Antibiotics, Vol. 9, Pages 481: Antimicrobial Resistance Patterns in Clostridioides difficile Strains Isolated from Neonates in Germany Antibiotics doi: 10.3390/antibiotics9080481 Authors: Tilkorn Frickmann Simon Schwanbeck Horn Zimmermann Groß Bohne Zautner Young children are frequently colonized with Clostridioides (C.) difficile. Depending on their resistance patterns, antibiotic treatment can facilitate gastrointestinal spreading in colonized individuals,...
Tue Aug 04, 2020 03:00
Antibiotics, Vol. 9, Pages 478: Lactobacillus Plantarum 108 Inhibits Streptococcus mutans and Candida albicans Mixed-Species Biofilm Formation Antibiotics doi: 10.3390/antibiotics9080478 Authors: Srivastava Ellepola Venkiteswaran Chai Ohshima Seneviratne Streptococcus mutans is the principal biofilm forming oral pathogen associated with dental caries. Studies have shown that Candida albicans, a commensal oral fungus is capable of forming pathogenic mixed-species...
Tue Aug 04, 2020 03:00
Antibiotics, Vol. 9, Pages 479: Analysing the Relationship between Nutrition and the Microbial Composition of the Oral Biofilm—Insights from the Analysis of Individual Variability Antibiotics doi: 10.3390/antibiotics9080479 Authors: Kirstin Vach Ali Al-Ahmad Annette Anderson Johan Peter Woelber Lamprini Karygianni Annette Wittmer Elmar Hellwig The influence of a change in nutrition on the oral microbiota are discussed in literature, but usually only changes of population...
Tue Aug 04, 2020 03:00
Antibiotics, Vol. 9, Pages 480: Plant-Based Phytochemicals as Possible Alternative to Antibiotics in Combating Bacterial Drug Resistance Antibiotics doi: 10.3390/antibiotics9080480 Authors: AlSheikh Sultan Kumar Rather Al-Sheikh Tasleem Jan Haq The unprecedented use of antibiotics that led to development of resistance affect human health worldwide. Prescription of antibiotics imprudently and irrationally in different diseases progressed with the acquisition and...
Tue Aug 04, 2020 03:00
Antibiotics, Vol. 9, Pages 477: Risk of Antimicrobial Resistant Non-Typhoidal Salmonella during Asymptomatic Infection Passage between Pet Dogs and Their Human Caregivers in Khon Kaen, Thailand Antibiotics doi: 10.3390/antibiotics9080477 Authors: Xin Wu Sunpetch Angkititrakul Allen L. Richards Chaiwat Pulsrikarn Seri Khaengair Amphone Keosengthong Supatcharee Siriwong Fanan Suksawat To explore the risk of antimicrobial resistant (AMR) non-typhoidal Salmonella during...
Tue Aug 04, 2020 03:00
Antibodies, Vol. 9, Pages 38: Is the Host Viral Response and the Immunogenicity of Vaccines Altered in Pregnancy? Antibodies doi: 10.3390/antib9030038 Authors: Zainab Saeed Orene Greer Nishel Mohan Shah The intricacy of the maternal immune system arises from its ability to prevent a maternal immune response against a semi-allogenic fetus, while protecting the mother against harmful pathogens. However, these immunological adaptations may also make pregnant women vulnerable to developing...
Tue Aug 04, 2020 03:00
Antioxidants, Vol. 9, Pages 707: Oxidative Stress, Antioxidant Capabilities, and Bioavailability: Ellagic Acid or Urolithins? Antioxidants doi: 10.3390/antiox9080707 Authors: Alfei Marengo Zuccari This review focuses on the pathophysiology of OS; on EA and UROs chemical features and on the mechanisms of their antioxidant activity. A discussion on the clinical applicability of the debated UROs in place of EA and on the effectiveness of EA-enriched products is also included.
Tue Aug 04, 2020 03:00
Antioxidants, Vol. 9, Pages 706: Lycopene as a Natural Antioxidant Used to Prevent Human Health Disorders Antioxidants doi: 10.3390/antiox9080706 Authors: Imran Ghorat Ul-Haq Ur-Rehman Aslam Heydari Shariati Okuskhanova Yessimbekov Thiruvengadam Hashempur Rebezov Lycopene, belonging to the carotenoids, is a tetraterpene compound abundantly found in tomato and tomato-based products. It is fundamentally recognized as a potent antioxidant and...
Tue Aug 04, 2020 03:00
Antioxidants, Vol. 9, Pages 705: Extracellular Vesicles and MicroRNA: Putative Role in Diagnosis and Treatment of Diabetic Retinopathy Antioxidants doi: 10.3390/antiox9080705 Authors: Beatriz Martins Madania Amorim Flávio Reis António Francisco Ambrósio Rosa Fernandes Diabetic retinopathy (DR) is a complex, progressive, and heterogenous retinal degenerative disease associated with diabetes duration. It is characterized by glial, neural, and microvascular dysfunction, being...
Tue Aug 04, 2020 03:00
Antioxidants, Vol. 9, Pages 708: New Insights into the Exploitation of Vitis vinifera L. cv. Aglianico Leaf Extracts for Nutraceutical Purposes Antioxidants doi: 10.3390/antiox9080708 Authors: Fabiana Labanca Immacolata Faraone Maria Rosaria Nolè Ruth Hornedo-Ortega Daniela Russo Maria Carmen García-Parrilla Lucia Chiummiento Maria Grazia Bonomo Luigi Milella The leaves of Vitis vinifera L. have been used for a long time in traditional medicine for the treatment...
Tue Aug 04, 2020 03:00
Antioxidants, Vol. 9, Pages 704: Antioxidants and Skin Protection Antioxidants doi: 10.3390/antiox9080704 Authors: María Herranz-López Enrique Barrajón-Catalán Natural products have a long history of use for skincare and the improvement of the appearance and function of aged and/or damaged skin [...]
Tue Aug 04, 2020 03:00
Atmosphere, Vol. 11, Pages 821: A Challenging Tornado Forecast in Slovakia Atmosphere doi: 10.3390/atmos11080821 Authors: Šinger Púčik An F1 tornado hit the village of Lekárovce in eastern Slovakia on the afternoon of 3 October 2018. The tornado, which occurred outside the main convective season in Slovakia, was not anticipated by the meteorologists of the Slovak Hydrometeorological Institute. The models available to the forecasters simulated an environment of marginal...
Tue Aug 04, 2020 03:00
Atmosphere, Vol. 11, Pages 823: Prediction Skill of Extended Range 2-m Maximum Air Temperature Probabilistic Forecasts Using Machine Learning Post-Processing Methods Atmosphere doi: 10.3390/atmos11080823 Authors: Ting Peng Xiefei Zhi Yan Ji Luying Ji Ye Tian The extended range temperature prediction is of great importance for public health, energy and agriculture. The two machine learning methods, namely, the neural networks and natural gradient boosting (NGBoost), are applied...
Tue Aug 04, 2020 03:00
Atmosphere, Vol. 11, Pages 822: Future Changes in Euro-Mediterranean Daytime Severe Thunderstorm Environments Based on an RCP8.5 Med-CORDEX Simulation Atmosphere doi: 10.3390/atmos11080822 Authors: Abdullah Kahraman Deniz Ural Barış Önol Convective scale processes and, therefore, thunderstorm-related hazards cannot be simulated using regional climate models with horizontal grid spacing in the order of 10 km. However, larger-scale environmental conditions of these local high-impact...
Tue Aug 04, 2020 03:00
Atmosphere, Vol. 11, Pages 820: Characterization of Atmospheric PM2.5 Inorganic Aerosols Using the Semi-Continuous PPWD-PILS-IC System and the ISORROPIA-II Atmosphere doi: 10.3390/atmos11080820 Authors: Thi-Cuc Le Yun-Chin Wang David Y. H. Pui Chuen-Jinn Tsai A semi-continuous monitoring system, a parallel plate wet denuder and particle into liquid sampler coupled with ion chromatography (PPWD-PILS-IC), was used to measure the hourly precursor gases and water-soluble inorganic...
Tue Aug 04, 2020 03:00
Behavioral Sciences, Vol. 10, Pages 126: Mathematical Profile Test: A Preliminary Evaluation of an Online Assessment for Mathematics Skills of Children in Grades 1–6 Behavioral Sciences doi: 10.3390/bs10080126 Authors: Giannis Karagiannakis Marie-Pascale Noël The domain of numerical cognition still lacks an assessment tool that is theoretically driven and that covers a wide range of key numerical processes with the aim of identifying the learning profiles of children with difficulties...
Tue Aug 04, 2020 03:00
Bioengineering, Vol. 7, Pages 86: Implementation of Endogenous and Exogenous Mesenchymal Progenitor Cells for Skeletal Tissue Regeneration and Repair Bioengineering doi: 10.3390/bioengineering7030086 Authors: Salomi Desai Chathuraka Jayasuriya Harnessing adult mesenchymal stem/progenitor cells to stimulate skeletal tissue repair is a strategy that is being actively investigated. While scientists continue to develop creative and thoughtful ways to utilize these cells for tissue repair,...
Tue Aug 04, 2020 03:00
Biology, Vol. 9, Pages 205: Kinetics of Enzymatic Synthesis of Cyanidin-3-Glucoside Lauryl Ester and Its Physicochemical Property and Proliferative Effect on Intestinal Probiotics Biology doi: 10.3390/biology9080205 Authors: Xi Yang Hanju Sun Lijun Tu Yuan Jin Zuoyong Zhang Muwen Wang Shuyun Liu Ying Wang Shudong He The interest in anthocyanins used in food, cosmetic, and pharmaceutical industries has increased the research in order to improve their stability...
Tue Aug 04, 2020 03:00
Biology, Vol. 9, Pages 206: Salvia Spp. Essential Oils against the Arboviruses Vector Aedes albopictus (Diptera: Culicidae): Bioactivity, Composition, and Sensorial Profile—Stage 1 Biology doi: 10.3390/biology9080206 Authors: Basma Najar Luisa Pistelli Francesca Venturi Giuseppe Ferroni Silvia Giovanelli Claudio Cervelli Stefano Bedini Barbara Conti Mosquito-borne arboviruses diseases cause a substantial public health burden within their expanding range. To date,...
Tue Aug 04, 2020 03:00
Biomedicines, Vol. 8, Pages 272: Transmissible Endosomal Intoxication: A Balance between Exosomes and Lysosomes at the Basis of Intercellular Amyloid Propagation Biomedicines doi: 10.3390/biomedicines8080272 Authors: Anaïs Bécot Charlotte Volgers Guillaume van Niel In Alzheimer′s disease (AD), endolysosomal dysfunctions are amongst the earliest cellular features to appear. Each organelle of the endolysosomal system, from the multivesicular body (MVB) to the lysosome,...
Tue Aug 04, 2020 03:00
Biomolecules, Vol. 10, Pages 1144: Long QT Syndrome Type 2: Emerging Strategies for Correcting Class 2 KCNH2 (hERG) Mutations and Identifying New Patients Biomolecules doi: 10.3390/biom10081144 Authors: Makoto Ono Don E. Burgess Elizabeth A. Schroder Claude S. Elayi Corey L. Anderson Craig T. January Bin Sun Kalyan Immadisetty Peter M. Kekenes-Huskey Brian P. Delisle Significant advances in our understanding of the molecular mechanisms that cause congenital...
Tue Aug 04, 2020 03:00
Biomolecules, Vol. 10, Pages 1143: Post-Translational Regulation of ARF: Perspective in Cancer Biomolecules doi: 10.3390/biom10081143 Authors: Jinho Seo Daehyeon Seong Seung Ri Lee Doo-Byoung Oh Jaewhan Song Tumorigenesis can be induced by various stresses that cause aberrant DNA mutations and unhindered cell proliferation. Under such conditions, normal cells autonomously induce defense mechanisms, thereby stimulating tumor suppressor activation. ARF, encoded by the CDKN2a...
Tue Aug 04, 2020 03:00
Biomolecules, Vol. 10, Pages 1141: Co-Chaperones in Targeting and Delivery of Misfolded Proteins to the 26S Proteasome Biomolecules doi: 10.3390/biom10081141 Authors: Amanda B. Abildgaard Sarah K. Gersing Sven Larsen-Ledet Sofie V. Nielsen Amelie Stein Kresten Lindorff-Larsen Rasmus Hartmann-Petersen Protein homeostasis (proteostasis) is essential for the cell and is maintained by a highly conserved protein quality control (PQC) system, which triages newly synthesized,...
Tue Aug 04, 2020 03:00
Biomolecules, Vol. 10, Pages 1142: Distinct Calcium Binding and Structural Properties of Two Centrin Isoforms from Toxoplasma gondii Biomolecules doi: 10.3390/biom10081142 Authors: Luca Bombardi Marco Pedretti Carolina Conter Paola Dominici Alessandra Astegno Centrins are calcium (Ca2+)-binding proteins that have been implicated in several regulatory functions. In the protozoan parasite Toxoplasma gondii, the causative agent of toxoplasmosis, three isoforms of centrin have...
Tue Aug 04, 2020 03:00
Brain Sciences, Vol. 10, Pages 516: Novel Instruments for Percutaneous Biportal Endoscopic Spine Surgery for Full Decompression and Dural Management: A Comparative Analysis Brain Sciences doi: 10.3390/brainsci10080516 Authors: Young-Ho Hong Seung-Kook Kim Dong-Won Suh Su-Chan Lee Background: Post-laminectomy syndrome is a common cause of dissatisfaction after endoscopic interlaminar approach. Our aim was to evaluate the efficacy and safety of our two newly designed instruments...
Tue Aug 04, 2020 03:00
Cancers, Vol. 12, Pages 2170: Contrast-Enhanced Ultrasound (CEUS) for Follow-Up of Bosniak 2F Complex Renal Cystic Lesions—A 12-Year Retrospective Study in a Specialized European Center Cancers doi: 10.3390/cancers12082170 Authors: Johannes Rübenthaler Saša Čečatka Matthias Frank Froelich Matthias Stechele Constantin Marschner Bastian Oliver Sabel Florian Bogner Moritz Ludwig Schnitzer Daniel Overhoff Nils Große Hokamp Michael Staehler Vincent Schwarze Dirk-André...
Tue Aug 04, 2020 03:00
Cancers, Vol. 12, Pages 2169: Identification of Cardiac Glycosides as Novel Inhibitors of eIF4A1-Mediated Translation in Triple-Negative Breast Cancer Cells Cancers doi: 10.3390/cancers12082169 Authors: Cory M. Howard Matthew Estrada David Terrero Amit K. Tiwari Dayanidhi Raman The eukaryotic translation initiation factor 4F complex (eIF4F) is a potential chemotherapeutic target in triple-negative breast cancer (TNBC). This complex regulates cap-dependent translational initiation...
Tue Aug 04, 2020 03:00
Cancers, Vol. 12, Pages 2168: Genetic Engineering of Zebrafish in Cancer Research Cancers doi: 10.3390/cancers12082168 Authors: Ludivine Raby Pamela Völkel Xuefen Le Bourhis Pierre-Olivier Angrand Zebrafish (Danio rerio) is an excellent model to study a wide diversity of human cancers. In this review, we provide an overview of the genetic and reverse genetic toolbox allowing the generation of zebrafish lines that develop tumors. The large spectrum of genetic tools enables...
Tue Aug 04, 2020 03:00
Cancers, Vol. 12, Pages 2162: Perspectives on the Role of Non-Coding RNAs in the Regulation of Expression and Function of the Estrogen Receptor Cancers doi: 10.3390/cancers12082162 Authors: Mohammad Taheri Hamed Shoorei Marcel E. Dinger Soudeh Ghafouri-Fard Estrogen receptors (ERs) comprise several nuclear and membrane-bound receptors with different tissue-specific functions. ERα and ERβ are two nuclear members of this family, whereas G protein-coupled estrogen...
Tue Aug 04, 2020 03:00
Cancers, Vol. 12, Pages 2166: Lymphotropic Viruses EBV, KSHV and HTLV in Latin America: Epidemiology and Associated Malignancies. A Literature-Based Study by the RIAL-CYTED Cancers doi: 10.3390/cancers12082166 Authors: Paola Chabay Daniela Lens Rocio Hassan Socorro María Rodríguez Pinilla Fabiola Valvert Gamboa Iris Rivera Fuad Huamán Garaicoa Stella Maris Ranuncolo Carlos Barrionuevo Abigail Morales Sánchez Vanesa Scholl Elena De Matteo Ma. Victoria...
Tue Aug 04, 2020 03:00
Cancers, Vol. 12, Pages 2165: Laryngeal Mid-Cord Erythroleukoplakias: How to Modulate the Transoral CO2 Laser Excisional Biopsy Cancers doi: 10.3390/cancers12082165 Authors: Francesco Mora Filippo Carta Francesco Missale Andrea Laborai Giampiero Parrinello Cesare Piazza Roberto Puxeddu Giorgio Peretti Background: The endoscopic appearance of glottic erythroleukoplakias is non-predictive of their histopathology, potentially ranging from keratosis to invasive squamous...
Tue Aug 04, 2020 03:00
Cancers, Vol. 12, Pages 2167: Multiple Myeloma-Derived Extracellular Vesicles Induce Osteoclastogenesis through the Activation of the XBP1/IRE1α Axis Cancers doi: 10.3390/cancers12082167 Authors: Lavinia Raimondi Angela De Luca Simona Fontana Nicola Amodio Viviana Costa Valeria Carina Daniele Bellavia Stefania Raimondo Sergio Siragusa Francesca Monteleone Riccardo Alessandro Milena Fini Gianluca Giavaresi Bone disease severely affects the quality of...
Tue Aug 04, 2020 03:00
Cancers, Vol. 12, Pages 2160: The Pathologic and Molecular Landscape of Esophageal Squamous Cell Carcinogenesis Cancers doi: 10.3390/cancers12082160 Authors: Gianluca Businello Paola Parente Luca Mastracci Gianmaria Pennelli Giulia Traverso Massimo Milione Elena Bellan Mauro Michelotto Andromachi Kotsafti Federica Grillo Matteo Fassan Esophageal squamous cell carcinoma represents the most common histotype of epithelial neoplasm occurring within esophageal...
Tue Aug 04, 2020 03:00
Cancers, Vol. 12, Pages 2163: The Curcumin Analogue, EF-24, Triggers p38 MAPK-Mediated Apoptotic Cell Death via Inducing PP2A-Modulated ERK Deactivation in Human Acute Myeloid Leukemia Cells Cancers doi: 10.3390/cancers12082163 Authors: Pei-Ching Hsiao Jer-Hwa Chang Wei-Jiunn Lee Chia-Chi Ku Meng-Ying Tsai Shun-Fa Yang Ming-Hsien Chien Curcumin (CUR) has a range of therapeutic benefits against cancers, but its poor solubility and low bioavailability limit its clinical...
Tue Aug 04, 2020 03:00
Cancers, Vol. 12, Pages 2161: A New Inhibitor of Tubulin Polymerization Kills Multiple Cancer Cell Types and Reveals p21-Mediated Mechanism Determining Cell Death after Mitotic Catastrophe Cancers doi: 10.3390/cancers12082161 Authors: Mykola Zdioruk Andrew Want Anna Mietelska-Porowska Katarzyna Laskowska-Kaszub Joanna Wojsiat Agata Klejman Ewelina Użarowska Paulina Koza Sylwia Olejniczak Stanislaw Pikul Witold Konopka Jakub Golab Urszula Wojda Induction...
Tue Aug 04, 2020 03:00
Cancers, Vol. 12, Pages 2159: The Prowess of Andrographolide as a Natural Weapon in the War against Cancer Cancers doi: 10.3390/cancers12082159 Authors: Ammad Ahmad Farooqi Rukset Attar Uteuliyev Yerzhan Sabitaliyevich Nada Alaaeddine Damião Pergentino de Sousa Baojun Xu William C. Cho There has been a paradigm shift in our understanding about the multifaceted nature of cancer and a wealth of information has revealed that single-target drugs are not good enough to provide...
Tue Aug 04, 2020 03:00
Cancers, Vol. 12, Pages 2164: Molecular Markers Guiding Thyroid Cancer Management Cancers doi: 10.3390/cancers12082164 Authors: Carolina Nylén Robert Mechera Isabella Maréchal-Ross Venessa Tsang Angela Chou Anthony J. Gill Roderick J. Clifton-Bligh Bruce G. Robinson Mark S. Sywak Stan B. Sidhu Anthony R. Glover The incidence of thyroid cancer is rapidly increasing, mostly due to the overdiagnosis and overtreatment of differentiated thyroid cancer (TC). The...
Tue Aug 04, 2020 03:00
Cancers, Vol. 12, Pages 2155: The Role of Steroid Hormone Receptors in Urothelial Tumorigenesis Cancers doi: 10.3390/cancers12082155 Authors: Hiroki Ide Hiroshi Miyamoto Preclinical and/or clinical evidence has indicated a potential role of steroid hormone-mediated signaling pathways in the development of various neoplastic diseases, while precise mechanisms for the functions of specific receptors remain poorly understood. Specifically, in urothelial cancer where sex-related differences...
Tue Aug 04, 2020 03:00
Cancers, Vol. 12, Pages 2157: MDM2-Dependent Rewiring of Metabolomic and Lipidomic Profiles in Dedifferentiated Liposarcoma Models Cancers doi: 10.3390/cancers12082157 Authors: Andrew Patt Bryce Demoret Colin Stets Kate-Lynn Bill Philip Smith Anitha Vijay Andrew Patterson John Hays Mindy Hoang James L. Chen Ewy A. Mathé Dedifferentiated liposarcoma (DDLPS) is an aggressive mesenchymal cancer marked by amplification of MDM2, an inhibitor of the tumor suppressor...
Tue Aug 04, 2020 03:00
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