Τρίτη 10 Μαρτίου 2020


Cervical cancer burden in Latin America and the Caribbean: Where are we?
In May 2018, the World Health Organization (WHO) called for the elimination of cervical cancer. To monitor this Initiative, we examined cervical cancer incidence and mortality in the Latin America and Caribbean (LAC) region using GLOBOCAN 2018, Cancer Incidence in Five Continents Series, and the World Health Organization Mortality Database. We estimated the number of cases and age‐standardized rates (ASRs) for cervical cancer incidence and mortality for 2018. We also presented the ASRs for recorded...
International Journal of Cancer
Tue Mar 10, 2020 09:14
Effects of Hypertonic Saline and Hydroxyethyl Starch on Myeloid-Derived Suppressor Cells in Hemorrhagic Shock Mice under Secondary Bacterial Attack
Objectives. The primary target is to reveal whether the resuscitation with hypertonic saline (HTS) or hydroxyethyl starch (HES) would have different effects on the myeloid-derived suppressor cell (MDSC) count and monocytic MDSC (M-MDSC)/granulocytic/neutrophilic MDSC (G-MDSC) rate in the peripheral blood, spleen, and bone marrow nucleated cells (BMNC) in a controlled hemorrhagic shock mouse model under secondary Escherichia coli bacterial infection attack, comparing to resuscitation with normal saline...
BioMed Research International
Tue Mar 10, 2020 09:05
Sinapic Acid Ameliorates Oxidative Stress, Inflammation, and Apoptosis in Acute Doxorubicin-Induced Cardiotoxicity via the NF-κB-Mediated Pathway
In the present study, we explored SA’s activity against DOX-induced cardiotoxicity and revealed its underlying mechanisms. Male Wistar rats (weight, 190-210g; ) were randomly divided into four groups: group I, normal control; group II, DOX 15 mg/kg via intraperitoneal (ip) route; group III, administered DOX+SA 20 mg/kg; and group IV, administered DOX+captopril (CAP 30 mg/kg). SA and CAP were administered orally for seven days, and DOX (15 mg/kg) was injected intraperitoneally an hour before SA treatment...
BioMed Research International
Tue Mar 10, 2020 09:05
Time to Development of Anemia and Predictors among HIV-Infected Patients Initiating ART at Felege Hiwot Referral Hospital, Northwest Ethiopia: A Retrospective Follow-Up Study
Introduction. Anemia is the most common hematological abnormality in Human Immunodeficiency Virus (HIV) clients, and it is a widespread public health problem. In Ethiopia, there is limited information about time to development of anemia and predictors for anemic HIV patients. Hence, this study is aimed at determining time to development of anemia and predictors among HIV/AIDS clients taking antiretroviral therapy (ART) at Felege Hiwot Referral Hospital in Bahir Dar, northwest Ethiopia. Methods. A...
BioMed Research International
Tue Mar 10, 2020 08:35
Perspectives of the Application of Liquid Biopsy in Colorectal Cancer
Colorectal cancer (CRC) is one of the most common gastrointestinal tumors and the second leading cause of cancer death worldwide. Since traditional biopsies are invasive and do not reflect tumor heterogeneity or monitor the dynamic progression of tumors, there is an urgent need for new noninvasive methods that can supplement and improve the current management strategies of CRC. Blood-based liquid biopsies are a promising noninvasive biomarker that can detect disease early, assist in staging, monitor...
BioMed Research International
Tue Mar 10, 2020 08:35
Structural Model for Estimating the Influence of Healthy Lifestyle on Episodic Memory in Adults with Subjective Memory Complaints
The aim of this study is to examine the relationships between a healthy lifestyle and episodic memory among adults with subjective memory complaints (SMCs). We proposed a structure equation model to study the association between a healthy lifestyle and episodic memory with an investigation covering 309 participants over 50 years old with SMCs. The model showed a good fit after being adjusted (,,,, and ): a healthy lifestyle has a direct positive effect on episodic memory among adults with SMCs ()....
BioMed Research International
Tue Mar 10, 2020 08:20
ARRONAX Cyclotron: Setting up of In-House Hospital Radiopharmacy
Whilst radiopharmaceuticals have an important role to play in both imaging and treatment of patients, most notably cancer patients, nuclear medicine and radiopharmacy are currently facing challenges to create innovative new drugs. Traditional radiopharmaceutical manufacture can be considered as either a routine hospital production or a large-scale industrial production. The gap between these two practices has meant that there is an inability to supply innovative radiopharmaceuticals for use at the...
BioMed Research International
Tue Mar 10, 2020 07:35
Patient-Specific or Conventional Instrumentations: A Meta-analysis of Randomized Controlled Trials
Objective. To conduct a meta-analysis of randomized controlled trials (RCTs) to compare knee arthroplasty with patient-specific instrumentation (PSI) with the conventional instrumentation (CI). Methods. RCTs were selected in PubMed and Embase from 2012 to 2018. Key data extracted included malalignment of mechanical axis, blood loss, surgical time, Oxford Knee Score (OKS), Knee Society Score (KSS), length of stay, and complications. Subgroup analysis was also performed regarding different PSI systems...
BioMed Research International
Tue Mar 10, 2020 07:35
Efficacy of Combination Therapies on Neck Pain and Muscle Tenderness in Male Patients with Upper Trapezius Active Myofascial Trigger Points
Myofascial pain syndrome, thought to be the main cause of neck pain and shoulder muscle tenderness in the working population, is characterized by myofascial trigger points (MTrPs). This study aimed to examine the immediate and short-term effect of the combination of two therapeutic techniques for improving neck pain and muscle tenderness in male patients with upper trapezius active MTrPs. This study was a pretest-posttest single-blinded randomized controlled trial. Sixty male subjects with mechanical...
BioMed Research International
Tue Mar 10, 2020 05:50
The Assessment of the Reduction Algorithm in the Treatment for “Logsplitter” Injury
As a rare and exceptional injury with significant syndesmotic disruption, the outcome of Logsplitter injury remains poor and unfavorable. In this study, we retrospectively investigated the relationship between the intraoperative reduction quality and the prognosis such as the posttraumatic osteoarthritis to help surgeons achieve better functional outcomes for this high-energy transsyndesmotic ankle fracture dislocation. From January 2015 to February 2019, 31 patients (average years with 19 male...
BioMed Research International
Tue Mar 10, 2020 05:20
International consensus on the most useful assessments used by physical therapists to evaluate patients with temporomandibular disorders: A Delphi study
Abstract Objective To identify assessment tools used to evaluate patients with temporomandibular disorders (TMD) considered to be clinically most useful by a panel of international experts in TMD physical therapy (PT). Methods A Delphi survey method administered to a panel of international experts in TMD PT was conducted over three rounds from October 2017 to June 2018. The initial contact was made by email. Participation was voluntary. An e‐survey, according to the Checklist for...
Journal of Oral Rehabilitation
Tue Mar 10, 2020 10:59
Temporal and dynamic changes in gingival blood flow during progression of ligature‐induced periodontitis
Abstract Objectives To evaluate temporal changes in gingival blood flow (GBF) during progression of periodontitis in rats using laser Doppler flowmeter (LDF) approach, and to characterize morphological and biochemical features in periodontium associated with GBF. Materials and Methods Forty‐two Wistar rats were divided into ligature‐induced periodontitis group and control group. To induce periodontitis, ligatures were tied around maxillary first molars bilaterally. GBF was measured...
Oral Diseases
Tue Mar 10, 2020 10:41
Critical appraisal of the Classification of Periodontal and Peri‐implant Diseases and Conditions (2017)
Abstract We went through the current classification of the periodontal disease and conditions and the review on dental plaque induced gingival conditions according to 2017 classification by Dr.Murakami S (Murakami et al., 2018)
Oral Diseases
Tue Mar 10, 2020 10:41
General health status of a sample of patients with Burning Mouth Syndrome: a case‐control study
Abstract Background The relationship of Burning Mouth Syndrome (BMS) with possible alterations in patients’ general health has been subject of study and controversy during the last years. Objective To analyse the general health status of patients with BMS, comparing it with a control group. Methods A case‐control study was conducted to compare the diseases, medications, blood test alterations, disturbances in general health, oral quality of life, xerostomia, sleep quality...
Oral Diseases
Tue Mar 10, 2020 10:41
CircMTO1 Attenuated Acute Kidney Injury Through Regulating miR-337
Abstract Acute kidney injury (AKI) is an independent risk factor for the increased risk of death in patients with sepsis. In the current study, we first investigated the expression of circMTO1 in sepsis-induced AKI, and the underlying mechanism was further elucidated. The results showed that circMTO1 expression level was significantly decreased in serums and kidney tissues of US rats and RMCs treated with LPS. Besides, circMTO1 overexpression...
Latest Results for Inflammation
Tue Mar 10, 2020 02:00
Molecular insights into post‐mating immune response in a fish with internal fertilization
Abstract The tight connection between immunity and reproduction has been studied for decades. However, basic knowledge at the molecular level of the effect of mating on immune function is still lacking in many taxa. Determining whether and how the immune system is engaged after mating is a crucial step in understanding post‐mating mechanisms of reproduction and sexual selection. Here we study the transcriptional changes in immunity‐related genes caused by the ejaculate in the female reproductive...
Journal of Evolutionary Biology
Tue Mar 10, 2020 10:12
Consortium of Otolaryngology Journal Editors: Collegiality and Contributions
Abstract There is a new tradition in the otolaryngology publishing community that is unique to our specialty, so far as we know. Editors‐in‐Chief of otolaryngology journals in the United States, and intermittently some of our international colleagues such as the Editor of the Journal of Laryngology and Otology (England), sit down together twice a year to discuss topics of mutual interest, maintain lines of communication and friendships, and share perspectives on the evolution of otolaryngology –...
Wiley: Clinical Otolaryngology: Table of Contents
Tue Mar 10, 2020 10:11
Analgesia for adenotonsillectomy in children: a comparison between peritonsillar infiltration of tramadol, ketamine, and placebo
Abstract Introduction Post-tonsillectomy pain is mediated by nociceptive C-fibers located at peritonsillar space. Peritonsillar infiltration of medication could relieve post-operative pain blocking the afferent via. Purpose To evaluate the effect of peritonsillar infiltration of tramadol, ketamine, and placebo on post-operative pain in cases of adenotonsillectomy....
European Archives of Oto-Rhino-Laryngology
Tue Mar 10, 2020 02:00
The (in)adequacy of translational research in dentistry
Translational research, as the name suggests, “translates” research findings into clinical practice to improve the health of human beings. The translational process builds on information from experiments conducted at a basic level (i.e., in vitro and/or animal studies) and progresses over experimental human studies for efficacy, efficiency, and safety to implementation. Therefore, all steps in the process should be based on studies conducted with the highest methodological quality possible in order...
European Journal of Oral Sciences
Tue Mar 10, 2020 09:34
Pest categorisation of Liriomyza bryoniae
Abstract The EFSA Panel on Plant Health performed a pest categorisation of Liriomyza bryoniae (Diptera: Agromyzidae) for the EU. L. bryoniae (the tomato leaf miner; EPPO code: LIRIBO) is a polyphagous Palaearctic species which probably originates from southern Europe, where it occurs commonly outdoors and has now spread to many parts of central and northern Europe, where it is only found in greenhouses. The species is also reported in North Africa and in several countries in Asia. L. bryoniae can...
Wiley: EFSA Journal: Table of Contents
Tue Mar 10, 2020 09:17
Scientific Opinion of the Scientific Panel on Plant Protection Products and their Residues (PPR Panel) on the genotoxic potential of triazine amine (metabolite common to several sulfonylurea active substances)
Abstract The Panel received a mandate from the European Commission to assess the genotoxic potential of triazine amine based on available information submitted by the applicants. Available information includes experimental genotoxicity data on triazine amine, Quantitative Structure–Activity Relationship (QSAR) analysis and read across with structurally similar compounds. Based on the overall weight of evidence, the Panel, in agreement with the cross‐cutting Working Group Genotoxicity, concluded...
Wiley: EFSA Journal: Table of Contents
Tue Mar 10, 2020 09:17
Pest categorisation of Liriomyza sativae
Abstract The EFSA Panel on Plant Health performed a pest categorisation of Liriomyza sativae (Diptera: Agromyzidae) for the EU. L. sativae (the cabbage or vegetable leaf miner; EPPO code: LIRISA) is a polyphagous pest native to the Americas which has spread to Africa, Asia and Oceania. L. sativae can have multiple overlapping generations per year. Eggs are inserted in the leaves of host plants. Three larval instars, which feed internally on field vegetables (leaves and stems), follow. Then, the...
Wiley: EFSA Journal: Table of Contents
Tue Mar 10, 2020 09:17
Risk assessment of chlorinated paraffins in feed and food
Abstract The European Commission asked EFSA for a scientific opinion on the risks for animal and human health related to the presence of chlorinated paraffins in feed and food. The data for experimental animals were reviewed and the CONTAM Panel identified the liver, kidney and thyroid as the target organs for the SCCP and MCCP mixtures tested in repeated dose toxicity studies. Decreased pup survival and subcutaneous haematoma/haemorrhage were also identified as critical effects for an MCCP mixture....
Wiley: EFSA Journal: Table of Contents
Tue Mar 10, 2020 09:17
Risk assessment of aflatoxins in food
Abstract EFSA was asked to deliver a scientific opinion on the risks to public health related to the presence of aflatoxins in food. The risk assessment was confined to aflatoxin B1 (AFB1), AFB2, AFG1, AFG2 and AFM1. More than 200,000 analytical results on the occurrence of aflatoxins were used in the evaluation. Grains and grain‐based products made the largest contribution to the mean chronic dietary exposure to AFB1 in all age classes, while ‘liquid milk’ and ‘fermented milk products’ were the...
Wiley: EFSA Journal: Table of Contents
Tue Mar 10, 2020 09:17

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