Related ArticlesPrimary malignant melanoma arising from ruptured ovarian mature cystic teratoma with elevated serum CA 19-9: a case report and review of literature. BMC Womens Health. 2019 11 27;19(1):149 Authors: Choi WK, Lee DH, Cho DH, Jang KY, Kim KM Abstract BACKGROUND: Ovarian mature cystic teratomas comprise tissues derived from all three germ layers. In rare incidences, malignant tumors may arise from ovarian mature cystic teratoma, which occurs...
Sat Apr 04, 2020 13:29
Related ArticlesClinical and imaging features of myeloid sarcoma: a German multicenter study. BMC Cancer. 2019 Nov 27;19(1):1150 Authors: Meyer HJ, Pönisch W, Schmidt SA, Wienbeck S, Braulke F, Schramm D, Surov A Abstract BACKGROUND: Myeloid sarcoma (MS), also known as chloroma, is an extramedullary manifestation of malignant primitive myeloid cells. Previously, only small studies investigated clinical and imaging features of MS. The purpose of this...
Sat Apr 04, 2020 13:29
Related ArticlesFirst report of pulmonary sclerosing pneomucytoma with malignant transformation in both cuboidal surface cells and stromal round cells: a case report. BMC Cancer. 2019 Nov 27;19(1):1154 Authors: Teng X, Teng X Abstract BACKGROUND: Pulmonary sclerosing pneumocytoma (PSP) is a rare benign tumor. Although lymph node metastasis has been reported, it is still considered benign. No malignant transformation has been reported. This is the first...
Sat Apr 04, 2020 13:29
Related ArticlesFrontal sinus cholesteatoma: a masquerading diagnosis. BMJ Case Rep. 2019 Nov 19;12(11): Authors: Kurien R, Thomas L, Varghese L, Nair BR Abstract Cholesteatoma of the paranasal sinus is a very rare condition. As in the tympanomastoid region where cholesteatomas are a common entity, the paranasal sinus cholesteatomas also tend to erode the surrounding bony structures. Because of the extensive bony erosion, this condition often masquerades...
Sat Apr 04, 2020 13:29
Related ArticlesNeuroendocrine tumour of urinary bladder: a rare case of aggressively behaving primary well-differentiated neuroendocrine tumour with review of literature. BMJ Case Rep. 2019 Nov 19;12(11): Authors: Dadhwal R, Jain S, Seth A, Bal CS Abstract Neuroendocrine tumour (NET) of the urinary bladder (UB) is a rare entity and comprises of well-differentiated, small cell and large cell types. Small and large cell NET like that in lung and gastrointestinal...
Sat Apr 04, 2020 13:29
Related ArticlesDiabetes insipidus and panhypopituitarism as a first presentation of silent adenocarcinoma of lung: a case report and literature review. BMC Endocr Disord. 2019 Oct 29;19(1):114 Authors: Sirinvaravong S, Vibhatavata P, Chunharojrith P, Cheunsuchon P, Sriussadaporn S Abstract BACKGROUND: Pituitary metastasis is a rare condition with a poor prognosis. Very few patients with pituitary metastasis are symptomatic. It is often associated...
Sat Apr 04, 2020 13:29
Related ArticlesTransungual Excision of Glomus Tumors: A Treatment and Quality of Life Study. Dermatol Surg. 2020 01;46(1):103-112 Authors: Reinders EFH, Klaassen KMG, Pasch MC Abstract BACKGROUND: Glomus tumors are rare benign painful tumors, frequently found in the subungual region. Complete surgical excision is essential for relief of symptoms. The main postoperative complications are tumor recurrence and nail dystrophy. OBJECTIVE: To evaluate...
Sat Apr 04, 2020 13:29
Related ArticlesImmunophenotyping of Acute Lymphoblastic Leukemia. Methods Mol Biol. 2019;2032:297-310 Authors: DiGiuseppe JA, Cardinali JL Abstract Immunophenotyping by flow cytometry is an important component in the diagnostic evaluation of patients with acute lymphoblastic leukemia. This technique further permits the detection of minimal residual disease after therapy, a robust prognostic factor that may guide individualized treatment. We describe...
Sat Apr 04, 2020 13:29
Related ArticlesRare Event Phenotyping and Molecular Characterization: Circulating Tumor Cells. Methods Mol Biol. 2019;2032:213-226 Authors: Sen M, Wang L, Yu L, Carpenter EL Abstract Noninvasive isolation of circulating tumor cells (CTCs) from patient blood samples allows for interrogation of valuable molecular and phenotypic information useful for disease diagnosis and monitoring response to therapy. However, CTCs are extremely rare relative to red...
Sat Apr 04, 2020 13:29
Related ArticlesAQP4-IgG-seropositive neuromyelitis optica spectrum disorder (NMOSD) coexisting with anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis: A case report and literature review. Mult Scler Relat Disord. 2019 Oct;35:185-192 Authors: Tao S, Zhang Y, Ye H, Guo D Abstract BACKGROUND: Neuromyelitis optica spectrum disorder (NMOSD) can coexist with anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis. Patients with overlapping Aquaporin...
Sat Apr 04, 2020 13:29
Related ArticlesA 2019 update on TSH-secreting pituitary adenomas. J Endocrinol Invest. 2019 Dec;42(12):1401-1406 Authors: Beck-Peccoz P, Giavoli C, Lania A Abstract Thyrotropin-secreting pituitary adenomas (TSH-omas) present with signs and symptoms of hyperthyroidism and they are characterized by elevated serum levels of free thyroid hormones with measurable TSH levels. TSH-omas are very infrequent, accounting for less than 1% of all pituitary adenomas,...
Sat Apr 04, 2020 13:29
Related ArticlesConcomitant EGFR Mutation and EML4-ALK Rearrangement in Lung Adenocarcinoma Is More Frequent in Multifocal Lesions. Clin Lung Cancer. 2019 07;20(4):e517-e530 Authors: Fan J, Dai X, Wang Z, Huang B, Shi H, Luo D, Zhang J, Cai W, Nie X, Hirsch FR Abstract BACKGROUND: The coexistence of epidermal growth factor receptor (EGFR) mutation and anaplastic lymphoma kinase (ALK) rearrangement in patients with multifocal lung adenocarcinomas (LUAC)...
Sat Apr 04, 2020 13:29
Related ArticlesIncreased Galectin-1 Expression in Thymic Epithelial Tumors. Clin Lung Cancer. 2019 05;20(3):e356-e361 Authors: Riess JW, Kong CS, West RB, Padda SK, Neal JW, Wakelee HA, Le QT Abstract INTRODUCTION: Thymic epithelial tumors (TET) are rare malignancies with a paucity of data on biology and therapeutics. Galectin-1 is a member of the β-galactoside binding protein family and has been shown to mediate tumor growth via modulation of immune...
Sat Apr 04, 2020 13:29
Related ArticlesImmunotherapy for LELC: Case Report and a Focused Review. Clin Lung Cancer. 2019 05;20(3):e393-e401 Authors: Darrason M, Martin A, Soussan M, Chouahnia K, Pailler MC, Boudabous H, Brillet PY, Bousquet G, Zelek L, Duchemann B Abstract Lymphoepithelioma-like carcinoma of the lung (LELC) is a rare, Epstein-Barr virus-associated tumor. LELC occurs mostly in young, Asian nonsmokers. A few hundred cases have been reported, mostly from retrospective...
Sat Apr 04, 2020 13:29
Related ArticlesClinical Features and Prognosis of Pulmonary Lymphoepithelioma-like Carcinoma: Summary of Eighty-five Cases. Clin Lung Cancer. 2019 05;20(3):e329-e337 Authors: Qin Y, Gao G, Xie X, Zhu Z, Guan W, Lin X, Xie Z, Ming O, Chen R, Zhong N, Li S, Zhou C Abstract BACKGROUND: Pulmonary lymphoepithelioma-like carcinoma (PLELC) is a rare subtype of lung cancer that is less reported and not well-understood. MATERIALS AND METHODS: We investigated...
Sat Apr 04, 2020 13:29
Related ArticlesImpact of H3.3 K27M Mutation on Prognosis and Survival of Grade IV Spinal Cord Glioma on the Basis of New 2016 World Health Organization Classification of the Central Nervous System. Neurosurgery. 2019 05 01;84(5):1072-1081 Authors: Yi S, Choi S, Shin DA, Kim DS, Choi J, Ha Y, Kim KN, Suh CO, Chang JH, Kim SH, Yoon DH Abstract BACKGROUND: Spinal cord glioma grade IV is a rare, diffuse midline glioma. H3 K27M-mutant was classified in...
Sat Apr 04, 2020 13:29
Related ArticlesAnticancer properties and mechanism of action of the quassinoid ailanthone. Phytother Res. 2020 Apr 01;: Authors: Bailly C Abstract Ailanthone (AIT) is a quassinoid natural product isolated from the worldwide-distributed plant Ailanthus altissima. The drug displays multiple pharmacological properties, in particular significant antitumor effects against a variety of cancer cell lines in vitro. Potent in vivo activities have been evidenced...
Fri Apr 03, 2020 14:20
Related ArticlesHairy Cell Leukemia and Ground Water Contamination With Industrial Solvents: a Case Report. Mil Med. 2020 Apr 01;: Authors: Green-Lott AM, Singaraju R, Liu ML, Ascensao J Abstract The industrial solvents benzene and trichloroethylene (TCE) are known carcinogens, and these solvents contaminated the drinking water at Marine Corps Base Camp Lejeune from the 1950s to 1980s. Benzene and TCE are linked to the hematopoietic cancers acute myelocytic...
Fri Apr 03, 2020 14:20
Related ArticlesBRAF V600E-mutated metastatic pediatric Wilms tumor with complete response to targeted RAF/MEK inhibition. Cold Spring Harb Mol Case Stud. 2020 Apr;6(2): Authors: Obasaju P, Shahab S, Dunn E, Rhee DS, Jiang L, Dome JS, Friedman AD, Argani P, Pratilas CA Abstract Wilms tumor (WT) is the most common renal malignancy of childhood and accounts for 6% of all childhood malignancies. With current therapies, the 5-yr overall survival (OS) for...
Fri Apr 03, 2020 14:20
Related ArticlesLetting the GENIE Out of Its Bottle: Examining the Potential of Real-World Clinicogenomic Data. Cancer Discov. 2020 Apr;10(4):490-491 Authors: Castellanos E, Baxi SS Abstract In this issue, Smyth and colleagues investigate the natural history of AKT1-mutant metastatic breast cancer using the AACR Project GENIE, a novel research platform comprised of real-world, clinicogenomic data. A rare subset of tumors, AKT1-mutant breast cancers demonstrated...
Fri Apr 03, 2020 14:20
Related Articles[Fistula surgery]. Urologe A. 2020 Mar 31;: Authors: Rosenbaum CM, Vetterlein MW, Fisch M Abstract Vesicovaginal fistulas are a rare problem in the western world but are frequent occurrences in developing countries. In Germany the most frequent cause is hysterectomy. Vesicovaginal fistulas can be treated by the transvaginal or transabdominal approach depending on the characteristics of the fistula and the patient. The incidence and complexity...
Fri Apr 03, 2020 13:20
Related ArticlesHuman Papillomavirus (HPV69/HPV73) Coinfection associated with Simultaneous Squamous Cell Carcinoma of the Anus and Presumed Lung Metastasis. Viruses. 2020 Mar 22;12(3): Authors: Shea S, Muñoz M, Ward SC, Beasley MB, Gitman MR, Nowak MD, Houldsworth J, Sordillo EM, Ramirez JD, Paniz Mondolfi AE Abstract BACKGROUND: Human papillomaviruses (HPVs) have been linked to a variety of human cancers. As the landscape of HPV-related neoplasia continues...
Fri Apr 03, 2020 13:20
Related ArticlesLandscape and Future Perspectives of Immunotherapy in Neuroendocrine Neoplasia. Cancers (Basel). 2020 Mar 30;12(4): Authors: Maggio I, Manuzzi L, Lamberti G, Ricci AD, Tober N, Campana D Abstract BACKGROUND: Neuroendocrine neoplasms are rare entities consisting of a heterogeneous group of tumors that can originate from neuroendocrine cells present in the whole body. Their different behavior, metastatic potential, and prognosis are highly...
Fri Apr 03, 2020 13:20
Related Articles[Analysis of Collision Carcinoma of Larynx Between Moderately Differentiated Squamous Cell Carcinoma and Poorly Differentiated Neuroendocrine Carcinoma from One Case]. Sichuan Da Xue Xue Bao Yi Xue Ban. 2020 Mar;51(2):261-263 Authors: Qiao YX, Zhao Y, Jiang LL Abstract A 75-year-old male patient was hospitalized in hoarseness for 2 months. Laryngoscopy showed a mass protruding in right laryngeal chamber and covering the middle part of...
Fri Apr 03, 2020 13:20
Related ArticlesAL amyloidosis in the Chilean public health system: a pending debt. Multicenter study of the Chilean Monoclonal Gammopathies Cooperative Group. Rev Med Chil. 2019 Oct;147(10):1239-1246 Authors: Peña C, González JT, López-Vidal H, Donoso J, Contreras C, Vergara CG, Hojas R, Soto P, Correa G, Valjalo R, Ríos Á, Larrondo J, Álvarez J, Rojas C Abstract BACKGROUND: Immunoglobulin light chain (AL) amyloidosis is a rare and underdiagnosed entity....
Fri Apr 03, 2020 13:20
Related ArticlesEccrine poromatosis following chemotherapy and radiation therapy. Dermatol Online J. 2019 Nov 15;25(11): Authors: Nguyen K, Kim G, Chiu M Abstract Eccrine poroma presents as a single, symptomless erythematous papule in areas with a high density of eccrine sweat glands. Although rare, eccrine poromas can present as multiple lesions, otherwise known as eccrine poromatosis. The etiology of eccrine poromatosis is unclear. We present two cases...
Fri Apr 03, 2020 13:20
Related ArticlesGorlin syndrome in a patient with skin type VI. Dermatol Online J. 2019 Nov 15;25(11): Authors: Poladian K, Difato TC, Anderson KL, Taylor SL Abstract Gorlin syndrome, also known as nevoid basal cell carcinoma syndrome, is a rare autosomal dominant disorder that is characterized by multiple basal cell carcinomas developing at a young age, keratocystic odontogenic tumors of the jaw, palmar or plantar pits, calcification of the falx cerebri,...
Fri Apr 03, 2020 13:20
Related ArticlesPleomorphic dermal sarcoma in a man with HIV: report with next-generation sequencing analysis and review of the atypical fibroxanthoma/pleomorphic dermal sarcoma spectrum. Dermatol Online J. 2019 Nov 15;25(11): Authors: Chen SX, Eichenfield DZ, Orme C, Hinds B Abstract Atypical fibroxanthoma (AFX) is a rare cutaneous fibrohistiocytic tumor that typically arises on chronically sun-damaged skin, such as the head and neck, as a nondescript...
Fri Apr 03, 2020 13:20
Related ArticlesVery high rate of false positive biochemical results when screening for pheochromocytoma in a large, undifferentiated population with variable indications for testing. Clin Biochem. 2020 Mar;77:26-31 Authors: Kline GA, Boyd J, Leung AA, Tang A, Sadrzadeh HM Abstract OBJECTIVE: Pheochromocytoma/Paraganglioma (PPGL) is a rare tumor with non-specific presentations overlapping common entities like anxiety, hypertension, acute illness and...
Fri Apr 03, 2020 13:20
Related ArticlesTreatment of consistent BRAF/HRAS gene mutation and MYC amplification radiation-induced abdominal wall angiosarcoma with low-dose apatinib: a case report. BMC Cancer. 2019 Dec 05;19(1):1188 Authors: Guan J, Luo Z, Xiao Z, Xie Y, Lin L Abstract BACKGROUND: An extremely rare condition, radiation-induced angiosarcoma is characterized by a poor prognosis, high recurrence rate and lack of effective treatment. Herein, we present a case report...
Fri Apr 03, 2020 13:20
Related ArticlesCase report of ascending colon cancer and multiple jejunal GISTs in a patient with neurofibromatosis type 1 (NF1). BMC Cancer. 2019 Dec 05;19(1):1196 Authors: Shang L, Fang Z, Liu J, Du F, Jing H, Xu Y, Dong K, Zhang X, Wu H, Jing C, Li L Abstract BACKGROUND: NF1(Neurofibromatosis type 1) is an autosomal dominant genetic disorder. Patients with NF1 have an increased risk of developing benign or malignant tumours, such as gastrointestinal...
Fri Apr 03, 2020 13:20
Related ArticlesHER2 gene (ERBB2) amplification is a rare event in non-liver-fluke associated cholangiocarcinogenesis. BMC Cancer. 2019 Dec 05;19(1):1191 Authors: Albrecht T, Rausch M, Rössler S, Albrecht M, Braun JD, Geissler V, Mehrabi A, Vogel MN, Pathil-Warth A, Mechtersheimer G, Renner M, Rupp C, Weiss KH, Busch E, Köhler B, Springfeld C, Schirmacher P, Goeppert B Abstract BACKGROUND: Cholangiocarcinoma is a rapidly fatal cancer entity with a...
Fri Apr 03, 2020 13:20
Related Articles[A case of right atrial high grade angiosarcoma presenting with pulmonary embolism and cardiac tamponade]. G Ital Cardiol (Rome). 2019 Nov;20(11):664-667 Authors: Terlizzese G, Del Re F, Pucci A, Pedrinelli R Abstract Cardiac sarcoma is the commonest histology among primary cardiac tumors but it is a rare clinical entity and it is characterized by late stage presentation, poor prognosis from the time of detection and a variety of clinical...
Fri Apr 03, 2020 13:20
Related ArticlesMolecular characterisation of genital human papillomavirus among women in Southwestern, Nigeria. PLoS One. 2019;14(11):e0224748 Authors: Nejo YT, Olaleye DO, Odaibo GN Abstract BACKGROUND: Persistent infections with high-risk genital Human papillomavirus (HPV) especially types 16 and 18, are associated with cervical cancer. However, distribution of HPV types varies greatly across geographical regions and the available vaccines target...
Fri Apr 03, 2020 13:20
Related ArticlesThe HSP90 inhibitor onalespib potentiates 177Lu‑DOTATATE therapy in neuroendocrine tumor cells. Int J Oncol. 2019 Dec;55(6):1287-1295 Authors: Lundsten S, Spiegelberg D, Stenerlöw B, Nestor M Abstract 177Lu‑DOTATATE was recently approved for the treatment of somatostatin receptor (SSTR)‑positive neuroendocrine tumors (NETs). However, despite impressive response rates, complete responses are rare. Heat shock protein 90 (HSP90) inhibitors...
Fri Apr 03, 2020 13:20
Related ArticlesClinicopathological characteristics and frequency of multiple rectal neuroendocrine tumors: a single-center retrospective study. Int J Colorectal Dis. 2019 Nov;34(11):1887-1894 Authors: Nishikawa Y, Chino A, Ide D, Saito S, Igarashi M, Takamatsu M, Fujisaki J, Igarashi Y Abstract BACKGROUND: Rectal multiple neuroendocrine tumors (M-NETs) are rare, with only few epidemiologic reports on the topic. Therefore, their clinicopathological...
Fri Apr 03, 2020 13:20
Related ArticlesPrognostic nomogram predicts overall survival in pulmonary large cell neuroendocrine carcinoma. PLoS One. 2019;14(9):e0223275 Authors: He Y, Liu H, Wang S, Chen Y Abstract BACKGROUND: Large cell neuroendocrine carcinoma (LCNEC) is a rare and typically aggressive malignancy with poor prognosis. This study developed a nomogram model to predict the overall survival (OS) of patients with LCNEC. METHODS: LCNEC patients were identified...
Fri Apr 03, 2020 13:20
Related ArticlesA very rare cause of the intra-abdominal bleeding. Turk J Gastroenterol. 2019 Sep;30(9):846-847 Authors: Yücesoy AN PMID: 31530529 [PubMed - indexed for MEDLINE]
Fri Apr 03, 2020 13:20
Related ArticlesBilateral metastases to the extraocular muscles from small cell lung carcinoma. Arq Bras Oftalmol. 2019 08 29;82(5):422-424 Authors: Crisostomo S, Cardigos J, Fernandes DH, Luís ME, Pires GN, Duarte AF, Boavida AM Abstract Bilateral orbital metastases restricted to the extraocular muscles (EOMs) are exceedingly rare. We report a case of bilateral extraocular muscle metastases from a small cell lung carcinoma and provide a review of the...
Fri Apr 03, 2020 13:20
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