Objective. To systematically evaluate the effects of red yeast rice (RYR) and its extract on bone formation in experimental animals and to provide reference data for clinical research on the treatment of osteoporosis. Methods. Chinese and English language databases, including Web of Science, PubMed, the Cochrane Library, Elsevier, Google Scholar, SpringerLink, Embase, China National Knowledge Infrastructure (CNKI), Weipu Chinese Sci-tech periodical full-text database (VIP), and Wanfang Data Knowledge...
Sat Aug 08, 2020 16:50
Background. Neonatal sepsis (NS) is a very critical medical situation associated with high morbidities and mortalities. There is an utmost need for a new tool helping in early diagnosis and proper management of sepsis neonates. Neutrophil CD64 (nCD64) shows a very promising value in this concerning issue. Aim. Evaluate the diagnostic, monitoring, and prognostic performances of nCD64 and highly sensitive CRP (hs-CRP) in NS as well as the possible best panel of biomarkers that can achieve the most...
Sat Aug 08, 2020 09:05
Esophageal cancer (EC) is a type of extremely aggressive gastrointestinal cancer with high incidences in China and other Asian countries. EC does not have specific symptoms and is relatively easy to metastasize, which makes it difficult in early diagnosis. Thus, novel noninvasive diagnostic method is urgently needed in clinical practice. In this study, mass spectrometry with tandem mass tags and differential protein analysis were applied for identifying esophageal cancer-related proteins. The identified...
Sat Aug 08, 2020 09:05
A systemic design was carried out to investigate the optimal combination of BET, Met-Cr, CLA, and CS for improving the meat tenderness in rats. A total of 104 six-week old male Sprague-Dawley rats were randomly assigned to 13 treatments with 4 replicates of 2 rats each. The experiments lasted for 5 weeks. The results showed that inclusion of Met-Cr decreased the contents of intramuscular fat (IMF), fat among muscle cells, and lipid droplets inside muscle cells (), and inclusion of CLA or Met-Cr increased...
Sat Aug 08, 2020 09:05
Introduction. Hypoxia-induced ανβ3 integrin and aminopeptidase N (APN/CD13) receptor expression play an important role in tumor neoangiogenesis. APN/CD13-specific 68Ga-NOTA-c(NGR), ανβ3 integrin-specific 68Ga-NODAGA-[c(RGD)]2, and hypoxia-specific 68Ga-DOTA-nitroimidazole enable the in vivo detection of the neoangiogenic process and the hypoxic regions in the tumor mass using positron emission tomography (PET) imaging. The aim of this study was to evaluate whether 68Ga-NOTA-c(NGR) and 68Ga-DOTA-nitroimidazole...
Fri Aug 07, 2020 16:35
Background. Meningioma is a prevalent type of brain tumor. However, the initiation and progression mechanisms involved in the meningioma are mostly unknown. This study aimed at exploring the potential transcription factors/micro(mi)RNAs/genes and biological pathways associated with meningioma. Methods. mRNA expressions from GSE88720, GSE43290, and GSE54934 datasets, containing data from 83 meningioma samples and eight control samples, along with miRNA expression dataset GSE88721, which had 14 meningioma...
Fri Aug 07, 2020 16:20
Emodin is an active monomer extracted from rhubarb root, which has many biological functions, including anti-inflammation, antioxidation, anticancer, and neuroprotection. However, the protective effect of emodin on nerve injury needs to be further elucidated. The purpose of this study is to investigate the effect of emodin on the neuroprotection and the special molecular mechanism. Here, the protective activity of emodin inhibiting H2O2-induced apoptosis and neuroinflammation as well as its molecular...
Fri Aug 07, 2020 09:35
The purpose of this study was to explore the relationship between stromal cell-derived factor 2-like 1 (SDF2L1) and nasopharyngeal carcinoma (NPC). 12 NPC tissues and 12 chronic nasopharyngitis tissues were involved in our study. Quantitative real-time PCR (qRT-PCR) and Western Blot were utilized to detect the expression of SDF2L1. Besides, immunofluorescence analysis was utilized to determine the protein expression of 97 paraffin-embedded NPC tissues and 58 nasopharyngitis tissues. Biological functional...
Fri Aug 07, 2020 09:35
Background. Podoconiosis is one of the neglected tropical diseases, and it is a nonfilarial elephantiasis caused by prolonged barefoot exposure to irritant soil. This is manifested by slowly progressive swelling of the foot and lower leg which may lead to an irreversible disability among affected people. Podoconiosis is an entirely noncommunicable preventable disease with a low-cost preventive mechanism. This study is aimed at assessing the magnitude and factor affecting Podoconiosis in Waghmra zone,...
Fri Aug 07, 2020 09:05
Electronics giant Samsung recently held their virtual “Galaxy Unpacked” event where they announced the latest upgrades to their popular mobile devices. Along with phones, tablets, and earbuds, Samsung unveiled the newest version of their smartwatch, the Galaxy Watch3. The Watch3 has several new features and upgrades that make it a worthy competitor to the Apple Watch, but perhaps where it stands out this year is its emphasis on health management. Like other smartwatches,...
Fri Aug 07, 2020 17:31
For several years, the multidrug resistance (MDR) of gastric cancer cells has been a thorny issue worldwide regarding the chemotherapy process and needs to be solved. Here, we report that the ARK5 gene could promote the multidrug resistance of gastric cancer cells in vitro and in vivo. In this study, LV-ARK5-RNAi lentivirus was used to transfect the parental cell line SGC7901 and MDR cell line SGC7901/DDP to construct a stable model of ARK5 interference. Subsequently, the cells were treated with...
Fri Aug 07, 2020 03:00
Many conservation instruments rely on detecting and estimating a population decline in a target species to take action. Trend estimation is difficult because of small sample size and relatively large uncertainty in abundance/density estimates of many wild populations of animals. Focusing on cetaceans, we performed a prospective analysis to estimate power, type-I, sign (type-S) and magnitude (type-M) error rates of detecting a decline in short time-series of abundance estimates with different signal-to-noise...
Fri Aug 07, 2020 03:00
Background The distribution and use of camphor (Cinnamomum camphora L.) trees are constrained by increasing soil salinity in south-eastern China along the Yangtze River. However, the response mechanism of this species to salinity, especially in team of photosynthesis, are unknown. Methods Here, we analysed themorphological, physiological, ultrastructural, and proteomic traits of camphor seedlings under NaCl (103.45 mM)...
Fri Aug 07, 2020 03:00
In Central and North America, Australia and New Zealand, potato (Solanum tuberosum) crops are attacked by Bactericera cockerelli, the tomato potato psyllid (TPP). ‘Mesh crop covers’ which are used in Europe and Israel to protect crops from insect pests, have been used experimentally in New Zealand for TPP control. While the covers have been effective for TPP management, the green peach aphid (GPA, Myzus persicae) has been found in large numbers under the mesh crop covers. This study investigated...
Fri Aug 07, 2020 03:00
The purpose of a forecast, in making an estimate about the future, is to give people information to act on. In the case of a coupled human system, a change in human behavior caused by the forecast can alter the course of events that were the subject of the forecast. In this context, the forecast is an integral part of the coupled human system, with two-way feedback between forecast output and human behavior. However, forecasting programs generally do not examine how the forecast might affect the...
Fri Aug 07, 2020 03:00
Background Mycobacterium ulcerans is the causative agent of a debilitating skin and soft tissue infection known as Buruli ulcer (BU). There is no vaccine against BU. The purpose of this study was to investigate the vaccine potential of two previously described immunogenic M. ulcerans proteins, MUL_3720 and Hsp18, using a mouse tail infection model of BU. Methods Recombinant versions of the two proteins were each electrostatically...
Fri Aug 07, 2020 03:00
Publication date: Available online 8 August 2020Source: International Journal of Radiation Oncology*Biology*PhysicsAuthor(s): Umair Mahmood, Andrew Bang, Yu-Hui Chen, Raymond H. Mak, Jochen H. Lorch, Glenn J. Hanna, Mizuki Nishino, Claire Manuszak, Emily M. Thrash, Mariano Severgnini, Matthew Sanborn, Vishwajith Sridharan, Danielle N. Margalit, Roy B. Tishler, Paul M. Busse, Henning Willers, Harvey J. Mamon, Hyung-Jin Yoo, Sara I. Pai, Lori J. Wirth
Sun Aug 09, 2020 22:39
Publication date: Available online 8 August 2020Source: International Journal of Radiation Oncology*Biology*PhysicsAuthor(s): Grace Lee, Nayan Lamba, Andrzej Niemierko, Daniel W. Kim, Paul H. Chapman, Jay S. Loeffler, William T. Curry, Robert L. Martuza, Kevin S. Oh, Fred G. Barker, Helen A. Shih
Sat Aug 08, 2020 19:47
Publication date: Available online 8 August 2020Source: International Journal of Radiation Oncology*Biology*PhysicsAuthor(s): Evangelia (Eva) Katsoulakis
Sat Aug 08, 2020 19:47
Publication date: Available online 7 August 2020Source: International Journal of Radiation Oncology*Biology*PhysicsAuthor(s): Carlo Greco, Richard Kolesnick, Zvi Fuks
Sat Aug 08, 2020 19:47No more articles here.
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