Related Articles Activation of CXCL5-CXCR2 axis promotes proliferation and accelerates G1 to S phase transition of papillary thyroid carcinoma cells and activates JNK and p38 pathways. Cancer Biol Ther. 2019;20(5):608-616 Authors: Cui D, Zhao Y, Xu J Abstract C-X-C motif chemokine ligand 5 (CXCL5) is initially identified to recruit neutrophils by interacting with its receptor, C-X-C motif chemokine receptor 2 (CXCR2). Our prior work demonstrated...
Tue Jul 07, 2020 13:41
Related Articles Rad9a is involved in chromatin decondensation and post-zygotic embryo development in mice. Cell Death Differ. 2019 05;26(5):969-980 Authors: Huang L, Meng TG, Ma XS, Wang ZB, Qi ST, Chen Q, Zhang QH, Liang QX, Wang ZW, Hu MW, Guo L, Ouyang YC, Hou Y, Zhao Y, Sun QY Abstract Zygotic chromatin undergoes extensive reprogramming immediately after fertilization. It is generally accepted that maternal factors control this process....
Tue Jul 07, 2020 13:41
Related Articles Coronavirus disease 2019 communication: novel sign language system to aid surgical tracheostomy whilst wearing a respirator. J Laryngol Otol. 2020 Jun 18;:1-9 Authors: Wilkinson S, Irvine E, Valsamakis T PMID: 32624010 [PubMed - as supplied by publisher]
Tue Jul 07, 2020 17:44
Related Articles A survey of ENT undergraduate teaching in the UK. J Laryngol Otol. 2020 Jun 17;:1-5 Authors: Mayer AW, Smith KA, Carrie S, Collaborative Authors Abstract BACKGROUND: ENT presentations are prevalent in clinical practice but feature little in undergraduate curricula. Consequently, most medical graduates are not confident managing common ENT conditions. In 2014, the first evidence-based ENT undergraduate curriculum was published...
Tue Jul 07, 2020 17:44
Potential of Glucagon-Like Peptide 1 as a Regulator of Impaired Cholesterol Metabolism in the Brain.
Related Articles Potential of Glucagon-Like Peptide 1 as a Regulator of Impaired Cholesterol Metabolism in the Brain. Adv Nutr. 2020 Jul 06;: Authors: Kim YK, Song J Abstract Cerebral vascular diseases are the most common high-mortality diseases worldwide. Their onset and development are associated with glycemic imbalance, genetic background, alteration of atherosclerotic factors, severe inflammation, and abnormal cholesterol metabolism. Recently,...
Tue Jul 07, 2020 17:37
Lithium has been shown to delay the progression of Alzheimer’s disease to reduce the prevalence of dementia. However, its narrow therapeutic index and numerous toxic effects at conventional dosage limited its long-term use to older subjects. Here, we tested the effect of low-dose lithium on cognitive impairment and pathology alterations in a mouse model of Alzheimer’s disease, the amyloid precursor protein/presenilin-1 (APP/PS1) transgenic mouse. We found that both chronic and acute administration...
Fri Jul 03, 2020 03:00
Previous research has demonstrated that some false recognitions are accompanied by retrieval of contexts in which the corresponding semantic associates were presented during the study phase. What kind of neural processes support context retrieval in false recognition? Using functional MRI (fMRI), we tested the hypothesis that context retrieval in false recognition might be supported by brain areas in the core recollection network which also support context retrieval in true recognition. During the...
Fri Jul 03, 2020 03:00
Publication date: Available online 6 July 2020Source: Magnetic Resonance ImagingAuthor(s): Robert V. Bergen, Lawrence Ryner, Marco Essig
Tue Jul 07, 2020 13:30
Publication date: Available online 6 July 2020Source: Magnetic Resonance ImagingAuthor(s): Hampus Olsson, Mads Andersen, Gunther Helms
Tue Jul 07, 2020 13:30
Publication date: September 2020Source: International Immunopharmacology, Volume 86Author(s): Xiuhong Zhang, Yan Zhang, Weizhen Qiao, Ji Zhang, Zhigang Qi
Tue Jul 07, 2020 13:30
Publication date: September 2020Source: International Immunopharmacology, Volume 86Author(s): Miriana d'Alessandro, Felice Perillo, Rosa Metella Refini, Laura Bergantini, Francesca Bellisai, Enrico Selvi, Paolo Cameli, Stefania Manganelli, Edoardo Conticini, Luca Cantarini, Piersante Sestini, Bruno Frediani, Elena Bargagli
Tue Jul 07, 2020 13:30
Related Articles The role of Narrow Band Imaging (NBI) in the diagnosis of sinonasal diseases. Rhinology. 2020 Jul 06;: Authors: Bruno C, Fiori GM, Locatello LG, Cannavicci A, Gallo O, Maggiore G Abstract BACKGROUND: Narrow band imaging (NBI) endoscopy is an optical method that helps to characterise tissue vasculature. Its appli- cation in sinonasal pathology remains scarce and a systematic study of its application to rhinology is lacking. The...
Tue Jul 07, 2020 15:30
Related Articles Self-reported alteration of sense of smell or taste in patients with COVID-19: a systematic review and meta-analysis on 3563 patients. Rhinology. 2020 Jul 06;: Authors: Borsetto D, Hopkins C, Philips V, Obholzer R, Tirelli G, Polesel J, Calvanese L, Boscolo-Rizzo P Abstract BACKGROUND: Emerging reports suggest that new onset of smell or taste loss are potential early clinical markers of SARS-CoV-2 infection, but it remains unclear...
Tue Jul 07, 2020 15:30
Due to their ability in self-renewing and differentiation into a wide variety of tissues, mesenchymal stem cells (MSCs) exhibit outstanding potential for regenerative medicine. This study was aimed at investigating different aspects of MSC therapy in controlling hyperglycemia in streptozotocin-induced diabetes rats. Using an islet cell differentiation protocol, bone marrow (BM) MSCs were differentiated into insulin-producing cells (IPCs). The differentiation process was evaluated by immunocytochemistry,...
Tue Jul 07, 2020 08:54
Publication date: November 2020Source: Medical Hypotheses, Volume 144Author(s): Dipankar Bhattacharyya
Tue Jul 07, 2020 13:21
Publication date: November 2020Source: Medical Hypotheses, Volume 144Author(s): Silvia Marino, Martino Ruggieri, Raffaele Falsaperla
Tue Jul 07, 2020 13:21
Publication date: November 2020Source: Medical Hypotheses, Volume 144Author(s): Omer Ć. Ibrahimagić, Amra Iljazović, Suljo Kunić, Vesna Vržuljević, Aida Šehanović, Larisa Kovačević, Leila Avdić
Tue Jul 07, 2020 13:21
Related Articles Effect of Chin-down-plus-larynx-tightening maneuver on swallowing function after minimally invasive esophagectomy: A randomized controlled trail. Cancer Med. 2020 Jul 06;: Authors: Yang F, Zou L, Li L, Zou Q, Chen P, Sun H, Liu X, Xu X Abstract BACKGROUND: The incidence of swallowing abnormality was high after minimally invasive esophagectomy (MIE) for esophageal cancer (EC). Few reports, however, focused on interventions for...
Tue Jul 07, 2020 17:21
Related Articles T1b Glottic Tumor and Anterior Commissure Involvement: Is the Transoral CO2 Laser Microsurgery a Safe Option? Ear Nose Throat J. 2020 Jul 05;:145561320937238 Authors: Cabrera-Sarmiento JA, Vázquez-Barro JC, Herranz González-Botas J, Chiesa-Estomba C, Mayo-Yáñez M Abstract OBJECTIVES: Transoral CO2 laser therapy represents the treatment of choice for early-stage laryngeal tumors. The anterior commissure involvement (ACI) is related...
Tue Jul 07, 2020 17:21
Related Articles KTP Laser Treatment of Early Glottic Cancer: A Multi-Institutional Retrospective Study. Ann Otol Rhinol Laryngol. 2020 Jul 04;:3489420938100 Authors: Parker NP, Weidenbecher MS, Friedman AD, Walker BA, Lott DG Abstract OBJECTIVES: The primary objectives were to report oncologic outcomes of transoral laser microsurgery with potassium-titanyl-phosphate (KTP) laser (TLM-KTP) ablation of early glottic cancer (EGC). The secondary...
Tue Jul 07, 2020 17:21
Related Articles Spinal muscular atrophy and Farber disease due to ASAH1 variants: A case report. Am J Med Genet A. 2020 Jul 05;: Authors: Lee BH, Mongiovi P, Levade T, Marston B, Mountain J, Ciafaloni E Abstract Genetic variations in the ASAH1 gene are associated with a spectrum of disorders ranging from Farber disease (FD) to spinal muscular atrophy with or without progressive myoclonic epilepsy (SMA-PME). FD presents most commonly in infants...
Tue Jul 07, 2020 17:21
Related Articles Subglottic Stenosis: Development of a Clinically Relevant Endoscopic Animal Model. Otolaryngol Head Neck Surg. 2020 06;162(6):905-913 Authors: Mady LJ, Criado M, Park J, Baddour K, Aral AM, Roy A, Rigatti LH, Kumta PN, Chi DH Abstract OBJECTIVE: Develop a clinically relevant and reproducible endoscopic animal model for subglottic stenosis amenable to testing of minimally invasive therapeutic modalities. STUDY DESIGN:...
Tue Jul 07, 2020 13:16
Related Articles Pilot Study to Assess the Use of Ultrasound in Evaluating the Abnormal Pediatric Airway. Otolaryngol Head Neck Surg. 2020 Jun;162(6):950-953 Authors: Bell JR, Cohen AP, Graff JT, Fleck RJ, O'Hara S, de Alarcon A, Hart CK Abstract In this study, we sought to explore the feasibility of using ultrasonography to evaluate airway anomalies in awake children with previous airway reconstruction. For the month of December 2018, we reviewed...
Tue Jul 07, 2020 13:16
Related Articles Neurons in the Intermediate Reticular Nucleus Coordinate Postinspiratory Activity, Swallowing, and Respiratory-Sympathetic Coupling in the Rat. J Neurosci. 2019 12 04;39(49):9757-9766 Authors: Toor RUAS, Sun QJ, Kumar NN, Le S, Hildreth CM, Phillips JK, McMullan S Abstract Breathing results from sequential recruitment of muscles in the expiratory, inspiratory, and postinspiratory (post-I) phases of the respiratory cycle. Here...
Tue Jul 07, 2020 13:16
Related Articles The prognostic value of CT-based image-biomarkers for head and neck cancer patients treated with definitive (chemo-)radiation. Oral Oncol. 2019 08;95:178-186 Authors: Zhai TT, Langendijk JA, van Dijk LV, Halmos GB, Witjes MJH, Oosting SF, Noordzij W, Sijtsema NM, Steenbakkers RJHM Abstract OBJECTIVES: The aim of this study was to investigate whether quantitative CT image-biomarkers (IBMs) can improve the prediction models...
Tue Jul 07, 2020 13:16
Related Articles Induction chemotherapy in head and neck cancers: Results and controversies. Oral Oncol. 2019 08;95:164-169 Authors: Gau M, Karabajakian A, Reverdy T, Neidhardt EM, Fayette J Abstract Standard treatment for locally advanced head and neck squamous cell carcinoma (LAHNSCC) consists mainly of concurrent chemoradiation (CCR) but induction chemotherapy (IC) by docetaxel-cisplatin-fluorouracil (TPF), followed by CCR, is a strong option....
Tue Jul 07, 2020 13:16
Related Articles Laryngo-esophageal dysfunction free survival and propensity score matched analysis comparing organ preservation and total laryngectomy in hypopharynx cancer. Oral Oncol. 2019 08;95:143-149 Authors: Petersen JF, Arends CR, van der Noort V, Al-Mamgani A, de Boer JP, Stuiver MM, van den Brekel MWM Abstract AIMS: To assess the functional outcomes of patients treated for hypopharynx cancer and to obtain an unbiased estimate of survival...
Tue Jul 07, 2020 13:16
Related Articles The epg5 knockout zebrafish line: a model to study Vici syndrome. Autophagy. 2019 08;15(8):1438-1454 Authors: Meneghetti G, Skobo T, Chrisam M, Facchinello N, Fontana CM, Bellesso S, Sabatelli P, Raggi F, Cecconi F, Bonaldo P, Dalla Valle L Abstract The EPG5 protein is a RAB7A effector involved in fusion specificity between autophagosomes and late endosomes or lysosomes during macroautophagy/autophagy. Mutations in the human...
Tue Jul 07, 2020 13:16
Related Articles Gasping for a Diagnosis: Pediatric Vocal Cord Dysfunction. J Pediatr Health Care. 2019 Jan;33(1):5-13 Authors: Wenzel M Abstract Vocal cord dysfunction is an obstruction of the upper airway, primarily on inspiration, due to the paradoxical adduction of the vocal cords. Vocal cord dysfunction continues to be underdiagnosed as its own entity. The lack of diagnosis can be attributed to the overlap of symptoms between asthma and...
Tue Jul 07, 2020 13:16
Related Articles Modulation of information processing by AMPA receptor auxiliary subunits. J Physiol. 2020 Jul 06;: Authors: Jacobi E, von Engelhardt J Abstract AMPA-type glutamate receptors (AMPARs) are key molecules of neuronal communication in our brain. The discovery of AMPAR auxiliary subunits, such as proteins of the TARP, CKAMP, and CNIH families, fundamentally changed our understanding of how AMPAR function is regulated. Auxiliary subunits...
Tue Jul 07, 2020 17:15
Related Articles Clash of the cascades: Release the inhibition. J Physiol. 2020 Jul 06;: Authors: Currier BS, Joanisse S, McKendry J PMID: 32628271 [PubMed - as supplied by publisher]
Tue Jul 07, 2020 17:15
Related Articles Paracellular bicarbonate flux across human cystic fibrosis airway epithelia tempers changes in airway surface liquid pH. J Physiol. 2020 Jul 05;: Authors: Thornell IM, Rehman T, Pezzulo AA, Welsh MJ Abstract KEY POINTS: Cl- and HCO3 - had similar paracellular permeabilities in human airway epithelia. PCl /PNa of airway epithelia was unaltered by pH 7.4 vs. pH 6.0 solutions. Under basal conditions, calculated paracellular HCO3...
Tue Jul 07, 2020 17:15
Related Articles Obligatory role for PKCδ in PIP2 -mediated activation of store-operated TRPC1 channels in vascular smooth muscle cells. J Physiol. 2020 Jul 06;: Authors: Martín-Aragón Baudel MAS, Shi J, Large WA, Albert AP Abstract KEY POINTS: In vascular smooth muscle cells (VSMCs), activation of Ca2+ -permeable store-operated channels (SOCs) composed of canonical transient receptor potential channel 1 (TRPC1) subunits mediate Ca2+ entry pathways...
Tue Jul 07, 2020 17:15
Related Articles Anterior reduction and fusion for acute unilateral cervical facet dislocation without severe spinal cord injuries. J Clin Neurosci. 2020 Jul 02;: Authors: Ren C, Qin R, Li Y, Wang P Abstract PURPOSE: This study aimed to evaluate safety and effectiveness of simple anterior reduction and fusion for acute lower cervical unilateral facet dislocation without severe spinal cord injuries. MATERIALS AND METHODS: One hundred...
Tue Jul 07, 2020 17:13
Related Articles Sepsis after elective neurosurgery: Incidence, outcomes, and predictive factors. J Clin Neurosci. 2020 Jul 02;: Authors: Pertsch NJ, Tang OY, Seicean A, Toms SA, Weil RJ Abstract Sepsis is a life-threatening condition resulting from systemic infection, with mortality rates approaching 30%. Most neurological surgeries are now performed electively, which permits medical optimization preoperatively. We performed a retrospective...
Tue Jul 07, 2020 17:13
A comparison of three platelet function tests in ischemic stroke patients with antiplatelet therapy.
Related Articles A comparison of three platelet function tests in ischemic stroke patients with antiplatelet therapy. J Clin Neurosci. 2020 Jul 02;: Authors: Shao T, Cheng Y, Jin J, Huang L, Yang D, Luo C, Han Z, Wang Z, Ge W, Xu Y Abstract Predicting the effectiveness of antiplatelet drugs is critical to precision antiplatelet therapy. However, there is a lack of an acceptable method, although there are a variety of methods for detecting platelet...
Tue Jul 07, 2020 17:13
Related Articles Could self-locking stand-alone cage reduce adjacent-level ossification development after aneterior cervical discectomy and fusion? J Clin Neurosci. 2020 Jul 02;: Authors: Zhou J, Li J, Lin H, Li X, Dong J, Zhou X Abstract Numerous studies have shown that cervical arthrodesis is associated with the adjacent-segment pathology (ASP), such as adjacent-level ossification development (ALOD). However, it still remains largely unclear...
Tue Jul 07, 2020 17:13
Abstract Systemic Sclerosis (SSc) is a severe disease whose pathophysiology remains partly unknown, combining auto‐immune, vascular and fibrotic features. Recently, we evidenced a link between vasculopathy and pigmentary changes in SSc. CCN3 (NOV) is a matricellular protein implicated both in angiogenesis and pigmentation regulation, in particular melanocyte adhesion to the basal layer. We decided to study CCN3 expression in SSc epidermis. We show that in SSc patients with pigmentary changes compared...
Mon Jul 06, 2020 21:59
Publication date: Available online 6 July 2020Source: Reports of Practical Oncology & RadiotherapyAuthor(s): María-Ester Brandan, Alejandro Rodríguez-Laguna
Tue Jul 07, 2020 13:08
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