Cancers, Vol. 12, Pages 1005: Dysmetabolic Circulating Tumor Cells Are Prognostic in Metastatic Breast Cancer Cancers doi: 10.3390/cancers12041005 Authors: Giulia Brisotto Eva Biscontin Elisabetta Rossi Michela Bulfoni Aigars Piruska Simon Spazzapan Cristina Poggiana Riccardo Vidotto Agostino Steffan Alfonso Colombatti Wilhelm T. S. Huck Daniela Cesselli Rita Zamarchi Matteo Turetta Fabio Del Ben Circulating tumor cells (CTCs)...
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Cancers, Vol. 12, Pages 1004: The Emerging Role of MicroRNAs and Other Non-Coding RNAs in Cancer Cachexia Cancers doi: 10.3390/cancers12041004 Authors: Joana M. O. Santos Sara Peixoto da Silva Rui M. Gil da Costa Rui Medeiros Cancer cachexia or wasting is a paraneoplastic syndrome characterized by systemic inflammation and an involuntary loss of body mass that cannot be reversed by normal nutritional support. This syndrome affects 50%–80% of cancer patients,...
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Cancers, Vol. 12, Pages 1002: Discovery of Pancreatic Adenocarcinoma Biomarkers by Untargeted Metabolomics Cancers doi: 10.3390/cancers12041002 Authors: Ariadna Martín-Blázquez Cristina Jiménez-Luna Caridad Díaz Joaquina Martínez-Galán Jose Prados Francisca Vicente Consolación Melguizo Olga Genilloud José Pérez del Palacio Octavio Caba Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive and lethal cancers, with a 5-year survival...
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Cancers, Vol. 12, Pages 1003: Healthcare Costs of Metastatic Cutaneous Melanoma in the Era of Immunotherapeutic and Targeted Drugs Cancers doi: 10.3390/cancers12041003 Authors: Brenda Leeneman Carin A. Uyl-de Groot Maureen J. B. Aarts Alexander C. J. van Akkooi Franchette W. P. J. van den Berkmortel Alfons J. M. van den Eertwegh Jan Willem B. de Groot Karin H. Herbschleb Jacobus J. M. van der Hoeven Geke A. P. Hospers Ellen Kapiteijn Djura Piersma...
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Cancers, Vol. 12, Pages 1000: Zikavirus prME Envelope Pseudotyped Human Immunodeficiency Virus Type-1 as a Novel Tool for Glioblastoma-Directed Virotherapy Cancers doi: 10.3390/cancers12041000 Authors: Maibritt Kretschmer Patrycja Kadlubowska Daniel Hoffmann Birco Schwalbe Heidi Auerswald Michael Schreiber Glioblastoma multiforme is the most lethal type of brain tumor that is not yet curable owing to its frequent resurgence after surgery. Resistance is mainly...
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Cancers, Vol. 12, Pages 999: Dexamethasone Attenuates X-Ray-Induced Activation of the Autotaxin-Lysophosphatidate-Inflammatory Cycle in Breast Tissue and Subsequent Breast Fibrosis Cancers doi: 10.3390/cancers12040999 Authors: Guanmin Meng Melinda Wuest Xiaoyun Tang Jennifer Dufour Todd P.W. McMullen Frank Wuest David Murray David N. Brindley We recently showed that radiation-induced DNA damage in breast adipose tissue increases autotaxin secretion, production...
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Cancers, Vol. 12, Pages 1001: Ultraweak Photon Emissions as a Non-Invasive, Early-Malignancy Detection Tool: An In Vitro and In Vivo Study Cancers doi: 10.3390/cancers12041001 Authors: Nirosha J. Murugan Michael A. Persinger Lukasz M. Karbowski Blake T. Dotta Early detection of cancer improves treatment options and increases survival. Building upon previous demonstrations that ultraweak photon emissions (UPE) could be measured to detect cancers, we designed an early...
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Cancers, Vol. 12, Pages 998: Impact of Use of Gastric-Acid Suppressants and Oral Anti-Cancer Agents on Survival Outcomes: A Systematic Review and Meta-Analysis Cancers doi: 10.3390/cancers12040998 Authors: Alice Indini Fausto Petrelli Gianluca Tomasello Erika Rijavec Antonio Facciorusso Francesco Grossi Michele Ghidini We performed a systematic review and meta-analysis to evaluate the role of gastric acid suppressant use on outcomes of tyrosine kinase inhibitors...
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Cancers, Vol. 12, Pages 997: Erbb4 Is Required for Cerebellar Developmentand Malignant Phenotype of Medulloblastoma Cancers doi: 10.3390/cancers12040997 Authors: Aldaregia Errarte Olazagoitia-Garmendia Gimeno Uriz Gershon Garcia Matheu Medulloblastoma is the most common and malignant pediatric brain tumor in childhood. It originates from dysregulation of cerebellar development, due to an excessive proliferation of cerebellar granule neuron precursor...
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Cancers, Vol. 12, Pages 995: Effect of Baseline Characteristics on Cabazitaxel Treatment Duration in Patients with Metastatic Castration-Resistant Prostate Cancer: A Post Hoc Analysis of the Compassionate Use/Expanded Access Programs and CAPRISTANA Registry Cancers doi: 10.3390/cancers12040995 Authors: Malik Di Lorenzo Pichler De Giorgi Hitier Ecstein-Fraisse Ozatilgan Carles We examined factors that may impact cabazitaxel treatment duration in...
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Cancers, Vol. 12, Pages 996: Pickled Vegetable and Salted Fish Intake and the Risk of Gastric Cancer: Two Prospective Cohort Studies and a Meta-Analysis Cancers doi: 10.3390/cancers12040996 Authors: Jin Young Yoo Hyun Jeong Cho Sungji Moon Jeoungbin Choi Sangjun Lee Choonghyun Ahn Keun-Young Yoo Inah Kim Kwang-Pil Ko Jung Eun Lee Sue K. Park An increased risk of gastric cancer for pickled vegetable and salted fish intake has been suggested,...
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Cancers, Vol. 12, Pages 993: Depletion of Trichoplein (TpMs) Causes Chromosome Mis-Segregation, DNA Damage and Chromosome Instability in Cancer Cells Cancers doi: 10.3390/cancers12040993 Authors: Angela Lauriola Andrea Martello Sebastian Fantini Gaetano Marverti Tommaso Zanocco-Marani Pierpaola Davalli Daniele Guardavaccaro Sabine Mai Andrea Caporali Domenico D’Arca Mitotic perturbations frequently lead to chromosome mis-segregation that generates...
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Cancers, Vol. 12, Pages 994: Image Analysis Reveals Microstructural and Volumetric Differences in Glioblastoma Patients with and without Preoperative Seizures Cancers doi: 10.3390/cancers12040994 Authors: Stefanie Bette Melanie Barz Huong Ly Nham Thomas Huber Maria Berndt Arthur Sales Friederike Schmidt-Graf Hanno S. Meyer Yu-Mi Ryang Bernhard Meyer Claus Zimmer Jan S. Kirschke Benedikt Wiestler Jens Gempt Purpose: Seizures related...
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Cancers, Vol. 12, Pages 992: Interferon Alpha Therapy Increases Pro-Thrombotic Biomarkers in Patients with Myeloproliferative Neoplasms Cancers doi: 10.3390/cancers12040992 Authors: Dorothée Faille Lamia Lamrani Stéphane Loyau Marie-Geneviève Huisse Marie-Charlotte Bourrienne Sawsaneh Alkhaier Bruno Cassinat Yacine Boulaftali Jérôme Debus Martine Jandrot-Perrus Christine Chomienne Christine Dosquet Nadine Ajzenberg Myeloproliferative...
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Cancers, Vol. 12, Pages 990: Comprehensive Map of the Regulated Cell Death Signaling Network: A Powerful Analytical Tool for Studying Diseases Cancers doi: 10.3390/cancers12040990 Authors: Jean-Marie Ravel L. Cristobal Monraz Gomez Nicolas Sompairac Laurence Calzone Boris Zhivotovsky Guido Kroemer Emmanuel Barillot Andrei Zinovyev Inna Kuperstein The processes leading to, or avoiding cell death are widely studied, because of their frequent perturbation...
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Cancers, Vol. 12, Pages 989: Role of CYP3A5 in Modulating Androgen Receptor Signaling and Its Relevance to African American Men with Prostate Cancer Cancers doi: 10.3390/cancers12040989 Authors: Priyatham Gorjala Rick A. Kittles Oscar B. Goodman Ranjana Mitra Androgen receptor signaling is crucial for prostate cancer growth and is positively regulated in part by intratumoral CYP3A5. As African American (AA) men often carry the wild type CYP3A5 and express high levels...
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Cancers, Vol. 12, Pages 991: Durable Complete Remission and Long-Term Survival in FDG-PET Staged Patients with Stage III Follicular Lymphoma, Treated with Wide-Field Radiation Therapy Cancers doi: 10.3390/cancers12040991 Authors: Michael P. MacManus Rodney J. Hicks Mathias Bressel Belinda A. Campbell Andrew Wirth Gail Ryan H. Miles Prince Max Wolf Rachel Brown John F. Seymour Advanced-stage follicular lymphoma (FL) is generally considered incurable...
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Cancers, Vol. 12, Pages 988: Challenges for Immunotherapy in Multiple Myeloma: Bone Marrow Microenvironment-Mediated Immune Suppression and Immune Resistance Cancers doi: 10.3390/cancers12040988 Authors: Lisa C. Holthof Tuna Mutis The power of immunotherapy in the battle of Multiple Myeloma (MM) started with allogeneic stem cell transplantation, and was rediscovered with immunomodulatory drugs and extended with the outstanding results achieved with targeted antibodies. Today,...
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Cancers, Vol. 12, Pages 986: Identifying Genetic Lesions in Ocular Adnexal Extranodal Marginal Zone Lymphomas of the MALT Subtype by Whole Genome, Whole Exome and Targeted Sequencing Cancers doi: 10.3390/cancers12040986 Authors: Patricia Johansson Ludger Klein-Hitpass Bettina Budeus Matthias Kuhn Chris Lauber Michael Seifert Ingo Roeder Roman Pförtner Martin Stuschke Ulrich Dührsen Anja Eckstein Jan Dürig Ralf Küppers The pathogenesis...
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Cancers, Vol. 12, Pages 987: Ex Vivo Assessment of Tumor-Targeting Fluorescent Tracers for Image-Guided Surgery Cancers doi: 10.3390/cancers12040987 Authors: Fortuné M.K. Elekonawo Jan Marie de Gooyer Desirée L. Bos David M. Goldenberg Otto C. Boerman Lodewijk A.A. Brosens Andreas J.A. Bremers Johannes H.W. de Wilt Mark Rijpkema Image-guided surgery can aid in achieving complete tumor resection. The development and assessment of tumor-targeted imaging...
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Cancers, Vol. 12, Pages 985: p53 and FBXW7: Sometimes Two Guardians Are Worse than One Cancers doi: 10.3390/cancers12040985 Authors: María Galindo-Moreno Servando Giráldez M. Cristina Limón-Mortés Alejandro Belmonte-Fernández Carmen Sáez Miguel Á. Japón Maria Tortolero Francisco Romero Too much of a good thing can become a bad thing. An example is FBXW7, a well-known tumor suppressor that may also contribute to tumorigenesis. Here, we reflect on the results...
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Cancers, Vol. 12, Pages 983: Acquired Immunity Is Not Essential for Radiation-Induced Heart Dysfunction but Exerts a Complex Impact on Injury Cancers doi: 10.3390/cancers12040983 Authors: Rachel A. Schlaak Anne Frei Brian L. Fish Leanne Harmann Tracy Gasperetti Jamie L. Pipke Yunguang Sun Hallgeir Rui Michael J. Flister Benjamin N. Gantner Carmen Bergom While radiation therapy (RT) can improve cancer outcomes, it can lead to radiation-induced...
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Cancers, Vol. 12, Pages 984: Near-Infrared Molecular Imaging of Glioblastoma by Miltuximab®-IRDye800CW as a Potential Tool for Fluorescence-Guided Surgery Cancers doi: 10.3390/cancers12040984 Authors: Dmitry M. Polikarpov Douglas H. Campbell Lucinda S. McRobb Jiehua Wu Maria E. Lund Yanling Lu Sergey M. Deyev Andrew S. Davidson Bradley J. Walsh Andrei V. Zvyagin David A. Gillatt Glioblastoma (GBM) is one of the most aggressive tumors and its...
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NEW EXECUTIVE DIRECTOR ANNOUNCED FOR THE AMERICAN THYROID ASSOCIATION The American Thyroid Association® (ATA®) proudly announces the appointment of Amanda Perl as the organization’s new Executive Director, beginning May 11, 2020. She will succeed Bobbi Smith, who is retiring after 24 years of dedicated and transformative leadership for the ATA. Perl and Smith will work together to transition responsibilities and management of the excellent ATA staff. “A sincere thanks to the selection committee,...
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VideoEndocrinology The Official Journal of: American Thyroid Association FREE ACCESS through April 30, 2020.Watch now: Laparoscopic Left Adrenalectomy for Isolated Adrenal Metastasis of Small Cell Lung Cancer Unresponsive to Cyberknife Radiation Therapy: Case Report Turan Acar, Nihan Acar, and Mehmet Haciyanli Diagnosis of Thyroid Nodule with New Ultrasound Imaging Modalities Ghobad Azizi, Kirk Faust, Michelle L. Mayo, Jessica Farrell, and Carl Malchoff Radiofrequency Ablation SystemizationLeonardo...
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FREE ACCESS to these highlighted articles through March 27, 2020. This month’s issue includes two guest editorials on how the COVID-19 pandemic is impacting the thyroid community. We hope that these perspective pieces will be relevant, helpful, and affirming during this time. We are making these open to the community as it works to ensure that the COVID-19 outbreak is fully understood and contained: COVID-19 and How It Is Affecting Me as a Thyroidologist James V. Hennessey Considerations...
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From Clinical Thyroidology® for the Public: Several recent reports have highlighted a decrease in the quality of life and an increase in depression in some patients with hypothyroidism due to thyroid surgery. Therefore, the authors have examined if there is an association between thyroid surgery and a new onset of depression. Read More… We welcome your feedback and suggestions. Let us know what you want to see in this publication. Feedback & Suggestions The post Clinical Thyroidology<sup>®</sup>...
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Abstract Purpose This scoping review aimed to summarize the current literature on postpartum psychiatric disorders (e.g., postpartum depression, postpartum anxiety, postpartum post-traumatic stress disorder) and the possible relationship of these disorders to the use of pharmacologic labour analgesia (e.g., epidural analgesia, nitrous oxide, parenteral opioids) to identify knowledge gaps that may aid in the planning of future...
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Abstract Purpose Upper airway injury and sympathetic activation may be related to the forces applied during laryngoscopy. We compared the applied forces during laryngoscopy using direct and indirect visualization of a standardized mannequin glottis. Methods Force transducers were applied to the concave surface of a GlideScope T-MAC Macintosh-style...
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