Web-based Didactics in the Era of COVID-19 and Beyond. World Neurosurg. 2020 Jul 31;: Authors: Aljuboori Z PMID: 32745651 [PubMed - as supplied by publisher]
Tue Aug 04, 2020 13:26
Analysis of the causes and experience in the diagnosis and treatment of intravertebral mobile nerve sheath tumors------a case report and review of the literature. World Neurosurg. 2020 Jul 31;: Authors: You W, Hu W, Wang F, Pan Z, Zhu Q, Zhou J, Hu W Abstract OBJECTIVE: To analyze the clinical data and imaging features from a rare case presenting intravertebral mobile nerve sheath tumor of the lumbar spine, review the relevant literature, discuss...
Tue Aug 04, 2020 13:26
Spinal metastasis of cerebral Glioblastoma (GBM) with genetic profile: case report and review of literature. World Neurosurg. 2020 Jul 31;: Authors: Shaaban A, Rajeswaran A, Elbadry RG, Haddad R, Al-Bozom I, Ayyad A, Belkhair S Abstract Spinal metastasis of cerebral glioblastoma (GBM) is very rare, with some reports suggesting a prevalence of 1-2%. (1) Herein, we present 2 unique cases of spinal metastasis of cerebral GBM, one of which was...
Tue Aug 04, 2020 13:26
Neurologic Clinical Manifestations of Fahr's Syndrome and Hypoparathyroidism. World Neurosurg. 2020 Jul 31;: Authors: Kwasnicki A, McGuire LS, Lichtenbaum R Abstract A 41-year-old female with a history of chronic hypoparathyroidism with Fahr's syndrome presented with complaints of weakness and muscle spasticity. Brain imaging demonstrated diffuse intracranial calcifications. In addition, cervical spine imaging revealed extensive calcification...
Tue Aug 04, 2020 13:26
Bicoronal Incision and Frontal-Basal Approach for Removal of Sinonasal Fibrous Dysplasia Complicated by Orbital Subperiosteal Abscess. World Neurosurg. 2020 Jul 31;: Authors: Hu CY, Wu CT, Chen CC, Fu CH Abstract BACKGROUND: Fibrous dysplasia(FD) is a benign, slowly progressive disease resulting from the replacement of normal bone by fibro-osseous tissue. The incidence of craniofacial involvement of FD is as high as 23%. Sinonasal involvement...
Tue Aug 04, 2020 13:26
Spontaneous Regression Followed by Rupture of an Untreated Brain Arteriovenous Malformation. World Neurosurg. 2020 Jul 31;: Authors: Joud H, Peto I, Noureldine MHA, Mokin M, Agazzi S Abstract BACKGROUND: Brain arteriovenous malformations (AVMs) are dynamic lesions. Unlike the recruitment of additional vessels and the growth of the nidus over time that are well reported in the literature, spontaneous regression is much less frequent. Only a...
Tue Aug 04, 2020 13:26
A Surprise Sabbatical: How Mayo Clinic Neurosurgery Coped with COVID-19. World Neurosurg. 2020 Jul 31;: Authors: Graffeo CS, Parney IA, Wessel B, Spinner RJ PMID: 32745645 [PubMed - as supplied by publisher]
Tue Aug 04, 2020 13:26
Microvascular Decompression Versus Stereotactic Radiosurgery for Trigeminal Neuralgia: A single institution experience. World Neurosurg. 2020 Jul 31;: Authors: Li L, Seaman SC, Bathla G, Smith MC, Dundar B, Noeller J, Hitchon PW PMID: 32745644 [PubMed - as supplied by publisher]
Tue Aug 04, 2020 13:26
Clinical Impact of Hematoma Expansion in Left Ventricular Assist Device Patients. World Neurosurg. 2020 Jul 31;: Authors: Melmed KR, Mondellini G, Roh D, Boehme A, Park S, Yuzefpolskya M, Naka Y, Uriel N, Agarwal S, Connolly ES, Claassen J, Colombo PC, Willey JZ Abstract INTRODUCTION: Hematoma expansion (HE) is associated with poor outcome in intracerebral hemorrhage (ICH) patients, but the impact on left ventricular assist device (LVAD) patients...
Tue Aug 04, 2020 13:26
Somatostatin receptor targeted radioligand therapy in head and neck paraganglioma. World Neurosurg. 2020 Jul 31;: Authors: Roll W, Müther M, Sporns PB, Zinnhardt B, Molina ES, Seifert R, Schäfers M, Weckesser M, Stegger L, Beule AG, Stummer W, Rahbar K Abstract OBJECTIVE: Surgical resection is the therapy of choice in head and neck paraganglioma (HNPGL), however associated with considerable morbidity. For treatment of inoperability or progressive...
Tue Aug 04, 2020 13:26
Related Articles Letter to the Editor: COVID-19 and the Neurosurgical Treatment of Idiopathic Normal Pressure Hydrocephalus: Shall We Continue to Postpone "Non-emergent" Surgical Procedures? World Neurosurg. 2020 Jul 29;: Authors: La Corte E, Palandri G PMID: 32741739 [PubMed - as supplied by publisher]
Tue Aug 04, 2020 13:26
Related Articles Letter to the Editor: Spinal and Neurosurgical Publications During the COVID-19 Era. World Neurosurg. 2020 Jul 15;: Authors: Al-Saadi T, Al-Kalbani H, Lam J PMID: 32741738 [PubMed - as supplied by publisher]
Tue Aug 04, 2020 13:26
Related Articles Cellular Senescence: Mechanisms, Morphology, and Mouse Models. Vet Pathol. 2020 Aug 03;:300985820943841 Authors: Beck J, Horikawa I, Harris C Abstract Cellular senescence is a cell cycle arrest in damaged or aged cells. Although this represents a critical mechanism of tumor suppression, persistence of senescent cells during aging induces chronic inflammation and tissue dysfunction through the adoption of the senescence-associated...
Tue Aug 04, 2020 13:25
Related Articles [Effects of α-enolase gene interference expression on proliferation and apoptosis of follicular granulosa cells from Zi geese]. Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2020 Mar;36(2):184-188 Authors: Ji H, Shao ZY, Xue LL, Niu CY, Zhan XL, Yang C, Zhen L, Yang HM, Li SZ Abstract Objective: To study the effects of α-enolase (ENO1) gene interference expression on proliferation, and cell cycle of follicular granulosa cells...
Tue Aug 04, 2020 13:25
Related Articles HOTAIR promotes paclitaxel resistance by regulating CHEK1 in ovarian cancer. Cancer Chemother Pharmacol. 2020 Aug 02;: Authors: Jiang J, Wang S, Wang Z, Cai J, Han L, Xie L, Han Q, Wang W, Zhang Y, He X, Yang C Abstract PURPOSE: The HOX transcript antisense RNA (HOTAIR) has been reported to be aberrantly expressed in ovarian cancer (OC). Abnormal high expression level of HOTAIR has been found to be associated with poor...
Tue Aug 04, 2020 13:25
Related Articles Role for Metallothionein-3 in the Resistance of Human U87 Glioblastoma Cells to Temozolomide. ACS Omega. 2020 Jul 28;5(29):17900-17907 Authors: Santangelo R, Rizzarelli E, Copani A Abstract Metallothioneins (MTs) are metal-binding proteins that are overexpressed in various human cancers and are thought to be associated with resistance to cytotoxic drugs. The knowledge on MT expression, regulation, and function in human...
Tue Aug 04, 2020 13:25
Related Articles ASIC1a Inhibitor mambalgin-2 Suppresses the Growth of Leukemia Cells by Cell Cycle Arrest. Acta Naturae. 2020 Apr-Jun;12(2):101-116 Authors: Bychkov ML, Shulepko MA, Vasileva VY, Sudarikova AV, Kirpichnikov MP, Lyukmanova EN Abstract Although tyrosine kinase inhibitors have brought significant success in the treatment of chronic myelogenous leukemia, the search for novel molecular targets for the treatment of this disease...
Tue Aug 04, 2020 13:25
Related Articles DGCR5 Promotes Gallbladder Cancer by Sponging MiR-3619-5p via MEK/ERK1/2 and JNK/p38 MAPK Pathways. J Cancer. 2020;11(18):5466-5477 Authors: Liu S, Chu B, Cai C, Wu X, Yao W, Wu Z, Yang Z, Li F, Liu Y, Dong P, Gong W Abstract Gallbladder cancer (GBC) is a highly aggressive malignant cancer with poor prognosis. Long noncoding RNA (lncRNA) DiGeorge syndrome critical region gene (DGCR5) has been reported to participate in...
Tue Aug 04, 2020 13:25
Related Articles MST4 inhibits human hepatocellular carcinoma cell proliferation and induces cell cycle arrest via suppression of PI3K/AKT pathway. J Cancer. 2020;11(17):5106-5117 Authors: Hao WC, Zhong QL, Pang WQ, Dian MJ, Li J, Han LX, Zhao WT, Zhang XL, Xiao SJ, Xiao D, Lin XL, Jia JS Abstract Objective: MST4 has exhibited functions in regulating cell polarity, Golgi apparatus, cell migration, and cancer. Mechanistically, it affects...
Tue Aug 04, 2020 13:25
Related Articles Anti-tumor peptide SA12 inhibits metastasis of MDA-MB-231 and MCF-7 breast cancer cells via increasing expression of the tumor metastasis suppressor genes, CDH1, nm23-H1 and BRMS1. Exp Ther Med. 2020 Aug;20(2):1758-1763 Authors: Yang L, Lin F, Gao Z, Chen X, Zhang H, Dong K Abstract In recent years, there has been progress in the treatment of breast cancer; however, the prognosis is still poor due to recurrence and metastasis...
Tue Aug 04, 2020 13:25
Related Articles CacyBP/SIP promotes tumor progression by regulating apoptosis and arresting the cell cycle in osteosarcoma. Exp Ther Med. 2020 Aug;20(2):1397-1404 Authors: Zhao M, Zhang RZ, Qi DW, Chen HY, Zhang GC Abstract Osteosarcoma (OS) is the most common primary malignant bone tumor in pediatric and adolescent patients. The calcyclin-binding protein/Siah-1-interacting protein (CacyBP/SIP) performs an essential function in cell proliferation...
Tue Aug 04, 2020 13:25
Circ_0000190 suppresses gastric cancer progression potentially via inhibiting miR-1252/PAK3 pathway.
Related Articles Circ_0000190 suppresses gastric cancer progression potentially via inhibiting miR-1252/PAK3 pathway. Cancer Cell Int. 2020;20:351 Authors: Wang GJ, Yu TY, Li YR, Liu YJ, Deng BB Abstract Background: Gastric cancer is a serious malignant tumor associated with aberrant circular RNAs (circRNAs) expression. In this study, we aim to investigate the role and the underlying mechanism of circ_0000190, a circRNA in gastric cancer....
Tue Aug 04, 2020 13:25
Related Articles TBL1XR1 induces cell proliferation and inhibit cell apoptosis by the PI3K/AKT pathway in pancreatic ductal adenocarcinoma. World J Gastroenterol. 2020 Jul 07;26(25):3586-3602 Authors: Gu JF, Fu W, Qian HX, Gu WX, Zong Y, Chen Q, Lu L Abstract BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest solid tumors. Identification of diagnostic and therapeutic biomarkers for PDAC is urgently needed. Transducin...
Tue Aug 04, 2020 13:25
Related Articles Retinoic Acid-Platinum (II) Complex [RT-Pt(II)] Protects Against Rheumatoid Arthritis in Mice via MEK/Nuclear Factor kappa B (NF-κB) Pathway Downregulation. Med Sci Monit. 2020 Aug 03;26:e924787 Authors: Cui Z, Lin Y, Liu Y, Cao L, Cui L Abstract BACKGROUND Rheumatoid arthritis (RA) is an inflammatory disorder that is present in approximately 1% of the world's population. This study was aimed to investigate the effect of...
Tue Aug 04, 2020 13:25
Related Articles In Barrett's epithelial cells, weakly acidic bile salt solutions cause oxidative DNA damage with response and repair mediated by p38. Am J Physiol Gastrointest Liver Physiol. 2020 03 01;318(3):G464-G478 Authors: Huo X, Dunbar KB, Zhang X, Zhang Q, Spechler SJ, Souza RF Abstract The frequency of esophageal adenocarcinoma is rising despite widespread use of proton pump inhibitors (PPIs), which heal reflux esophagitis but do not...
Tue Aug 04, 2020 13:25
Related Articles Discovery and Optimization of Small Molecules Targeting the Protein-Protein Interaction of Heat Shock Protein 90 (Hsp90) and Cell Division Cycle 37 as Orally Active Inhibitors for the Treatment of Colorectal Cancer. J Med Chem. 2020 02 13;63(3):1281-1297 Authors: Wang L, Jiang J, Zhang L, Zhang Q, Zhou J, Li L, Xu X, You Q Abstract Cell division cycle 37 (Cdc37) is known to work as a kinase-specific cochaperone, which selectively...
Tue Aug 04, 2020 13:25
Related Articles WIP1 Promotes Homologous Recombination and Modulates Sensitivity to PARP Inhibitors. Cells. 2019 10 15;8(10): Authors: Burdova K, Storchova R, Palek M, Macurek L Abstract Genotoxic stress triggers a combined action of DNA repair and cell cycle checkpoint pathways. Protein phosphatase 2C delta (referred to as WIP1) is involved in timely inactivation of DNA damage response by suppressing function of p53 and other targets at chromatin....
Tue Aug 04, 2020 13:25
Related Articles Combination of ERK2 inhibitor VX-11e and voreloxin synergistically enhances anti-proliferative and pro-apoptotic effects in leukemia cells. Apoptosis. 2019 12;24(11-12):849-861 Authors: Jasek-Gajda E, Jurkowska H, Jasińska M, Litwin JA, Lis GJ Abstract ERK1/2 inhibitors are new promising anticancer drugs. The aim of this study was to investigate the effect of the combination of ERK2 inhibitor VX-11e and voreloxin on MOLM-14,...
Tue Aug 04, 2020 13:25
Related Articles Long noncoding RNA LINC02418 regulates MELK expression by acting as a ceRNA and may serve as a diagnostic marker for colorectal cancer. Cell Death Dis. 2019 07 29;10(8):568 Authors: Zhao Y, Du T, Du L, Li P, Li J, Duan W, Wang Y, Wang C Abstract Some types of long noncoding RNAs (lncRNAs) are aberrantly expressed in human diseases, including cancer. However, the overall biological roles and clinical significances of most lncRNAs...
Tue Aug 04, 2020 13:25
Related Articles Cordycepin-induced unfolded protein response-dependent cell death, and AKT/MAPK-mediated drug resistance in mouse testicular tumor cells. Cancer Med. 2019 07;8(8):3949-3964 Authors: Chang MM, Pan BS, Wang CY, Huang BM Abstract Testicular cancer is the most commonly diagnosed cancer in men at 15-44 years of age, and radical orchidectomy combined with chemotherapy is currently considered as the standard treatment. However, drugs...
Tue Aug 04, 2020 13:25
Related Articles Overexpression of PRDM5 promotes acute myeloid leukemia cell proliferation and migration by activating the JNK pathway. Cancer Med. 2019 07;8(8):3905-3917 Authors: Zhou P, Chen X, Li M, Sun X, Tan J, Wang X, Chu Y, Zhang Y, Cheng T, Zhou J, Wang G, Yuan W Abstract PRDM family proteins are dysregulated in many human diseases, especially hematological malignancies and solid cancers, and share a unique N-terminal PR domain followed...
Tue Aug 04, 2020 13:25
Related Articles Down-regulation of CCNE1 expression suppresses cell proliferation and sensitizes gastric carcinoma cells to Cisplatin. Biosci Rep. 2019 06 28;39(6): Authors: Zhang C, Zhu Q, Gu J, Chen S, Li Q, Ying L Abstract A novel oncogene CCNE1 (cyclin E) is considered to be associated with the development of various tumor types, its role in gastric carcinoma (GC) is little studied and the effect of CCNE1 on chemotherapy also remains...
Tue Aug 04, 2020 13:25
26 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: epilepsy treatment These pubmed results were generated on 2020/08/04PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Tue Aug 04, 2020 14:34
Electric Stimulation of Neurogenesis Improves Behavioral Recovery After Focal Ischemia in Aged Rats.
Related Articles Electric Stimulation of Neurogenesis Improves Behavioral Recovery After Focal Ischemia in Aged Rats. Front Neurosci. 2020;14:732 Authors: Balseanu AT, Grigore M, Pinosanu LR, Slevin M, Hermann DM, Glavan D, Popa-Wagner A Abstract The major aim of stroke therapies is to stimulate brain repair and to improve behavioral recuperation after cerebral ischemia. Despite remarkable advances in cell therapy for stroke, stem cell-based...
Tue Aug 04, 2020 13:14
Related Articles Functional Near-Infrared Spectroscopy and Its Clinical Application in the Field of Neuroscience: Advances and Future Directions. Front Neurosci. 2020;14:724 Authors: Chen WL, Wagner J, Heugel N, Sugar J, Lee YW, Conant L, Malloy M, Heffernan J, Quirk B, Zinos A, Beardsley SA, Prost R, Whelan HT Abstract Similar to functional magnetic resonance imaging (fMRI), functional near-infrared spectroscopy (fNIRS) detects the changes...
Tue Aug 04, 2020 13:14
Related Articles Neuroprotection Against Parkinson's Disease Through the Activation of Akt/GSK3β Signaling Pathway by Tovophyllin A. Front Neurosci. 2020;14:723 Authors: Huang Y, Sun L, Zhu S, Xu L, Liu S, Yuan C, Guo Y, Wang X Abstract Parkinson's disease (PD) is one of the most prevalent and life-threatening neurodegenerative disease and mainly characterized by lack of sufficient dopaminergic neurons in the substantia nigra pars compacta (SNc)....
Tue Aug 04, 2020 13:14
Related Articles Discovery of a Role for Rab3b in Habituation and Cocaine Induced Locomotor Activation in Mice Using Heterogeneous Functional Genomic Analysis. Front Neurosci. 2020;14:721 Authors: Bubier JA, Philip VM, Dickson PE, Mittleman G, Chesler EJ Abstract Substance use disorders are prevalent and present a tremendous societal cost but the mechanisms underlying addiction behavior are poorly understood and few biological treatments exist....
Tue Aug 04, 2020 13:14
Related Articles Functional Electrical Stimulation Therapy for Retraining Reaching and Grasping After Spinal Cord Injury and Stroke. Front Neurosci. 2020;14:718 Authors: Kapadia N, Moineau B, Popovic MR Abstract Neurological conditions like hemiplegia following stroke or tetraplegia following spinal cord injury, result in a massive compromise in motor function. Each of the two conditions can leave individuals dependent on caregivers for the...
Tue Aug 04, 2020 13:14
Related Articles Differential Atrophy in the Hippocampal Subfield Volumes in Four Types of Mild Dementia. Front Neurosci. 2020;14:699 Authors: Huang L, Chen K, Hu X, Guo Q Abstract Objectives: To investigate the bilateral hippocampal subfield volumetric differences in four types of mild dementia, namely typical Alzheimer's disease (tAD), dementia with Lewy bodies (DLB), semantic dementia (SD), and posterior cortical atrophy (PCA), to assist...
Tue Aug 04, 2020 13:14
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