Nature Communications, Published online: 10 March 2020; doi:10.1038/s41467-020-15061-xSynthetic RNA-based circuits allow for gene regulation without the risk of mutagenesis. Here the authors demonstrate a Caliciviral VPg-based Translational activator which allows translational activation of synthetic mRNAs.
Nature Communications, Published online: 10 March 2020; doi:10.1038/s41467-020-14850-8In infants, superiority of semantic over episodic memory formation has been postulated. Here, authors show that both types of memory coexist in one-year-olds, with consolidation during sleep affecting whether an experienced event is recognized as a detailed episode or as general semantic knowledge.
Nature Communications, Published online: 10 March 2020; doi:10.1038/s41467-020-14336-7Cell surface proteins mediate the interactions between cells and their extracellular environment. Here the authors design synthetic biomemetic receptor-like sensors that facilitate programmable interactions between bacteria and their target.
Nature Communications, Published online: 10 March 2020; doi:10.1038/s41467-020-15074-6Resolving the kinetics of energy dissipation during photosynthesis is challenging due to complex photophysics and the coexistence of multiple antenna proteins. Here Son et al. overcome this by applying ultrabroadband 2D spectroscopy to LHCII reconstituted in lipid nanodiscs, revealing mechanisms of dissipation enhanced by the membrane.
Nature Communications, Published online: 10 March 2020; doi:10.1038/s41467-020-14968-9Non-canonical HLA-bound peptides from presumed non-coding regions are potential targets for cancer immunotherapy, but their discovery remains challenging. Here, the authors integrate exome sequencing, transcriptomics, ribosome profiling, and immunopeptidomics to identify tumor-specific non-canonical HLA-bound peptides.
Nature Communications, Published online: 10 March 2020; doi:10.1038/s41467-020-15033-1Nature has developed the ability to produce a wide range of optical effects most notably in the butterfly wing. Here, the authors report on the analysis of the structures responsible for ultra-black coloration across different butterflies and combine this with modelling to identify the key characteristics
Nature Communications, Published online: 10 March 2020; doi:10.1038/s41467-020-15049-7The authors here analyse the petrology of the meteorite NWA 8321 (parent body Vesta). They find sulfidation processes of olivine suggesting metasomatism in the Vestan interior and a partial melting origin for the host noritic diogenite.
Nature Communications, Published online: 10 March 2020; doi:10.1038/s41467-020-14964-zAuthor Correction: Single cell transcriptome analysis of developing arcuate nucleus neurons uncovers their key developmental regulators
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Related Articles[WGCNA screening of prognostic markers in medulloblastoma]. Zhonghua Yi Xue Za Zhi. 2020 Feb 18;100(6):460-464 Authors: Du BS, Yuan L, Sun LG, Zhang ZY Abstract Objective: In this study, we used the Weighted gene co-expression network analysis (WGCNA) analysis to find the gene module that are specifically expressed in Medulloblastoma and screened the marker genes that may diagnose and treat Medulloblastoma. Methods: WGCNA was used to...
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Related ArticlesNeonatal Hypocalcemic Seizures in Offspring of a Mother with Familial Hypocalciuric Hypercalcemia Type 1 (FHH1). J Clin Endocrinol Metab. 2020 Mar 09;: Authors: Dharmaraj P, Gorvin CM, Soni A, Nelhans ND, Olesen MK, Boon H, Cranston T, Thakker RV, Hannan FM Abstract CONTEXT: Familial hypocalciuric hypercalcemia type 1 (FHH1) is caused by loss-of-function mutations of the calcium-sensing receptor (CaSR), and considered to be a benign condition...
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Publication date: Available online 9 March 2020Source: Pathology - Research and PracticeAuthor(s): Renhui Yi, Shaochun Yang, Yuanyuan Liao, Zheng Hu, Hao Long, Yu Zeng, Xizhao Wang, Chuanzhen Qiu, Anqi Xu, Jie Lin, Zhiyong Wu
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Related ArticlesRecent advances in β-lactam derivatives as potential anticancer agents. Curr Top Med Chem. 2020 Mar 09;: Authors: Zhang X, Jia Y Abstract Cancer, accounts for around 10 million deaths annually, is the second leading cause of death globally. The the continuous emergency of drug-resistant cancers and the low specificity of anticancer agents are the main challenges in the control and eradication of cancers, so it's imperative to develop...
Related ArticlesOrganic polymer and metal nano-particle based composites for improvement of analytic performance of electrochemical biosensors. Curr Top Med Chem. 2020 Mar 08;: Authors: Pundir CS, Mohan H, Kaur M, Ravina, Brar B, Shafiq M, Prasad M Abstract Metal nano-particles are described in nano scale and made from either pure metals or their compounds such as oxides. Metallic nano-particles have certain indistinct functional group due to which these...
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Related ArticlesFetal Biparietal Diameter as a Potential Risk Factor for Emergency Cesarean Section due to Labor Arrest. Tohoku J Exp Med. 2020;250(3):161-166 Authors: Shinohara S, Amemiya A, Takizawa M Abstract Labor arrest is the most common indication for emergency cesarean section (ECS). Increased biparietal diameter (BPD) has been reported as a risk factor for ECS due to labor arrest in different countries, but it is unclear whether this relationship...
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Related ArticlesFalse-Positive Cholesteatomas on Non-Echoplanar Diffusion-Weighted Magnetic Resonance Imaging. Otol Neurotol. 2020 Mar 06;: Authors: Muhonen EG, Mahboubi H, Moshtaghi O, Sahyouni R, Ghavami Y, Maducdoc M, Lin HW, Djalilian HR Abstract OBJECTIVES: To investigate false-positive findings on non-echoplanar (non-EPI) diffusion-weighted magnetic resonance imaging (DWI) in patients under surveillance post-cholesteatoma surgery. STUDY...
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Related ArticlesDecompression of Cavernous Sinus for Trigeminal Neuropathic Pain From Perineural Spread of Tumor: 2-Dimensional Operative Video. Oper Neurosurg (Hagerstown). 2020 Mar 06;: Authors: Morris TW, Hundley KN, Thomas KO, Lockhart EC, Rodriguez A, Day JD Abstract Head and neck malignancies with perineural spread are rare. Patients can present with neuropathic pain and cranial nerve palsies.1 Skull base approaches for surgical decompression are...
Related ArticlesOrbitomeningeal Band in Transcavernous Dissection and Anterior Clinoidectomy: 3-Dimensional Operative Video. Oper Neurosurg (Hagerstown). 2020 Mar 06;: Authors: Campero A, Baldoncini M, Villalonga JF, Sáenz A Abstract The orbitomeningeal or meningo-orbital band (MOB) has been described as the most superficial dural band responsible for tethering the frontotemporal basal dura to the periorbita.1,2 The MBO usually interferes with the surgical...
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