Related Articles Burned Ear Reconstruction Using a Superficial Temporal Fascia Flap. Ear Nose Throat J. 2020 Jul 01;:145561320937620 Authors: Guo P, Jiang H, Yang Q, He L, Lin L, Pan B Abstract OBJECTIVES: Ear deformity caused by burns is one of the most difficult types of deformity to treat with plastic surgery, and the reconstruction of burned ears undoubtedly remains a substantial challenge. This study aims to report the therapeutic...
Thu Jul 02, 2020 16:45
Related Articles Feasibility of Free Flap Reconstruction Following Salvage Robotic-Assisted Resection of Recurrent and Residual Oropharyngeal Cancer in 3 Patients. Ear Nose Throat J. 2020 Jul 01;:145561320937627 Authors: Williamson A, Haywood M, Awad Z Abstract INTRODUCTION: Human papilloma virus (HPV)-positive oropharyngeal cancer carries a good prognosis when managed with primary chemoradiotherapy. However, the dramatically increasing...
Thu Jul 02, 2020 16:45
Related Articles Development of a Novel Prognostic Model to Predict 6-Month Swallowing Recovery After Ischemic Stroke. Stroke. 2020 02;51(2):440-448 Authors: Lee WH, Lim MH, Seo HG, Seong MY, Oh BM, Kim S Abstract Background and Purpose- The aim of this study was to explore clinical and radiological prognostic factors for long-term swallowing recovery in patients with poststroke dysphagia and to develop and validate a prognostic model using...
Thu Jul 02, 2020 16:41
Related Articles Associations between multimorbidity and adverse clinical outcomes in patients with chronic kidney disease: a systematic review and meta-analysis. BMJ Open. 2020 Jun 30;10(6):e038401 Authors: Sullivan MK, Rankin AJ, Jani BD, Mair FS, Mark PB Abstract OBJECTIVE: To systematically review the literature exploring the associations between multimorbidity (the presence of two or more long-term conditions (LTCs)) and adverse clinical...
Thu Jul 02, 2020 16:37
Related Articles Global PRoMiSe (Perioperative Recommendations for Medication Safety): protocol for a mixed-methods study. BMJ Open. 2020 Jun 30;10(6):e038313 Authors: Nanji KC, Merry AF, Shaikh SD, Pagel C, Deng H, Wahr JA, Gelb AW, Orser BA Abstract INTRODUCTION: Medication errors (MEs), which occur commonly in the perioperative period, have the potential to cause patient harm or death. Many published recommendations exist for preventing perioperative...
Thu Jul 02, 2020 16:37
Related Articles PRImary care Management of lower Urinary tract Symptoms in men: protocol for development and validation of a diagnostic and clinical decision support tool (the PriMUS study). BMJ Open. 2020 Jun 30;10(6):e037634 Authors: Pell B, Thomas-Jones E, Bray A, Agarwal R, Ahmed H, Allen AJ, Clarke S, Deeks JJ, Drake M, Drinnan M, Dyer C, Hood K, Joseph-Williams N, Marsh L, Milosevic S, Pickard R, Schatzberger T, Takwoingi Y, Harding C, Edwards A ...
Thu Jul 02, 2020 16:37
Related Articles Identification of factors associated with morbidity and postoperative length of stay in surgically managed chronic subdural haematoma using electronic health records: a retrospective cohort study. BMJ Open. 2020 Jun 30;10(6):e037385 Authors: Stubbs DJ, Davies BM, Bashford T, Joannides AJ, Hutchinson PJ, Menon DK, Ercole A, Burnstein RM Abstract INTRODUCTION: Chronic subdural haematoma (cSDH) tends to occur in older patients,...
Thu Jul 02, 2020 16:37
Related Articles Social capital and peer influence of tobacco consumption: a cross-sectional study among household heads in rural Uttar Pradesh, India. BMJ Open. 2020 Jun 30;10(6):e037202 Authors: Hasan MZ, Cohen JE, Bishai D, Kennedy CE, Rao KD, Ahuja A, Gupta S Abstract OBJECTIVE: Having the world's second-largest tobacco-consuming population, tobacco control is a priority agenda of the Indian Government. Yet, there is no evidence of how peer...
Thu Jul 02, 2020 16:37
Related Articles Study protocol for the ACT response pilot intervention: development, implementation and evaluation of a systems-based Agitation Code Team (ACT) in the emergency department. BMJ Open. 2020 Jun 30;10(6):e036982 Authors: Wong AH, Ray JM, Auerbach MA, Venkatesh AK, McVaney C, Burness D, Chmura C, Saxa T, Sevilla M, Flood CT, Patel A, Whitfill T, Dziura JD, Yonkers KA, Ulrich A, Bernstein SL Abstract INTRODUCTION: Emergency department...
Thu Jul 02, 2020 16:37
Related Articles Theory-based electronic learning intervention to support appropriate antibiotic prescribing by nurse and pharmacist independent prescribers: an acceptability and feasibility experimental study using mixed methods. BMJ Open. 2020 Jun 30;10(6):e036181 Authors: Lim R, Courtenay M, Deslandes R, Ferriday R, Gillespie D, Hodson K, Reid N, Thomas N, Chater A Abstract OBJECTIVES: To assess the acceptability and feasibility of using...
Thu Jul 02, 2020 16:37
Related Articles Relationship of CT densitometry to lung physiological parameters and health status in alpha-1 antitrypsin deficiency: initial report of a centralised database of the NIHR rare diseases translational research collaborative. BMJ Open. 2020 Jun 30;10(6):e036045 Authors: Crossley D, Stockley J, Bolton CE, Hopkinson NS, Mahadeva R, Steiner M, Wilkinson T, Hurst JR, Gooptu B, Stockley RA Abstract OBJECTIVES: To establish a database...
Thu Jul 02, 2020 16:37
Related Articles Effect of reactive balance training on physical fitness poststroke: study protocol for a randomised non-inferiority trial. BMJ Open. 2020 Jun 30;10(6):e035740 Authors: Barzideh A, Marzolini S, Danells C, Jagroop D, Huntley AH, Inness EL, Mathur S, Mochizuki G, Oh P, Mansfield A Abstract INTRODUCTION: Regular exercise is essential in the chronic phase of stroke recovery for improving or maintaining function, and reducing the...
Thu Jul 02, 2020 16:37
Related Articles Interpretation of China's 2017 health expenditure: a latent profile analysis of panel data. BMJ Open. 2020 Jun 30;10(6):e035512 Authors: Zang S, Zhao M, OuYang J, Wang X Abstract OBJECTIVE: To explore the latent structure of health financing and the institutional distribution of health expenditure (focused on hospital expenditure) in provinces, autonomous regions and municipalities of mainland China, and to examine how these...
Thu Jul 02, 2020 16:37
Related Articles Elastic-band resistance exercise or vibration treatment in combination with hydroxymethylbutyrate (HMB) supplement for management of sarcopenia in older people: a study protocol for a single-blinded randomised controlled trial in Hong Kong. BMJ Open. 2020 Jun 30;10(6):e034921 Authors: Chow SK, Chim YN, Cheng KY, Ho CY, Ho WT, Cheng KC, Wong RM, Cheung WH Abstract INTRODUCTION: Sarcopenia is a geriatric syndrome characterised...
Thu Jul 02, 2020 16:37
Related Articles Risk factors for bleeding in haemato-oncology patients-a nested case-control study: The BITE study protocol (Bleeding In Thrombocytopenia Explained). BMJ Open. 2020 Jun 30;10(6):e034710 Authors: Cornelissen LL, Caram-Deelder C, van der Bom JG, Middelburg RA, Zwaginga JJ Abstract INTRODUCTION: Haemato-oncological patients often receive platelet count driven prophylactic platelet transfusions to prevent bleeding. However, many...
Thu Jul 02, 2020 16:37
Related Articles Supervised treatment in outpatients for schizophrenia plus (STOPS+): protocol for a cluster randomised trial of a community-based intervention to improve treatment adherence and reduce the treatment gap for schizophrenia in Pakistan. BMJ Open. 2020 Jun 30;10(6):e034709 Authors: Shepherd TA, Ul-Haq Z, Ul-Haq M, Khan MF, Afridi A, Dikomitis L, Robinson ME, Lewis M, Rahman A, Dziedzic K, Saeed U, Awan NR, Mallen C, Farooq S Abstract ...
Thu Jul 02, 2020 16:37
Background. Solid pseudopapillary tumor of the pancreas (SPTP) has been reported as a rare disease with low malignant potential. The aim of this study was to summarize experiences of the diagnosis and treatment for the patients reported in the Chinese population. Method. 2450 SPTP cases reported in English and Chinese literature before Jan 2020 were for our review and analysis retrospectively. Result. There are 389 male cases and 2061 female cases, and the ratio of male/female was 1 : 5.3. The average...
Thu Jul 02, 2020 09:50
Lumbar spinal stenosis (LSS) is a common disease in the elderly population; it has been reported that patients with LSS have an abnormal gait pattern due to symptom such as neurogenic intermittent claudication (NIC); however, no detailed reports exist on the plantar pressure distributions in LSS patients with NIC. To analysis the plantar pressure characteristics of LSS patients, the Footscan® pressure system was used to perform dynamic plantar pressure measurements in 20 LSS patients (age, years)...
Thu Jul 02, 2020 09:35
To identify candidate key genes and miRNAs associated with esophageal squamous cell carcinoma (ESCC) development and prognosis, the gene expression profiles and miRNA microarray data including GSE20347, GSE38129, GSE23400, and GSE55856 were downloaded from the Gene Expression Omnibus (GEO) database. Clinical and survival data were retrieved from The Cancer Genome Atlas (TCGA). Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis of differentially expressed genes (DEGs) was analyzed...
Thu Jul 02, 2020 08:50
Background. Enteroviruses (EVs) can cause infections and outbreaks of mild to severe diseases, such as central nervous system (CNS) and systemic infections. The contribution of EVs to acute CNS/systemic infections requiring hospitalization was assessed by analysing data extracted from virology laboratory database. Methods. Real-life data obtained from two molecular virology laboratories located in Northern Italy were retrieved from databases and analysed retrospectively. The queries used to extract...
Thu Jul 02, 2020 08:05
Background. A functional interplay between BAs and microbial composition in gut is a well-documented phenomenon. In bile, this phenomenon is far less studied, and with this report, we describe the interactions between the BAs and microbiota in this complex biological matrix. Methodology. Thirty-seven gallstone disease patients of which twenty-one with Opisthorchis felineus infection were enrolled in the study. The bile samples were obtained during laparoscopic cholecystectomy for gallstone disease...
Thu Jul 02, 2020 07:50
Background. The CHAARTED and LATITUDE trials demonstrated a prolonged overall survival (OS) for metastatic hormone-naïve prostate cancer (mHNPC) patients who receive up-front docetaxel or abiraterone acetate. These studies used their own risk criteria: CHAARTED trial defines high- and low-volume diseases and LATITUDE trial targeting a high-risk disease. The present study explored whether or not the CHAARTED and LATITUDE criteria were useful for predicting the outcome in Japanese bone mHNPC patients,...
Thu Jul 02, 2020 07:35
Felty’s syndrome (FS) is a disorder wherein patients with rheumatoid arthritis develop splenomegaly, neutropenia, and in some cases, portal hypertension without underlying cirrhosis. Esophageal variceal bleeding is a complication of FS in patients with portal hypertension. In contrast to splenectomy, few reports exist on the management of variceal bleeding with endoscopic therapy. Moreover, the long-term outcome has not been reported. We present a patient with esophageal variceal bleeding due to...
Thu Jul 02, 2020 07:05
Objectives. To investigate the diagnostic value of contrast-enhanced ultrasound- (CEUS-) guided contrast injection via an endoscopic nasobiliary drainage (ENBD) tube on the evaluation for residual stones in common bile duct (CBD). Methods. 116 patients with CBD stones were treated by endoscopic retrograde cholangiopancreatography and duodenoscopic sphincterotomy incision surgery and ENBD. The US group consisted of 54 patients who underwent US-guided saline injection via the ENBD tube to evaluate...
Thu Jul 02, 2020 07:05
Background. Acute aortic dissection (AAD) is a devastating cardiovascular disease with a high rate of disability and mortality. This disease often rapidly progresses to fatal multiple organ hypoperfusion, and the incidence has been increasing in recent years. However, the molecular mechanisms have yet to be clarified. This study is aimed at identifying the differential abundance proteins (DAPs) of aortic arch tissues in patients with AAD by proteomics and select possible proteins involved in AAD...
Thu Jul 02, 2020 06:35
Background and Aims. There seems to be a higher risk of ischemic stroke and portal vein thrombosis in liver cirrhosis. Both of them may be associated with hypercoagulability. We aim to explore the association between ischemic stroke and portal vein thrombosis in liver cirrhosis. Study Design and Methods. We selected patients from our prospectively established database of liver cirrhosis from December 2014 to July 2019. The difference between patients with and without stroke was compared. A 1 : 1...
Thu Jul 02, 2020 06:20
Background. Pyroptosis, a novel form of inflammatory programmed cell death, was recently found to be a cause of mucosal barrier defect. In our pervious study, CD147 expression was documented to increase in intestinal tissue of inflammatory bowel disease (IBD). Objective. The aim of this study was to determine the function of serum CD147 in pyroptosis. Methods. The study group consisted of 96 cases. The centration of CD147, IL-1β, and IL-18 levels in serum was assessed by ELISA. Real-time PCR and...
Thu Jul 02, 2020 06:20
Related Articles Perceptions and Responses of Residents to the Nuisance Black Fly Simulium jenningsi (Diptera: Simuliidae) in the Mid-Atlantic United States. J Med Entomol. 2020 Jul 01;: Authors: Wilson-Ounekeo RC, Lamp WO Abstract Current management practices of nuisance black flies are conducted on an area-wide level and rely on the support of the public to implement programs. In Maryland, a vocal group of residents campaigned their representatives...
Thu Jul 02, 2020 16:28
Publication date: Available online 2 July 2020Source: NeuroImageAuthor(s): Jona Carmon, Jil Heege, Joe H. Necus, Thomas W. Owen, Gordon Pipa, Marcus Kaiser, Peter N. Taylor, Yujiang Wang
Thu Jul 02, 2020 16:27
Publication date: Available online 2 July 2020Source: NeuroImageAuthor(s): Laura Pritschet, Tyler Santander, Caitlin M. Taylor, Evan Layher, Shuying Yu, Michael B. Miller, Scott T. Grafton, Emily G. Jacobs
Thu Jul 02, 2020 16:27
Publication date: Available online 2 July 2020Source: Journal of Cranio-Maxillofacial SurgeryAuthor(s): Leandros V. Vassiliou, Julio Acero, Aakshay Gulati, Frank Hölzle, Iain L. Hutchison, Satheesh Prabhu, Sylvie Testelin, Klaus-Dietrich Wolff, Nicholas Kalavrezos, Julio Acero, Aakshay Gulati, Frank Hölzle, Satheesh Prabhu, Sylvie Testelin, Klaus-Dietrich Wolff, Nicholas Kalavrezos
Thu Jul 02, 2020 16:25
Publication date: Available online 1 July 2020Source: Journal of ProteomicsAuthor(s): Benjamin Philipp Ernst, Nadine Wiesmann, Rita Gieringer, Jonas Eckrich, Jürgen Briege
Thu Jul 02, 2020 16:24
Abstract We previously identified that the expression of chitinase‐3‐like protein 1 (CHI3L1) was upregulated during thyroid cancer progression. Here, we investigated the prognostic significance of CHI3L1 expression in thyroid neoplasms and examined the potential oncogenic roles. CHI3L1 immunochemical staining was performed on tissue microarrays of benign and malignant thyroid tumours. Compared with normal thyroid tissue and benign thyroid lesions that had low or no detectable CHI3L1 expression,...
Thu Jul 02, 2020 11:03
Conditions: Cancer of Esophagus; Esophagogastric Junction DisorderIntervention: Sponsors: Heinrich-Heine University, Duesseldorf; University Hospital of CologneNot yet recruiting
Thu Jul 02, 2020 16:17
Condition: Melanoma Stage IVInterventions: Drug: EVX-02A; Drug: EVX-02B; Drug: EVX-02A OR EVX-02BSponsors: Evaxion Biotech ApS; Novotech (Australia) Pty LimitedNot yet recruiting
Thu Jul 02, 2020 16:17
Condition: Nasopharyngeal CarcinomaInterventions: Drug: RT plus Nimotuzumab; Drug: RT plus CisplatinSponsor: Sun Yat-sen UniversityNot yet recruiting
Thu Jul 02, 2020 16:17
Conditions: Breast Carcinoma; Digestive System Neoplasm; Malignant Brain Neoplasm; Malignant Central Nervous System Neoplasm; Malignant Female Reproductive System Neoplasm; Malignant Genitourinary System Neoplasm; Malignant Head and Neck Neoplasm; Malignant Musculoskeletal Neoplasm; Malignant Solid Neoplasm; Metastatic Malignant Neoplasm of Unknown Primary; Skin CarcinomaInterventions: Procedure: Biospecimen Collection; Other: Genetic Counseling; Other: Genetic Testing;...
Thu Jul 02, 2020 16:17
Condition: Squamous Cell Carcinoma of the Head and NeckInterventions: Device: Hemopurifier; Drug: Pembrolizumab 200mg IVSponsor: Aethlon Medical Inc.Not yet recruiting
Wed Jul 01, 2020 19:00
Publication date: Available online 2 July 2020Source: Auris Nasus LarynxAuthor(s): T. Huda, P.D.G. Alexander, B. McGrath, C. Shelton
Thu Jul 02, 2020 16:15
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