Abstract The implementation of the Grain for Green Program (GGP) has changed the development track of the agricultural eco-economic system in China. In response to the results of a lag study that investigated the coupling between the GGP and the agricultural eco-economic system in a loess hilly region, we used a structural equation model to analyze the survey data from 494 households in Ansai, a district of Yan’an City in Shaanxi Province of China in 2015. The model clarified the...
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Abstract Regulation of leaf gas exchange plays an important role in the survival of trees and shrubs under future climate change. However, the responses of leaf water potential and gas exchange of shrubs in semi-arid areas to the precipitation alteration are not clear. Here, we conducted a manipulated experiment with three levels of precipitation, i.e., a control with ambient precipitation, 50% above ambient precipitation (irrigation treatment), and 50% below ambient precipitation...
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Abstract Ecosystems in high-altitude regions are more sensitive and respond more rapidly than other ecosystems to global climate warming. The Qinghai-Tibet Plateau (QTP) of China is an ecologically fragile zone that is sensitive to global climate warming. It is of great importance to study the changes in aboveground biomass and species diversity of alpine meadows on the QTP under predicted future climate warming. In this study, we selected an alpine meadow on the QTP as the study...
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Abstract Shrubby seablite or lani (Suaeda fruticosa Forssk) is a perennial euhalophyte with succulent leaves, which could be planted on arid-saline lands for restoration and cultivated as a non-conventional edible or cash crop. Knowledge about the impacts of maternal saline environment on seed attributes of this important euhalophyte is lacking. This study investigated the effects of maternal salinity on yield, size and stress tolerance of S. fruticosa seeds. Seedlings of S. fruticosa...
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Abstract Aim Osteopontin (OPN) has been investigated as a biomarker for cancer and nonmalignant diseases during the last decades. Data about OPN as a potential biomarker in childhood diseases are still sparse, and reference values are not available in children. We aimed to establish reference values for children from birth to young adulthood and evaluate whether there are age‐, gender‐, and weight‐specific differences. Method Umbilical cord blood and blood plasma samples of 117 children...
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Cancers, Vol. 12, Pages 832: Landscape and Future Perspectives of Immunotherapy in Neuroendocrine Neoplasia Cancers doi: 10.3390/cancers12040832 Authors: Maggio Manuzzi Lamberti Ricci Tober Campana Background: Neuroendocrine neoplasms are rare entities consisting of a heterogeneous group of tumors that can originate from neuroendocrine cells present in the whole body. Their different behavior, metastatic potential, and prognosis are highly variable, depending...
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Cancers, Vol. 12, Pages 833: An Easy-To-Use Survival Score Compared to Existing Tools for Older Patients with Cerebral Metastases from Colorectal Cancer Cancers doi: 10.3390/cancers12040833 Authors: Dirk Rades Trang Nguyen Stefan Janssen Steven E. Schild An easy-to-use survival score was developed specifically for older patients with cerebral metastases from colorectal cancer, and was compared to existing tools regarding the accuracy of identifying patients who die in...
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Cancers, Vol. 12, Pages 831: Preclinical Study Using ABT263 to Increase Enzalutamide Sensitivity to Suppress Prostate Cancer Progression Via Targeting BCL2/ROS/USP26 Axis Through Altering ARv7 Protein Degradation Cancers doi: 10.3390/cancers12040831 Authors: Xu Sun Huang You Ye Chang : Background: The recently developed antiandrogen, Enzalutamide (Enz), has reformed the standard of care for castration resistant prostate cancer (CRPC) patients. However,...
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Cancers, Vol. 12, Pages 828: BRCA1 Promoter Hypermethylation is Associated with Good Prognosis and Chemosensitivity in Triple-Negative Breast Cancer Cancers doi: 10.3390/cancers12040828 Authors: Jacot Lopez-Crapez Mollevi Boissière-Michot Simony-Lafontaine Ho-Pun-Cheung Chartron Theillet Lemoine Saffroy Lamy Guiu The aberrant hypermethylation of BRCA1 promoter CpG islands induces the decreased expression of BRCA1 (Breast Cancer...
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Cancers, Vol. 12, Pages 827: xCT Inhibition Increases Sensitivity to Vorinostat in a ROS-Dependent Manner Cancers doi: 10.3390/cancers12040827 Authors: Miyamoto Watanabe Boku Sukeno Morita Kondo Sakaguchi Taguchi Sakai As histone deacetylase inhibitors (HDACIs) have limited efficacy against solid tumors, we investigated whether and how oxidative stress is involved in sensitivity to HDACIs to develop a novel therapeutic option of HDACIs treatment....
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Cancers, Vol. 12, Pages 830: Optimal Body Mass Index Cut-off Point for Predicting Colorectal Cancer Survival in an Asian Population: A National Health Information Database Analysis Cancers doi: 10.3390/cancers12040830 Authors: Nan Song Dan Huang Doeun Jang Min Jung Kim Seung-Yong Jeong Aesun Shin Ji Won Park The optimal body mass index (BMI) range for predicting survival in Asian colorectal cancer patients is unknown. We established the most appropriate cut-off...
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Cancers, Vol. 12, Pages 829: Exploring the Role of Mutations in Fanconi Anemia Genes in Hereditary Cancer Patients Cancers doi: 10.3390/cancers12040829 Authors: Jesús del Valle Paula Rofes José Marcos Moreno-Cabrera Adriana López-Dóriga Sami Belhadj Gardenia Vargas-Parra Àlex Teulé Raquel Cuesta Xavier Muñoz Olga Campos Mónica Salinas Rafael de Cid Joan Brunet Sara González Gabriel Capellá Marta Pineda Lídia Feliubadaló Conxi...
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Cancers, Vol. 12, Pages 825: Pan-Cancer Analysis of Mitochondria Chaperone-Client Co-Expression Reveals Chaperone Functional Partitioning Cancers doi: 10.3390/cancers12040825 Authors: Geut Galai Hila Ben-David Liron Levin Martin F. Orth Thomas G. P. Grünewald Shai Pilosof Shimon Berstein Barak Rotblat Metabolic reprogramming is a hallmark of cancer. Such reprogramming entails the up-regulation of the expression of specific mitochondrial proteins, thus...
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Cancers, Vol. 12, Pages 826: Cardiovascular Toxicity of Tyrosine Kinase Inhibitors Used in Chronic Myeloid Leukemia: An Analysis of the FDA Adverse Event Reporting System Database (FAERS) Cancers doi: 10.3390/cancers12040826 Authors: Santa Cirmi Asmae El Abd Louis Letinier Michele Navarra Francesco Salvo Tyrosine kinase inhibitors (TKIs), the treatment of choice for chronic myeloid leukemia (CML), can be associated to cardiovascular (CV) adverse events (AEs). A case/non-case...
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Antibiotics, Vol. 9, Pages 148: Development of Staphylococcus Enzybiotics: The Ph28 Gene of Staphylococcus epidermidis Phage PH15 Is a Two-Domain Endolysin Antibiotics doi: 10.3390/antibiotics9040148 Authors: Muharram Abulhamd Aldawsari Alqarni Labrou Given the worldwide increase in antibiotic resistant bacteria, bacteriophage derived endolysins represent a very promising new alternative class of antibacterials in the fight against infectious diseases. Endolysins...
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Antibiotics, Vol. 9, Pages 147: Essential Oils of Aromatic Plants with Antibacterial, Anti-Biofilm and Anti-Quorum Sensing Activities against Pathogenic Bacteria Antibiotics doi: 10.3390/antibiotics9040147 Authors: Marlon Cáceres William Hidalgo Elena Stashenko Rodrigo Torres Claudia Ortiz Both the ability of bacteria to form biofilms and communicate through quorum sensing allows them to develop different survival or virulence traits that lead to increased bacterial...
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Antibiotics, Vol. 9, Pages 146: Peer-Education as a Tool to Educate on Antibiotics, Resistance and Use in 16–18-Year-Olds: A Feasibility Study Antibiotics doi: 10.3390/antibiotics9040146 Authors: Cliodna A. M. McNulty Rowshonara B. Syeda Carla L. Brown C. Verity Bennett Behnaz Schofield David G. Allison Neville Q. Verlander Nick Francis Peer education (PE) interventions may help improve knowledge and appropriate use of antibiotics in young adults. In...
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Sitagliptin inhibits the proliferation and clonality of gastric cancer cells, which was accompanied by increased levels of adenosine 5′‐monophosphate‐activated protein kinase phosphorylation and Yes‐associated protein (YAP) phosphorylation expression and decreased YAP nuclear localization. In addition, sitagliptin reduces melanoma‐associated antigen‐A3 expression via the YAP pathway, which may improve the prognosis of gastric cancer. Abstract Sitagliptin is an emerging oral hypoglycemic agent that...
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Photochem. Photobiol. Sci., 2020, Accepted ManuscriptDOI: 10.1039/D0PP00065E, PerspectiveLara Martínez-Fernández, Luciana Esposito, Roberto ImprotaThe main insights on the photoactivated dynamics of Guanine quadruplexes (G4s) recently provided by Quantum Mechanical computations are concisely reviewed here. The experimental steady state absorption and circular dichroism spectra...The content of this RSS Feed (c) The Royal Society of Chemistry
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Publication date: Available online 29 March 2020Source: Journal of Controlled ReleaseAuthor(s): Yuan He, Zhuyifan Ye, Xinyang Liu, Zhengjie Wei, Fen Qiu, Hai-Feng Li, Ying Zheng, Defang Ouyang
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Abstract Introduction Patients with moderate to severe obstructive sleep apnea (OSA) have an increased risk of cardiovascular comorbidities and mortality. Although different subtypes of OSA have been described, data about oximetric parameters and their suitability to identify a different phenotype are scant. In this study, we evaluate the association between moderate to severe OSA and oximetric parameters included in the home sleep apnea...
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Background Poor adherence to sublingual immunotherapy (SLIT) has become a major cause of unsatisfactory clinical efficacy for patients with allergic rhinitis (AR). This study was designed to identify the effect of different first prescription lengths on the adherence to SLIT. Methods The clinical data of 306 patients with AR who started SLIT between January 2017 and June 2018 were retrospectively reviewed. Patients were divided into 3 groups according to the length of their first prescription...
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Publication date: Available online 29 March 2020Source: Biochimica et Biophysica Acta (BBA) - Proteins and ProteomicsAuthor(s): Shihua Li, Kai Yu, Dawei Wang, Qingfeng Zhang, Linhong Zhao, Ze-Xian Liu, Han Cheng
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Publication date: Available online 30 March 2020Source: GeneAuthor(s): Junjie Wu, Chang Lu, Si Ge, Jie Mei, Xiaohui Li, Wenjie Guo
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Essential tremor (ET) is a disabling movement disorder that is most prevalent among the elderly. While deep brain stimulation surgery targeting the ventral intermediate nucleus of the thalamus is commonly used to treat ET, the most elderly patients or those with multiple medical comorbidities may not qualify as surgical candidates. Magnetic resonance-guided focused ultrasound (MRgFUS) constitutes a less invasive modality that may be used to perform thalamotomy without the need for a burr hole craniotomy....
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Introduction: The rate of intracranial hemorrhage (ICH) after deep brain stimulation (DBS) is between 1.5 and 6.1%, with prolonged deficits occurring in 0.4–2.5% of the patients. This retrospective study investigates whether the prophylactic administration of tranexamic acid (TA) to patients with abnormal platelet function detected preoperatively by platelet function analyzer (PFA) lowered the risk for an ICH event. Methods: We performed a systematic review of the medical records of 485 consecutively...
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JSAN, Vol. 9, Pages 18: Swarm-Based Parallel Control of Adjacent Irregular Buildings Considering Soil–Structure Interaction Journal of Sensor and Actuator Networks doi: 10.3390/jsan9020018 Authors: Azimi Yeznabad Seismic behavior of tall buildings depends upon the dynamic characteristics of the structure, as well as the base soil properties. To consider these factors, the equations of motion for a multi-story 3D building are developed to include irregularity and soil–structure...
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Publication date: Available online 30 March 2020Source: Cellular SignallingAuthor(s): Shan Gao, Wei Hu, Xin Huang, Xingyue Huang, Wenwei Chen, Lidan Hao, Zubing Chen, Jian Wang, Hailiang Wei
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Publication date: Available online 30 March 2020Source: Cellular SignallingAuthor(s): Ai-Mei Gao, Chunyan Yuan, Ai-Xin Hu, Xiang-Sheng Liu
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41 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: quality of care These pubmed results were generated on 2020/03/30PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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41 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: quality of care These pubmed results were generated on 2020/03/30PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Introduction: Although growth hormone (GH) is essential for attainment of peak bone mass, bone health in prepubertal children with GH deficiency is not routinely evaluated. The objective of this study was to evaluate bone microarchitecture in GH-deficient (GHD) boys using high-resolution peripheral quantitative computed tomography (HR-pQCT). Methods: Fifteen control and fifteen GHD, GH naïve pre-pubertal boys were recruited for a case-control study at a major academic center. Subjects with panhypopituitarism,...
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AbstractAutoimmune haemolytic anaemia (AIHA) and paroxysmal nocturnal haemoglobinuria (PNH) are two distinct causes of haemolytic anaemia. They have different mechanisms that underpin their pathogenesis and, therefore, require different treatment strategies. The direct antiglobulin test (DAT) or Coombs test is positive in cases of immune-mediated haemolytic anaemia and, thus, is positive in AIHA but negative in PNH. We report a case of a woman presenting with a haemolytic anaemia who was found to...
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