Improved Beta Cell Glucose Sensitivity Plays Predominant Role in the Decrease in HbA1c with Cana and Lira in T2DM. J Clin Endocrinol Metab. 2020 Aug 03;: Authors: Ali AM, Mari A, Martinez R, Al-Jobori H, Adams J, Triplitt C, DeFronzo R, Cersosimo E, Abdul-Ghani M Abstract AIM: To examine the effect of combination therapy with canagliflozin plus liraglutide versus each agent alone on beta cell function in type 2 diabetes mellitus (T2DM) patients....
Tue Aug 04, 2020 16:36
Related Articles The ecological cocktail party: Measuring brain activity during an auditory oddball task with background noise. Psychophysiology. 2019 11;56(11):e13435 Authors: Scanlon JEM, Cormier DL, Townsend KA, Kuziek JWP, Mathewson KE Abstract Most experiments using EEG recordings take place in highly isolated and restricted environments, limiting their applicability to real-life scenarios. New technologies for mobile EEG are changing...
Tue Aug 04, 2020 13:24
Eosinophilic Otitis Media-An Otitis Media Mandating a Different Outlook. Ear Nose Throat J. 2020 Aug 03;:145561320947269 Authors: Varghese L, Philip A, Suryawanshi MK, Job A PMID: 32744905 [PubMed - as supplied by publisher]
Tue Aug 04, 2020 14:00
Intraductal Papilloma Arising From the Minor Salivary Glands of the Larynx: A Case Report. Ear Nose Throat J. 2020 Aug 03;:145561320944638 Authors: Hara S, Ohba S, Arakawa A, Matsumoto F, Ito S, Fujimaki M, Kojima M, Ikeda K Abstract It is rare for intraductal papilloma, a benign papillary tumor, to occur in the salivary glands. To our knowledge, intraductal papilloma occurring in the minor salivary glands of the larynx has not been reported....
Tue Aug 04, 2020 14:00
Cervical Nodal Metastatic Pituitary Carcinoma: A Case Report. Ear Nose Throat J. 2020 Aug 03;:145561320944649 Authors: Kwok MM, Virk JS, Michael M, McKinley M, Magarey MJR Abstract Pituitary carcinomas are rare tumors with only 170 cases reported in the literature.1 They form a very small proportion of pituitary tumors, which are commonly benign adenomas. Metastatic disease diagnosed by fine needle aspiration cytology is extremely rare...
Tue Aug 04, 2020 14:00
Superficial Parotidectomy: Impact of Postoperative Drainage. Ear Nose Throat J. 2020 Aug 03;:145561320942380 Authors: Nielsen CF, Riis CBS, Christensen ALB, Mirz F, Reinholdt KB, Ovesen T, Fjaeldstad AW Abstract BACKGROUND: Use of suction drain after superficial parotidectomy (SP) is based on national consensus considered best practice, but there is no evidence on the effect of the treatment. The aim of the present study is to evaluate...
Tue Aug 04, 2020 14:00
Auditory Cinchonism in COVID Era. Ear Nose Throat J. 2020 Aug 03;:145561320947255 Authors: Saniasiaya J, Kulasegarah J PMID: 32744901 [PubMed - as supplied by publisher]
Tue Aug 04, 2020 14:00
Inverted Papilloma of the Epiglottis: A Rare Case. Ear Nose Throat J. 2020 Aug 03;:145561320945567 Authors: Eo TS, Kim EK, Kim JH, Shin HA PMID: 32744900 [PubMed - as supplied by publisher]
Tue Aug 04, 2020 14:00
PSIGAN: Joint probabilistic segmentation and image distribution matching for unpaired cross-modality adaptation based MRI segmentation. IEEE Trans Med Imaging. 2020 Jul 23;PP: Authors: Jiang J, Hu YC, Tyagi N, Rimner A, Lee N, Deasy JO, Berry S, Veeraraghavan H Abstract We developed a new joint probabilistic segmentation and image distribution matching generative adversarial network (PSIGAN) for unsupervised domain adaptation (UDA) and...
Tue Aug 04, 2020 13:26
RUVBL1 is an amplified epigenetic factor promoting proliferation and inhibiting differentiation program in head and neck squamous cancers. Oral Oncol. 2020 Jul 31;111:104930 Authors: Lin D, Lin B, Bhanot H, Riou R, Abt NB, Rajagopal J, Saladi SV Abstract Mutations in histone modifying enzymes and histone variants were identified in multiple cancers in The Cancer Genome Atlas (TCGA) studies. However, very little progress and understanding...
Tue Aug 04, 2020 13:26
Head and neck robotic surgery combined with sentinel lymph node biopsy. Fascinating, but feasible? Oral Oncol. 2020 Jul 31;111:104939 Authors: Accorona R, D'Onghia A, Pignataro L, Capaccio P Abstract Robotic approaches and sentinel lymph node (SLN) biopsy are both strategies that evolved driven by the need to reduce impact of head and neck oncological surgery in terms of operative timing, morbidity, hospitalization time, and aesthetic...
Tue Aug 04, 2020 13:26
Grades of hearing loss affect the presence of acoustically evoked short latency negative responses in children with large vestibular aqueduct syndrome. Int J Pediatr Otorhinolaryngol. 2020 Jun 03;138:110159 Authors: Chen J, Chen Y, Zhang Q, Ma X, Mei L, Wang W, Shen J, Zhang Q, Wang L, Shen M, He K, Chen X, Yang J Abstract OBJECTIVES: We aimed to investigate the relationship between grades of hearing loss and the presence of acoustically...
Tue Aug 04, 2020 13:26
Utility of polysomnography and video swallow studies in the management of pediatric patients with congenital idiopathic bilateral vocal fold dysfunction. Int J Pediatr Otorhinolaryngol. 2020 Jul 25;138:110273 Authors: Ruda J, Pinto S, Allarakhia Z Abstract OBJECTIVES: Congenital idiopathic bilateral vocal fold dysfunction (BVFD) is an uncommon cause of neonatal stridor and respiratory distress postnatally. Approximately 50% of affected...
Tue Aug 04, 2020 13:26
Generation of two induced pluripotent stem cell lines from PBMCs of siblings carrying c.235delC mutation in the GJB2 gene associated with sensorineural hearing loss. Stem Cell Res. 2020 Jul 19;47:101910 Authors: Fukunaga I, Shirai K, Oe Y, Danzaki K, Ohta S, Shiga T, Chen C, Ikeda K, Akamatsu W, Kawano A, Kamiya K Abstract The gap junction beta-2 (GJB2) gene is the most common genetic cause of hereditary deafness worldwide. Especially,...
Tue Aug 04, 2020 13:26
Bicoronal Incision and Frontal-Basal Approach for Removal of Sinonasal Fibrous Dysplasia Complicated by Orbital Subperiosteal Abscess. World Neurosurg. 2020 Jul 31;: Authors: Hu CY, Wu CT, Chen CC, Fu CH Abstract BACKGROUND: Fibrous dysplasia(FD) is a benign, slowly progressive disease resulting from the replacement of normal bone by fibro-osseous tissue. The incidence of craniofacial involvement of FD is as high as 23%. Sinonasal involvement...
Tue Aug 04, 2020 13:26
Somatostatin receptor targeted radioligand therapy in head and neck paraganglioma. World Neurosurg. 2020 Jul 31;: Authors: Roll W, Müther M, Sporns PB, Zinnhardt B, Molina ES, Seifert R, Schäfers M, Weckesser M, Stegger L, Beule AG, Stummer W, Rahbar K Abstract OBJECTIVE: Surgical resection is the therapy of choice in head and neck paraganglioma (HNPGL), however associated with considerable morbidity. For treatment of inoperability or...
Tue Aug 04, 2020 13:26
Neutrophils: Accomplices in metastasis. Cancer Lett. 2020 Jul 31;: Authors: Zhu K, Li P, Mo Y, Wang J, Jiang X, Ge J, Huang W, Liu Y, Tang Y, Gong Z, Liao Q, Li X, Li G, Xiong W, Zeng Z, Yu J Abstract Metastasis is a critical cause of treatment failure and death in patients with advanced malignancies. Tumor cells can leave the primary site and enter the bloodstream; these circulating tumor cells then colonize target organs by overcoming...
Tue Aug 04, 2020 13:26
The Early Effects of Coronavirus Disease-2019 on Head and Neck Oncology and Microvascular Reconstruction Practice: A National Survey of Oral and Maxillofacial Surgeons Enrolled in the Head and Neck Special Interest Group. J Oral Maxillofac Surg. 2020 Jul 17;: Authors: Zaid W, Schlieve T Abstract PURPOSE: The coronavirus disease-2019 (COVID-19) pandemic has affected healthcare systems across the nation. The purpose of this study is to gauge...
Tue Aug 04, 2020 13:26
An Intravagal Parathyroid Adenoma in the Poststyloid Parapharyngeal Space. Laryngoscope. 2020 Aug 03;: Authors: Shonka DC, Danan D Abstract OBJECTIVES: Describe a case of an intravagal parathyroid adenoma. CASE: A 35-year-old male presented with symptomatic primary hyperparathyroidism and non-localizing imaging studies. Intraoperative venous sampling revealed a substantial gradient within the right internal jugular vein. Repeat...
Tue Aug 04, 2020 13:26
Endoscopic Muscle Repair of Right Internal Carotid Artery Rupture Following Endovascular Procedure. Laryngoscope. 2020 Aug 03;: Authors: Pathak S, Spock T, Gray M, Liu K, Shrivastava R, Iloreta A Abstract Carotid artery blowout syndrome (CBS) is a deadly complication usually linked to head and neck cancer therapy. We present a different etiology of endoscopic CBS, a complication of endovascular coiling of an intracranial aneurysm, treated...
Tue Aug 04, 2020 13:26
Molecular Profiling of Thyroid Nodules-Are These Findings Meaningful, or Merely Measurable?: A Review. JAMA Otolaryngol Head Neck Surg. 2020 Jul 30;: Authors: Morris LGT Abstract Importance: Advances in genomic technologies have facilitated the development of sophisticated molecular diagnostic tests for thyroid nodules, in the hopes of better risk stratifying nodules with indeterminate cytopathologic diagnosis. It is unclear whether the...
Tue Aug 04, 2020 13:26
Assessment of Gender Differences in Clinical Productivity and Medicare Payments Among Otolaryngologists in 2017. JAMA Otolaryngol Head Neck Surg. 2020 Jul 30;: Authors: Miller AL, Rathi VK, Burks CA, DeVore EK, Bergmark RW, Gray ST Abstract Importance: Women comprise an increasing proportion of the otolaryngology workforce. Prior studies have demonstrated gender-based disparity in physician practice and income in other clinical specialties;...
Tue Aug 04, 2020 13:26
Risk of SARS-CoV-2 Transmission During Flexible Laryngoscopy: A Systematic Review. JAMA Otolaryngol Head Neck Surg. 2020 Jul 30;: Authors: Kay JK, Parsel SM, Marsh JJ, McWhorter AJ, Friedlander PL Abstract Importance: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reportedly infected otolaryngologists disproportionately in the early parts of the coronavirus disease 2019 pandemic. Recommendations from national and international...
Tue Aug 04, 2020 13:26
Related Articles Elevation of Medial Sural Artery Perforator free flap in a chronically ischaemic donor leg: findings and outcome in a case of salvage laryngopharyngectomy. Microsurgery. 2020 Aug 03;: Authors: Edmondson SJ, Townley WA, Orfaniotis G PMID: 32744778 [PubMed - as supplied by publisher]
Tue Aug 04, 2020 13:26
Related Articles Clinical significance of tumor mutation burden and DNA damage repair in advanced stage non-small cell lung cancer patients. Eur Rev Med Pharmacol Sci. 2020 Jul;24(14):7664-7672 Authors: Zhang H, Deng YM, Chen ZC, Tang YC, Yang S, Zhang SD, Liang JM, Wang YG, Wu X, Zhang RW, Feng WN Abstract OBJECTIVE: This study aimed to investigate the impact of tumor mutational burden (TMB) and DNA damage repair (DDR) gene alteration...
Tue Aug 04, 2020 13:26
Related Articles Long noncoding RNA UCA1 promotes proliferation and metastasis of thyroid cancer cells by sponging miR-497-3p. Eur Rev Med Pharmacol Sci. 2020 Jul;24(14):7555 Authors: Gao H, Yang JY, Tong LX, Jin H, Liu CZ Abstract Since this article has been suspected of research misconduct and the corresponding authors did not respond to our request to prove originality of data and figures, "Long noncoding RNA UCA1 promotes proliferation...
Tue Aug 04, 2020 13:26
Related Articles Managing complications of endoscopic transsphenoidal surgery in pituitary adenomas. Expert Rev Endocrinol Metab. 2020 Aug 01;:1-9 Authors: Abhinav K, Tyler M, Dale OT, Mohyeldin A, Fernandez-Miranda JC, Katznelson L Abstract INTRODUCTION: Over the last two decades there has been a gradual shift from the traditional microscopic approach toward the use of endoscopic endonasal approach for resection of pituitary adenomas....
Tue Aug 04, 2020 13:26
Related Articles Acute Peripheral Facial Palsy: Recent Guidelines and a Systematic Review of the Literature. J Korean Med Sci. 2020 Aug 03;35(30):e245 Authors: Kim SJ, Lee HY Abstract BACKGROUND: This study reviews recent literature on facial palsy guidelines and provides systematic reviews on related topics of interest. METHODS: An electronic database search was performed to identify recent guidelines dealing with facial nerve...
Tue Aug 04, 2020 13:26
Related Articles Hearing loss and microstructural integrity of the brain in a dementia-free older population. Alzheimers Dement. 2020 Aug 02;: Authors: Croll PH, Vernooij MW, Reid RI, Goedegebure A, Power MC, Rigters SC, Sharrett AR, de Jong RJB, Mosley TH, de Groot M, Lin FR, Deal JA Abstract INTRODUCTION: As hearing loss has been identified as an important risk factor for dementia, we aimed to assess the association between hearing loss...
Tue Aug 04, 2020 13:26
Related Articles Cytotoxicity of dental disclosing solution on gingival epithelial cells in vitro. Clin Exp Dent Res. 2020 Aug 02;: Authors: Jung IH, Yeon KH, Song HR, Hwang YS Abstract OBJECTIVE: Coloring dental biofilm and plaque with a dental disclosing solution is visually effective in dental treatment and oral hygiene education. Despite continuous reports of the risk of the product ingredients, dental disclosing solution are widely...
Tue Aug 04, 2020 13:26
Related Articles The epidemiology, surgical management, and impact of margins in skull and mandibular osseous-site tumors. Head Neck. 2020 Aug 02;: Authors: Torabi SJ, Bourdillon A, Salehi PP, Kafle S, Mehra S, Rahmati R, Judson BL Abstract OBJECTIVE: Tha aim of the study was to characterize the epidemiology and treatment outcomes of head and neck (HN) osseous-site tumors. METHODS: Descriptive analyses and multivariate Cox regressions...
Tue Aug 04, 2020 13:26
Related Articles Association Among Age-Related Tongue Muscle Abnormality, Tongue Pressure, and Presbyphagia: A 3D MRI Study. Dysphagia. 2020 Aug 02;: Authors: Nakao Y, Yamashita T, Honda K, Katsuura T, Hama Y, Nakamura Y, Ando K, Ishikura R, Kodama N, Uchiyama Y, Domen K Abstract Muscle aging such as sarcopenia adversely affects motor activities. However, few studies have elucidated the aging physiological mechanism of tongue concerted...
Tue Aug 04, 2020 13:26
Related Articles Genetic Polymorphism of Head and Neck Cancers in African Populations: A Systematic Review. OTO Open. 2020 Jul-Sep;4(3):2473974X20942202 Authors: Okoturo E, Osasuyi A, Opaleye T Abstract Objective: Head and neck cancers are mostly composed of head and neck squamous cell carcinoma (HNSCC). The incidence and mortality of HNSCC are higher in countries with emerging health care systems, particularly Africa. Given that they are...
Tue Aug 04, 2020 13:26
Related Articles Eyelid Eccrine Poroma: A Case Report and Review of Literature. Cureus. 2020 Jun 29;12(6):e8906 Authors: Mencía-Gutiérrez E, Navarro-Perea C, Gutiérrez-Díaz E, Cámara-Jurado M, Bengoa-González Á Abstract Poroma is a rare benign tumor of the epidermal sweat duct unit with predilection for the head and neck. Only six cases with eyelid location have been described in the literature (PubMed). A 34-year-old male presented with...
Tue Aug 04, 2020 13:26
Related Articles Eosinophilic airway inflammation and eosinophilic chronic rhinosinusitis during nivolumab and ipilimumab. Respirol Case Rep. 2020 Oct;8(7):e00638 Authors: Watanabe H, Asada K, Shirai T, Torii H, Yoshimura K, Kusafuka K Abstract Immune-related adverse events (irAEs) are induced by immune checkpoint inhibitors (ICIs) which are administered for many cancers. There are many irAEs such as endocrine abnormalities, interstitial...
Tue Aug 04, 2020 13:26
Related Articles Allergen exposure chambers: implementation in clinical trials in allergen immunotherapy. Clin Transl Allergy. 2020;10:33 Authors: Pfaar O, Zieglmayer P Abstract Allergen exposure chambers (AECs) have been developed for controlled allergen challenges of allergic patients mimicking natural exposure. As such, these facilities have been utilized e.g., for proof of concept, dose finding or the demonstration of onset of action...
Tue Aug 04, 2020 13:26
Related Articles Serum Exosomal miR-941 as a promising Oncogenic Biomarker for Laryngeal Squamous Cell Carcinoma. J Cancer. 2020;11(18):5329-5344 Authors: Zhao Q, Zheng X, Guo H, Xue X, Zhang Y, Niu M, Cui J, Liu H, Luo H, Yang D, Shi Y, Huangfu H, Wen S, Wu Y, Gao W, Wang B Abstract At present, no blood-based biomarkers have been used in clinical practice for laryngeal squamous cell carcinoma (LSCC). Increasing evidence suggests that circulating...
Tue Aug 04, 2020 13:26
Related Articles Prognostic values of m6A RNA methylation regulators in differentiated Thyroid Carcinoma. J Cancer. 2020;11(17):5187-5197 Authors: Xu N, Chen J, He G, Gao L, Zhang D Abstract N6-methyladenosine (m6A) is the most prevalent modification of RNA in mammals. m6A RNA methylation levels are dynamically regulated by m6A RNA methylation regulators. While increasing evidence has suggested that m6A RNA methylation is vital in the initiation...
Tue Aug 04, 2020 13:26
Related Articles The correlation and role analysis of KCNK2/4/5/15 in Human Papillary Thyroid Carcinoma microenvironment. J Cancer. 2020;11(17):5162-5176 Authors: Lin X, Wu JF, Wang DM, Zhang J, Zhang WJ, Xue G Abstract Background: KCNKs, potassium two pore domain channel family K members, can maintain the resting potential, regulate the amplitude and duration of the plateau of the action potential, and change the membrane potential and...
Tue Aug 04, 2020 13:26
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