Pharmaceutics, Vol. 12, Pages 567: Injectable Lipid-Based Depot Formulations: Where Do We Stand? Pharmaceutics doi: 10.3390/pharmaceutics12060567 Authors: Lisa Rahnfeld Paola Luciani The remarkable number of new molecular entities approved per year as parenteral drugs, such as biologics and complex active pharmaceutical ingredients, calls for innovative and tunable drug delivery systems. Besides making these classes of drugs available in the body, injectable depot formulations offer...
Fri Jun 19, 2020 03:00
Pharmaceutics, Vol. 12, Pages 570: Recent Advances in the Design of Topical Ophthalmic Delivery Systems in the Treatment of Ocular Surface Inflammation and Their Biopharmaceutical Evaluation Pharmaceutics doi: 10.3390/pharmaceutics12060570 Authors: Roseline Mazet Josias B. G. Yaméogo Denis Wouessidjewe Luc Choisnard Annabelle Gèze Ocular inflammation is one of the most common symptom of eye disorders and diseases. The therapeutic management of this inflammation must be rapid...
Fri Jun 19, 2020 03:00
Pharmaceutics, Vol. 12, Pages 569: Microneedle-Based Delivery: An Overview of Current Applications and Trends Pharmaceutics doi: 10.3390/pharmaceutics12060569 Authors: Antonio José Guillot Ana Sara Cordeiro Ryan F. Donnelly M. Carmen Montesinos Teresa M. Garrigues Ana Melero Microneedle arrays (MNA) are considered as one of the most promising resources to achieve systemic effects by transdermal delivery of drugs. They are designed as a minimally invasive, painless system...
Fri Jun 19, 2020 03:00
Pharmacy, Vol. 8, Pages 105: Emergency Contraception Access and Counseling in Urban Pharmacies: A Comparison between States with and without Pharmacist Prescribing Pharmacy doi: 10.3390/pharmacy8020105 Authors: Rebecca H. Stone Sally Rafie Dennia Ernest Brielle Scutt Pharmacists are often the primary source of emergency contraception (EC) access and patient information. This study aims to identify differences in pharmacist-reported EC access and counseling between states which...
Fri Jun 19, 2020 03:00
Pharmacy, Vol. 8, Pages 104: Pharmacy Education; Competency and Beyond Pharmacy doi: 10.3390/pharmacy8020104 Authors: Martin C. Henman Competency-based curricula are the dominant approach in the education of healthcare professionals around the world today [...]
Fri Jun 19, 2020 03:00
Plants, Vol. 9, Pages 775: Effects of Biostimulants on Annurca Fruit Quality and Potential Nutraceutical Compounds at Harvest and during Storage Plants doi: 10.3390/plants9060775 Authors: Giulia Graziani Alberto Ritieni Aurora Cirillo Danilo Cice Claudio Di Vaio The cultivar Annurca is an apple that is cultivated in southern Italy that undergoes a typical redding treatment and it is appreciated for organoleptic characteristics, high pulp firmness, and nutritional profile....
Sat Jun 20, 2020 03:00
Plants, Vol. 9, Pages 776: Nitric Oxide Pre-Treatment Advances Seed Germination and Alleviates Copper-Induced Photosynthetic Inhibition in Indian Mustard Plants doi: 10.3390/plants9060776 Authors: Bilal A. Rather Iqbal R. Mir Asim Masood Naser A. Anjum Nafees A. Khan This investigation tested the efficiency of nitric oxide (NO) in alleviation of Cu-induced adverse impacts on seed germination and photosynthesis in Indian mustard (Brassica juncea L.). Pre-treatment of B. juncea...
Sat Jun 20, 2020 03:00
Plants, Vol. 9, Pages 774: Flavonoids and Isoflavonoids Biosynthesis in the Model Legume Lotus japonicus; Connections to Nitrogen Metabolism and Photorespiration Plants doi: 10.3390/plants9060774 Authors: Margarita García-Calderón Carmen M. Pérez-Delgado Peter Palove-Balang Marco Betti Antonio J. Márquez Phenylpropanoid metabolism represents an important metabolic pathway from which originates a wide number of secondary metabolites derived from phenylalanine or tyrosine,...
Sat Jun 20, 2020 03:00
Plants, Vol. 9, Pages 773: MYO, a Candidate Gene for Haploid Induction in Maize Causes Male Sterility Plants doi: 10.3390/plants9060773 Authors: Kimberly Vanous Thomas Lübberstedt Rania Ibrahim Ursula K. Frei Doubled haploid technology is highly successful in maize breeding programs and is contingent on the ability of maize inducers to efficiently produce haploids. Knowledge of the genes involved in haploid induction is important for not only developing better maize inducers,...
Fri Jun 19, 2020 03:00
Plants, Vol. 9, Pages 768: A Non-Invasive Analysis of Seed Vigor by Infrared Thermography Plants doi: 10.3390/plants9060768 Authors: Liya Liu Zhongsi Wang Jing Li Xi Zhang Ruohan Wang This paper establishes robust regression models for fast and efficient estimation of seed vigor based on high-resolution infrared thermography. High seed quality is of great significance for agricultural and silvicultural purposes, and seed vigor is a crucial agent of seed quality. In this study,...
Fri Jun 19, 2020 03:00
Plants, Vol. 9, Pages 772: Cucumber Fruit Size and Shape Variations Explored from the Aspects of Morphology, Histology, and Endogenous Hormones Plants doi: 10.3390/plants9060772 Authors: Xiaoxiao Liu Yupeng Pan Ce Liu Yuanyuan Ding Xiao Wang Zhihui Cheng Huanwen Meng Fruit size and shape are important qualities and yield traits in cucumber (Cucumis sativus L.), but the factors that influence fruit size and shape remain to be explored. In this study, we investigated...
Fri Jun 19, 2020 03:00
Plants, Vol. 9, Pages 767: Transcriptome Analysis of High-NUE (T29) and Low-NUE (T13) Genotypes Identified Different Responsive Patterns Involved in Nitrogen Stress in Ramie (Boehmeria nivea (L.) Gaudich) Plants doi: 10.3390/plants9060767 Authors: Longtao Tan Gang Gao Chunming Yu Aiguo Zhu Ping Chen Kunmei Chen Jikang Chen Heping Xiong Nitrogen-use efficiency (NUE) has significant impacts on plant growth and development. NUE in plants differs substantially in physiological...
Fri Jun 19, 2020 03:00
Plants, Vol. 9, Pages 770: Geranium and Lemon Essential Oils and Their Active Compounds Downregulate Angiotensin-Converting Enzyme 2 (ACE2), a SARS-CoV-2 Spike Receptor-Binding Domain, in Epithelial Cells Plants doi: 10.3390/plants9060770 Authors: K. J. Senthil Kumar M. Gokila Vani Chung-Shuan Wang Chia-Chi Chen Yu-Chien Chen Li-Ping Lu Ching-Hsiang Huang Chien-Sing Lai Sheng-Yang Wang Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), also known as...
Fri Jun 19, 2020 03:00
Plants, Vol. 9, Pages 769: Molecular Diagnostics and Detection of Oomycetes on Fiber Crops Plants doi: 10.3390/plants9060769 Authors: Tuhong Wang Chunsheng Gao Yi Cheng Zhimin Li Jia Chen Litao Guo Jianping Xu Fiber crops are an important group of economic plants. Traditionally cultivated for fiber, fiber crops have also become sources of other materials such as food, animal feed, cosmetics and medicine. Asia and America are the two main production areas of fiber crops...
Fri Jun 19, 2020 03:00
Plants, Vol. 9, Pages 766: Involvement of Allelopathy in the Invasive Potential of Tithonia diversifolia Plants doi: 10.3390/plants9060766 Authors: Hisashi Kato-Noguchi Tithonia diversifolia (Hemsl.) A. Gray (Asteraceae) is native to Mexico and Central America. The species is spreading quickly and has naturalized in more than 70 countries. It has often been recorded as a harmful invasive plant that disturbs native plant communities. Phytotoxic chemical interactions such as allelopathy...
Fri Jun 19, 2020 03:00
Plants, Vol. 9, Pages 765: Improved Root Growth by Liming Aluminum-Sensitive Rice Cultivar or Cultivating an Aluminum-Tolerant One Does Not Enhance Fertilizer Nitrogen Recovery Efficiency in an Acid Paddy Soil Plants doi: 10.3390/plants9060765 Authors: Hao Qing Zhang Xue Qiang Zhao Yi Ling Chen Jia Lin Wang Ren Fang Shen The root is the main site of nitrogen (N) acquisition and aluminum (Al) toxicity. The objective of this study is to investigate whether liming and cultivation...
Fri Jun 19, 2020 03:00
Plants, Vol. 9, Pages 771: Application of Trichoderma harzianum, 6-pentyl-α-pyrone and Plant Biopolymer Formulations Modulate Plant Metabolism and Fruit Quality of Plum Tomatoes Plants doi: 10.3390/plants9060771 Authors: Petronia Carillo Sheridan L. Woo Ernesto Comite Christophe El-Nakhel Youssef Rouphael Giovanna Marta Fusco Assunta Borzacchiello Stefania Lanzuise Francesco Vinale Many Trichoderma are successfully used to improve agriculture productivity due...
Fri Jun 19, 2020 03:00
Publications, Vol. 8, Pages 34: An Empirical Test of the Inter-Relationships between Various Bibliometric Creative Scholarship Indicators Publications doi: 10.3390/publications8020034 Authors: Boris Forthmann Mark A. Runco Quantifying the creative quality of scholarly work is a difficult challenge, and, unsurprisingly, empirical research in this area is scarce. This investigation builds on the theoretical distinction between impact (e.g., citation counts) and creative quality (e.g.,...
Fri Jun 19, 2020 03:00
Recycling, Vol. 5, Pages 14: Potential Recovery of Biogas from Lime Waste after Juice Extraction Using Solid–Liquid Extraction Process Recycling doi: 10.3390/recycling5020014 Authors: Oluwatosin J. Ogundare David O. Olukanni A large percentage of fruit mass is left as waste after the consumption or processing of citrus fruits. The inappropriate disposal of these wastes directly leads to environmental and economic concerns. However, scientific investigations have demonstrated that...
Fri Jun 19, 2020 03:00
Religions, Vol. 11, Pages 300: Ecce Homo—Behold the Human! Reading Life-Narratives in Times of Colonial Modernity Religions doi: 10.3390/rel11060300 Authors: Nandini Bhattacharya The essay explores Bankimchandra Chatterjee’s Krishnacaritra—published in 1886—the life of a humanised god, as engaged in cross cultural dialogues with John Robert Seeley’s Ecce Homo, Natural Religion, and The Expansion of England in particular, and the broader European...
Fri Jun 19, 2020 03:00
Religions, Vol. 11, Pages 299: Ham Sok Hon, a Pioneer of Korean Cosmopolitanism Religions doi: 10.3390/rel11060299 Authors: Song-Chong Lee This paper discusses an aspect of Ham Sok Hon’s philosophy, which the author argues would reflect, and contribute to enriching, the theory of cosmopolitanism. Ham was arguably one of the 20th century’s most influential, yet controversial, thinkers and political activists—particularly in the progressive movement of modern...
Fri Jun 19, 2020 03:00
Resources, Vol. 9, Pages 75: Combining Energy Management Indicators and Life Cycle Assessment Indicators to Promote Sustainability in a Paper Production Plant Resources doi: 10.3390/resources9060075 Authors: Espinel Blanco Valencia Ochoa Duarte-Forero This paper presents the application of an energy characterization method based on the ISO 50001 standard in a dry paper production plant. This plant operates using electricity, gas, and coal as energy sources. The last two energy...
03:00
Risks, Vol. 8, Pages 66: No-Arbitrage Principle in Conic Finance Risks doi: 10.3390/risks8020066 Authors: Mehdi Vazifedan Qiji Jim Zhu In a one price economy, the Fundamental Theorem of Asset Pricing (FTAP) establishes that no-arbitrage is equivalent to the existence of an equivalent martingale measure. Such an equivalent measure can be derived as the normal unit vector of the hyperplane that separates the attainable gain subspace and the convex cone representing arbitrage opportunities....
Fri Jun 19, 2020 03:00
Safety, Vol. 6, Pages 30: Role of Passengers in Single-Vehicle Drunk-Driving Crashes: An Injury-Severity Analysis Safety doi: 10.3390/safety6020030 Authors: Abhay Lidbe Emmanuel Kofi Adanu Elsa Tedla Steven Jones Background: Drunk-driving is a major crash risk factor, and crashes resulting from this risky behavior tend to be serious and have significant economic and societal impacts. The presence of passengers and their demographics and activities can influence risky driving...
03:00
Social Sciences, Vol. 9, Pages 106: From Social Deviance to Art: Vandalism, Illicit Dumping, and the Transformation of Matter and Form Social Sciences doi: 10.3390/socsci9060106 Authors: Mark Tano Palermo In this article, assemblage art is presented to visually underscore social discourse relevant to urban vandalism and illegal dumping. The waste emergency, brought about, in part, also by illegal dumping and littering, is experienced on a daily basis across the globe in industrialized...
Fri Jun 19, 2020 03:00
Technologies, Vol. 8, Pages 35: Unsupervised Domain Adaptation in Semantic Segmentation: A Review Technologies doi: 10.3390/technologies8020035 Authors: Marco Toldo Andrea Maracani Umberto Michieli Pietro Zanuttigh The aim of this paper is to give an overview of the recent advancements in the Unsupervised Domain Adaptation (UDA) of deep networks for semantic segmentation. This task is attracting a wide interest since semantic segmentation models require a huge amount of labeled...
03:00
Toxins, Vol. 12, Pages 412: How do Uremic Toxins Affect the Endothelium? Toxins doi: 10.3390/toxins12060412 Authors: Regiane Stafim da Cunha Andressa Flores Santos Fellype Carvalho Barreto Andréa Emilia Marques Stinghen Uremic toxins can induce endothelial dysfunction in patients with chronic kidney disease (CKD). Indeed, the structure of the endothelial monolayer is damaged in CKD, and studies have shown that the uremic toxins contribute to the loss of cell–cell junctions,...
Sat Jun 20, 2020 03:00
Toxins, Vol. 12, Pages 411: Listeria monocytogenes Interferes with Host Cell Mitosis through Its Virulence Factors InlC and ActA Toxins doi: 10.3390/toxins12060411 Authors: Ana Catarina Costa Jorge Pinheiro Sandra A. Reis Didier Cabanes Sandra Sousa Listeria monocytogenes is among the best-characterized intracellular pathogens. Its virulence factors, and the way they interfere with host cells to hijack host functions and promote the establishment and dissemination of the...
Sat Jun 20, 2020 03:00
Toxins, Vol. 12, Pages 407: The Southeast Alaska Tribal Ocean Research (SEATOR) Partnership: Addressing Data Gaps in Harmful Algal Bloom Monitoring and Shellfish Safety in Southeast Alaska Toxins doi: 10.3390/toxins12060407 Authors: Harley Lanphier Kennedy Leighfield Bidlack Gribble Whitehead Many communities in Southeast Alaska harvest shellfish such as mussels and clams as an important part of a subsistence or traditional diet. Harmful algal blooms (HABs) of...
Fri Jun 19, 2020 03:00
Toxins, Vol. 12, Pages 409: Reduced Membrane-Bound Alkaline Phosphatase Does Not Affect Binding of Vip3Aa in a Heliothis virescens Resistant Colony Toxins doi: 10.3390/toxins12060409 Authors: Daniel Pinos Maissa Chakroun Anabel Millán-Leiva Juan Luis Jurat-Fuentes Denis J. Wright Patricia Hernández-Martínez Juan Ferré The Vip3Aa insecticidal protein from Bacillus thuringiensis (Bt) is produced by specific transgenic corn and cotton varieties for efficient control of...
Fri Jun 19, 2020 03:00
Toxins, Vol. 12, Pages 410: Bioactive Metabolites and Potential Mycotoxins Produced by Cordyceps Fungi: A Review of Safety Toxins doi: 10.3390/toxins12060410 Authors: Chen Sun Luo Wang Ascomycete Cordyceps fungi such as C. militaris, C. cicadae, and C. guangdongensis have been mass produced on artificial media either as food supplements or health additives while the byproducts of culture substrates are largely used as animal feed. The safety concerns associated with the...
Fri Jun 19, 2020 03:00
Toxins, Vol. 12, Pages 408: Epidemiological and Clinical Evidence for the Role of Toxins in S. Aureus Human Disease Toxins doi: 10.3390/toxins12060408 Authors: Bennett Thomsen Staphylococcus aureus asymptomatically colonizes approximately 30–50% of the population and is a leading cause of bacteremia, bone/joint infections, and skin infections in the US. S. aureus has become a major public health threat due to antibiotic resistance and an increasing number of failed vaccine...
Fri Jun 19, 2020 03:00
Toxins, Vol. 12, Pages 406: Algicidal Molecular Mechanism and Toxicological Degradation of Microcystis aeruginosa by White-Rot Fungi Toxins doi: 10.3390/toxins12060406 Authors: Guoming Zeng Pei Gao Jiale Wang Jinxi Zhang Maolan Zhang Da Sun Current research on the inhibition of Microcystis aeruginosa growth is primarily focused on algae-lysing bacteria, and few studies have investigated the inhibitory mechanisms by which fungi affect it at the molecular level. A comparative...
Fri Jun 19, 2020 03:00
Toxins, Vol. 12, Pages 405: Evaluation of the Efficacy of Mycotoxin Modifiers and Mycotoxin Binders by Using an In Vitro Rumen Model as a First Screening Tool Toxins doi: 10.3390/toxins12060405 Authors: Sandra Debevere Dian Schatzmayr Nicole Reisinger Markus Aleschko Geert Haesaert Michael Rychlik Siska Croubels Veerle Fievez Ruminal microbiota of cattle are not able to detoxify all mycotoxins. In addition, detoxification can be hampered by adverse ruminal conditions...
Fri Jun 19, 2020 03:00
TropicalMed, Vol. 5, Pages 103: Parasites, Zoonoses and War: A Themed Issue in Honor of Emeritus Professor John M. Goldsmid Tropical Medicine and Infectious Disease doi: 10.3390/tropicalmed5020103 Authors: Richard S. Bradbury This Special Issue of Tropical Medicine and Infectious Disease is dedicated to the life and work of Emeritus Professor John Marsden Goldsmid [...]
03:00
TropicalMed, Vol. 5, Pages 102: Evaluation of Malaria Diagnostic Methods as a Key for Successful Control and Elimination Programs Tropical Medicine and Infectious Disease doi: 10.3390/tropicalmed5020102 Authors: Afoma Mbanefo Nirbhay Kumar Malaria is one of the leading causes of death worldwide. According to the World Health Organization’s (WHO’s) world malaria report for 2018, there were 228 million cases and 405,000 deaths worldwide. This paper reviews and highlights...
Fri Jun 19, 2020 03:00
Vaccines, Vol. 8, Pages 329: Modulation of Anti-Tumour Immune Responses by Probiotic Bacteria Vaccines doi: 10.3390/vaccines8020329 Authors: Georgios Aindelis Katerina Chlichlia There is a growing amount of evidence to support the beneficial role of a balanced intestinal microbiota, or distinct members thereof, in the manifestation and progression of malignant tumours, not only in the gastrointestinal tract but also in distant tissues as well. Intriguingly, bacterial species have...
03:00
Vaccines, Vol. 8, Pages 325: Immunogenicity Measures of Influenza Vaccines: A Study of 1164 Registered Clinical Trials Vaccines doi: 10.3390/vaccines8020325 Authors: Alexander Domnich Ilaria Manini Donatella Panatto Giovanna Elisa Calabrò Emanuele Montomoli Influenza carries an enormous burden each year. Annual influenza vaccination is the best means of reducing this burden. To be clinically effective, influenza vaccines must be immunogenic, and several immunological assays...
Fri Jun 19, 2020 03:00
Vaccines, Vol. 8, Pages 327: Trends, Coverage and Influencing Determinants of Influenza Vaccination in the Elderly: A Population-Based National Survey in Spain (2006–2017) Vaccines doi: 10.3390/vaccines8020327 Authors: Silvia Portero de la Cruz Jesús Cebrino Influenza is a significant public health problem and the elderly are at a greater risk of contracting the disease. The vaccination coverage of the elderly is below the Spanish target of 65% for each influenza season. The aims...
Fri Jun 19, 2020 03:00
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου