealing for optoelectronics, but high-quality perovskite single crystals should be grown at low temperature to minimize trap density. Here, the authors report a room-temperature liquid-diffused-induced crystallization for growth of high-quality hybrid perovskite single crystals.
Wed Mar 04, 2020 02:00
Nature Communications, Published online: 04 March 2020; doi:10.1038/s41467-020-14996-5The development of artificial 3D soft materials and device systems that can reproduce the nonlinear, anisotropic mechanical properties of biological tissues remains challenging. Here, the authors design a class of soft 3D network materials that can offer defect-insensitive, nonlinear mechanical responses closely matched with those of biological tissues.
Wed Mar 04, 2020 02:00
Nature Communications, Published online: 04 March 2020; doi:10.1038/s41467-020-14840-wGram-positive bacteria can release signaling peptides that are ‘probed’ by intracellular receptors after being pumped into the cytoplasm. Here, Babel et al. show that these pump-probe networks can infer the fraction of signal-producing cells in a mixed population, and do not necessarily mediate typical quorum-sensing control.
Wed Mar 04, 2020 02:00
Nature Communications, Published online: 04 March 2020; doi:10.1038/s41467-020-15013-5Identifying economic and ecological trade-offs of land-use transitions is important to ensure sustainability. Here, Grass et al. find biodiversity-profit trade-offs in tropical land-use transitions in Sumatra, and show that targeted landscape planning is needed to increase land-use efficiency while ensuring socio-ecological sustainability.
Wed Mar 04, 2020 02:00
Nature Communications, Published online: 04 March 2020; doi:10.1038/s41467-020-15020-6How traits specific to modern humans have evolved is difficult to study. Here, Gokhman et al. compare measured and reconstructed DNA methylation maps of present-day humans, archaic humans and chimpanzees and find that genes that affect vocal tract and facial anatomy show methylation changes between archaic and modern humans.
Wed Mar 04, 2020 02:00
Nature Communications, Published online: 04 March 2020; doi:10.1038/s41467-020-14975-wDiagnosing acute infections based on transcriptional host response shows promise, but generalizability is wanting. Here, the authors use a co-normalization framework to train a classifier to diagnose acute infections and apply it to independent data on a targeted diagnostic platform.
Wed Mar 04, 2020 02:00
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