Publication date: Available online 2 July 2020Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): S. Jain, V. Sharma, S.K. Patro, P. Khera, T. Yadav, D. Kaushal, A. Goyal
Thu Jul 02, 2020 13:47
Publication date: Available online 2 July 2020Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Adrian L. James, Pranesh Chakraborty, Christopher Tomlinson, Robert V. Harrison
Thu Jul 02, 2020 13:47
Related Articles Occult Metastasis in Laryngeal Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis. Ann Otol Rhinol Laryngol. 2020 Jul 01;:3489420937744 Authors: Sharbel DD, Abkemeier M, Groves MW, Albergotti WG, Byrd JK, Reyes-Gelves C Abstract OBJECTIVE: The incidence of occult metastasis (OM) in laryngeal squamous cell carcinoma (SCC) is still widely debated. In this systematic review, we aim to determine the rate of OM in...
Thu Jul 02, 2020 13:45
Related Articles In Vitro Assessment of Homeopathic Potencies of Hydrastis canadensis on Hormone-Dependent and Independent Breast Cancer. Homeopathy. 2020 Jul 01;: Authors: Khan S, Nayak D, Khurana A, Manchanda RK, Tandon C, Tandon S Abstract BACKGROUND: Breast cancer is the second leading cause of cancer-related deaths in women. Conventional treatment such as chemotherapy, hormonal therapy and radiotherapy has decreased the mortality...
Thu Jul 02, 2020 13:41
Related Articles Synergistic Antitumor Effects of Combined Treatment with HSP90 Inhibitor and PI3K/mTOR Dual Inhibitor in Cisplatin-Resistant Human Bladder Cancer Cells. Yonsei Med J. 2020 Jul;61(7):587-596 Authors: Kim HJ, Gong MK, Yoon CY, Kang J, Yun M, Cho NH, Rha SY, Choi YD Abstract PURPOSE: The current study aimed to investigate the synergistic antitumor effect of combined treatment with 17-DMAG (HSP90 inhibitor) and NVP-BEZ235 (PI3K/mTOR...
Thu Jul 02, 2020 13:41
Related Articles Single-cell sequencing reveals novel mechanisms of Aflatoxin B1-induced hepatotoxicity in S phase-arrested L02 cells. Cell Biol Toxicol. 2020 Jul 01;: Authors: Zhang B, Dai Y, Zhu L, He X, Huang K, Xu W Abstract Aflatoxin B1 (AFB1) is widely distributed in nature and is confirmed to be the most toxic of all the aflatoxins, whose predominant metabolism site is the liver. As a well-studied and vital mode of epigenetic modifications,...
Thu Jul 02, 2020 13:41
Related Articles Anlotinib Suppresses Colorectal Cancer Proliferation and Angiogenesis via Inhibition of AKT/ERK Signaling Cascade. Cancer Manag Res. 2020;12:4937-4948 Authors: Yang Q, Ni L, Imani S, Xiang Z, Hai R, Ding R, Fu S, Wu JB, Wen Q Abstract Background: Anlotinib is a highly potent multi-target tyrosine kinase inhibitor, with very good anti-tumor activity against a variety of solid tumors. However, its effect on colorectal cancer...
Thu Jul 02, 2020 13:41
Related Articles A Novel Tumor Suppressor SPINK5 Serves as an Independent Prognostic Predictor for Patients with Head and Neck Squamous Cell Carcinoma. Cancer Manag Res. 2020;12:4855-4869 Authors: Lv Z, Wu K, Qin X, Yuan J, Yan M, Zhang J, Wang L, Ji T, Cao W, Chen W Abstract Background: In our previous study, serine protease inhibitor Kazal-type 5 (SPINK5), which encodes the product of serine protease inhibitor lymphoepithelial Kazal-type-related...
Thu Jul 02, 2020 13:41
Related Articles Synergistic Anticancer Effects of Gemcitabine with Pitavastatin on Pancreatic Cancer Cell Line MIA PaCa-2 in vitro and in vivo. Cancer Manag Res. 2020;12:4645-4665 Authors: Chen YH, Chen YC, Lin CC, Hsieh YP, Hsu CS, Hsieh MC Abstract Background: Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy with an overall 5-year survival rate of 9.3%, and this malignancy is expected to become the second leading...
Thu Jul 02, 2020 13:41
Related Articles ELL2 Is Required for the Growth and Survival of AR-Negative Prostate Cancer Cells. Cancer Manag Res. 2020;12:4411-4427 Authors: Wang Z, Pascal LE, Chandran UR, Chaparala S, Lv S, Ding H, Qi L, Wang Z Abstract Background: Elongation factor for RNA polymerase II 2 (ELL2) was reported as a putative tumor suppressor in the prostate. ELL2 is frequently down-regulated in prostatic adenocarcinoma specimens, and loss of ELL2 induced...
Thu Jul 02, 2020 13:41
Related Articles HOPX Is an Epigenetically Inactivated Tumor Suppressor and Overexpression of HOPX Induce Apoptosis and Cell Cycle Arrest in Breast Cancer. Onco Targets Ther. 2020;13:5955-5965 Authors: You Q, Geng Y, Ye H, Zhu G, Gao X, Zhu H Abstract Background: Evidence has been shown that abnormal DNA methylation plays a vital role in the progression of breast cancer via silencing of gene expression. The results of bisulfite sequencing...
Thu Jul 02, 2020 13:41
Related Articles PSAT1 Regulated Oxidation-Reduction Balance Affects the Growth and Prognosis of Epithelial Ovarian Cancer. Onco Targets Ther. 2020;13:5443-5453 Authors: Zhang Y, Li J, Dong X, Meng D, Zhi X, Yuan L, Yao L Abstract Introduction: A growing number of studies have found that the serine-glycine biosynthesis pathway is highly activated for biosynthesis in cancer progression and metastasis. Phosphoserine aminotransferase 1 (PSAT1)...
Thu Jul 02, 2020 13:41
Related Articles Brevilin A, a Natural Sesquiterpene Lactone Inhibited the Growth of Triple-Negative Breast Cancer Cells via Akt/mTOR and STAT3 Signaling Pathways. Onco Targets Ther. 2020;13:5363-5373 Authors: Qu Z, Lin Y, Mok DK, Bian Q, Tai WC, Chen S Abstract Purpose: Triple-negative breast cancer (TNBC) is a a breast cancer subtype characterized by a lack of estrogen receptor, progesterone receptor and human epidermal growth receptor...
Thu Jul 02, 2020 13:41
Related Articles Diosgenin and GSK126 Produce Synergistic Effects on Epithelial-Mesenchymal Transition in Gastric Cancer Cells by Mediating EZH2 via the Rho/ROCK Signaling Pathway. Onco Targets Ther. 2020;13:5057-5067 Authors: Liu S, Rong G, Li X, Geng L, Zeng Z, Jiang D, Yang J, Wei Y Abstract Background: Diosgenin, a natural steroidal saponin isolated from Trigonella foenum-graecum, has been reported to exert anti-cancer effects. Inhibitors...
Thu Jul 02, 2020 13:41
Related Articles Aprepitant Sensitizes Acute Myeloid Leukemia Cells to the Cytotoxic Effects of Cytosine Arabinoside in vitro and in vivo. Drug Des Devel Ther. 2020;14:2413-2422 Authors: Wu H, Cheng X, Huang F, Shao G, Meng Y, Wang L, Wang T, Jia X, Yang T, Wang X, Fu C Abstract Purpose: Acute myeloid leukemia (AML) is a complex malignancy characterized by the clonal expansion of immature myeloid precursors. The standard treatment for newly...
Thu Jul 02, 2020 13:41
Related Articles A novel 4-aminoquinazoline derivative, DHW-208, suppresses the growth of human breast cancer cells by targeting the PI3K/AKT/mTOR pathway. Cell Death Dis. 2020 Jun 30;11(6):491 Authors: Wang S, Zhang Y, Ren T, Wu Q, Lu H, Qin X, Liu Y, Ding H, Zhao Q Abstract Breast cancer is one of the most frequent cancers among women worldwide. However, there is still no effective therapeutic strategy for advanced breast cancer that...
Thu Jul 02, 2020 13:41
Related Articles Repurposing the FDA-Approved Antiviral Drug Ribavirin as Targeted Therapy for Nasopharyngeal Carcinoma. Mol Cancer Ther. 2020 Jun 30;: Authors: Huq S, Casaos J, Serra R, Peters M, Xia Y, Ding AS, Ehresman J, Kedda JN, Morales M, Gorelick NL, Zhao T, Ishida W, Perdomo-Pantoja A, Cecia A, Ji C, Suk I, Sidransky D, Brait M, Brem H, Skuli N, Tyler B Abstract Nasopharyngeal carcinoma (NPC) is a squamous cell carcinoma with a...
Thu Jul 02, 2020 13:41
Related Articles Bioinformatic Analyses of miRNA-mRNA Signature during hiPSC Differentiation towards Insulin-Producing Cells upon HNF4α Mutation. Biomedicines. 2020 Jun 27;8(7): Authors: Ghila L, Bjørlykke Y, Legøy TA, Vethe H, Furuyama K, Chera S, Ræder H Abstract Mutations in the hepatocyte nuclear factor 4α (HNF4α) gene affect prenatal and postnatal pancreas development, being characterized by insulin-producing β-cell dysfunction. Little...
Thu Jul 02, 2020 13:41
Related Articles Dietary Crocin is Protective in Pancreatic Cancer while Reducing Radiation-Induced Hepatic Oxidative Damage. Nutrients. 2020 Jun 26;12(6): Authors: Bakshi HA, Zoubi MSA, Faruck HL, Aljabali AAA, Rabi FA, Hafiz AA, Al-Batanyeh KM, Al-Trad B, Ansari P, Nasef MM, Charbe NB, Satija S, Mehta M, Mishra V, Gupta G, Abobaker S, Negi P, Azzouz IM, Dardouri AAK, Dureja H, Prasher P, Chellappan DK, Dua K, Silva MWD, Tanani ME, McCarron PA, M Tambuwala...
Thu Jul 02, 2020 13:41
Related Articles Frontline Science: A flexible kink in the transmembrane domain impairs β2 integrin extension and cell arrest from rolling. J Leukoc Biol. 2020 02;107(2):175-183 Authors: Sun H, Fan Z, Gingras AR, Lopez-Ramirez MA, Ginsberg MH, Ley K Abstract β2 integrins are the main adhesion molecules in neutrophils and other leukocytes and are rapidly activated by inside-out signaling, which results in conformational changes that are transmitted...
Thu Jul 02, 2020 13:41
Related Articles Ginsenoside Rg5 induces G2/M phase arrest, apoptosis and autophagy via regulating ROS-mediated MAPK pathways against human gastric cancer. Biochem Pharmacol. 2019 10;168:285-304 Authors: Liu Y, Fan D Abstract Ginsenoside Rg5, a rare saponin belonging to the family of protopanaxadiol ginsenosides, has been demonstrated to have potential anti-tumor effects in various cancers. However, the effect of Rg5 on human gastric cancer...
Thu Jul 02, 2020 13:41
Related Articles Senescence suppressed proliferation of host hepatocytes is precondition for liver repopulation. Biochem Biophys Res Commun. 2019 08 20;516(2):591-598 Authors: Chen J, Yang T, Song S, Liu Q, Sun Y, Zhao L, Fu Z, Wang MJ, Hu YP, Chen F Abstract In the fumarylacetoacetate hydrolase deficient (Fah-/-) mouse, massive liver repopulation can be easily obtained after transplanted hepatocytes. Understanding the mechanisms of complete...
Thu Jul 02, 2020 13:41
Publication date: Available online 1 July 2020Source: Photodiagnosis and Photodynamic TherapyAuthor(s): Abdullah Al Nazeh, Abdul Aziz Alshahrani, Salem Almoammar, Muhammad Abdullah Kamran, Rafi A Togoo, Ibrahim Alshahrani
Thu Jul 02, 2020 13:40
Publication date: Available online 2 July 2020Source: American Journal of Infection ControlAuthor(s): Kathleen M. McMullen, Barbara A. Smith, Terri Rebman
Thu Jul 02, 2020 13:40
Publication date: Available online 2 July 2020Source: American Journal of Infection ControlAuthor(s): Claudia Crimi, Pietro Impellizzeri, Raffaele Campisi, Lucia Spicuzza, Carlo Vancheri, Nunzio Crimi
Thu Jul 02, 2020 13:40
Publication date: Available online 1 July 2020Source: American Journal of Infection ControlAuthor(s): Stephanie Chen, Megan O'Malley, Vineet Chopra
Thu Jul 02, 2020 13:40
Publication date: Available online 1 July 2020Source: American Journal of Infection ControlAuthor(s): Muhammad Hasnain, Muhammad Fermi Pasha, Imran Ghani, Rahmat Budiarto
Thu Jul 02, 2020 13:40
Nature Communications, Published online: 02 July 2020; doi:10.1038/s41467-020-17295-1Author Correction: A strong and ductile medium-entropy alloy resists hydrogen embrittlement and corrosion
Thu Jul 02, 2020 03:00
Thu Jul 02, 2020 03:00
Related Articles Gastric Schwannoma In a Patient Undergoing Sleeve Gastrectomy: Uncommon Gastric Tumor Discovered Incidentally During a Common Gastric Procedure. Am J Case Rep. 2020 Jul 01;21:e924432 Authors: Al Dandan O, Hassan A, Anastasiou J, Al-Turaifi Z, Alabbad A, Refai O, Alshomimi S Abstract BACKGROUND Obesity is a major global health issue associated with significant co-morbidities. Regarding its treatment, the use of bariatric procedures...
Thu Jul 02, 2020 13:37
Related Articles Acute Myopericarditis with Pericardial Effusion and Cardiac Tamponade in a Patient with COVID-19. Am J Case Rep. 2020 Jul 01;21:e925554 Authors: Purohit R, Kanwal A, Pandit A, Patel BM, Meininger GR, Brown JJ, Kaliyadan AG, Saini A Abstract BACKGROUND Coronavirus disease 2019 (COVID-19) is primarily a respiratory illness. However, with rising numbers of cases, multiple reports of cardiovascular manifestations have emerged. We...
Thu Jul 02, 2020 13:37
New England Journal of Medicine, Ahead of Print.
Wed Jul 01, 2020 12:00
New England Journal of Medicine, Ahead of Print.
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New England Journal of Medicine, Ahead of Print.
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New England Journal of Medicine, Volume 383, Issue 1, Page 24-34, July 2020.
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