Related Articles A Cross-Sectional Comparison of the Prevalence of Obstructive Sleep Apnea Symptoms in Adults With Down Syndrome in Scotland and Japan. Am J Intellect Dev Disabil. 2020 Jul 01;125(4):260-273 Authors: Hill EA, Sawatari H, Nishizaka MK, Fairley DM, Chishaki A, Funakoshi K, Riha RL, Ando SI Abstract Small studies in Western populations report a high prevalence of obstructive sleep apnea (OSA) in adults with Down syndrome. To date,...
Thu Jul 02, 2020 13:19
Related Articles Does Nasal Obstruction Induce Obstructive Sleep Apnea in Healthy Women? Nat Sci Sleep. 2020;12:347-355 Authors: Pittaway I, Ishkova A, Bean H, McCarthy S, Lay I, Avraam J, Dawson A, Thornton T, Nicholas CL, Trinder J, O'Donoghue FJ, Jackson ML, Jordan AS Abstract Purpose: Obstructive sleep apnea (OSA) is less prevalent among women and is associated with different symptoms and consequences to OSA in men. The reasons for these...
Thu Jul 02, 2020 13:19
Related Articles Normative Data for Cortical Evoked Response Audiometry of a Heterogeneous Indian Population and Its Comparison with Behavioral Audiometry. Ann Indian Acad Neurol. 2020 May-Jun;23(3):296-302 Authors: Misale P, Lepcha A, Thomas P, Sebastian S, Sebastian T Abstract Objective: The objective of the study is to establish normative values of cortical evoked response audiometry (CERA) in a heterogeneous Indian population and correlate...
Thu Jul 02, 2020 13:19
Related Articles Evidence for Linear but Not Helical Automatic Representation of Pitch in the Human Auditory System. J Cogn Neurosci. 2019 05;31(5):669-685 Authors: Regev TI, Nelken I, Deouell LY Abstract The perceptual organization of pitch is frequently described as helical, with a monotonic dimension of pitch height and a circular dimension of pitch chroma, accounting for the repeating structure of the octave. Although the neural representation...
Thu Jul 02, 2020 13:19
Related Articles Behavioral and electrophysiological investigation of speech perception deficits in silence, noise and envelope conditions in developmental dyslexia. Neuropsychologia. 2019 07;130:3-12 Authors: Frey A, François C, Chobert J, Besson M, Ziegler JC Abstract The present study investigated whether children with developmental dyslexia showed specific deficits in the perception of three phonetic features (voicing, place, and manner...
Thu Jul 02, 2020 13:19
Abstract Next-generation approaches for protein sequencing are now emerging that could have the potential to revolutionize the field in proteomics. One such sequencing method involves fluorescence-based imaging of immobilized peptides in which the N-terminal amino acid of a polypeptide is readout sequentially by a series of fluorescently labeled biomolecules. When selectively bound to a specific N-terminal amino acid, the NAAB (N-terminal amino acid binder) affinity reagent identifies...
Thu Jul 02, 2020 03:00
Abstract Taxol, a phyto-extracted diterpenoid, is the most commercially needed drug in cancer chemotherapy. In spite of the microbial production of taxol being successful and prospective, the reported yields are still not sufficient for large-scale production. Thus, the discovery of new taxol-producing microbial strains and production enhancement methodologies such as process optimization, strain improvement, and immobilization technique are the main objectives....
Thu Jul 02, 2020 03:00
Related Articles Pleomorphic rhabdomyosarcoma of the spermatic cord and a secondary hydrocele testis: A case report. World J Clin Cases. 2020 Jun 26;8(12):2641-2646 Authors: Chen X, Zou C, Yang C, Gao L, Bi LK, Xie DD, Yu DX Abstract BACKGROUND: Pleomorphic rhabdomyosarcoma (RMS) of the spermatic cord is a group of rare neoplasms, and a secondary hydrocele testis occasionally occurs. The misdiagnosis of paratesticular mass may lead to a therapeutic...
Thu Jul 02, 2020 13:18
Related Articles Goblet Cell Adenocarcinoma With Heterotopic Ossification: A Rare Case Report and Review of Literature. Cureus. 2020 May 27;12(5):e8312 Authors: Alghamdi M, Mathew T, Breaux A, Chopra H Abstract Heterotopic bone formation is a rare phenomenon when associated with gastrointestinal neoplasms. Here we present a rare case of heterotopic ossification associated with goblet cell adenocarcinoma of the appendix, and a literature review...
Thu Jul 02, 2020 13:18
Related Articles Cutaneous Myoepithelioma: An Unusual Tumor in the Hand. Case Rep Pathol. 2020;2020:3747013 Authors: Montalvo N, Redrobán L, Galarza D, Ramírez I Abstract Cutaneous myoepithelioma (CM) is a rare tumor among the primary skin neoplasms. We present the case of a patient with a diagnosis of CM in the right hypothenar region. Histological study showed a proliferation of myoepithelial cells with a solid, reticular growth pattern in...
Thu Jul 02, 2020 13:18
Related Articles Candidate protein biomarkers in pancreatic neuroendocrine neoplasms grade 3. Sci Rep. 2020 Jun 30;10(1):10639 Authors: Ali AS, Perren A, Lindskog C, Welin S, Sorbye H, Grönberg M, Janson ET Abstract Pancreatic neuroendocrine neoplasms (PanNENs) are rare tumours that compose 1-2% of all pancreatic tumours. Patients with metastatic grade 3 neoplasia are usually treated with chemotherapy but have a poor progression-free and overall...
Thu Jul 02, 2020 13:18
Related Articles Addition of anti-estrogen treatment in patients with malignant PEComa progressing to mTOR inhibitors. Clin Cancer Res. 2020 Jun 30;: Authors: Sanfilippo R, Fabbroni C, Fucà G, Fumagalli E, Morosi C, Sbaraglia M, Gronchi A, Collini P, Dei Tos AP, Casali PG Abstract PURPOSE: Perivascular epitheloid cell tumors (PEComas) are rare mesenchymal neoplasms. mTOR inhibitors are the most active agents in PEComa and in patients progressing...
Thu Jul 02, 2020 13:18
Related Articles Middle ear adenomatous neuroendocrine tumors: suggestion for surgical strategy. Braz J Otorhinolaryngol. 2020 Jun 15;: Authors: Xie B, Zhang S, Dai C, Liu Y Abstract INTRODUCTION: Middle ear adenomatous neuroendocrine tumors are extremely rare neoplasms with epithelial and neuroendocrine differentiation, accounting for fewer than 2% of all middle and inner ear tumors. Universal standard surgical procedures for different stages...
Thu Jul 02, 2020 13:18
Related Articles Anaplastic thyroid carcinoma: a nationwide cohort study on incidence, treatment and survival in the Netherlands over 3 decades. Eur J Endocrinol. 2020 Aug;183(2):203-209 Authors: de Ridder M, Nieveen van Dijkum E, Engelsman A, Kapiteijn E, Klümpen HJ, Rasch CRN Abstract Objective: To perform a nationwide population based study in ATC on incidence, treatment and survival. Design: Retrospective cohort study. ...
Thu Jul 02, 2020 13:18
Related Articles Pericardial Effusion in a Young Man: A Rare Presentation of Thymoma. Isr Med Assoc J. 2020 May;22(5):328-329 Authors: Moady G, Daud E, Galilee R, Sabo E, Mazareb S, Atar S PMID: 32378828 [PubMed - indexed for MEDLINE]
Thu Jul 02, 2020 13:18
Related Articles First Targeted Therapy for Rare Form of GI Stromal Tumors. Am J Nurs. 2020 05;120(5):23 Authors: Aschenbrenner DS PMID: 32332360 [PubMed - indexed for MEDLINE]
Thu Jul 02, 2020 13:18
Related Articles First Treatment for Rare Soft Tissue Cancer. Am J Nurs. 2020 05;120(5):22 Authors: Aschenbrenner DS PMID: 32332358 [PubMed - indexed for MEDLINE]
Thu Jul 02, 2020 13:18
Related Articles Hepatobiliary Adverse Events. Adv Exp Med Biol. 2020;1244:271-276 Authors: Abu-Sbeih H, Wang Y Abstract Immune checkpoint inhibitors (ICIs) are increasingly used for multiple cancer types. Hepatotoxicity is a reported adverse event of ICI treatment. It can present as asymptomatic elevation of aspartate transaminase and alanine transaminase or symptomatic hepatitis with fever, malaise, and even death in rare cases. The diagnosis...
Thu Jul 02, 2020 13:18
Related Articles Complete Molar Pregnancy in Posmenopausal Woman-a Case Report. Med Arch. 2019 Dec;73(6):436-437 Authors: Fatusic J, Hudic I Abstract Introduction: Gestational trophoblastic desease (GTD) is disease typical for reproductive period of women and is extremly rare in postmenopausal period of woman's life. Aim: To present a rare case of mollar pregnancy in 57 years of age postmenopausal woman. Case report: A multiparous...
Thu Jul 02, 2020 13:18
Related Articles New Discorhabdin B Dimers with Anticancer Activity from the Antarctic Deep-Sea Sponge Latrunculia biformis. Mar Drugs. 2020 Feb 11;18(2): Authors: Li F, Janussen D, Tasdemir D Abstract Latrunculia sponges represent a rich source of discorhabdin-type pyrroloiminoquinone alkaloids, a few of which comprise a dimeric structure. The anticancer-activity-guided isolation of the n-hexane subextract of the Antarctic deep-sea sponge...
Thu Jul 02, 2020 13:18
Related Articles [Ureteric and testicular mestastasis 25 years after nephrectomy : Long-term survival with metastatic renal cell carcinoma]. Urologe A. 2020 Jun;59(6):710-712 Authors: de Jonge L, Pahernik S, Pandey A Abstract A 70-year-old man with multiple metastasized renal cell carcinoma (RCC) presented himself in our clinic 25 years after initial diagnosis with newly developed hematuria and conspicuous right testis. The biopsy of the left...
Thu Jul 02, 2020 13:18
Related Articles Management of a feline gastric stromal cell tumour with toceranib phosphate: a case study. Aust Vet J. 2020 May;98(5):181-184 Authors: McGregor O, Moore AS, Yeomans S Abstract BACKGROUND: A fifteen-year old, female spayed domestic longhaired cat was presented for a routine vaccination during which an incidental abdominal mass was palpated. After further inquiry, occasional vomiting was reported to occur once every few weeks...
Thu Jul 02, 2020 13:18
Related Articles Plexiform Fibromyxoma: A Rare Mesenchymal Tumor Found in the Esophagus. Am J Gastroenterol. 2020 05;115(5):648 Authors: Tang J, Liu F PMID: 31809299 [PubMed - indexed for MEDLINE]
Thu Jul 02, 2020 13:18
Related Articles Two iPSC lines generated from the bone marrow of a relapsed/refractory AML patient display normal karyotypes and myeloid differentiation potential. Stem Cell Res. 2019 12;41:101587 Authors: Yamasaki AE, King NE, Matsui H, Jepsen K, Panopoulos AD Abstract Using iPSCs to study cancer has been complicated by the fact that many cancer cells are difficult to reprogram, which has been attributed to the genomic abnormalities present....
Thu Jul 02, 2020 13:18
Related Articles GENYOi005-A: An induced pluripotent stem cells (iPSCs) line generated from a patient with Familial Platelet Disorder with associated Myeloid Malignancy (FPDMM) carrying a p.Thr196Ala variant. Stem Cell Res. 2019 12;41:101603 Authors: Lamolda M, Montes R, Simón I, Perales S, Martínez-Navajas G, Lopez-Onieva L, Ríos-Pelegrina R, Del Moral RG, Griñan-Lison C, Marchal JA, Lozano ML, Ramos-Mejia V, Rivera J, Bastida JM, Real PJ Abstract...
Thu Jul 02, 2020 13:18
Related Articles Generation of four induced pluripotent stem cell lines, GZWWTi001-A, GZWTZi001-A, GZWXYi001-A, and GZWXDi001-A, derived from peripheral blood mononuclear cells from a family with asparagine synthetase deficiency. Stem Cell Res. 2019 12;41:101583 Authors: Yingjun X, Dian L, Ding W, Shaoying L, Yinghong Y, Nengqing L, Xiaofang S Abstract Asparagine synthetase (ASNS) deficiency (ASNSD; MIM #615574) is a rare neurodevelopmental...
Thu Jul 02, 2020 13:18
Related Articles Blinatumomab compared with standard of care for the treatment of adult patients with relapsed/refractory Philadelphia chromosome-positive B-precursor acute lymphoblastic leukemia. Cancer. 2020 01 15;126(2):304-310 Authors: Rambaldi A, Ribera JM, Kantarjian HM, Dombret H, Ottmann OG, Stein AS, Tuglus CA, Zhao X, Kim C, Martinelli G Abstract BACKGROUND: A single-arm, phase 2 trial demonstrated the efficacy and safety of blinatumomab,...
Thu Jul 02, 2020 13:18
Related Articles Surgical Management of Thoracic Multiple Exostoses. Ann Thorac Surg. 2020 05;109(5):e361-e362 Authors: Kanthasamy S, Aresu G, Peryt A, Coonar AS Abstract Hereditary multiple exostoses is a rare autosomal dominant condition resulting in the development of multiple osteochondromas. We present the case of a 25-year-old woman with hereditary multiple exostoses who was referred for thoracic surgery assessment due to severe right-sided...
Thu Jul 02, 2020 13:18
Related Articles Intrathoracic Myxoid Spindle Cell Lipoma: A Rare Presentation of a Myxoid Neoplasm. Ann Thorac Surg. 2020 05;109(5):e343-e345 Authors: Schulberg SP, Lim D, Hoda ST, Vaynblat M Abstract Here we present the case of a 38-year-old man with an incidentally found right upper lobe lung mass. The patient underwent thoracoscopic resection of the mass, which revealed a myxoid spindle cell lipoma. That is an exceedingly rare location...
Thu Jul 02, 2020 13:18
Related Articles Thymic Small Cell Carcinoma Associated With Lambert-Eaton Myasthenic Syndrome. Ann Thorac Surg. 2020 05;109(5):e347-e348 Authors: Hashimoto S, Hayasaka K, Suzuki K, Endoh M, Yanagawa N, Shiono S Abstract Thymic small cell cancer is a very rare type of thymic epithelial tumor. Lambert-Eaton myasthenic syndrome is a rare paraneoplastic syndrome associated with thymic epithelial tumors. We report an extremely rare case of Lambert-Eaton...
Thu Jul 02, 2020 13:18
Related Articles Aorticopulmonary Paraganglioma With Symptomatic Postoperative Bradycardia. Ann Thorac Surg. 2020 05;109(5):e367-e369 Authors: Chang SH, Yapar I, Kozower BD Abstract Aorticopulmonary paragangliomas are rare middle mediastinal masses that are often treated with surgery. In addition to the technical challenge of resection due to location near critical structures, these paragangliomas can have postoperative complications due to...
Thu Jul 02, 2020 13:18
Related Articles Combined Ectopic Variation of the Right Upper Pulmonary Vein and Bronchus. Ann Thorac Surg. 2020 05;109(5):e353-e355 Authors: Huang L, Wu P, Li W, Chai Y Abstract Ectopia of the right upper pulmonary vein (RUV) is rare and sometimes combined with tracheal bronchus. Such anomalies can affect surgical procedures. We report the case of a 66-year-old woman with lung cancer in which preoperative three-dimensional computed tomography...
Thu Jul 02, 2020 13:18
Related Articles Malignant Mesothelioma of the Vaginal Tunic and Peritoneum in a Young Stallion. J Equine Vet Sci. 2019 09;80:76-79 Authors: MacMillan KM, Martinson SA, Smith M, Lofstedt J Abstract Mesothelioma is a rare malignancy in horses. This report describes a case in which marked hemoperitoneum, moderate anemia, and moderate dependent edema were the presenting clinical signs in a 2-year-old Standardbred stallion with mesothelioma of the...
Thu Jul 02, 2020 13:18
Related Articles Standing Hand-Assisted Laparoscopic Diagnosis and Treatment of a Rare Case of Uterine Adenocarcinoma in an 18-Year-Old Mare. J Equine Vet Sci. 2019 08;79:39-44 Authors: Quéré E, Bourzac C, Farfan M, Losada A, Volmer C, Mespoulhès-Rivière C Abstract An 18-year-old French Trotter mare was presented to the Clinique Equine, Ecole Nationale Vétérinaire d'Alfort, for exploration of a 3-month-duration vaginal bleeding. A transrectal...
Thu Jul 02, 2020 13:18
Related Articles Gallbladder leiomyoma treated by laparoscopic cholecystectomy in a dog. J Am Vet Med Assoc. 2019 07 01;255(1):85-89 Authors: Lovell S, Singh A, Zur Linden A, Hagen C, Cuq B Abstract CASE DESCRIPTION: A 12-year-old spayed female Chinese Crested was referred because of a mass detected in the gallbladder during ultrasonographic evaluation of the abdomen, which had been prompted by a history of high serum liver enzyme activities....
Thu Jul 02, 2020 13:18
Related Articles Trimodal Therapy for Bladder Cancer: You Get What You Don't Pay For. JAMA Surg. 2019 08 01;154(8):e191637 Authors: Cole AP, Trinh QD PMID: 31166585 [PubMed - indexed for MEDLINE]
Thu Jul 02, 2020 13:18
Related Articles Antemortem diagnosis of esophageal squamous cell carcinoma in a blue-fronted Amazon parrot (Amazona aestiva) and a mealy Amazon parrot (Amazona farinosa). J Am Vet Med Assoc. 2019 Jun 01;254(11):1324-1328 Authors: Staudenmaier AM, Simone-Freilicher EA, Noonan BP, Ewing PJ Abstract CASE DESCRIPTION: A 28-year-old blue-fronted Amazon parrot (Amazona aestiva) with a 1 -week history of regurgitation-like movement of the neck and...
Thu Jul 02, 2020 13:18
Related Articles Treatments and outcomes of spinal metastasis from thymic epithelial tumors: 10-year experience with 15 patients in a single center. Eur Spine J. 2019 06;28(6):1520-1528 Authors: Jia Q, Yang J, Hu J, Liu T, Yang C, Wei H, Yang X, Xiao J Abstract PURPOSE: Although thymic epithelial tumors (TETs) are rare, their spinal metastases are even rarer, and they have only been described in a few case reports. The aim of the present study...
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