Publication date: Available online 6 July 2020Source: Journal of Surgical EducationAuthor(s): Zakir Haider, Alistair Hunter
Tue Jul 07, 2020 18:43
Publication date: Available online 6 July 2020Source: Journal of Surgical EducationAuthor(s): Robert Naples, Thomas H. Shin, Judith C. French, Jeremy M. Lipman
Tue Jul 07, 2020 18:43
Publication date: Available online 6 July 2020Source: Journal of Surgical EducationAuthor(s): Kyla P. Terhune, Jennifer Choi, John M. Green, Amy N. Hildreth, Jeremy M. Lipman, Cary B. Aarons, Donna A. Heyduk, Subhasis Misra, Rahul J. Anand, Thomas F. Fise, Catherine B. Thorne, Gretchen C. Edwards, Amit R.T. Joshi, Clarence E. Clark, Valentine N. Nfonsam, Alfred Chahine, Douglas S. Smink, Benjamin T. Jarman, David T. Harrington
Tue Jul 07, 2020 18:43
Publication date: Available online 6 July 2020Source: Journal of Surgical EducationAuthor(s): Neil N. Luu, Christina M. Yver, Jennifer E. Douglas, Kendall K. Tasche, Punam G. Thakkar, Karthik Rajasekaran
Tue Jul 07, 2020 18:43
Publication date: Available online 6 July 2020Source: Journal of Surgical EducationAuthor(s): Nicole Wing Lam Hon, Nabil Hussein, Osami Honjo, Shi-Joon Yoo
Tue Jul 07, 2020 18:43
Designing a National Curriculum to Advance Surgical Oncology in Mozambique: A Delphi Consensus Study
Publication date: Available online 6 July 2020Source: Journal of Surgical EducationAuthor(s): Atílio Morais, Manuel Simão, Matchecane Cossa, Jotamo Come, Carlos Selemane, Adriano Tivane, Satish Tulsidás, Cesaltina Lorenzoni, Jéssica Rodrigues, Luís Antunes, Donzilia Brito, Manuel João Costa, Moshin Sidat, Maria do Rosário O Martins, Lúcio Lara Santos
Tue Jul 07, 2020 18:43
Publication date: Available online 6 July 2020Source: Brain Research BulletinAuthor(s): Zuotian Wu, Gaohua Wang, Ling Xiao, Yanyan Wei, Huiling Wang, Lin Zhou, Limin Sun
Tue Jul 07, 2020 18:32
Mucosal Immunology, Published online: 07 July 2020; doi:10.1038/s41385-020-0318-2IL-17A both initiates, via IFNγ suppression, and limits the pulmonary type-2 immune response to nematode infection
Tue Jul 07, 2020 03:00
Tue Jul 07, 2020 03:00
Publication date: September 2020Source: Acta Histochemica, Volume 122, Issue 6Author(s): Mahtab Teimouri, Mohammad Hassan Heidari, Abdollah Amini, Yousef Sadeghi, Mohammad-Amin Abdollahifar, Abbas Aliaghaei, Ali Khavanin, Farshad Nadri, Samira Danyali, Tayebeh Sanchooli
Tue Jul 07, 2020 18:13
Publication date: Available online 7 July 2020Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Cheryl A. Steiman, Michael D. Evans, Kristine E. Lee, Michael R. Lasarev, Ronald E. Gangnon, Brent F. Olson, Kathrine L. Barnes, Casper G. Bendixsen, Christine M. Seroogy, James E. Gern
Tue Jul 07, 2020 18:12
Related Articles [COVID-19 and hematopoietic stem cell transplantation: Recommendations]. Bull Cancer. 2020 Jun 20;: Authors: Toughza J, Agadr A, Ismaili N PMID: 32624167 [PubMed - as supplied by publisher]
Tue Jul 07, 2020 18:11
Zusammenfassung Weltweit steigt die Inzidenz von mit dem humanen Papillomavirus (HPV) assoziierten Oropharynxkarzinomen. Aufgrund eines deutlich unterschiedlichen Therapieansprechens gegenüber HPV-negativen Oropharynxkarzinomen kann die Festlegung des idealen therapeutischen Ansatzes eine Herausforderung darstellen. HPV-positive Oropharynxkarzinome zeigen insbesondere bei Nierauchern ein gutes Ansprechen auf eine primäre Strahlentherapie, und Studien bieten zugleich Hinweise auf...
Tue Jul 07, 2020 03:00
Abstract Background Several studies have demonstrated a significant benefit of neuromuscular facial training in the rehabilitation of patients with facial palsy. However, printed instructions for home training are often not of optimum quality and associated with low adherence to therapy. Professional guidance, e.g., by occupational therapists, is regarded as being of high quality, but is associated with a high cost burden, particularly...
Tue Jul 07, 2020 03:00
Publication date: September 2020Source: Neoplasia, Volume 22, Issue 9Author(s): Qin Yang, Cancan Zhang, Yuan Ren, Huan Yi, Tianjiao Luo, Fangliang Xing, Xuefeng Bai, Lining Cui, Linyan Zhu, Jun Ouyang, Pengcheng Jiang, Weirong Fan, Jianping Qiu, Fengmian Wang, Xin Xing, Zhigang Zhang, Xueli Zhang, Rong Zhang
Tue Jul 07, 2020 18:06
Publication date: September 2020Source: Neoplasia, Volume 22, Issue 9Author(s): Rami Mäkelä, Antti Arjonen, Aldwin Suryo Rahmanto, Ville Härmä, Janne Lehtiö, Teijo Kuopio, Thomas Helleday, Olle Sangfelt, Juha Kononen, Juha K. Rantala
Tue Jul 07, 2020 18:06
Abstract Compensatory hypertrophy (CH) occurs due to excessive mechanical load on a muscle, promoting an increase in the size of muscle fibers. In clinical practice, situations such as partial nerve injuries, denervation, and muscle imbalance caused by trauma to muscles and nerves or diseases that promote the loss of nerve conduction can induce CH in muscle fibers. Photobiomodulation (PBM) has demonstrated beneficial effects on muscle tissue during CH. The aim of the present study...
Tue Jul 07, 2020 03:00
Abstract The aim of this study was to compare the efficacy of low-level laser treatment (LLLT) and extracorporeal shock wave therapy (ESWT) in the treatment of subacromial impingement syndrome (SIS). Seventy-one patients with subacromial impingement were randomly assigned to LLLT (n = 37) and ESWT (n = 34) groups. The patients received a total of 15 sessions of LLLT or once a week for 3 sessions of ESWT. All patients, before treatment, at the end of treatment, and 3 months after...
Tue Jul 07, 2020 03:00
Runx proteins are bifunctional transcription factors that both repress and activate transcription in animal cells. Typically, Runx proteins work in concert with other transcriptional regulators, including co-activators and co-repressors to mediate their biological effects. In Drosophila melanogaster the archetypal Runx protein, Runt, functions in numerous processes including segmentation, neurogenesis and sex determination. During primary sex determination Runt acts as one of four X-linked signal...
Tue Jul 07, 2020 16:31
The fungus Metarhizium anisopliae is a facultative insect pathogen used as biological control agent of several agricultural pests worldwide. It is a dimorphic fungus that is able to display two growth morphologies, a filamentous phase with formation of hyphae and a yeast-like phase with formation of single-celled blastospores. Blastospores play an important role for M. anisopliae pathogenicity during disease development. They are formed solely in the hemolymph of infected insects as a fungal strategy...
Tue Jul 07, 2020 16:31
Circular RNA (circRNA) is a covalently-closed single-stranded RNA molecule that plays an important role in transcriptional regulation of gene expression in a variety of species. Light intensity is a pivotal environmental factor affecting plant growth and development. However, little is known regarding photoresponsive plant circRNAs. Here, we aimed to investigate the expression and function of circRNAs in lettuce leaves in response to different light intensity treatments. We performed RNA sequencing...
Tue Jul 07, 2020 16:31
Salmonella are a type of bacteria known to cause food-borne illness. Their host range varies widely, and their susceptibility to the host determines its pathogenicity. Salmonella enterica serovar Rissen (S. Rissen) is a widely distributed serotype; however, its virulence and pathogenicity are poorly understood. In this study, the pathogenicity and antibiotic resistance of a representative S. Rissen isolate were investigated. The cell model results showed that S. Rissen preferred to replicate in human...
Tue Jul 07, 2020 16:31
Ascochyta rabiei is the causal organism of ascochyta blight of chickpea and is present in chickpea crops worldwide. Here we report the release of a high-quality PacBio genome assembly for the Australian A. rabiei isolate ArME14. We compare the ArME14 genome assembly with an Illumina assembly for Indian A. rabiei isolate, ArD2. The ArME14 assembly has gapless sequences for nine chromosomes with telomere sequences at both ends and 13 large contig sequences that extend to one telomere. The total length...
Tue Jul 07, 2020 16:31
The nucleosome is the primary unit of chromatin structure and commonly imputed as a regulator of nuclear events, although the exact mechanisms remain unclear. Recent studies have shown that certain nucleosomes can have different sensitivities to micrococcal nuclease (MNase) digestion, resulting in the release of populations of nucleosomes dependent on the concentration of MNase. Mapping MNase sensitivity of nucleosomes at transcription start sites genome-wide reveals an important functional nucleosome...
Tue Jul 07, 2020 16:31
Modern crop breeding is in constant demand for new genetic diversity as part of the arms race with genetic gain. The elite gene pool has limited genetic variation and breeders are trying to introduce novelty from unadapted germplasm, landraces and wild relatives. For polygenic traits, currently available approaches to introgression are not ideal, as there is a demonstrable bias against exotic alleles during selection. Here, we propose a partitioned form of genomic selection, called Origin Specific...
Tue Jul 07, 2020 16:31
Ever decreasing costs along with advances in sequencing and library preparation technologies enable even small research groups to generate chromosome-level assemblies today. Here we report the generation of an improved chromosome-level assembly for the Siamese fighting fish (Betta splendens) that was carried out during a practical university master’s course. The Siamese fighting fish is a popular aquarium fish and an emerging model species for research on aggressive behavior. We updated the current...
Tue Jul 07, 2020 16:31
Plasma concentration of Cystatin C (CysC) level is a biomarker of glomerular filtration rate in the kidney. We use a Systems Genetics approach to investigate the genetic determinants of plasma CysC concentration. To do so we perform Quantitative Trait Loci (QTL) and expression QTL (eQTL) analysis of 120 Diversity Outbred (DO) female mice, 56 weeks of age. We performed network analysis of kidney gene expression to determine if the gene modules with common functions are associated with kidney biomarkers...
Tue Jul 07, 2020 16:31
Anopheles sinensis is a major malaria vector in Southeast Asia. Resistance to pyrethroid insecticides in this species has impeded malaria control in the region. Previous studies found that An. sinensis populations from Yunnan Province, China were highly resistant to deltamethrin and did not carry mutations in the voltage-gated sodium channel gene that cause knockdown resistance. In this study, we tested the hypothesis that other genomic variants are associated with the resistance phenotype. Using...
Tue Jul 07, 2020 16:31
Gene introgression from wild species has been shown to be a feasible approach for fiber quality improvement in Upland cotton. Previously, we developed an interspecific G. mustelinum x G. hirsutum advanced-backcross population and mapped over one hundred QTL for fiber quality traits. In the current study, a trait-based selective genotyping approach was utilized to prioritize a small subset of introgression lines with high phenotypic values for different fiber quality traits, to simultaneously validate...
Tue Jul 07, 2020 16:31
The heterogeneous stock (HS) is an outbred rat population derived from eight inbred rat strains. HS rats are ideally suited for genome wide association studies; however, only a few genotyping microarrays have ever been designed for rats and none of them are currently in production. To address the need for an efficient and cost effective method of genotyping HS rats, we have adapted genotype-by-sequencing (GBS) to obtain genotype information at large numbers of single nucleotide polymorphisms (SNPs)....
Tue Jul 07, 2020 16:31
Lung adenocarcinoma (LUAD) is one of the most common malignant tumors. How to effectively diagnose LUAD at an early stage and make an accurate judgement of the occurrence and progression of LUAD are still the focus of current research. Support vector machine (SVM) is one of the most effective methods for diagnosing LUAD of different stages. The study aimed to explore the dynamic change of differentially expressed genes (DEGs) in different stages of LUAD, and to assess the risk of LUAD through DEGs...
Tue Jul 07, 2020 16:31
Nutrition is a major factor influencing many aspects of Drosophila melanogaster physiology. However, a wide range of diets, many of which are termed "standard" in the literature, are utilized for D. melanogaster research, leading to inconsistencies in reporting of nutrition-dependent phenotypes across the field. This is especially evident in microbiome studies, as diet has a pivotal role in microbiome composition and resulting host-microbe interactions. Here, we performed a meta-analysis of diets...
Tue Jul 07, 2020 16:31
Miscanthus is a perennial grass with potential for lignocellulosic ethanol production. To ensure its utility for this purpose, breeding efforts should focus on increasing genetic diversity of the nothospecies Miscanthus x giganteus (Mxg) beyond the single clone used in many programs. Germplasm from the corresponding parental species M. sinensis (Msi) and M. sacchariflorus (Msa) could theoretically be used as training sets for genomic prediction of Mxg clones with optimal genomic estimated breeding...
Tue Jul 07, 2020 16:31
Blood cells, known as hemocytes in invertebrates, play important and conserved roles in immunity, wound healing and tissue remodelling. The control of hemocyte number is therefore critical to ensure these functions are not compromised, and studies using Drosophila melanogaster are proving useful for understanding how this occurs. Recently, the embryonic patterning gene, torso-like (tsl), was identified as being required both for normal hemocyte development and for providing immunity against certain...
Tue Jul 07, 2020 16:31
Egg-laying behavior in Caenorhabditis elegans is a well-known model for investigating fundamental cellular processes. In egg-laying, muscle contraction is the relaxation of the vulval muscle to extrude eggs from the vulva. Unlike skeletal muscle, vulval muscle lacks visible striations of the sarcomere. Therefore, vulval muscle must counteract the mechanical stress, caused by egg extrusion and body movement, from inducing cell-shape distortion by maintaining its cytoskeletal integrity. However, the...
Tue Jul 07, 2020 16:31
Over the past few decades, obesity has become a public health issue of global concern. Even though disparities exist between human populations, e.g., the higher liver fat content of the Japanese despite a lower body mass index (BMI), studies on the genetics of obesity still largely focus on populations of European descent, leading to a dearth of genetic data on non-European populations. In this context, this study aimed to establish a broad picture of the genetic attributes of the Japanese population,...
Tue Jul 07, 2020 16:31
It is well known that mammals and avian gut microbiota compositions are shaped by the host genomes and affect quantitative traits. The microbial architecture describes the impact of the microbiota composition on quantitative trait variation and the number and effect distribution of microbiota features. In the present study the gut microbial architecture of feed-related traits phosphorus and calcium utilization, daily gain, feed intake and feed per gain ratio in the domestic poultry model species...
Tue Jul 07, 2020 16:31
Bread wheat (Triticum aestivum L.) is one of the world’s most important crops. Maintaining wheat yield gains across all of its major production areas is a key target toward underpinning global food security. Brazil is a major wheat producer in South America, generating grain yields of around 6.8 million tons per year. Here, we establish and genotype a wheat association mapping resource relevant to contemporary Brazilian wheat breeding programs. The panel of 558 wheat accessions was genotyped using...
Tue Jul 07, 2020 16:31
Neuroblast migration is a critical aspect of nervous system development (e.g., neural crest migration). In an unbiased forward genetic screen, we identified a novel player in neuroblast migration, the ETR-1/CELF1 RNA binding protein. CELF1 RNA binding proteins are involved in multiple aspects of RNA processing including alternative splicing, stability, and translation. We find that a specific mutation in alternatively-spliced exon 8 results in migration defects of the AQR and PQR neurons, and not...
Tue Jul 07, 2020 16:31
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