Vaccines, Vol. 8, Pages 326: IFN-I Independent Antiviral Immune Response to Vesicular Stomatitis Virus Challenge in Mouse Brain Vaccines doi: 10.3390/vaccines8020326 Authors: Anurag R. Mishra Siddappa N. Byrareddy Debasis Nayak Type I interferon (IFN-I) plays a pivotal role during viral infection response in the central nervous system (CNS). The IFN-I can orchestrate and regulate most of the innate immune gene expression and myeloid cell dynamics following a noncytopathic virus...
Fri Jun 19, 2020 03:00
Vaccines, Vol. 8, Pages 328: Seroprevalence of Neutralizing Antibodies against Japanese Encephalitis Virus among Adolescents and Adults in Korea: A Prospective Multicenter Study Vaccines doi: 10.3390/vaccines8020328 Authors: Byung Ok Kwak Young Se Kwon Young Jin Hong Chung Hyun Nahm Woori Jang Young Uh Yong Gon Cho Jimyung Kim Myungshin Kim Dong Hyun Kim The immunization schedule for the Japanese encephalitis (JE) vaccine in Korea is a two-dose primary series...
Fri Jun 19, 2020 03:00
Vaccines, Vol. 8, Pages 324: The Effect of Vaccination with Live Attenuated Neethling Lumpy Skin Disease Vaccine on Milk Production and Mortality—An Analysis of 77 Dairy Farms in Israel Vaccines doi: 10.3390/vaccines8020324 Authors: Michal Morgenstern Eyal Klement Lumpy skin disease (LSD) is an economically important, arthropod borne viral disease of cattle. Vaccination by the live attenuated homologous Neethling vaccine was shown as the most efficient measure for controlling LSD....
Fri Jun 19, 2020 03:00
Vaccines, Vol. 8, Pages 322: Livestock and Poultry Production in Nepal and Current Status of Vaccine Development Vaccines doi: 10.3390/vaccines8020322 Authors: Uddab Poudel Umesh Dahal Nabin Upadhyaya Saroj Chaudhari Santosh Dhakal The livestock and poultry sectors are an integral part of Nepalese economy and lifestyle. Livestock and poultry populations have continuously been increasing in the last decade in Nepal and are likely to follow that trend as the interests in this...
Fri Jun 19, 2020 03:00
Vaccines, Vol. 8, Pages 323: Liver Stiffness Hinders Normalization of Systemic Inflammation and Endothelial Activation after Hepatitis C Virus (HCV) Eradication in HIV/HCV Coinfected Patients Vaccines doi: 10.3390/vaccines8020323 Authors: Beatriz Álvarez Clara Restrepo Marcial García María A. Navarrete-Muñoz María A. Jiménez-Sousa Laura Prieto Alfonso Cabello Sara Nistal Salvador Resino Miguel Górgolas Norma Rallón José M. Benito Systemic inflammation,...
Fri Jun 19, 2020 03:00
Vaccines, Vol. 8, Pages 320: Merit of an Ursodeoxycholic Acid Clinical Trial in COVID-19 Patients Vaccines doi: 10.3390/vaccines8020320 Authors: Subbaya Subramanian Tinen Iles Sayeed Ikramuddin Clifford J. Steer Corona Virus Disease 2019 (COVID-19) has affected over 8 million people worldwide. We underscore the potential benefits of conducting a randomized open-label unblinded clinical trial to evaluate the role of ursodeoxycholic acid (UDCA) in the treatment of COVID-19. Some...
Fri Jun 19, 2020 03:00
Vaccines, Vol. 8, Pages 321: Overcoming Tumor Resistance to Oncolyticvaccinia Virus with Anti-PD-1-Based Combination Therapy by Inducing Antitumor Immunity in the Tumor Microenvironment Vaccines doi: 10.3390/vaccines8020321 Authors: So Young Yoo Narayanasamy Badrinath Su-Nam Jeong Hyun Young Woo Jeong Heo The tumor microenvironment (TME) comprises different types of immune cells, which limit the therapeutic efficacy of most drugs. Although oncolytic virotherapy (OVT) boosts...
Fri Jun 19, 2020 03:00
Viruses, Vol. 12, Pages 669: mRNA Profile in Milk Extracellular Vesicles from Bovine Leukemia Virus-Infected Cattle Viruses doi: 10.3390/v12060669 Authors: Hinata Ishikawa Md. Matiur Rahman Marika Yamauchi Shigeo Takashima Yoshiko Wakihara Yuji O. Kamatari Kaori Shimizu Ayaka Okada Yasuo Inoshima Milk extracellular vesicles (EVs) form an excellent source of mRNAs, microRNAs (miRNAs), proteins, and lipids that represent the physiological and pathological status...
Sat Jun 20, 2020 03:00
Viruses, Vol. 12, Pages 667: Recognition of Reovirus RNAs by the Innate Immune System Viruses doi: 10.3390/v12060667 Authors: Andrew T. Abad Pranav Danthi Mammalian orthoreovirus (reovirus) is a dsRNA virus, which has long been used as a model system to study host–virus interactions. One of the earliest interactions during virus infection is the detection of the viral genomic material, and the consequent induction of an interferon (IFN) based antiviral response. Similar...
Sat Jun 20, 2020 03:00
Viruses, Vol. 12, Pages 666: Dry Panels Supporting External Quality Assessment Programs for Next Generation Sequencing-Based HIV Drug Resistance Testing Viruses doi: 10.3390/v12060666 Authors: Marc Noguera-Julian Emma R. Lee Robert W. Shafer Rami Kantor Hezhao Ji External quality assessment (EQA) is a keystone element in the validation and implementation of next generation sequencing (NGS)-based HIV drug resistance testing (DRT). Software validation and evaluation is a critical...
Sat Jun 20, 2020 03:00
Viruses, Vol. 12, Pages 668: Adeno-Associated Virus (AAV) Capsid Stability and Liposome Remodeling During Endo/Lysosomal pH Trafficking Viruses doi: 10.3390/v12060668 Authors: Bridget Lins-Austin Saajan Patel Mario Mietzsch Dewey Brooke Antonette Bennett Balasubramanian Venkatakrishnan Kim Van Vliet Adam N. Smith Joanna R. Long Robert McKenna Mark Potter Barry Byrne Sanford L. Boye Brian Bothner Regine Heilbronn Mavis Agbandje-McKenna Adeno-associated...
Sat Jun 20, 2020 03:00
Viruses, Vol. 12, Pages 665: Extracellular Vesicle Activation of Latent HIV-1 Is Driven by EV-Associated c-Src and Cellular SRC-1 via the PI3K/AKT/mTOR Pathway Viruses doi: 10.3390/v12060665 Authors: Barclay Mensah Cowen DeMarino Kim Pinto Erickson Kashanchi HIV-1 is a global health crisis that has infected more than 37 million people. Latent reservoirs throughout the body are a major hurdle when it comes to eradicating the virus. In our previous study, we...
Fri Jun 19, 2020 03:00
Viruses, Vol. 12, Pages 664: Potent and Selective Activity against Human Immunodeficiency Virus 1 (HIV-1) of Thymelaea hirsuta Extracts Viruses doi: 10.3390/v12060664 Authors: Giuseppina Sanna Silvia Madeddu Giuseppe Murgia Gabriele Serreli Michela Begala Pierluigi Caboni Alessandra Incani Gianluigi Franci Marilena Galdiero Gabriele Giliberti Historically, natural products have been the most successful source of inspiration for the development of new drugs....
Fri Jun 19, 2020 03:00
Viruses, Vol. 12, Pages 663: Phylogenetic and Geospatial Evidence of Canine Parvovirus Transmission between Wild Dogs and Domestic Dogs at the Urban Fringe in Australia Viruses doi: 10.3390/v12060663 Authors: Mark Kelman Lana Harriott Maura Carrai Emily Kwan Michael P. Ward Vanessa R. Barrs Canine parvovirus (CPV) is an important cause of disease in domestic dogs. Sporadic cases and outbreaks occur across Australia and worldwide and are associated with high morbidity and...
Fri Jun 19, 2020 03:00
Viruses, Vol. 12, Pages 659: Forced Zika Virus Infection of Culex pipiens Leads to Limited Virus Accumulation in Mosquito Saliva Viruses doi: 10.3390/v12060659 Authors: Sandra R. Abbo Chantal B. F. Vogels Tessa M. Visser Corinne Geertsema Monique M. van Oers Constantianus J. M. Koenraadt Gorben P. Pijlman Zika virus (ZIKV) is a mosquito-borne pathogen that caused a large outbreak in the Americas in 2015 and 2016. The virus is currently present in tropical areas around...
Fri Jun 19, 2020 03:00
Viruses, Vol. 12, Pages 660: A Low Fidelity Virus Shows Increased Recombination during the Removal of an Alphavirus Reporter Gene Viruses doi: 10.3390/v12060660 Authors: Tiffany F. Kautz Elizabeth Jaworski Andrew Routh Naomi L. Forrester Reporter genes for RNA viruses are well-known to be unstable due to putative RNA recombination events that excise inserted nucleic acids. RNA recombination has been demonstrated to be co-regulated with replication fidelity in alphaviruses, but...
Fri Jun 19, 2020 03:00
Viruses, Vol. 12, Pages 662: The Interplay between Adeno-Associated Virus and its Helper Viruses Viruses doi: 10.3390/v12060662 Authors: Anita F. Meier Cornel Fraefel Michael Seyffert The adeno-associated virus (AAV) is a small, nonpathogenic parvovirus, which depends on helper factors to replicate. Those helper factors can be provided by coinfecting helper viruses such as adenoviruses, herpesviruses, or papillomaviruses. We review the basic biology of AAV and its most-studied...
Fri Jun 19, 2020 03:00
Viruses, Vol. 12, Pages 661: Turnip Mosaic Virus Coat Protein Deletion Mutants Allow Defining Dispensable Protein Domains for ‘in Planta’ eVLP Formation Viruses doi: 10.3390/v12060661 Authors: Carmen Yuste-Calvo Pablo Ibort Flora Sánchez Fernando Ponz The involvement of different structural domains of the coat protein (CP) of turnip mosaic virus, a potyvirus, in establishing and/or maintaining particle assembly was analyzed through deletion mutants of the protein. In order to...
Fri Jun 19, 2020 03:00
Vision, Vol. 4, Pages 32: Effects of Oral Antihistamines on Tear Volume, Tear Stability, and Intraocular Pressure Vision doi: 10.3390/vision4020032 Authors: Brian K. Foutch Kyle A. Sandberg Edward S. Bennett Leonard L. Naeger The goal of this study was to investigate the effects of two commonly used oral antihistamines—diphenhydramine and loratadine—on tear volume, tear breakup time, and intraocular pressure. Placebo, diphenhydramine, and loratadine were...
Sat Jun 20, 2020 03:00
Water, Vol. 12, Pages 1763: Experimental Investigation on Pouring Aggregate to Plug Horizontal Tunnel with Flow Water Water doi: 10.3390/w12061763 Authors: Gailing Zhang Shuang Hui Weixin Li Wanghua Sui This paper presents an experimental investigation on the main factors that influence the effects of pouring aggregate to plug a tunnel that has been inundated by groundwater to reduce the flow velocity. Moreover, a criterion for plugging the tunnel under infiltrating water to...
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Water, Vol. 12, Pages 1762: Understanding Future Water Challenges in a Highly Regulated Indian River Basin—Modelling the Impact of Climate Change on the Hydrology of the Upper Narmada Water doi: 10.3390/w12061762 Authors: Nathan Rickards Thomas Thomas Alexandra Kaelin Helen Houghton-Carr Sharad K. Jain Prabhash K. Mishra Manish K. Nema Harry Dixon Mohammed M. Rahman Robyn Horan Alan Jenkins Gwyn Rees The Narmada river basin is a highly regulated catchment...
Sat Jun 20, 2020 03:00
Water, Vol. 12, Pages 1761: Water Resource Systems Analysis for Water Scarcity Management: The Thames Water Case Study Water doi: 10.3390/w12061761 Authors: Mark Morley Dragan Savić Optimisation tools are a practical solution to problems involving the complex and interdependent constituents of water resource systems and offer the opportunity to engage with practitioners as an integral part of the optimisation process. A multiobjective genetic algorithm is employed in conjunction with...
Sat Jun 20, 2020 03:00
Water, Vol. 12, Pages 1760: Green Infrastructure and Water: An Analysis of Global Research Water doi: 10.3390/w12061760 Authors: José Luis Caparrós-Martínez Juan Milán-García Nuria Rueda-López Jaime de Pablo-Valenciano Green infrastructure (GI) is a nature-based solution that encompasses all actions that rely on ecosystems and the services they provide to respond to various societal challenges such as climate change, food security or disaster risk. The objective of this work...
Sat Jun 20, 2020 03:00
Water, Vol. 12, Pages 1759: Modelling PAHs Transfer from Polluted Soil to Herbaceous Species in Phytoremediation Attempts Water doi: 10.3390/w12061759 Authors: Pulchérie Matsodoum Matsodoum Nguemté Ives Magloire Kengne Kengne Noumsi Guy Valérie Djumyom Djumyom Wafo Pierre François Djocgoue Adrien Wanko To address the soil–plant transfer modelling of 13 US-EPA Polycyclic Aromatic Hydrocarbons (PAHs), a mechanistic model—MM_19—has been developed...
Sat Jun 20, 2020 03:00
Water, Vol. 12, Pages 1758: Experimental Characterization of the Hydraulic Jump Profile and Velocity Distribution in a Stilling Basin Physical Model Water doi: 10.3390/w12061758 Authors: Juan Francisco Macián-Pérez Francisco José Vallés-Morán Santiago Sánchez-Gómez Marco De-Rossi-Estrada Rafael García-Bartual The study of the hydraulic jump developed in stilling basins is complex to a high degree due to the intense velocity and pressure fluctuations and the significant air...
Sat Jun 20, 2020 03:00
Water, Vol. 12, Pages 1756: A Spatially Distributed Investigation of Stream Water Temperature in a Contemporary Mixed-Land-Use Watershed Water doi: 10.3390/w12061756 Authors: Jason P. Horne Jason A. Hubbart Stream water temperature (°C) is an important physical variable that influences many biological and abiotic water quality processes. The intermingled mosaic of land-use/land-cover (LULC) types and corresponding variability in stream water temperature (Tw) processes in contemporary...
Sat Jun 20, 2020 03:00
Water, Vol. 12, Pages 1755: Phycoremediation of Landfill Leachate with Desmodesmus subspicatus: A Pre-Treatment for Reverse Osmosis Water doi: 10.3390/w12061755 Authors: Marina Kholomyeva Radek Vurm Lucia Tajnaiová Marek Šír Mariya Maslova Vladimír Kočí Reverse osmosis is widely used as one of the most effective and advanced technologies for the treatment of leachate from landfill sites. Unfortunately, high leachate contamination—above all, ammonia nitrogen—affects...
Sat Jun 20, 2020 03:00
Water, Vol. 12, Pages 1757: Variation in Runoff, Suspended Sediment Load, and Their Inter-Relationships in Response to Climate Change and Anthropogenic Activities Over the Last 60 Years: A Case Study of the Upper Fenhe River Basin, China Water doi: 10.3390/w12061757 Authors: Luan Zhang Suqing Li Zhitao Wu Xiaohui Fan Hongjian Li Qi Meng Jing Wang The variation of river runoff (Q) and suspended sediment load (S), in addition to their influential factors, is an important...
Sat Jun 20, 2020 03:00
Water, Vol. 12, Pages 1752: Improving Inter-Laboratory Reproducibility in Measurement of Biochemical Methane Potential (BMP) Water doi: 10.3390/w12061752 Authors: Sasha D. Hafner Hélène Fruteau de Laclos Konrad Koch Christof Holliger Biochemical methane potential (BMP) tests used to determine the ultimate methane yield of organic substrates are not sufficiently standardized to ensure reproducibility among laboratories. In this contribution, a standardized BMP protocol was tested...
Fri Jun 19, 2020 03:00
Water, Vol. 12, Pages 1754: Rainfall Variability and Trend Analysis of Rainfall in West Africa (Senegal, Mauritania, Burkina Faso) Water doi: 10.3390/w12061754 Authors: Nouaceur Murarescu This study concerns the West African Sahel. The Sahelian climate is characterized by a long dry season and a rainy season which starts in June and ends in September−October. This latter season is associated with the process of oceanic moisture transfer to the mainland (the West African...
Fri Jun 19, 2020 03:00
Water, Vol. 12, Pages 1750: Scarce Water Resources and Cereal Import Dependency: The Role of Integrated Water Resources Management Water doi: 10.3390/w12061750 Authors: Castro Campos Ren Loy This study globally analyzes the nonlinear relationship between cereal import dependency and total renewable water resources per capita by testing for potential thresholds in water resources. Data are from the Food and Agriculture Organization (FAO), and consider the years of 2002, 2007,...
Fri Jun 19, 2020 03:00
Water, Vol. 12, Pages 1749: Experimental, Numerical and Field Approaches to Scour Research Water doi: 10.3390/w12061749 Authors: Chiew Lai Link Scour, which represents a fascinating and complex engineering problem involving a number of physical mechanisms and interactions, has motivated a vast amount of research following different but complementary methodological approaches such as experimental, numerical, and field methods. Far from being completely understood, scour remains...
Fri Jun 19, 2020 03:00
Water, Vol. 12, Pages 1751: Assessment of Future Water Demand and Supply under IPCC Climate Change and Socio-Economic Scenarios, Using a Combination of Models in Ourika Watershed, High Atlas, Morocco Water doi: 10.3390/w12061751 Authors: Ayt Ougougdal Yacoubi Khebiza Messouli Lachir Climate change will affect the water resources system, on global and regional levels. Over the past thirty years, the High Atlas Mountains in Morocco have experienced severe droughts, which causes...
Fri Jun 19, 2020 03:00
Water, Vol. 12, Pages 1748: Using Chlorophyll a Fluorescence Imaging to Select Desiccation-Tolerant Native Moss Species for Water-Sustainable Green Roofs Water doi: 10.3390/w12061748 Authors: Ricardo Cruz de Carvalho Teresa Paço Cristina Branquinho Jorge Marques da Silva Green roofs have been more thoroughly investigated in the last few years due to the potential benefits they offer to ecosystems in urban areas (e.g., carbon sequestration, particle retention, heat island effect...
Fri Jun 19, 2020 03:00
Water, Vol. 12, Pages 1753: Indirect Impact Assessment of Pluvial Flooding in Urban Areas Using a Graph-Based Approach: The Mexico City Case Study Water doi: 10.3390/w12061753 Authors: Marcello Arosio Mario L. V. Martina Enrico Creaco Rui Figueiredo This paper presents the application of a graph-based methodology for the assessment of flood impacts in an urban context. In this methodology, exposed elements are organized as nodes on a graph, which is used to propagate impacts...
Fri Jun 19, 2020 03:00
Water, Vol. 12, Pages 1747: Kinetics and Isotherm Modeling for the Treatment of Rubber Processing Effluent Using Iron (II) Sulphate Waste as a Coagulant Water doi: 10.3390/w12061747 Authors: Rahmat Ngteni Md. Sohrab Hossain Mohd Omar Ab Kadir Ahmad Jaril Asis Zulhafiz Tajudin There is increasing concern to determine an alternative coagulant for treating industrial effluent with minimal environmental impact and operational cost. In this study, iron (II) sulphate heptahydrate...
Fri Jun 19, 2020 03:00
Water, Vol. 12, Pages 1746: Water Supply Delivery Failures—A Scenario-Based Approach to Assess Economic Losses and Risk Reduction Options Water doi: 10.3390/w12061746 Authors: Karin Sjöstrand Andreas Lindhe Tore Söderqvist Lars Rosén Access to a reliable water supply is central for a well-functioning society. However, water supply systems are subject to a wide range of threats which may affect their ability to provide water to society. This paper presents a novel risk assessment...
Fri Jun 19, 2020 03:00
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