In 2015, acute lower respiratory tract infections caused 7.4 deaths per 1000 live births (95% confidence interval [CI], 6.7 to 8.8) worldwide. These infections disproportionately affected children in impoverished areas. The epidemiologic characteristics of pneumonia are changing rapidly as a result…
Thu Jul 02, 2020 03:00
Each year, approximately 920,000 children die from pneumonia before the age of 5 years. Providing greater access to appropriate and effective treatment is an important goal. Treatment of bacterial pneumonia requires an effective antibiotic agent administered in adequate doses for an appropriate…
Thu Jul 02, 2020 03:00
Preterm birth (≤36 completed gestational weeks) is the leading cause of neonatal death, and the risk of neonatal death increases with the degree of preterm birth. However, other factors also influence the risk of neonatal death. In a systematic review of studies involving very preterm infants (≤31…
Thu Jul 02, 2020 03:00
Related Articles A Comparison of 18F-FDG-PET/MRI and 18F-FDG-PET/CT in the Cancer Staging of Locoregional Lymph Nodes. In Vivo. 2020 Jul-Aug;34(4):2029-2032 Authors: Slouka D, Krcal J, Kostlivy T, Hrabacka P, Skalova A, Mirka H, Topolcan O, Kucera R Abstract AIM: The aim of the study was to evaluate the yields of 2-deoxy-2-[18F]-fluoro-D-glucose positron-emission tomography/magnetic resonance imaging (18F-FDG-PET/MRI) and 18F-FDG-PET/computed...
Thu Jul 02, 2020 13:07
Related Articles A Feasibility Study for 3D-printed Poly(methyl methacrylate)-resin Tracheostomy Tube Using a Hamster Cheek Pouch Model. In Vivo. 2020 Jul-Aug;34(4):1749-1758 Authors: Jung H, Lee JS, Lee JH, Park KJ, Lee JJ, Park HS Abstract BACKGROUND/AIM: A three-dimensional (3D) printed tracheostomy tube has potential application for patients who require a specialized tube. The aim of this study was to evaluate the characteristics of...
Thu Jul 02, 2020 13:07
Related Articles Effectiveness of stenting with an intubation tube for a subglottic mass in an infant. BMJ Case Rep. 2020 Jun 30;13(6): Authors: Fujita Y, Hirabayashi H, Imataka G, Yoshihara S PMID: 32606135 [PubMed - in process]
Thu Jul 02, 2020 13:07
Related Articles Feasibility and effectiveness of palliative intensity-modulated radiotherapy for carotid sinus syndrome secondary to recurrent head and neck cancer. BMJ Case Rep. 2020 Jun 30;13(6): Authors: Wada K, Hirata T, Shinoda Y, Teshima T Abstract A 74-year-old man presented with recurrent syncope 3 months after definitive surgery for hypopharyngeal cancer. The patient experienced dizziness and severe hypotension on the movement...
Thu Jul 02, 2020 13:07
Related Articles Intracardiac metastasis from head and neck squamous cell carcinoma. BMJ Case Rep. 2020 Jun 30;13(6): Authors: Abu Khalaf S, Riaz T, Mansour A, Doll D Abstract Cardiac metastasis from head and neck cancer is an extremely rare and devastating condition with an abysmal prognosis. Most of our knowledge about this condition is from case reports and series. We present a case of squamous cell carcinoma of the tonsils that was...
Thu Jul 02, 2020 13:07
Related Articles Case of aggressive metastatic follicular variant papillary thyroid carcinoma with BRAF K601E and BCORL1 mutations. BMJ Case Rep. 2020 Jun 30;13(6): Authors: Attia D, Lurie A, Zhai Q, Smallridge R Abstract BCL6 corepressor like-1 (BCORL1) mutation has rarely been described in thyroid cancer or in association with BRAF mutations in any malignancy. However, we report a 49-year-old woman who had aggressive follicular variant...
Thu Jul 02, 2020 13:07
Related Articles Repurposing the FDA-Approved Antiviral Drug Ribavirin as Targeted Therapy for Nasopharyngeal Carcinoma. Mol Cancer Ther. 2020 Jun 30;: Authors: Huq S, Casaos J, Serra R, Peters M, Xia Y, Ding AS, Ehresman J, Kedda JN, Morales M, Gorelick NL, Zhao T, Ishida W, Perdomo-Pantoja A, Cecia A, Ji C, Suk I, Sidransky D, Brait M, Brem H, Skuli N, Tyler B Abstract Nasopharyngeal carcinoma (NPC) is a squamous cell carcinoma with a...
Thu Jul 02, 2020 13:07
Related Articles Comparison of Panitumumab-IRDye800CW and 5-Aminolevulinic Acid to Provide Optical Contrast in a Model of Glioblastoma Multiforme. Mol Cancer Ther. 2020 Jun 30;: Authors: Warram JM, Napier TS, Udayakumar N, Jani AH, Hartman YE, Houson HA, Moore L, Amm HM, van den Berg NS, Sorace AG Abstract Maximal safe resection of malignant tissue is associated with improved progression-free survival and better response to radiation and...
Thu Jul 02, 2020 13:07
Related Articles Two trajectories of functional recovery in thyroid surgery-related unilateral vocal fold paralysis. Surgery. 2020 Jun 27;: Authors: Pei YC, Lu YA, Wong AMK, Chuang HF, Li HY, Fang TJ Abstract BACKGROUND: Iatrogenic unilateral vocal fold paralysis caused by thyroid surgery induces profound physical and psychosocial distress in patients. The natural course of functional recovery over time differs substantially across subjects,...
Thu Jul 02, 2020 13:07
Related Articles Middle ear adenomatous neuroendocrine tumors: suggestion for surgical strategy. Braz J Otorhinolaryngol. 2020 Jun 15;: Authors: Xie B, Zhang S, Dai C, Liu Y Abstract INTRODUCTION: Middle ear adenomatous neuroendocrine tumors are extremely rare neoplasms with epithelial and neuroendocrine differentiation, accounting for fewer than 2% of all middle and inner ear tumors. Universal standard surgical procedures for different...
Thu Jul 02, 2020 13:07
Related Articles A meta-analysis of pre- and postoperative corticosteroids for reducing the complications following facial reconstructive and aesthetic surgery. Braz J Otorhinolaryngol. 2020 Jun 20;: Authors: Aldhabaan SA, Hudise JY, Obeid AA Abstract INTRODUCTION: Edema and ecchymosis after facial plastic surgery are a troublesome concern for both patients and surgeons. Corticosteroid administration is thought to shorten the recovery period...
Thu Jul 02, 2020 13:07
Related Articles Development of an enhanced acute care surgery service in response to the COVID-19 global pandemic. Injury. 2020 Jun 25;: Authors: Mathur S, Jeremy Ng CF, Koh F, Cai M, Palaniappan G, Linn YL, Lim HL, Lakshman R, Ling XS, Chin ST, Tan HK Abstract BACKGROUND: As the COVID-19 pandemic sweeps across the world, healthcare departments must adapt to meet the challenges of service provision and staff/patient protection. Unlike...
Thu Jul 02, 2020 13:07
Related Articles Association between the NOS2 pentanucleotide repeat polymorphism and risk of postoperative recurrence of chronic rhinosinusitis with nasal polyps in a Japanese population. Allergol Int. 2020 Jun 27;: Authors: Kidoguchi M, Yoshida K, Noguchi E, Nakamura T, Morii W, Haruna T, Okano M, Yamashita Y, Haruna S, Hasegawa M, Yoshida N, Ninomiya T, Imoto Y, Sakashita M, Takabayashi T, Fujieda S PMID: 32605765 [PubMed - as supplied by publisher]
Thu Jul 02, 2020 13:07
Related Articles Ex utero intrapartum treatment to extracorporeal membrane oxygenation: lifesaving management of a giant cervical teratoma. J Laryngol Otol. 2020 Jul 01;:1-4 Authors: Reeve NH, Kahane JB, Spinner AG, O-Lee TJ Abstract BACKGROUND: Ex utero intrapartum treatment ('EXIT' procedure) is a well described method for maintaining maternal-fetal circulation in the setting of airway obstruction from compressive neck masses. When ex...
Thu Jul 02, 2020 13:07
Related Articles Reusable respirators as personal protective equipment during ENT surgery. J Laryngol Otol. 2020 Jul 01;:1-6 Authors: Patel B, Hardman JC, Yang W, Robson A, Putnam G, George A, Paleri V PMID: 32605665 [PubMed - as supplied by publisher]
Thu Jul 02, 2020 13:07
Related Articles The efficacy of different treatment approaches for pediatric OSAHS patients with mandibular retrognathia: study protocol for a multicenter randomized controlled trial. Trials. 2020 Jun 30;21(1):595 Authors: Li Y, Wu J, Guo J, Yu L, Wang J, Li X, Xu S, Zhu M, Feng J, Liu Y Abstract BACKGROUND: Pediatric obstructive sleep apnea/hypopnea syndrome (OSAHS) is a multifactorial syndrome caused by many risk factors, such as craniofacial...
Thu Jul 02, 2020 13:07
Related Articles Index of Cancer-Associated Fibroblasts Is Superior to the Epithelial-Mesenchymal Transition Score in Prognosis Prediction. Cancers (Basel). 2020 Jun 28;12(7): Authors: Ko YC, Lai TY, Hsu SC, Wang FH, Su SY, Chen YL, Tsai ML, Wu CC, Hsiao JR, Chang JY, Wu YM, Robinson DR, Lin CY, Lin SF Abstract In many solid tumors, tissue of the mesenchymal subtype is frequently associated with epithelial-mesenchymal transition (EMT),...
Thu Jul 02, 2020 13:07
Related Articles The Intermediate Filament Synemin Regulates Non-Homologous End Joining in an ATM-Dependent Manner. Cancers (Basel). 2020 Jun 28;12(7): Authors: Deville SS, Vehlow A, Förster S, Dickreuter E, Borgmann K, Cordes N Abstract The treatment resistance of cancer cells is a multifaceted process in which DNA repair emerged as a potential therapeutic target. DNA repair is predominantly conducted by nuclear events; yet, how extra-nuclear...
Thu Jul 02, 2020 13:07
Related Articles Voice-Related Quality of Life in Post-Laryngectomy Rehabilitation: Tracheoesophageal Fistula's Wellness. Int J Environ Res Public Health. 2020 Jun 26;17(12): Authors: Cocuzza S, Maniaci A, Grillo C, Ferlito S, Spinato G, Coco S, Merlino F, Stilo G, Santoro GP, Iannella G, Vicini C, La Mantia I Abstract (1) Introduction: Laryngeal cancer is one of the most common types of cancer affecting the upper aerodigestive tract. Despite...
Thu Jul 02, 2020 13:07
Related Articles Associations between Particulate Matter and Otitis Media in Children: A Meta-Analysis. Int J Environ Res Public Health. 2020 Jun 26;17(12): Authors: Lee SY, Jang MJ, Oh SH, Lee JH, Suh MW, Park MK Abstract Particulate matter (PM), a primary component of air pollution, is a suspected risk factor for the development of otitis media (OM). However, the results of studies on the potential correlation between an increase in the...
Thu Jul 02, 2020 13:07
Related Articles The Value of Laboratory Parameters for Anemia, Renal Function, Systemic Inflammation and Nutritional Status as Predictors for Outcome in Elderly Patients with Head-and-Neck Cancers. Cancers (Basel). 2020 Jun 26;12(6): Authors: Rühle A, Haehl E, David H, Kalckreuth T, Sprave T, Stoian R, Zamboglou C, Gkika E, Knopf A, Grosu AL, Nicolay NH Abstract The purpose of this study was to evaluate the value of routine blood markers...
Thu Jul 02, 2020 13:07
Related Articles Vagal Nerve Stimulation: Indications, Implantation, and Outcomes. Otolaryngol Clin North Am. 2020 Feb;53(1):127-143 Authors: Ohemeng KK, Parham K Abstract Vagal nerve stimulation (VNS) therapy is a surgical treatment that involves the implantation of a device to electrically stimulate the vagus nerve. It is indicated as an adjunctive treatment of epilepsy that is refractory to antiepileptic medications and for treatment-resistant...
Thu Jul 02, 2020 13:07
Related Articles Cochlear Implant. Otolaryngol Clin North Am. 2020 Feb;53(1):87-102 Authors: Naples JG, Ruckenstein MJ Abstract Cochlear implant is the first approved cranial nerve stimulator that works by directly stimulating the cochlear nerve. The medical and societal impact of this revolutionary device cannot be understated. This article reviews the evolving indications for cochlear implant, patient assessment, surgical approach, and outcomes...
Thu Jul 02, 2020 13:07
Related Articles Vestibular Implantation and the Feasibility of Fluoroscopy-Guided Electrode Insertion. Otolaryngol Clin North Am. 2020 Feb;53(1):115-126 Authors: Stultiens JJA, Postma AA, Guinand N, Pérez Fornos A, Kingma H, van de Berg R Abstract Recent research has shown promising results for the development of a clinically feasible vestibular implant in the near future. However, correct electrode placement remains a challenge. It was...
Thu Jul 02, 2020 13:07
Related Articles Central Effects of Cranial Nerve Stimulation. Otolaryngol Clin North Am. 2020 Feb;53(1):45-55 Authors: Kohlberg GD, Samy RN Abstract The current literature on peripheral cranial nerve stimulation for the purpose of achieving therapeutic effects via altering brain activity is reviewed. Vagus nerve stimulation, which is approved for use in refractory epilepsy, is the most extensively studied cranial nerve stimulator that has...
Thu Jul 02, 2020 13:07
Related Articles Auditory Brainstem Implantation: Candidacy Evaluation, Operative Technique, and Outcomes. Otolaryngol Clin North Am. 2020 Feb;53(1):103-113 Authors: Deep NL, Roland JT Abstract Auditory brainstem implants (ABIs) stimulate the auditory system at the cochlear nucleus, bypassing the peripheral auditory system including the auditory nerve. They are used in patients who are not cochlear implant candidates. Current criteria for...
Thu Jul 02, 2020 13:07
Related Articles Lingual Squamous Cell Carcinoma in Two Horses. J Equine Vet Sci. 2019 08;79:35-38 Authors: Morrison ML, Groover E, Schumacher J, Newton J, Pereira MM Abstract Squamous cell carcinoma (SCC) is one of the most common malignant neoplasms in horses, but lingual SCC has seldom been reported. On separate occasions, a 12-year-old American Quarter Horse mare and an 18-year-old American Saddlebred stallion were presented to the...
Thu Jul 02, 2020 13:07
The commonest etiologies of new-onset pancytopenia are congenital bone marrow failure syndromes, marrow space-occupying lesions, infections, and peripheral destruction. Nutritional deficiencies, including folate and vitamin B12, can occasionally cause pancytopenia. We report a 48-year-old gentleman who presented with a 1-week history of dizziness and upper gastrointestinal bleeding. Laboratory evaluation revealed pancytopenia, macrocytosis, toxic neutrophils, hemolysis, suppressed reticulocyte count,...
Thu Jul 02, 2020 10:53
Mantle cell lymphoma (MCL) is a relatively rare B-cell non-Hodgkin lymphoma, typically presenting with extensive lymphadenopathy, bone marrow involvement, and splenomegaly. Extranodal sites can also be involved. We discuss a 73-year-old man whose MCL presented with a 6-month history of a subdermal mass of the right upper thigh and no systemic symptoms. Case Rep Oncol 2020;13:774–782
Thu Jul 02, 2020 10:53
The regimen of oxaliplatin with 5-fluorouracil plus l-leucovorin (FOLFOX) has become one of the most commonly used first-line chemotherapy for patients with advanced colorectal cancer and it provides an increase in disease-free survival as well as an overall survival benefit. Although FOLFOX chemotherapy has helped to improve the clinical outcomes in these patients, the regimen is associated with some therapeutic issues or uncontrolled side effects. Gastrointestinal, neurosensory, and hematological...
Thu Jul 02, 2020 09:32
A Case of Retroperitoneal Ganglioneuroma Accidentally Discovered by Laparoscopic Right Adrenalectomy
A 65-year-old man was referred to our hospital for his right adrenal adenoma. Adrenal vein blood sampling revealed primary hyperaldosteronism, and he was referred to our department for surgical resection of his right adenoma. During the operation, a small nodule was discovered in addition to the adrenal tumor. The pathological diagnosis of this nodule was ganglioneuroma. We herein report a rare case of ganglioneuroma incidentally discovered by laparoscopic right adrenalectomy. Case Rep Oncol 2020;13:764–767
Thu Jul 02, 2020 09:31
Related Articles Efficacy of Gefitinib Combined with 125I Radioactive Particles in the Treatment of Transplanted Lung Cancer Tumors in Nude Mice. Cardiovasc Intervent Radiol. 2020 Jun 30;: Authors: Li C, Yao L, Gong J, Pang H, Shan Q, Wang Z, Lu J, Wang Z Abstract OBJECTIVE: To investigate the efficacy of gefitinib combined with iodine-125 (125I) radioactive particles in the treatment of transplanted tumors of the lung cancer cell line...
Thu Jul 02, 2020 13:05
Related Articles Clinicopathological characterization and prognostic implication of FOXP3 and CK19 expression in papillary thyroid carcinoma and concomitant Hashimoto's thyroiditis. Sci Rep. 2020 Jun 30;10(1):10651 Authors: Mohamed SY, Ibrahim TR, Elbasateeny SS, Abdelaziz LA, Farouk S, Yassin MA, Embaby A Abstract Papillary thyroid carcinoma (PTC) is considered the most prevalent thyroid malignancy. The association between Hashimoto's...
Thu Jul 02, 2020 13:05
Related Articles Comparison of survival outcomes between laparoscopic and open surgery in patients with low-risk endometrial cancer. Jpn J Clin Oncol. 2020 Jul 01;: Authors: Togami S, Kawamura T, Yanazume S, Kamio M, Kobayashi H Abstract OBJECTIVE: To evaluate the feasibility, safety and surgical outcomes of laparoscopic surgery for the treatment of low-risk endometrial cancer. METHODS: Of 155 patients with low-risk endometrial cancer,...
Thu Jul 02, 2020 13:00
Related Articles Diagnose of glioma using 68Ga-PSMA and 18F-FDG PET/MRI. Jpn J Clin Oncol. 2020 Jul 01;: Authors: Zhang X, Yuan J, Zhou C, Fan W PMID: 32607582 [PubMed - as supplied by publisher]
Thu Jul 02, 2020 13:00
Related Articles Massive anterior extraocular extension of choroidal melanoma through the cornea. Jpn J Clin Oncol. 2020 Jul 01;: Authors: Sachdev A, Ahluwalia H PMID: 32607553 [PubMed - as supplied by publisher]
Thu Jul 02, 2020 13:00
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