IJMS, Vol. 21, Pages 2383: Chitosan Modified Zeolite Molecular Sieve Particles as a Filter for Ammonium Nitrogen Removal from Water International Journal of Molecular Sciences doi: 10.3390/ijms21072383 Authors: Yunan Gao Jiayu Zhang Drinking water containing a high amount of ammonium-nitrogen (NH4+-N) is not effectively removed by conventional treatment processes and can cause eutrophication. In this research, a composite adsorbent based on chitosan crosslink with zeolite molecular...
Mon Mar 30, 2020 03:00
IJMS, Vol. 21, Pages 2376: Nanogels of a Succinylated Glycol Chitosan-Succinyl Prednisolone Conjugate: Release Behavior, Gastrointestinal Distribution, and Systemic Absorption International Journal of Molecular Sciences doi: 10.3390/ijms21072376 Authors: Haiyan Zhou Yuri Ikeuchi-Takahashi Yoshiyuki Hattori Hiraku Onishi Recently, the potential of nanoparticles (NPs) in ulcerative colitis (UC) therapy has been increasingly demonstrated. Namely, anionic NPs have been found to...
Mon Mar 30, 2020 03:00
IJMS, Vol. 21, Pages 2378: Molecular T-Cell Repertoire Analysis as Source of Prognostic and Predictive Biomarkers for Checkpoint Blockade Immunotherapy International Journal of Molecular Sciences doi: 10.3390/ijms21072378 Authors: Ilenia Aversa Donatella Malanga Giuseppe Fiume Camillo Palmieri The T cells are key players of the response to checkpoint blockade immunotherapy (CBI) and monitoring the strength and specificity of antitumor T-cell reactivity remains a crucial but...
Mon Mar 30, 2020 03:00
IJMS, Vol. 21, Pages 2375: Health Impact of Silver Nanoparticles: A Review of the Biodistribution and Toxicity Following Various Routes of Exposure International Journal of Molecular Sciences doi: 10.3390/ijms21072375 Authors: Zannatul Ferdous Abderrahim Nemmar Engineered nanomaterials (ENMs) have gained huge importance in technological advancements over the past few years. Among the various ENMs, silver nanoparticles (AgNPs) have become one of the most explored nanotechnology-derived...
Mon Mar 30, 2020 03:00
IJMS, Vol. 21, Pages 2371: Proteomic Analysis of Renal Biomarkers of Kidney Allograft Fibrosis—A Study in Renal Transplant Patients International Journal of Molecular Sciences doi: 10.3390/ijms21072371 Authors: Line Aas Mortensen Anne Marie Svane Mark Burton Claus Bistrup Helle Charlotte Thiesson Niels Marcussen Hans Christian Beck Renal transplantation is the preferred treatment of end stage renal disease, but allograft survival is limited by the development of interstitial...
Mon Mar 30, 2020 03:00
IJMS, Vol. 21, Pages 2373: The Position and Complex Genomic Architecture of Plant T-DNA Insertions Revealed by 4SEE International Journal of Molecular Sciences doi: 10.3390/ijms21072373 Authors: Ronen Krispil Miriam Tannenbaum Avital Sarusi-Portuguez Olga Loza Olga Raskina Ofir Hakim The integration of T-DNA in plant genomes is widely used for basic research and agriculture. The high heterogeneity in the number of integration events per genome, their configuration, and...
Mon Mar 30, 2020 03:00
IJMS, Vol. 21, Pages 2374: Genetic and Clinical Heterogeneity in Thirteen New Cases with Aceruloplasminemia. Atypical Anemia as a Clue for an Early Diagnosis International Journal of Molecular Sciences doi: 10.3390/ijms21072374 Authors: Marc Vila Cuenca Giacomo Marchi Anna Barqué Clara Esteban-Jurado Alessandro Marchetto Alejandro Giorgetti Viorica Chelban Henry Houlden Nicholas W Wood Chiara Piubelli Marina Dorigatti Borges Dulcinéia Martins de Albuquerque...
Mon Mar 30, 2020 03:00
IJMS, Vol. 21, Pages 2370: Photobiomodulation Mediates Neuroprotection against Blue Light Induced Retinal Photoreceptor Degeneration International Journal of Molecular Sciences doi: 10.3390/ijms21072370 Authors: Nora Heinig Ulrike Schumann Daniela Calzia Isabella Panfoli Marius Ader Mirko H. H. Schmidt Richard H. W. Funk Cora Roehlecke Potent neuroprotective effects of photobiomodulation with 670 nm red light (RL) have been demonstrated in several models of retinal...
Mon Mar 30, 2020 03:00
IJMS, Vol. 21, Pages 2369: Modulatory Effects of Silymarin on Benzo[a]pyrene-Induced Hepatotoxicity International Journal of Molecular Sciences doi: 10.3390/ijms21072369 Authors: Seung-Cheol Jee Min Kim Jung-Suk Sung Benzo[a]pyrene (B[a]P), a polycyclic aromatic hydrocarbon, is a group 1 carcinogen that introduces mutagenic DNA adducts into the genome. In this study, we investigated the molecular mechanisms underlying the involvement of silymarin in the reduction of DNA adduct...
Mon Mar 30, 2020 03:00
IJMS, Vol. 21, Pages 2368: Analysis of Intracellular Magnesium and Mineral Depositions during Osteogenic Commitment of 3D Cultured Saos2 Cells International Journal of Molecular Sciences doi: 10.3390/ijms21072368 Authors: Giovanna Picone Concettina Cappadone Alice Pasini Joseph Lovecchio Marilisa Cortesi Giovanna Farruggia Marco Lombardo Alessandra Gianoncelli Lucia Mancini Menk Ralf H. Sandro Donato Emanuele Giordano Emil Malucelli Stefano Iotti ...
Mon Mar 30, 2020 03:00
IJMS, Vol. 21, Pages 2367: Modern Aspects of Immunotherapy with Checkpoint Inhibitors in Melanoma International Journal of Molecular Sciences doi: 10.3390/ijms21072367 Authors: Vera Petrova Ihor Arkhypov Rebekka Weber Christopher Groth Peter Altevogt Jochen Utikal Viktor Umansky Although melanoma is one of the most immunogenic tumors, it has an ability to evade anti-tumor immune responses by exploiting tolerance mechanisms, including negative immune checkpoint molecules....
Mon Mar 30, 2020 03:00
IJNS, Vol. 6, Pages 28: Pancreatitis-Associated Protein in Neonatal Screening for Cystic Fibrosis: Strengths and Weaknesses International Journal of Neonatal Screening doi: 10.3390/ijns6020028 Authors: Olaf Sommerburg Jutta Hammermann There are currently four countries and one local region in Europe that use PAP in their newborn screening programme. The first country to employ PAP at a national level was the Netherlands, which started using IRT/PAP/DNA/EGA in 2011. Germany followed...
Mon Mar 30, 2020 03:00
IJNS, Vol. 6, Pages 27: Psychological Impact of NBS for CF International Journal of Neonatal Screening doi: 10.3390/ijns6020027 Authors: Chudleigh Chinnery Newborn screening for cystic fibrosis has resulted in diagnosis often before symptoms are recognised, leading to benefits including reduced disease severity, decreased burden of care, and lower costs. The psychological impact of this often unsought diagnosis on the parents of seemingly well children is less well understood. The...
Mon Mar 30, 2020 03:00
JCM, Vol. 9, Pages 932: The Effects of SJP-001 on Alcohol Hangover Severity: A Pilot Study Journal of Clinical Medicine doi: 10.3390/jcm9040932 Authors: Joris C Verster Thomas A Dahl Andrew Scholey Jacqueline M Iversen Background. Despite a clear market need and many hangover products available, currently there is no hangover treatment that is supported by substantial scientific evidence demonstrating its efficacy and safety. A pilot study was conducted to investigate the effects...
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JCM, Vol. 9, Pages 958: Mastitis in Autoimmune Diseases: Review of the Literature, Diagnostic Pathway, and Pathophysiological Key Players Journal of Clinical Medicine doi: 10.3390/jcm9040958 Authors: Goulabchand Hafidi Van de Perre Millet Maria Morel Quellec Perrochia Guilpain Mastitis frequently affects women of childbearing age. Of all the pathological breast conditions requiring specific management, autoimmune mastitis is in the third position after...
Mon Mar 30, 2020 03:00
JCM, Vol. 9, Pages 933: Active Helicobacter pylori Infection is Independently Associated with Nonalcoholic Steatohepatitis in Morbidly Obese Patients Journal of Clinical Medicine doi: 10.3390/jcm9040933 Authors: Michael Doulberis Simone Srivastava Stergios A Polyzos Jannis Kountouras Apostolis Papaefthymiou Jolanta Klukowska-Rötzler Annika Blank Aristomenis K Exadaktylos David S Srivastava Nonalcoholic fatty liver disease (NAFLD) emerges as an important global...
Mon Mar 30, 2020 03:00
JCM, Vol. 9, Pages 955: Confusion and Anxiety Following Breast Density Notification: Fact or Fiction? Journal of Clinical Medicine doi: 10.3390/jcm9040955 Authors: Evenda K. Dench Ellie C. Darcey Louise Keogh Kirsty McLean Sarah Pirikahu Christobel Saunders Sandra Thompson Catherine Woulfe Elizabeth Wylie Jennifer Stone In the absence of evidence-based screening recommendations for women with dense breasts, it is important to know if breast density notification...
Mon Mar 30, 2020 03:00
JCM, Vol. 9, Pages 956: IMPA2 Downregulation Enhances mTORC1 Activity and Restrains Autophagy Initiation in Metastatic Clear Cell Renal Cell Carcinoma Journal of Clinical Medicine doi: 10.3390/jcm9040956 Authors: Chia-Hao Kuei Hui-Yu Lin Hsun-Hua Lee Che-Hsuan Lin Jing-Quan Zheng Kuan-Chou Chen Yuan-Feng Lin Although mTOR inhibitors have been approved as first-line therapy for treating metastatic clear cell renal cell carcinoma (ccRCC), the lack of useful markers reduces...
Mon Mar 30, 2020 03:00
JCM, Vol. 9, Pages 957: The Clinical Impact of Hexanic Extract of Serenoa repens in Men with Prostatic Inflammation: A Post Hoc Analysis of a Randomized Biopsy Study Journal of Clinical Medicine doi: 10.3390/jcm9040957 Authors: Michael Samarinas Anastasios Karatzas Vasileios Tzortzis Stavros Gravas A randomized biopsy study showed that hexanic Serenoa repens (HESr) treatment resulted in prostatic inflammation reduction. This post-hoc analysis evaluated the clinical impact of...
Mon Mar 30, 2020 03:00
JCM, Vol. 9, Pages 951: Nuclear Magnetic Resonance Metabolomics Biomarkers for Identifying High Risk Patients with Extranodal Extension in Oral Squamous Cell Carcinoma Journal of Clinical Medicine doi: 10.3390/jcm9040951 Authors: Cheng-Kun Tsai Chien-Yu Lin Chung-Jan Kang Chun-Ta Liao Wan-Ling Wang Meng-Han Chiang Tzu-Chen Yen Gigin Lin Extranodal extension (ENE) is an independent adverse prognostic factor in oral squamous cell carcinoma (OSCC), and is difficult...
Mon Mar 30, 2020 03:00
JCM, Vol. 9, Pages 952: Changes in Respiratory Muscle Strength Following Cardiac Rehabilitation for Prognosis in Patients with Heart Failure Journal of Clinical Medicine doi: 10.3390/jcm9040952 Authors: Hamazaki Kamiya Yamamoto Nozaki Ichikawa Matsuzawa Tanaka Nakamura Yamashita Maekawa Meguro Noda Yamaoka-Tojo Matsunaga Ako Respiratory muscle weakness, frequently observed in patients with heart failure (HF), is reported as a predictor...
Mon Mar 30, 2020 03:00
JCM, Vol. 9, Pages 953: Elevated Lactate Levels in Acute Pulmonary Embolism Are Associated with Prothrombotic Fibrin Clot Properties: Contribution of NETs Formation Journal of Clinical Medicine doi: 10.3390/jcm9040953 Authors: Ząbczyk Natorska Janion-Sadowska Malinowski Janion Undas Background: Elevated plasma lactate levels correlate with high mortality rate in acute pulmonary embolism (PE) patients. We hypothesized that elevated lactate levels correlate with prothrombotic...
Mon Mar 30, 2020 03:00
JCM, Vol. 9, Pages 945: Validation of the mTICCS Score as a Useful Tool for the Early Prediction of a Massive Transfusion in Patients with a Traumatic Hemorrhage Journal of Clinical Medicine doi: 10.3390/jcm9040945 Authors: Klemens Horst Rachel Lentzen Martin Tonglet Ümit Mert Philipp Lichte Christian D. Weber Philipp Kobbe Nicole Heussen Frank Hildebrand The modified Trauma-Induced Coagulopathy Clinical Score (mTICCS) presents a new scoring system for the early...
Mon Mar 30, 2020 03:00
JCM, Vol. 9, Pages 941: Novel Coronavirus Infection (COVID-19) in Humans: A Scoping Review and Meta-Analysis Journal of Clinical Medicine doi: 10.3390/jcm9040941 Authors: Israel Júnior Borges do Nascimento Nensi Cacic Hebatullah Mohamed Abdulazeem Thilo Caspar von Groote Umesh Jayarajah Ishanka Weerasekara Meisam Abdar Esfahani Vinicius Tassoni Civile Ana Marusic Ana Jeroncic Nelson Carvas Junior Tina Poklepovic Pericic Irena Zakarija-Grkovic Silvana...
Mon Mar 30, 2020 03:00
JCM, Vol. 9, Pages 950: Prevalence and Causes of Anemia in Hospitalized Patients: Impact on Diseases Outcome Journal of Clinical Medicine doi: 10.3390/jcm9040950 Authors: Maria Luigia Randi Irene Bertozzi Claudia Santarossa Elisabetta Cosi Fabrizio Lucente Giulia Bogoni Giacomo Biagetti Fabrizio Fabris Anemia is extremely common in hospitalized patients who are old and often with multiple diseases. We evaluated 435 consecutive patients admitted in the internal medicine...
Mon Mar 30, 2020 03:00
JCM, Vol. 9, Pages 954: Acute Kidney Injury Patterns Following Transplantation of Steatotic Liver Allografts Journal of Clinical Medicine doi: 10.3390/jcm9040954 Authors: Caroline Jadlowiec Maxwell Smith Matthew Neville Shennen Mao Dina Abdelwahab Kunam Reddy Adyr Moss Bashar Aqel Timucin Taner Background: Steatotic grafts are increasingly being used for liver transplant (LT); however, the impact of graft steatosis on renal function has not been well described....
Mon Mar 30, 2020 03:00
JCM, Vol. 9, Pages 948: Changes in Office Blood Pressure Control, Augmentation Index, and Liver Steatosis in Kidney Transplant Patients after Successful Hepatitis C Infection Treatment with Direct Antiviral Agents Journal of Clinical Medicine doi: 10.3390/jcm9040948 Authors: Kolonko Musialik Chudek Bartmańska Słabiak-Błaż Kujawa-Szewieczek Kuczera Kwiecień-Furmańczuk Więcek Hepatitis C virus (HCV) infection in kidney transplant recipients (KTRs) can be...
Mon Mar 30, 2020 03:00
JCM, Vol. 9, Pages 946: Clinical Presentations and Outcome Studies of Cranial Nerve Involvement in Herpes Zoster Infection: A Retrospective Single-Center Analysis Journal of Clinical Medicine doi: 10.3390/jcm9040946 Authors: Tsau Liao Hsu Hsu Peng Lin Kuo Ro Varicella-zoster virus (VZV) infection can cause chickenpox and herpes zoster. It sometimes involves cranial nerves, and rarely, it can involve multiple cranial nerves. We aimed to study clinical presentations...
Mon Mar 30, 2020 03:00
JCM, Vol. 9, Pages 949: The Usefulness of Scintigraphic Studies in the Assessment of Asymptomatic Bowel Disease in Patients with Primary Antibody Diseases Journal of Clinical Medicine doi: 10.3390/jcm9040949 Authors: Milito Cinetto Megna Spadaro Quinti Liberatore Enteropathy may be the first presentation of immunodeficiency or it may occur during the course of the disease and in association with malabsorption in patients affected by primary antibody diseases. For...
Mon Mar 30, 2020 03:00
JCM, Vol. 9, Pages 947: GLP-1 Receptor Agonists and Diabetic Kidney Disease: A Call of Attention to Nephrologists Journal of Clinical Medicine doi: 10.3390/jcm9040947 Authors: Górriz Soler Navarro-González García-Carro Puchades D’Marco Castelao Fernández-Fernández Ortiz Górriz-Zambrano Navarro-Pérez Gorgojo-Martinez Type 2 diabetes mellitus (T2DM) represents the main cause of chronic kidney disease (CKD) and end-stage renal disease (ESKD),...
Mon Mar 30, 2020 03:00
JCM, Vol. 9, Pages 942: The Optimal Range of Serum Uric Acid for Cardiometabolic Diseases: A 5-Year Japanese Cohort Study Journal of Clinical Medicine doi: 10.3390/jcm9040942 Authors: Kuwabara Hisatome Niwa Bjornstad Roncal-Jimenez Andres-Hernando Kanbay Johnson Lanaspa The optimal range of serum uric acid (urate) associated with the lowest risk for developing cardiometabolic diseases is unknown in a generally healthy population. This 5-year cohort study...
Mon Mar 30, 2020 03:00
JCM, Vol. 9, Pages 943: Concomitant Intra-Articular Glenohumeral Lesions in Fractures of the Scapula Body Journal of Clinical Medicine doi: 10.3390/jcm9040943 Authors: Zyskowski Pesch Greve Wurm von Matthey Pfeiffer Felix Buchholz Kirchhoff Background: Scapula body fractures are rare injuries with an incidence of 1% of all fractures accounting for 3% to 5% of all upper extremity fractures. Fractures of the scapula commonly result from high-energetic trauma...
Mon Mar 30, 2020 03:00
JCM, Vol. 9, Pages 939: Infectious Esophagitis in Romanian Children: From Etiology and Risk Factors to Clinical Characteristics and Endoscopic Features Journal of Clinical Medicine doi: 10.3390/jcm9040939 Authors: Mădălina Adriana Bordea Alexandru Pîrvan Dan Gheban Ciprian Silaghi Iulia Lupan Gabriel Samașca Lia Pepelea Lia Monica Junie Carmen Costache Objectives. The aim of this study is to provide information about prevalence, etiology, risk factors, clinical...
Mon Mar 30, 2020 03:00
JCM, Vol. 9, Pages 944: A Simulation on Potential Secondary Spread of Novel Coronavirus in an Exported Country Using a Stochastic Epidemic SEIR Model Journal of Clinical Medicine doi: 10.3390/jcm9040944 Authors: Kentaro Iwata Chisato Miyakoshi Ongoing outbreak of pneumonia caused by novel coronavirus (2019-nCoV) began in December 2019 in Wuhan, China, and the number of new patients continues to increase. Even though it began to spread to many other parts of the world, such as other...
Mon Mar 30, 2020 03:00
JCM, Vol. 9, Pages 940: Response of Breast Cancer Cells to PARP Inhibitors Is Independent of BRCA Status Journal of Clinical Medicine doi: 10.3390/jcm9040940 Authors: Man Yee Keung Yanyuan Wu Francesca Badar Jaydutt V. Vadgama Poly (ADP-ribose) polymerase inhibitors (PARPi) have proven to be beneficial to patients with metastatic breast cancer with BRCA1/2 (BReast CAncer type 1 and type 2 genes) mutations. However, certain PARPi in pre-clinical studies have been shown to inhibit...
Mon Mar 30, 2020 03:00
JFMK, Vol. 5, Pages 24: Spine and TMJ: A Pathophysiology Report Journal of Functional Morphology and Kinesiology doi: 10.3390/jfmk5020024 Authors: Fiorillo The relationship between posture, spine, and temporomandibular joint (TMJ) is still a hotly debated topic in medicine. TMJ takes part in different physiological functions of the organism, starting from its embryological development, it is possible that it influences different vital functions. There is a strong connection between...
Mon Mar 30, 2020 03:00
JFMK, Vol. 5, Pages 23: Finding a Balance: A Systematic Review of the Biomechanical Effects of Vestibular Prostheses on Stability in Humans Journal of Functional Morphology and Kinesiology doi: 10.3390/jfmk5020023 Authors: Felix Haxby Mohammad Akrami Reza Zamani The vestibular system is located in the inner ear and is responsible for maintaining balance in humans. Bilateral vestibular dysfunction (BVD) is a disorder that adversely affects vestibular function. This results in symptoms...
Mon Mar 30, 2020 03:00
JFMK, Vol. 5, Pages 22: Brachial Plexus Injuries in Sport Medicine: Clinical Evaluation, Diagnostic Approaches, Treatment Options, and Rehabilitative Interventions Journal of Functional Morphology and Kinesiology doi: 10.3390/jfmk5020022 Authors: Belviso Palermi Sacco Romano Corrado Zappia Sirico The brachial plexus represents a complex anatomical structure in the upper limb. This “network” of peripheral nerves permits the rearrangement of...
Mon Mar 30, 2020 03:00
J. Imaging, Vol. 6, Pages 16: Color Image Complexity versus Over-Segmentation: A Preliminary Study on the Correlation between Complexity Measures and Number of Segments Journal of Imaging doi: 10.3390/jimaging6040016 Authors: Mihai Ivanovici Radu-Mihai Coliban Cosmin Hatfaludi Irina Emilia Nicolae It is said that image segmentation is a very difficult or complex task. First of all, we emphasize the subtle difference between the notions of difficulty and complexity. Then, in...
Mon Mar 30, 2020 03:00
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