Related Articles A Pilot, Phase II, Randomized, Open-Label Clinical Trial Comparing the Neurotoxicity of Three Dose Regimens of Nab-Paclitaxel to That of Solvent-Based Paclitaxel as the First-Line Treatment for Patients with Human Epidermal Growth Factor Receptor Type 2-Negative Metastatic Breast Cancer. Oncologist. 2019 11;24(11):e1024-e1033 Authors: Ciruelos E, Apellániz-Ruiz M, Cantos B, Martinez-Jáñez N, Bueno-Muiño C, Echarri MJ, Enrech S, Guerra JA, Manso...
Thu Jul 02, 2020 13:18
Related Articles Radiological features and outcomes of combined hepatocellular-cholangiocarcinoma in patients undergoing surgical resection. J Formos Med Assoc. 2020 Jan;119(1 Pt 1):125-133 Authors: Chi CT, Chau GY, Lee RC, Chen YY, Lei HJ, Hou MC, Chao Y, Huang YH Abstract BACKGROUND/PURPOSE: Combined hepatocellular-cholangiocarcinoma (cHCC-CCA) is a rare primary liver cancer. Preoperative diagnosis of cHCC-CCA is difficult, and outcome of...
Thu Jul 02, 2020 13:18
Related Articles Successful treatment of a BRAF V600E-mutant extracranial metastatic anaplastic oligoastrocytoma with vemurafenib and everolimus. Cancer Biol Ther. 2019;20(4):431-434 Authors: Shi L, Zou Z, Ding Q, Liu Q, Zhou H, Hong X, Peng G Abstract BACKGROUND: Extracranial metastasis is a rare phenomenon of anaplastic oligoastrocytoma. When patients progress after comprehensive treatment, there is often no effective treatment. Rapid development...
Thu Jul 02, 2020 13:18
Related Articles New onset acute promyelocytic Leukemia during pregnancy: report of 2 cases. Cancer Biol Ther. 2019;20(4):397-401 Authors: Li H, Han C, Li K, Li J, Wang Y, Xue F Abstract Acute promyelocytic leukemia (APL) is one of the most fatal hematological malignancies. APL during pregnancy is a rare comorbidity and can lead to adverse outcomes, such as maternal and/or fetal death, without timely and appropriate management. Medical management...
Thu Jul 02, 2020 13:18
Related Articles Bone marrow washout for multilevel vertebroplasty in multiple myeloma spinal involvement. Technical note. Eur Spine J. 2019 06;28(6):1455-1460 Authors: Hershkovich O, Lucantoni C, Kapoor S, Boszczyk B Abstract INTRODUCTION: Vertebral involvement is found in a high percentage of multiple myeloma (MM) patients, often requiring multilevel surgical treatment to reduce pain and disability and to receive prompt access to oncological...
Thu Jul 02, 2020 13:18
Related Articles Malignant triton tumor: Grand Round presentation of a rare aggressive case thoracolumbar spine tumor. Eur Spine J. 2019 06;28(6):1448-1452 Authors: Ghailane S, Fauquier S, Lepreux S, Le Huec JC Abstract INTRODUCTION: We report a rare and aggressive case of malignant triton tumor (MTT) at the thoracolumbar junction with foraminal extension mistreated as schwannoma. MATERIALS AND METHODS: A 70-year-old man with a 2-year...
Thu Jul 02, 2020 13:18
Abstract Background SARS‐CoV‐2 coronavirus infection ranges from asymptomatic through to fatal COVID‐19 characterised by a “cytokine storm” and lung failure. Vitamin D deficiency has been postulated as a determinant of severity. Objectives To review the evidence relevant to vitamin D and COVID‐19 Methods Narrative review Results Regression modelling shows that more northerly countries in the Northern Hemisphere are currently (May 2020) showing relatively high COVID‐19 mortality,...
Thu Jul 02, 2020 11:12
Abstract Background Hypertensive nephrosclerosis is the presumed underlying cause in many end stage kidney disease (ESKD) patients, but the diagnosis is disputed and based on clinical criteria with low diagnostic accuracy. Objective To evaluate and improve the diagnostic process for nephrosclerosis patients. Methods We included adults from the population‐based HUNT study (n=50,552), Norwegian CKD patients referred for kidney biopsy 1988‐2012 (n=7,261), and unselected...
Thu Jul 02, 2020 22:00
Related Articles The Influence of Hearing Loss on Cognitive Control in an Auditory Conflict Task: Behavioral and Pupillometry Findings. J Speech Lang Hear Res. 2020 Jul 01;:1-10 Authors: Zekveld AA, van Scheepen JAM, Versfeld NJ, Kramer SE, van Steenbergen H Abstract Purpose The pupil dilation response is sensitive not only to auditory task demand but also to cognitive conflict. Conflict is induced by incompatible trials in auditory Stroop...
Thu Jul 02, 2020 13:07
Related Articles Identification of Perinatal Risk Factors for Auditory Neuropathy Spectrum Disorder. Laryngoscope. 2020 Jul 01;: Authors: West AN, Kuan EC, Peng KA Abstract OBJECTIVES/HYPOTHESIS: To identify medical risk factors associated with auditory neuropathy spectrum disorder (ANSD). STUDY DESIGN: Retrospective case-control study. METHODS: During a 2-year period (2013-2014) patients with newly diagnosed ANSD were...
Thu Jul 02, 2020 13:07
Related Articles A Systematic Review and Meta-Analysis of Taste Dysfunction in Chronic Rhinosinusitis. Laryngoscope. 2020 Jul 01;: Authors: Xie DX, Leland EM, Seal SM, Lin SY, Rowan NR Abstract OBJECTIVES: Patients with chronic rhinosinusitis (CRS) often describe alterations in sense of taste. These complaints have historically been attributed to olfactory dysfunction; however, there is evidence of direct, objective, gustatory disturbances...
Thu Jul 02, 2020 13:07
Related Articles Increased Pain Reporting by Head and Neck Cancer Patients at Radiation Oncology Consultation: A Quality-of-Life Analysis. Laryngoscope. 2020 Jul 01;: Authors: Havard M, Esslinger H, Mierzwa M, Kharofa J, Takiar V Abstract OBJECTIVES: Head and neck cancers (HNC) are associated with significant morbidity. Quality-of-life (QoL) analyses can assist with understanding subjective factors shaping the patient experience. Here,...
Thu Jul 02, 2020 13:07
Related Articles Efferent Synaptic Transmission at the Vestibular Type II Hair Cell Synapse. J Neurophysiol. 2020 Jul 01;: Authors: Yu Z, McIntosh JM, Sadeghi SG, Glowatzki E Abstract In the vestibular peripheral organs, type I and type II hair cells (HCs) transmit incoming signals via glutamatergic quantal transmission onto afferent nerve fibers. Additionally, type I HCs transmit via 'non-quantal' transmission to calyx afferent fibers,...
Thu Jul 02, 2020 13:07
Related Articles Sarcopenia and myosteatosis in patients undergoing curative radiotherapy for head and neck cancer: Impact on survival, treatment completion, hospital admission and cost. J Hum Nutr Diet. 2020 Jul 01;: Authors: Findlay M, Brown C, De Abreu Lourenço R, White K, Bauer J Abstract BACKGROUND: Computed tomography (CT) is the gold standard of body composition analysis at the tissue-organ level. The present study aimed to determine...
Thu Jul 02, 2020 13:07
Related Articles Prognostic importance of RUNX1 expression for head and neck adenoid cystic carcinoma. Oral Dis. 2020 Jul 01;: Authors: Soares CD, Bardález López de Cáceres CV, Rodrigues-Fernandes CI, Melo de Lima Morais T, de Almeida OP, de Carvalho MGF, Fonseca FP Abstract OBJECTIVE: In the present study, we aimed to investigate the prognostic value of RUNX1 expression in 76 patients with adenoid cystic carcinoma. MATERIALS...
Thu Jul 02, 2020 13:07
Related Articles Cost effectiveness of intraoperative pathology in the management of indeterminate thyroid nodules. Arch Endocrinol Metab. 2020 Jun 29;: Authors: Vuong CD, Watson WB, Kwon DI, Mohan SS, Perez MN, Lee SC, Simental AA Abstract OBJECTIVE: This study aims to determine the cost effectiveness of rapid frozen section (RFS) for indeterminate thyroid nodules. MATERIALS AND METHODS: A retrospective chart review was conducted...
Thu Jul 02, 2020 13:07
Related Articles Pure-tone audiometry without bone-conduction thresholds: using the digits-in-noise test to detect conductive hearing loss. Int J Audiol. 2020 Jul 01;:1-8 Authors: De Sousa KC, Smits C, Moore DR, Myburgh HC, Swanepoel W Abstract Objective: COVID-19 has been prohibitive to traditional audiological services. No- or low-touch audiological assessment outside a sound-booth precludes test batteries including bone conduction audiometry....
Thu Jul 02, 2020 13:07
Related Articles Clinical utility of apparent diffusion coefficient and diffusion-weighted magnetic resonance imaging for resectability assessment of head and neck tumors with skull base invasion. Head Neck. 2020 Jul 01;: Authors: Ogawa T, Kojima I, Wakamori S, Yoshida T, Murata T, Sakamoto M, Ohkoshi A, Nakanome A, Endo H, Endo T, Usubuchi H, Katori Y Abstract BACKGROUND: The usefulness of apparent diffusion coefficient (ADC) and diffusion-weighted...
Thu Jul 02, 2020 13:07
Related Articles Feasibility of Free Flap Reconstruction Following Salvage Robotic-Assisted Resection of Recurrent and Residual Oropharyngeal Cancer in 3 Patients. Ear Nose Throat J. 2020 Jul 01;:145561320937627 Authors: Williamson A, Haywood M, Awad Z Abstract INTRODUCTION: Human papilloma virus (HPV)-positive oropharyngeal cancer carries a good prognosis when managed with primary chemoradiotherapy. However, the dramatically increasing...
Thu Jul 02, 2020 13:07
Related Articles Occult Metastasis in Laryngeal Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis. Ann Otol Rhinol Laryngol. 2020 Jul 01;:3489420937744 Authors: Sharbel DD, Abkemeier M, Groves MW, Albergotti WG, Byrd JK, Reyes-Gelves C Abstract OBJECTIVE: The incidence of occult metastasis (OM) in laryngeal squamous cell carcinoma (SCC) is still widely debated. In this systematic review, we aim to determine the rate of OM in...
Thu Jul 02, 2020 13:07
Abstract Background This article aims to provide a description of conceptual dimensions and psychometric properties of the tools of oral and dental health literacy. Methods Two authors in this study conducted electronic searches in the Medline (via PubMed), and Embase databases to find relevant articles from 1990 to present day. Evaluation...
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Abstract Background It is unclear how many community-dwelling elderly (≥75 years) experience oral health problems (e.g. pain, dry mouth, chewing problems) and how they manage their dental care needs. This study aimed to assess self-reported oral health problems in elderly who are frail or have complex care needs, and their ability to organize dental care when reporting oral pain. ...
Thu Jul 02, 2020 03:00
Abstract Background Late diagnosis of a salivary fistula increases the risk of wound infection and scarring. The purpose of the present study was to identify a quantitative predictor of postoperative salivary fistula for cases treated with surgery. Methods Demographic, intraoperative and postoperative parameters for 57 cases that received...
Thu Jul 02, 2020 03:00
Related Articles Floseal: a novel application technique for the treatment of challenging epistaxis. Clin Otolaryngol. 2020 Jul 01;: Authors: Bonduelle Q, Biggs TC, Sipaul F Abstract There were 24,719 emergency admissions for epistaxis in English NHS trusts from April 2017-April 2018.1 Epistaxis is initially managed with external nasal pressure and ice, then cautery, nasal packing, surgery or embolisation, in ascending order. There is growing...
Thu Jul 02, 2020 13:07
Related Articles Validity of a dysphagia screening test following resection for head and neck cancer. Ir J Med Sci. 2020 Jun 30;: Authors: Horii N, Hasegawa Y, Sakuramoto-Sadakane A, Saito S, Nanto T, Nakao Y, Domen K, Ono T, Kishimoto H Abstract BACKGROUND: The aim of this study was to evaluate the validity of a dysphagia screening test (DST) in patients who have undergone resection for head and neck cancer (HNC). In addition, we examined...
Thu Jul 02, 2020 13:07
Related Articles Is there a role for chemotherapy and radiation in the treatment of patients with low-grade myofibroblastic sarcoma? Clin Transl Oncol. 2020 Jun 30;: Authors: Xu Y, Xu G, Wang X, Mao M, Wu H, Baklaushev VP, Chekhonin VP, Peltzer K, Wang G, Zhang C Abstract PURPOSE: Low-grade myofibroblastic sarcoma (LGMS) is a rare entity with a predilection for the head and neck. There are still no optimal treatment strategies for patients...
Thu Jul 02, 2020 13:07
Related Articles Collision tumor of squamous cell carcinoma and neuroendocrine carcinoma in the head and neck: A case report. World J Clin Cases. 2020 Jun 26;8(12):2610-2616 Authors: Wu SH, Zhang BZ, Han L Abstract BACKGROUND: There are many disputes about the definition, diagnosis, therapy, and prognosis of collision tumors. CASE SUMMARY: We describe a rare patient with a collision tumor consisting of neuroendocrine carcinoma...
Thu Jul 02, 2020 13:07
Related Articles Correction of malocclusion using sliding fibula osteotomy with sagittal split ramus osteotomy after mandible reconstruction. Maxillofac Plast Reconstr Surg. 2020 Dec;42(1):21 Authors: Lee DH, Kim SR, Jang S, Ahn KM, Lee JH Abstract Background: Fibula free flap mandible reconstruction is the standard procedure after wide resection of the mandible. Establishment and maintenance of normal occlusion are important in mandible...
Thu Jul 02, 2020 13:07
Related Articles Root causes of extended length of stay and unplanned readmissions after orthopedic surgery and hand surgery: a retrospective observational cohort study. Patient Saf Surg. 2020;14:27 Authors: Tolvi M, Tuominen-Salo H, Paavola M, Mattila K, Aaltonen LM, Lehtonen L Abstract Background: While previous studies have evaluated the effect of some patient characteristics (e.g. gender, American Society of Anesthesiologists (ASA)...
Thu Jul 02, 2020 13:07
Related Articles CCNY Accelerates Cylcin E Expression to Regulate the Proliferation of Laryngeal Carcinoma Cells via MEK/ERK Signaling Pathway. Cancer Manag Res. 2020;12:4889-4898 Authors: Zhao X, Jiang M, Wang Z, Chen X, Wang H, Yue W, Cai C Abstract Background: Laryngeal carcinoma is a common cancer among head and neck tumors, accounting for 0.5-1% new cancer cases or deaths of all tumors throughout the body. Despite improvements in diagnostic...
Thu Jul 02, 2020 13:07
Related Articles A Novel Tumor Suppressor SPINK5 Serves as an Independent Prognostic Predictor for Patients with Head and Neck Squamous Cell Carcinoma. Cancer Manag Res. 2020;12:4855-4869 Authors: Lv Z, Wu K, Qin X, Yuan J, Yan M, Zhang J, Wang L, Ji T, Cao W, Chen W Abstract Background: In our previous study, serine protease inhibitor Kazal-type 5 (SPINK5), which encodes the product of serine protease inhibitor lymphoepithelial Kazal-type-related...
Thu Jul 02, 2020 13:07
Related Articles MicroRNA-379-5p/YBX1 Axis Regulates Cellular EMT to Suppress Migration and Invasion of Nasopharyngeal Carcinoma Cells. Cancer Manag Res. 2020;12:4335-4346 Authors: Zhang F, Duan C, Yin S, Tian Y Abstract Background: Epithelial-mesenchymal transition (EMT) is a major actor modulating the metastasis of nasopharyngeal carcinoma (NPC). Increasing evidence indicates that microRNAs (miRs) are the important regulators of EMT program....
Thu Jul 02, 2020 13:07
Related Articles Effect of CXCR5-Positive Cell Infiltration on the Immune Contexture and Patient Prognosis in Head and Neck Squamous Cell Carcinoma. Onco Targets Ther. 2020;13:5869-5877 Authors: Chen J, Meng X, Zhou Q, Feng J, Zheng W, Wang Z, Wang J, Wang Y Abstract Purpose: CXCR5-positive (CXCR5+) tumor cell infiltration has different prognostic values in different types of cancer. The objective was to evaluate the effect of CXCR5+ cell...
Thu Jul 02, 2020 13:07
Related Articles Diagnostic Role of Dysregulated Circular RNA hsa_circ_0036722 in Laryngeal Squamous Cell Carcinoma. Onco Targets Ther. 2020;13:5709-5719 Authors: Guo Y, Huang Q, Zheng J, Hsueh CY, Yuan X, Heng Y, Zhou L Abstract Purpose: Dysregulated circular RNAs (circRNAs) have been shown to play important roles in various cancers, and could serve as diagnostic biomarkers. However, research focusing on the roles of the circRNAs in laryngeal...
Thu Jul 02, 2020 13:07
Related Articles Tension Pneumocephalus from Endoscopic Endonasal Surgery: A Case Series and Literature Review. Ther Clin Risk Manag. 2020;16:531-538 Authors: Li W, Liu Q, Lu H, Wang H, Zhang H, Hu L, Sun X, Gu Y, Li H, Zhao W, Wang D Abstract Purpose: Tension pneumocephalus (TP) caused by endoscopic endonasal surgery is a serious complication. We report four cases of TP caused by endoscopic surgery and review other cases in the literature,...
Thu Jul 02, 2020 13:07
Related Articles Effects of Zinc Oxide Nanoparticles in HUVEC: Cyto- and Genotoxicity and Functional Impairment After Long-Term and Repetitive Exposure in vitro. Int J Nanomedicine. 2020;15:4441-4452 Authors: Poier N, Hochstöger J, Hackenberg S, Scherzad A, Bregenzer M, Schopper D, Kleinsasser N Abstract Purpose: The present study focuses on threshold levels for cytotoxicity after long-term and repetitive exposure for HUVEC as a model for...
Thu Jul 02, 2020 13:07
Related Articles Essential review points on the retrospective study of osteoradionecrosis in the jaws. J Korean Assoc Oral Maxillofac Surg. 2020 Jun 30;46(3):208-210 Authors: Seo MH, Kim SM Abstract Recently, after reviewing the online journal, Journal of the Korean Association of Oral and Maxillofacial Surgeons , we found a recently published original article by Manzano et al., entitled, "Retrospective study of osteoradionecrosis in the...
Thu Jul 02, 2020 13:07
Related Articles Efficacy of arthrocentesis and lavage for treatment of post-traumatic arthritis in temporomandibular joints. J Korean Assoc Oral Maxillofac Surg. 2020 Jun 30;46(3):174-182 Authors: Park JY, Lee JH Abstract Objectives: Joint injuries frequently lead to progressive joint degeneration that causes articular disc derangement, joint inflammation, and osteoarthritis. Such arthropathies that arise after trauma are defined as post-traumatic...
Thu Jul 02, 2020 13:07
Related Articles Variation in tonsillectomy cost and revisit rates: analysis of administrative and billing data from US children's hospitals. BMJ Qual Saf. 2020 Jun 30;: Authors: Mahant S, Richardson T, Keren R, Srivastava R, Meier J, Pediatric Research in Inpatient Setting (PRIS) Network Abstract BACKGROUND: Tonsillectomy is one of the most common and cumulatively expensive surgical procedures in children. We determined if substantial...
Thu Jul 02, 2020 13:07
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