Surface texture can be perceived not only from tactile, but also from auditory and visual sensory cues. In our previous psychophysical study, we demonstrated that humans can recognize surface stickiness using only one kind of sensory modality without any difficulty. However, the brain regions that would be activated by non-corresponding sensory cues, for example, auditory and visual cues, remain unknown. In this human functional MRI study, we explored brain regions associated with surface stickiness...
Tue Mar 10, 2020 15:27
Sevoflurane has been reported to promote learning and memory disabilities by promoting neuroinflammation and neuroapoptosis. However, the precise mechanism by which sevoflurane mediating neurotoxicity remains to be determined. Cell viability, reactive oxygen species (ROS) generation, inflammation and apoptosis were measured by cell counting kit-8 assay, ROS kit, ELISA, flow cytometry and western blot assay. The abundance of small nucleolar RNA host gene 1 (SNHG1) and microRNA-181b (miR-181b) was...
Tue Mar 10, 2020 15:27
Studies show that transcranial direct current stimulation (tDCS) can modulate somatosensory processing, but optimum parameters for tDCS effects on hand sensibility remain in question. We aimed to test the effects of anodal tDCS (atDCS) and cathodal tDCS (ctDCS) compared with sham tDCS (stDCS) of primary motor (M1) and sensory (S1) cortices on healthy subjects’ hand sensibility. In this single-blind clinical trial, 30 randomized healthy volunteers received six tDCS sessions over 6 weeks: one session...
Tue Mar 10, 2020 15:27
Journal of Cutaneous Medicine and Surgery, Ahead of Print. Human papillomavirus (HPV) remains the most common sexually transmitted infection with a lifetime incidence of over 75%. Based on US data from the Centers for Disease Control and Prevention (CDC), 64% of invasive HPV-associated cancers are attributable to HPV 16 or 18 (65% for females; 63% males) and may be prevented by vaccination with either the quadrivalent or nonavalent HPV vaccine. Public HPV vaccination programs are now the norm for...
Tue Mar 10, 2020 03:17
Abstract Purpose Analyze the clinical presentation, microbiology, outcomes, and medical and surgical treatment strategies of intracranial extension of sinogenic infection in pediatric patients. Methods A retrospective, single-center study of patients < 18 years of age, presenting with intracranial extension of bacterial sinogenic infections...
Tue Mar 10, 2020 15:06
Abstract Traumatic brain injuries (TBI) are a major cause of morbidity and mortality in children. Malignant cerebral edema is described to occur more often in children than in adults. Its infratentorial analogous, a malignant cerebellar edema, has not been reported yet. A 10-year-old boy fell from a height of 3 m where he sustained a TBI. Approximately 36 h after trauma, a significant drop in Glasgow Coma Scale (GCS) occurred accompanied by bilateral fixed and dilated pupils....
Tue Mar 10, 2020 15:06
Abstract Purpose Epilepsy is a common neurological disorder that may complicate reproductive health. Our aim in this study was to provide prospective ascertainment of obstetric and neonatal outcomes in women with epilepsy and investigate whether the risk of pregnancy, delivery, and neonatal complications differed between women with epilepsy and women without epilepsy. ...
Tue Mar 10, 2020 15:06
Tue Mar 10, 2020 15:06
Tue Mar 10, 2020 15:06
Abstract Purpose We aimed to identify factors that affect the time to diagnosis in pediatric brain tumors and investigate the effect of time to diagnosis on clinical outcome. Methods A retrospective study of children with brain tumors aged less than 18 years diagnosed at the University of Tsukuba Hospital over a period of 7 years was conducted. ...
Tue Mar 10, 2020 02:00
Abstract Background and importance Angiosarcoma is a rare malignant tumor with an aggressive course and poor prognosis. It is typically seen in adults but very rarely seen in children. Angiosarcoma of the skull with brain metastasis is exceptionally rare. Due to the rare nature of these tumors, much is left unknown about clinical progression and treatment guidelines are not well established. ...
Tue Mar 10, 2020 02:00
AbstractThe chorda tympani nerve (CT) is exceptionally responsive to NaCl. Amiloride, an epithelial Na+ channel (ENaC) blocker, consistently and significantly decreases the NaCl responsiveness of the CT but not the glossopharyngeal (GL) nerve in the rat. Here, we examined whether amiloride would suppress the NaCl responsiveness of the CT when it cross-reinnervated the posterior tongue (PT). Whole-nerve electrophysiological recording was performed to investigate the response properties of the intact...
Tue Mar 10, 2020 02:00
Abstract Tuberculosis is one of the major causes of ill health and death worldwide. Primary tuberculosis of the oral cavity and oropharynx is usually uncommon. Among tuberculosis of oral cavity and oropharynx, primary tuberculosis of tonsil in the absence of active pulmonary tuberculosis is a very rare clinical entity which presents difficulties in diagnosis because of similarity of presentation of carcinoma tonsil. Diagnosis mainly relies on the treating surgeon having a high...
Tue Mar 10, 2020 02:00
Tue Mar 10, 2020 14:57
Abstract Background Cytology specimens are the main samples used for the diagnosis of advanced lung cancer. The objective of our study was to assess anaplastic lymphoma kinase (ALK) and c‐ros oncogene 1 receptor tyrosine kinase (ROS1) genes by an amplification refractory mutation system (ARMS)‐polymerase chain reaction (PCR) using cytology specimens and to then evaluate the mutation frequency of ALK and ROS1 in non‐small‐cell lung cancer (NSCLC) patients. Methods A large cohort that...
Tue Mar 10, 2020 10:50
Abstract Background We designed this retrospective study to explore the best treatment modality for patients with initially metastatic nasopharyngeal carcinoma (NPC). Methods From 2008 to 2017, 821 patients were enrolled. Treatment modalities and prognostic factors were analyzed. Results Compared with chemotherapy alone and radiotherapy‐based treatment, systemic chemotherapy‐sequential locoregional radiotherapy to the nasopharyngeal primary tumor site were associated with...
Tue Mar 10, 2020 14:44
Abstract Human papillomavirus (HPV) in oropharyngeal squamous cell carcinoma (SCC) is a well‐known cause and prognostic indicator, and the utility of p16 as a surrogate marker for HPV status has been established. P16 and its relationship with HPV have not been defined in sinonasal malignancy nor has a link with outcomes been established. Patients with sinonasal SCC from 2011 to 2017 were identified from our pathology database. P16 immunohistochemistry and HPV RNA in situ hybridization were performed...
Tue Mar 10, 2020 10:46
Tue Mar 10, 2020 02:00
65 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: upper respiratory tract infection These pubmed results were generated on 2020/03/10PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Tue Mar 10, 2020 14:41
65 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: upper respiratory tract infection These pubmed results were generated on 2020/03/10PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Tue Mar 10, 2020 12:41
16 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "Ann Plast Surg"[jour] These pubmed results were generated on 2020/03/10PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Tue Mar 10, 2020 14:41
16 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "Ann Plast Surg"[jour] These pubmed results were generated on 2020/03/10PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Tue Mar 10, 2020 12:37
Thyroid disease in pregnant women needs attention from a clinical and scientific standpoint due to the potential severe adverse consequences. It is well-established that overt thyroid disease in pregnant women should be treated to prevent maternal and fetal complications, but routine testing for overt thyroid function test abnormalities has not been implemented. In contrast, the scientific focus has shifted towards smaller aberrations in maternal thyroid function including subclinical thyroid disease...
Tue Mar 10, 2020 12:40
Aortic dissection (AD) is a heterogeneous genetic disease with high morbidity and mortality. Although many genes predispose patients to AD, the pathogenic spectrum remains incomplete. This study aimed to 1) investigate whether genotype differences exist between Stanford A and B AD individuals, and 2) broaden the pathogenic genetic spectrum of AD and reported novel variants of AD‐associated genes. The DNA of 72 unrelated Han Chinese individuals with AD was tested by whole‐exome sequencing....
Tue Mar 10, 2020 14:38
Publication date: Available online 10 March 2020Source: Autoimmunity ReviewsAuthor(s): Yu Pei Chock, Thomas Moulinet, Virginie Dufrost, Doruk Erkan, Denis Wahl, Stéphane Zuily
Tue Mar 10, 2020 14:33
Tuberous sclerosis complex is a multisystemic genetic disorder with high phenotypical variability. Its progress frequently brings along autism (61%), epilepsy, intellectual disability (45%), and neurocognitive impairment (Gipson and Johnston, 2017). We are considering the case of an infant suspected with tuberous sclerosis complex by imagistic investigation in the prenatal period. The pre- and postnatal ultrasound, fetal MRI, ophthalmoscopy, and dermatological and neurological examinations were used...
Tue Mar 10, 2020 14:05
97 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: ALCOHOL These pubmed results were generated on 2020/03/10PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Tue Mar 10, 2020 14:24
97 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: ALCOHOL These pubmed results were generated on 2020/03/10PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Tue Mar 10, 2020 12:28
Related ArticlesThe global transcriptomic signature in sinonasal tissues reveals roles for tissue type and chronic rhinosinusitis disease phenotype. Rhinology. 2020 Mar 09;: Authors: Bassiouni A, Ou J, Schreiber A, Geoghegan J, Tsykin A, Psaltis AJ, Wormald PJ, Vreugde S Abstract BACKGROUND: RNA sequencing (RNA-Seq) allows the characterization of a global transcriptomic signature in a least-biased fashion, but few studies have applied this method to...
Tue Mar 10, 2020 14:15
The present study aimed to evaluate the effect of MOP over a 3-month period and to determine the influence of the number of perforations on the rate of canine retraction. In addition, the amount of pain and di...
Mon Mar 09, 2020 02:00
Abstract 3q29 duplication syndrome (3q29dup) is a rare genomic disorder caused by a 1.6 Mb duplication (GRCh38 chr3:195,998,000‐197,623,000). Case reports indicate the 3q29dup is likely to be pathogenic, but the full range of manifestations is not well understood. We used the 3q29 registry (https://3q29deletion.patientcrossroads.org/https://3q29.com) to ascertain 31 individuals with 3q29dup, the largest cohort ever surveyed in a systematic way. For comparison, we ascertained 117 individuals with...
Tue Mar 10, 2020 14:02
Related ArticlesProspective cohort study on the predictors of fall risk in 119 patients with bilateral vestibulopathy. PLoS One. 2020;15(3):e0228768 Authors: Dobbels B, Lucieer F, Mertens G, Gilles A, Moyaert J, van de Heyning P, Guinand N, Pérez Fornos A, Herssens N, Hallemans A, Vereeck L, Vanderveken O, Van Rompaey V, van de Berg R Abstract OBJECTIVES: To identify predictive factors for falls in patients with bilateral vestibulopathy (BV). Specific...
Tue Mar 10, 2020 14:01
Related ArticlesVestibular evoked myogenic potentials: what are they for? An opinion; a hypothesis. Acta Otolaryngol. 2020 Mar 09;:1-3 Authors: Longridge NS PMID: 32149556 [PubMed - as supplied by publisher]
Tue Mar 10, 2020 14:01
3565 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2020/03/10PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Tue Mar 10, 2020 13:58
23 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2020/03/10PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Tue Mar 10, 2020 13:58
23 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2020/03/10PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Tue Mar 10, 2020 12:57
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