Borophene sheets have been synthesized in recent experiments, but the metallic nature and structural instability of the sheets seriously prevent the outstanding emerging applications. Hydrogenated borophene has been predicted as an ideal material for nanoelectronic applications due to its high stability and excellent electronic and mechanical properties. However, the fabrication of hydrogenated borophene has still a great challenge. Here, we demonstrate that hydrogenated borophenes in large quantities...
Fri Apr 03, 2020 17:50
With the development of new photocatalytic methods over recent decades, the translation of these chemical reactions to industrial production scales using continuous flow reactors has become a topic of increasing interest. In this context, we describe our studies toward elucidating an empirically‐derived parameter for scaling photocatalytic reactions in flow. By evaluating the performance of a photocatalytic C‐N cross‐coupling across multiple reactor sizes and geometries, it was demonstrated that...
Fri Apr 03, 2020 17:50
Nucleic acid amplification tests (NAATs) integrated on a chip hold great promises for early disease diagnosis at the point of care. Currently, nucleic acid (NA) purification remains complicated, time‐consuming and labor‐intensive, and it takes extensive efforts to optimize the amplification chemistry. Using selective electrokinetic concentration, we report one‐step, liquid‐phase NA purification that is much simpler and faster than conventional solid phase extraction. By further re‐concentrating NAs...
Fri Apr 03, 2020 17:06
Hierarchically porous metal–organic frameworks (HP‐MOFs) facilitate mass transfer due to mesoporosity while preserving the advantage of microporosity. This unique feature endows HP‐MOFs with remarkable application potential in multiple fields. Recently, new methods such as linker labilization for the construction of HP‐MOFs have emerged. To further enrich the synthetic toolkit of MOFs, we report a controlled photolytic removal of linkers to create mesopores within microporous MOFs at tens of milliseconds....
Fri Apr 03, 2020 11:04
Cover Caption: The cover image is based on the Original Article CtBP1 transactivates RAD51 and confers cisplatin resistance to breast cancer cells by Yu Deng, Fulun Li, Wanjun Guo et al., https://doi.org/10.1002/mc.23175.
Sat Apr 04, 2020 18:22
Abstract Background Desmosomes are intercellular cadherin‐mediated adhesion complexes that anchor intermediate filaments to the cell membrane and are required for strong adhesion for tissues under mechanical stress. One specific component of desmosomes is plakophilin‐1 (PKP1), which is mainly expressed in the spinous layer of the epidermis. Loss‐of‐function autosomal recessive mutations in PKP1 result in ectodermal dysplasia‐skin fragility (EDSF) syndrome, the initial inherited Mendelian disorder...
Sun Apr 05, 2020 11:21
Sat Apr 04, 2020 20:39
Abstract Background Understanding the discrepancy between IgE sensitization and allergic reactions to peanut could facilitate diagnosis and lead to novel means of treating peanut allergy. Objective To identify differences in IgE and IgG4 binding to peanut peptides between peanut allergic (PA) and peanut sensitized but tolerant (PS) children. Methods PA (n=56), PS (n=42) and non‐sensitized non‐allergic (NA, n=10) patients were studied. Synthetic overlapping 15‐mer peptides...
Sat Apr 04, 2020 20:28
Abstract Background Betalactam (BL) antibiotics are the most common cause of drug hypersensitivity. Amoxicillin (AX), which is often prescribed alongside clavulanic acid (Clav), is the most common elicitor. The aim of this study was to determine whether AX and Clav‐responsive T‐cells are detectable in patients with immediate hypersensitivity to AX‐Clav, to assess whether these T‐cells display the same specificity as that detected in skin and provocation testing and to explore T‐cell activation...
Sat Apr 04, 2020 17:15
Fri Apr 03, 2020 20:20
Fri Apr 03, 2020 18:30
Abstract Background Successful vascular anastomosis is essential for the survival of free tissue transfer. The aim of the study is to review the current literature and perform a meta‐analysis to assess the potential advantages of a mechanical anastomosis coupler device (MACD) over the hand‐sewn (HS) technique for venous anastomoses. Methods A systematic Medline search was performed to gather all reports of articles related to MACD from 1984 until now. The following data were extracted:...
Sat Apr 04, 2020 17:29
Abstract Reconstruction of soft‐tissue defects in the foot weight‐bearing area should encompass sensate and robust skin. Regarding forefoot defects, distally based medial plantar artery (MPA) flap is an ideal option. However, considering variation of the terminal branches of the MPA, reverse flow flaps can be unreliable with an increasing risk of venous congestion or insufficient arterial flow. In this report, we present a case of the use of reverse flow MPA flaps with dual flow vascularization....
Fri Apr 03, 2020 19:25
Abstract In the current global home confinement situation due to the COVID‐19 outbreak, most individuals are exposed to an unprecedented stressful situation of unknown duration. This may not only increase daytime stress, anxiety and depression levels but also disrupt sleep. Importantly, because of the fundamental role that sleep plays in emotion regulation, sleep disturbance can have direct consequences upon next day emotional functioning. In this paper we summarize what is known about the stress‐sleep...
Sat Apr 04, 2020 18:54
Abstract Physicians belong to the risk group for sleep disorders as a result of work related stress, excessive working time, large amount of on‐call duties and shift work. Poor sleep quality of healthcare providers threatens not only their safety, but also the safety of their patients. This study examines if there are any differences in how working either long hours or at night duties relates to self‐reported sleep time, sleep quality and daytime sleepiness in primary care physicians. We analyzed...
Fri Apr 03, 2020 18:34
Abstract Malignant mesothelioma (MM) is one of the most lethal tumors in humans. The onset of MM is linked to exposure to asbestos, which generates reactive oxygen species (ROS). ROS are believed to be derived from the frustrated phagocytosis and the iron in asbestos. To explore the pathogenesis of MM, peritoneal MM was induced in rats by the repeated intraperitoneal injection of iron saccharate and nitrilotriacetate. In this study, we employed microarray techniques to screen the microRNA (miR)...
Sat Apr 04, 2020 20:38
Abstract In Japan, the serious adverse events after HPV vaccination were widely reported in the media. The Ministry of Health, Labour and Welfare (MHLW) announced the suspension of the governmental recommendation of HPV vaccine in 2013, and the inoculation rate has sharply declined. The estimated inoculation rate for each birth fiscal year (FY) announced by the MHLW and the actual numbers for each birth FY surveyed by the local governments were far apart. Especially, the cumulative vaccination...
Sat Apr 04, 2020 20:34
Abstract Glioblastoma multiform (GBM), a lethal brain tumor developing in the white matter of the adult brain, contains a small population of GBM stem cells (GSCs), which potentially cause chemotherapeutic resistance and tumor recurrence. However, the mechanisms underlying the pathogenesis and maintenance of GSCs remain largely unknown. A recent study reported that incorporation of ribosomes and ribosomal proteins into somatic cells promoted lineage trans‐differentiation toward multipotency. This...
Sat Apr 04, 2020 20:33
Abstract In our study, we focused on possible effects of supplementation with glucan and vitamin D on total numbers of NK cells in patients with diabetic retinopathy. We evaluated possible relations among nutritional state (BMI), leptin levels, and total numbers of NK cells in patients supplemented with (1) glucan and vitamin D, (2) vitamin D and placebo, and (3) vitamin D alone. Our results show that 3 months of supplementation with both glucan and vitamin D resulted in significant...
Sat Apr 04, 2020 03:00
Presenting an integrated Neuroradiology Clinical discussion starting with evaluation of patient and discussion of the Radiological findings and treatment.Famous Radiology Blog http://www.sumerdoc.blogspot.com TeleRad Providers at www.teleradproviders.com Mail us at sales@teleradproviders.com
Sun Apr 05, 2020 09:41
22 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "Vestn Otorinolaringol"[jour] These pubmed results were generated on 2020/04/05PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sun Apr 05, 2020 07:43
Abstract Ninety percent of childhood renal tumors are Wilms tumors (nephroblastoma). While the Children’s Oncology Group (COG) recommends primary surgery, the International Society of Paediatric Oncology (SIOP) recommends neoadjuvant chemotherapy, which can be initiated without histological confirmation if the presentation is typical for Wilms tumor. This review article describes the clinical, biological and radiologic criteria used by the SIOP community to consider diagnostic...
Sun Apr 05, 2020 03:00
Abstract Interest in and awareness of bladder cancer may translate to better health-seeking behaviors and earlier detection, given modifiable risk factors such as smoking. We assessed bladder cancer interest in the USA over the past 15 years as reflected by Internet search trends, and correlated these trends with epidemiologic patterns in bladder cancer. Google Trends was used to estimate US bladder cancer interest in the unit search volume index (SVI), which estimates the volume...
Sun Apr 05, 2020 03:00
We thank Dr. Park and colleagues for their compliments and important comments on our paper “Safety and efficacy of reduced dose and margins to involved lymph node metastases in locally advanced non-small cell lung cancer patients”[1]. We reported on LA-NSCLC patients after concurrent chemoradiation and showed an improved median overall survival (OS) of 35 months in the reduction-cohort versus 26 months in the reference-cohort. It was hypothesized that the OS benefit was a reflection of an improved...
Sat Apr 04, 2020 03:00
Receiving diagnosis of cancer leads the establishment of several psychological dynamics: fear of dying, uncertainty, loss of control, change in interpersonal relationships and self-image. In this patients’ setting, the psychological structure often represents a “baggage” during their oncological treatments, which are “LIFE-SAVING” and cannot be postponed.
Sat Apr 04, 2020 03:00
We thank Kibe Y et al. for their interest in our manuscript “A mid-treatment break and reassessment maintains tumor control and reduces toxicity in patients with hepatocellular carcinoma treated with stereotactic body radiation therapy” and appreciate the opportunity to clarify our study design and analyses in response to their comments.
Fri Apr 03, 2020 03:00
We read the article entitled ‘‘Safety and efficacy of reduced dose and margins to involved lymph node metastases in locally advanced non-small cell lung cancer (NSCLC) patients” by van Diessen et al. with great interest [1]. This observational study evaluated whether mediastinal dose and margin could be safely reduced using simultaneous integrated boost and daily image guidance with carina registration. The reference-cohort received 24 × 2.75 Gy (EQD210 = 70 Gy) dose for the involved lymph nodes,...
Fri Apr 03, 2020 03:00
Oral Allergy Syndrome (OAS) is a specific type of allergic reaction that mainly occurs after the consumption of raw fruit, vegetables, and nuts.1 In adults, OAS represents the most common allergic reaction to food, affecting patients with pollen sensitization due to homology between plant proteins.2 It is a complex syndrome with diagnostic and therapeutic challenges, requiring comprehensive history taking and examination. We discuss a case of OAS following Mojo (sauce used in Cuban food) ingestion,...
Sat Apr 04, 2020 03:00
Ingredients in toothpaste may cause allergic and irritant contact stomatitis (Table I). Flavourings are most commonly incriminated, as they are present in 95% of toothpastes.1 Less frequently, cinnamon, fluoride and Anethole (Anise camphor) have been suggested to cause local irritation.2,3 Pruritis and flexural dermatitis to toothpaste has been reported in a 50-year-old woman sensitized to stannous fluoride (SnF2) on patch testing.4
Sat Apr 04, 2020 03:00
Cephalosporins are one of the most prescribed classes of antibiotics1 and 1-3% of population report a cephalosporin allergy2. They are beta-lactam antibiotics and their chemistry, mechanism of action and toxicity are similar to penicillins. The most common classification of cephalosporins is by generation. There are five generations of cephalosporins.
Sat Apr 04, 2020 03:00
The Learning Early About Peanut Allergy (LEAP) trial and other studies suggest early peanut (PN) introduction prevents PN allergy in at-risk infants.1,2 In addition, PN-oral immunotherapy (PN-OIT) shows increased rates of sustained unresponsiveness in children <5 years with known PN allergy,3 suggesting better outcomes with early exposure. The LEAP trial excluded infants with skin prick tests (SPT) >4 mm.1 Guidelines recommend PN introduction or oral food challenge (OFC) in infants who have...
Sat Apr 04, 2020 03:00
The DNA sequencing of a healthy German shepherd offers scientists new insight into the evolution of the domestic dog while also enabling dogs to be screened for hip and other diseases much more accurately.
Wed Apr 01, 2020 18:17
In the case of pandemic crisis situations, a crucial lack of protective material such as protective face masks for healthcare professionals can occur. A proof of concept (PoC) and prototype are presented, demonstrating a reusable custom-made three-dimensionally (3D) printed face mask based on materials and techniques (3D imaging and 3D printing) with global availability. The individualized 3D protective face mask consists of two 3D-printed reusable polyamide composite components (a face mask and...
Sat Apr 04, 2020 03:00
The aim of this study was to assess implant retreatment in a group of patients whose maxillary implants were all failing after full arch rehabilitation. Treatment involved implant removal, augmentation, and placement of an overdenture supported by four to six implants. All consecutive patients referred between 2008 and 2018, following multiple late implant failures in the rehabilitated maxilla, were included in the study. Seventy implants in 15 patients were evaluated at 3.3 ± 2.5 years (range 1.1–8.6...
Fri Apr 03, 2020 03:00
Hemifacial hyperplasia (HFH) is characterized by an increase in volume of all affected tissues of half of the face. It is present at birth, subsequently grows proportionally, and stops growing before adulthood. Unilateral condylar hyperplasia (UCH) consists of progressive asymmetric growth of the mandible and develops typically in early adulthood. Both disorders have an unknown aetiology. The overgrowth limited to one body part suggests somatic mosaicism, as this has been found in other similar localized...
Fri Apr 03, 2020 03:00
Abstract Purpose Ectopic parathyroid glands are thought to be the cause of a significant portion of failed primary surgery for hyperparathyroidism. Parathyroid carcinoma (PTCA) is a rare malignant tumor, and ectopic PTCA is a particularly unusual situation. Here, we describe, for the first time, a case of intrapericardial PTCA. Methods We describe...
Sat Apr 04, 2020 03:00
Abstract Purpose Oral microbiota maintains a dynamic ecological balance with the host. However, a disruption in this balance can lead to oral diseases such as dental caries and periodontitis. Several studies suggest differences in microbial composition in the oral cavity between patients with T2DM and nondiabetic patients. However, there is inadequate oral microbiome-related data from Chinese patients with T2DM, and the difference in...
Fri Apr 03, 2020 03:00
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