IJERPH, Vol. 17, Pages 1791: Housing Needs of Ageing Veterans Who Have Experienced Limb Loss International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17051791 Authors: Gemma Wilson Gill McGill Alison Osborne Matthew D. Kiernan Military veterans can experience limb loss as a direct result of conflict, an accident, illness or injury. Whatever the cause, there is a need to recognise the long-term consequences and challenges of limb loss on maintaining...
Tue Mar 10, 2020 02:00
IJERPH, Vol. 17, Pages 1789: Recommendations for 24-Hour Movement Behaviours in Adults with Asthma: A Review of Current Guidelines International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17051789 Authors: Shilpa Dogra Ilana Patlan Carley O’Neill Hayley Lewthwaite Background: Many countries have clinical practice guidelines (CPG) for asthma that serve as an important resource for healthcare professionals and inform the development of policies and...
Tue Mar 10, 2020 02:00
IJERPH, Vol. 17, Pages 1788: Incidence of Post-Vasectomy Pain: Systematic Review and Meta-Analysis International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17051788 Authors: Austin B. Auyeung Anas Almejally Fahad Alsaggar Frank Doyle This is the first systematic review and meta-analysis to ascertain incidences of post-vasectomy pain following traditional scalpel, or non-scalpel vasectomy. Electronic databases PubMed, Embase and PsycINFO were searched...
Tue Mar 10, 2020 02:00
IJERPH, Vol. 17, Pages 1787: Factors that Influence Chinese Parents’ Intentions to Use Physical Violence to Discipline Their Preschool Children International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17051787 Authors: Haixue Wang Guangrong Zhu Jingqi Chen Linjing Lyu Michael Dunne This study explored factors affecting parents’ intentions to use physical violence (PV) to discipline their children in the future. The theory of planned behavior...
Tue Mar 10, 2020 02:00
IJMS, Vol. 21, Pages 1904: Identification and Functional Study of Chitin Metabolism and Detoxification-Related Genes in Glyphodes pyloalis Walker (Lepidoptera: Pyralidae) Based on Transcriptome Analysis International Journal of Molecular Sciences doi: 10.3390/ijms21051904 Authors: Zuo-min Shao Yi-jiangcheng Li Xiao-rui Zhang Jie Chu Jia-hui Ma Zhi-xiang Liu Jun Wang Sheng Sheng Fu-an Wu Glyphodes pyloalis Walker (Lepidoptera: Pyralididae) is a serious pest in...
Tue Mar 10, 2020 02:00
IJMS, Vol. 21, Pages 1902: Gene Polymorphisms in Boar Spermatozoa and Their Associations with Post-Thaw Semen Quality International Journal of Molecular Sciences doi: 10.3390/ijms21051902 Authors: Anna Mańkowska Paweł Brym Łukasz Paukszto Jan P. Jastrzębski Leyland Fraser Genetic markers have been used to assess the freezability of semen. With the advancement in molecular genetic techniques, it is possible to assess the relationships between sperm functions and gene polymorphisms....
Tue Mar 10, 2020 02:00
IJMS, Vol. 21, Pages 1903: Exposure to Dichlorodiphenyldichloroethylene (DDE) and Metallothionein Levels in Rats Fed with Normocaloric or High-Fat Diet: A Review International Journal of Molecular Sciences doi: 10.3390/ijms21051903 Authors: Vincenzo Migliaccio Lillà Lionetti Rosalba Putti Rosaria Scudiero The growing number of studies on metallothioneins (MTs), cysteine-rich metal-binding proteins, have been disclosing new functions of these proteins. Thanks to their inducibility,...
Tue Mar 10, 2020 02:00
IJMS, Vol. 21, Pages 1898: Melatonin Priming Alleviates Aging-Induced Germination Inhibition by Regulating β-oxidation, Protein Translation, and Antioxidant Metabolism in Oat (Avena sativa L.) Seeds International Journal of Molecular Sciences doi: 10.3390/ijms21051898 Authors: Huifang Yan Shangang Jia Peisheng Mao Although melatonin has been reported to play an important role in regulating metabolic events under adverse stresses, its underlying mechanisms on germination in aged...
Tue Mar 10, 2020 02:00
IJMS, Vol. 21, Pages 1901: Primary Human Chondrocytes Affected by Cigarette Smoke—Therapeutic Challenges International Journal of Molecular Sciences doi: 10.3390/ijms21051901 Authors: Chen Ehnert Tendulkar Zhu Arnscheidt Aspera-Werz Nussler Although several researchers have attested deleterious effects of smoking to the musculoskeletal system, the association between smoking and the onset of osteoarthritis (OA) remains unclear. Here, we investigate the effect...
Tue Mar 10, 2020 02:00
IJMS, Vol. 21, Pages 1893: Valine Radiolysis by H+, He+, N+, and S15+ MeV Ions International Journal of Molecular Sciences doi: 10.3390/ijms21051893 Authors: Cíntia A. P. da Costa Gabriel S. Vignoli Muniz Philippe Boduch Hermann Rothard Enio F. da Silveira Radiolysis of biomolecules by fast ions has interest in medical applications and astrobiology. The radiolysis of solid D-valine (0.2–2 μm thick) was performed at room temperature by 1.5 MeV H+, He+, N+,...
Tue Mar 10, 2020 02:00
IJMS, Vol. 21, Pages 1900: Cockle Shell-Derived Aragonite CaCO3 Nanoparticles for Co-Delivery of Doxorubicin and Thymoquinone Eliminates Cancer Stem Cells International Journal of Molecular Sciences doi: 10.3390/ijms21051900 Authors: Ibiyeye Zuki Cancer stem cells CSCs (tumour-initiating cells) are responsible for cancer metastasis and recurrence associated with resistance to conventional chemotherapy. This study generated MBA MD231 3D cancer stem cells enriched spheroids in serum-free...
Tue Mar 10, 2020 02:00
IJMS, Vol. 21, Pages 1897: Pravastatin Alleviates Radiation Proctitis by Regulating Thrombomodulin in Irradiated Endothelial Cells International Journal of Molecular Sciences doi: 10.3390/ijms21051897 Authors: Jang Kwak Park Kim Kim Na Kim Jang Lee Kim Myung Shim Although radiotherapy plays a crucial in the management of pelvic tumors, its toxicity on surrounding healthy tissues such as the small intestine, colon, and rectum is one of the...
Tue Mar 10, 2020 02:00
IJMS, Vol. 21, Pages 1895: Biopolymer-Based Microcarriers for Three-Dimensional Cell Culture and Engineered Tissue Formation International Journal of Molecular Sciences doi: 10.3390/ijms21051895 Authors: Lixia Huang Ahmed M.E. Abdalla Lin Xiao Guang Yang The concept of three-dimensional (3D) cell culture has been proposed to maintain cellular morphology and function as in vivo. Among different approaches for 3D cell culture, microcarrier technology provides a promising tool...
Tue Mar 10, 2020 02:00
IJMS, Vol. 21, Pages 1879: Major Latex Protein MdMLP423 Negatively Regulates Defense against Fungal Infections in Apple International Journal of Molecular Sciences doi: 10.3390/ijms21051879 Authors: Shanshan He Gaopeng Yuan Shuxun Bian Xiaolei Han Kai Liu Peihua Cong Caixia Zhang Major latex proteins (MLPs) play critical roles in plants defense and stress responses. However, the roles of MLPs from apple (Malus × domestica) have not been clearly identified....
Tue Mar 10, 2020 02:00
IJMS, Vol. 21, Pages 1894: The Polymorphic PolyQ Tail Protein of the Mediator Complex, Med15, Regulates the Variable Response to Diverse Stresses International Journal of Molecular Sciences doi: 10.3390/ijms21051894 Authors: Jennifer E.G. Gallagher Suk Lan Ser Michael C. Ayers Casey Nassif Amaury Pupo The Mediator is composed of multiple subunits conserved from yeast to humans and plays a central role in transcription. The tail components are not required for basal transcription...
Tue Mar 10, 2020 02:00
IJMS, Vol. 21, Pages 1899: Functional Consequences of Low Activity of Transport System A for Neutral Amino Acids in Human Bone Marrow Mesenchymal Stem Cells International Journal of Molecular Sciences doi: 10.3390/ijms21051899 Authors: Martina Chiu Giuseppe Taurino Massimiliano G. Bianchi Erica Dander Alessandra Fallati Nicola Giuliani Giovanna D’Amico Ovidio Bussolati In cultured human fibroblasts, SNAT transporters (System A) account for the accumulation of non-essential...
Tue Mar 10, 2020 02:00
IJMS, Vol. 21, Pages 1892: Malignancy Grade-Dependent Mapping of Metabolic Landscapes in Human Urothelial Bladder Cancer: Identification of Novel, Diagnostic, and Druggable Biomarkers International Journal of Molecular Sciences doi: 10.3390/ijms21051892 Authors: Aikaterini Iliou Aristeidis Panagiotakis Aikaterini F. Giannopoulou Dimitra Benaki Mariangela Kosmopoulou Athanassios D. Velentzas Ourania E. Tsitsilonis Issidora S. Papassideri Gerassimos E. Voutsinas Eumorphia...
Tue Mar 10, 2020 02:00
IJMS, Vol. 21, Pages 1891: Epigenetic Regulation of WNT3A Enhancer during Regeneration of Injured Cortical Neurons International Journal of Molecular Sciences doi: 10.3390/ijms21051891 Authors: Chu-Yuan Chang Jui-Hung Hung Liang-Wei Huang Joye Li Ka Shing Fung Cheng-Fu Kao Linyi Chen Traumatic brain injury is known to reprogram the epigenome. Chromatin immunoprecipitation-sequencing of histone H3 lysine 27 acetylation (H3K27ac) and tri-methylation of histone H3 at lysine...
Tue Mar 10, 2020 02:00
IJMS, Vol. 21, Pages 1890: Leucine-Rich Repeat Kinase 2 Controls Inflammatory Cytokines Production through NF-κB Phosphorylation and Antigen Presentation in Bone Marrow-Derived Dendritic Cells International Journal of Molecular Sciences doi: 10.3390/ijms21051890 Authors: Makoto Kubo Ryuichi Nagashima Mitsue Kurihara Fumitaka Kawakami Tatsunori Maekawa Koji Eshima Etsuro Ohta Hirotomo Kato Fumiya Obata Leucine-rich repeat kinase 2 (LRRK2) is the causal molecule...
Tue Mar 10, 2020 02:00
IJMS, Vol. 21, Pages 1896: Improvement of Alcohol-Poisoning Symptoms in Mice by the Oral Administration of Live Lactobacillus plantarum SN13T Cells International Journal of Molecular Sciences doi: 10.3390/ijms21051896 Authors: Masafumi Noda Masafumi Maruyama Narandalai Danshiitsoodol Fumiko Higashikawa Masanori Sugiyama A clinical study carried out previously by our group has demonstrated that yogurt manufactured with a plant-derived lactic acid bacterium, Lactobacillus plantarum...
Tue Mar 10, 2020 02:00
IJMS, Vol. 21, Pages 1888: Effects of Osiris9a on Silk Properties in Bombyx mori Determined by Transgenic Overexpression International Journal of Molecular Sciences doi: 10.3390/ijms21051888 Authors: Tingcai Cheng Xia Zhang Zhangchuan Peng Yinfeng Fan Lin Zhang Chun Liu Osiris is an insect-specific gene family with multiple biological roles in development, phenotypic polymorphism, and protection. In the silkworm, we have previously identified twenty-five Osiris genes with...
Tue Mar 10, 2020 02:00
IJMS, Vol. 21, Pages 1887: Altered Structural Expression and Enzymatic Activity Parameters in Quiescent Ulcerative Colitis: Are These Potential Normalization Criteria? International Journal of Molecular Sciences doi: 10.3390/ijms21051887 Authors: Sebastian Kjærgaard Morten M. B. Damm Joan Chang Lene B. Riis Hanne B. Rasmussen Rasmus Hytting-Andreasen Susanne M. Krug Jörg-Dieter Schulzke Niels Bindslev Mark Berner-Hansen Mucosal healing determined by endoscopy...
Tue Mar 10, 2020 02:00
IJMS, Vol. 21, Pages 1886: At-Hook Motif Nuclear Localised Protein 18 as a Novel Modulator of Root System Architecture International Journal of Molecular Sciences doi: 10.3390/ijms21051886 Authors: Marek Širl Tereza Šnajdrová Dolores Gutiérrez-Alanís Joseph G. Dubrovsky Jean Phillipe Vielle-Calzada Ivan Kulich Aleš Soukup The At-Hook Motif Nuclear Localized Protein (AHL) gene family encodes embryophyte-specific nuclear proteins with DNA binding activity. They modulate...
Tue Mar 10, 2020 02:00
IJMS, Vol. 21, Pages 1889: HSP Transcript and Protein Accumulation in Brassinosteroid Barley Mutants Acclimated to Low and High Temperatures International Journal of Molecular Sciences doi: 10.3390/ijms21051889 Authors: Sadura Libik-Konieczny Jurczyk Gruszka Janeczko In temperature stress, the main role of heat-shock proteins (HSP) is to act as molecular chaperones for other cellular proteins. However, knowledge about the hormonal regulation of the production of the...
Tue Mar 10, 2020 02:00
IJMS, Vol. 21, Pages 1885: Promoting Roles of Embryonic Signals in Embryo Implantation and Placentation in Cooperation with Endocrine and Immune Systems International Journal of Molecular Sciences doi: 10.3390/ijms21051885 Authors: Hiroshi Fujiwara Masanori Ono Yukiyasu Sato Kazuhiko Imakawa Takashi Iizuka Kyosuke Kagami Tomoko Fujiwara Akihito Horie Hirohiko Tani Akira Hattori Takiko Daikoku Yoshihiko Araki Embryo implantation in the uterus is an essential...
Tue Mar 10, 2020 02:00
IJMS, Vol. 21, Pages 1884: Crosstalk Among Circadian Rhythm, Obesity and Allergy International Journal of Molecular Sciences doi: 10.3390/ijms21051884 Authors: Kanami Orihara Atsushi Haraguchi Shigenobu Shibata The circadian clock system works not only as a cellular time-keeper but also as a coordinator for almost all physiological functions essential to maintaining human health. Therefore, disruptions or malfunctions of this system can cause many diseases and pre-symptomatic conditions....
Tue Mar 10, 2020 02:00
IJMS, Vol. 21, Pages 1883: Bacteriophage-Insensitive Mutants of Antimicrobial-Resistant Salmonella Enterica are Altered in their Tetracycline Resistance and Virulence in Caco-2 Intestinal Cells International Journal of Molecular Sciences doi: 10.3390/ijms21051883 Authors: Karen Fong Kaiwen Mu Jean-Guillaume Rheault Roger C. Levesque David D. Kitts Pascal Delaquis Lawrence Goodridge Siyun Wang Bacteriophages have shown promise as therapeutic alternatives to antibiotics...
Tue Mar 10, 2020 02:00
IJMS, Vol. 21, Pages 1882: The mito-QC Reporter for Quantitative Mitophagy Assessment in Primary Retinal Ganglion Cells and Experimental Glaucoma Models International Journal of Molecular Sciences doi: 10.3390/ijms21051882 Authors: Ines Rosignol Beatriz Villarejo-Zori Petra Teresak Elena Sierra-Filardi Xandra Pereiro Natalia Rodríguez-Muela Elena Vecino Helena L. A. Vieira Katharina Bell Patricia Boya Mitochondrial damage plays a prominent role in glaucoma....
Tue Mar 10, 2020 02:00
IJMS, Vol. 21, Pages 1881: Flavodoxins as Novel Therapeutic Targets against Helicobacter pylori and Other Gastric Pathogens International Journal of Molecular Sciences doi: 10.3390/ijms21051881 Authors: Sandra Salillas Javier Sancho Flavodoxins are small soluble electron transfer proteins widely present in bacteria and absent in vertebrates. Flavodoxins participate in different metabolic pathways and, in some bacteria, they have been shown to be essential proteins representing promising...
Tue Mar 10, 2020 02:00
IJMS, Vol. 21, Pages 1880: Deciphering the Role of Multiple Thioredoxin Fold Proteins of Leptospirillum sp. in Oxidative Stress Tolerance International Journal of Molecular Sciences doi: 10.3390/ijms21051880 Authors: Daniela González Pamela Álamos Matías Rivero Omar Orellana Javiera Norambuena Renato Chávez Gloria Levicán Thioredoxin fold proteins (TFPs) form a family of diverse proteins involved in thiol/disulfide exchange in cells from all domains of life. Leptospirillum...
Tue Mar 10, 2020 02:00
JCDD, Vol. 7, Pages 9: Translating Translation to Mechanisms of Cardiac Hypertrophy Journal of Cardiovascular Development and Disease doi: 10.3390/jcdd7010009 Authors: Michael J. Zeitz James W. Smyth Cardiac hypertrophy in response to chronic pathological stress is a common feature occurring with many forms of heart disease. This pathological hypertrophic growth increases the risk for arrhythmias and subsequent heart failure. While several factors promoting cardiac hypertrophy are...
Tue Mar 10, 2020 02:00
JCM, Vol. 9, Pages 752: Quantitative Assessment of Gait Characteristics in Degenerative Cervical Myelopathy: A Prospective Clinical Study Journal of Clinical Medicine doi: 10.3390/jcm9030752 Authors: Kalsi-Ryan Rienmueller Riehm Chan Jin Martin Badhiwala Akbar Massicotte Fehlings It is challenging to discriminate the early presentation of Degenerative Cervical Myelopathy (DCM) as well as sensitively and accurately distinguishing between mild, moderate,...
Tue Mar 10, 2020 02:00
JCM, Vol. 9, Pages 751: Targeted Exome Sequencing Provided Comprehensive Genetic Diagnosis of Congenital Anomalies of the Kidney and Urinary Tract Journal of Clinical Medicine doi: 10.3390/jcm9030751 Authors: Yo Han Ahn Chung Lee Nayoung K. D. Kim Eujin Park Hee Gyung Kang Il-Soo Ha Woong-Yang Park Hae Il Cheong Congenital anomalies of the kidney and urinary tract (CAKUT) are the most common cause of chronic kidney disease in children. The search for genetic causes...
Tue Mar 10, 2020 02:00
JCM, Vol. 9, Pages 750: Prospective Evaluation of Intensity of Symptoms, Therapeutic Procedures and Treatment in Palliative Care Patients in Nursing Homes Journal of Clinical Medicine doi: 10.3390/jcm9030750 Authors: Daniel Puente-Fernández Concepción B Roldán-López Concepción P Campos-Calderón Cesar Hueso-Montoro María P García-Caro Rafael Montoya-Juarez The aim of the study is to evaluate the intensity of symptoms, and any treatment and therapeutic procedures received...
Tue Mar 10, 2020 02:00
JCM, Vol. 9, Pages 749: Artificial Intelligence-Based Mitosis Detection in Breast Cancer Histopathology Images Using Faster R-CNN and Deep CNNs Journal of Clinical Medicine doi: 10.3390/jcm9030749 Authors: Tahir Mahmood Muhammad Arsalan Muhammad Owais Min Beom Lee Kang Ryoung Park Breast cancer is the leading cause of mortality in women. Early diagnosis of breast cancer can reduce the mortality rate. In the diagnosis, the mitotic cell count is an important biomarker for predicting...
Tue Mar 10, 2020 02:00
JCM, Vol. 9, Pages 746: Therapeutic Applications of Curcumin Nanomedicine Formulations in Cardiovascular Diseases Journal of Clinical Medicine doi: 10.3390/jcm9030746 Authors: Bahare Salehi María L. Del Prado-Audelo Hernán Cortés Gerardo Leyva-Gómez Zorica Stojanović-Radić Yengkhom Disco Singh Jayanta Kumar Patra Gitishree Das Natália Martins Miquel Martorell Marzieh Sharifi-Rad William C. Cho Javad Sharifi-Rad Cardiovascular diseases (CVD) compromises...
Tue Mar 10, 2020 02:00
JCM, Vol. 9, Pages 747: Breast-Specific Gamma Imaging with [99mTc]Tc-Sestamibi: An In Vivo Analysis for Early Identification of Breast Cancer Lesions Expressing Bone Biomarkers Journal of Clinical Medicine doi: 10.3390/jcm9030747 Authors: Nicoletta Urbano Manuel Scimeca Carmela Di Russo Elena Bonanno Orazio Schillaci The main purpose of this pilot investigation was to evaluate the possible relationship among [99mTc]Tc-Sestamibi uptake, the presence of breast osteoblast-like...
Tue Mar 10, 2020 02:00
JCM, Vol. 9, Pages 748: Impact of Neoadjuvant Chemotherapy on the Outcomes of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Colorectal Peritoneal Metastases: A Multi-Institutional Retrospective Review Journal of Clinical Medicine doi: 10.3390/jcm9030748 Authors: Eliza W. Beal Lorena P. Suarez-Kelly Charles W. Kimbrough Fabian M. Johnston Jonathan Greer Daniel E. Abbott Courtney Pokrzywa Mustafa Raoof Byrne Lee Travis E. Grotz Jennifer...
Tue Mar 10, 2020 02:00
JCM, Vol. 9, Pages 745: Enhanced Inflammation and Nitrosative Stress in the Saliva and Plasma of Patients with Plaque Psoriasis Journal of Clinical Medicine doi: 10.3390/jcm9030745 Authors: Anna Skutnik-Radziszewska Mateusz Maciejczyk Iwona Flisiak Julita Krahel Urszula Kołodziej Anna Kotowska-Rodziewicz Anna Klimiuk Anna Zalewska Psoriasis is the most common inflammatory skin disease, characterized by the release ofproinflammatory cytokines from lymphocytes, keratinocytes,...
Tue Mar 10, 2020 02:00
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