Related Articles Sensorineural hearing loss and hypoplastic cochlea in Axenfeld-Rieger syndrome with FOXC1 mutation. Auris Nasus Larynx. 2020 Jul 30;: Authors: Yamazaki H, Nakamura T, Hosono K, Yamaguchi T, Hiratsuka Y, Hotta Y, Takahashi M Abstract OBJECTIVE: Axenfeld-Rieger syndrome (ARS) type 3 is a rare autosomal dominant disease, characterized by anterior segment dysgenesis of the eye, hearing loss, and cardiac defects. ARS type 3 is highly...
Related Articles How goblet cells respond to dry eye: adaptive and pathological roles of voltage-gated calcium channels and P2X7 purinoceptors. Am J Physiol Cell Physiol. 2020 06 01;318(6):C1305-C1315 Authors: Puro DG Abstract Dry eye is a common sight-impairing, painful disorder characterized by disruption of the preocular tear film, whose integrity is required for ~70% of the eye's refractive power. A universal feature of clinical dry eye...
Related Articles [Atypical laryngeal carcinoid: a case report]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 04 07;55(4):408-410 Authors: Luo B, Xie MQ, Guo JF PMID: 32306643 [PubMed - indexed for MEDLINE]
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Related Articles Local inflammatory reaction to benign, pre-malignant and malignant glottic lesions: A matched case-control study. Clin Otolaryngol. 2019 07;44(4):628-638 Authors: Lahav Y, Shats M, Huszar M, Haimovich Y, Warman M, Halperin D, Shoffel-Havakuk H Abstract OBJECTIVES: To study the inflammatory infiltrates associated with the different stages of laryngeal carcinogenesis. DESIGN: Observational, matched case-control study...
Related Articles Does early glottic cancer recur early? A retrospective study of recurrence and mortality in 61 patients with T1 and T2 glottic cancers. Clin Otolaryngol. 2019 07;44(4):677-681 Authors: Liu A, Bowles P, Walker D, Harries M PMID: 31009152 [PubMed - indexed for MEDLINE]
Related Articles Vocal nodules management. Clin Otolaryngol. 2019 07;44(4):497-501 Authors: Birchall MA, Carding P Abstract Vocal fold nodules present the voice clinic team with a number of clinical dilemmas which are not as simple as previously thought. The definition, aetiology, prevalence and diagnosis are all poorly understood. Furthermore, treatment evidence for both behavioural and surgical approaches is weak. This paper reviews the published...
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Modulation of TASK-1/3 Channels at the Hypoglossal Motoneuron Pool and Effects on Tongue Motor Output and Responses to Excitatory Inputs In-Vivo: Implications for Strategies for Obstructive Sleep Apnea Pharmacotherapy. Sleep. 2020 Aug 03;: Authors: Gurges P, Liu H, Horner RL Abstract Obstructive sleep apnea (OSA) occurs exclusively during sleep due to reduced tongue motor activity. Withdrawal of excitatory inputs to the hypoglossal motor nucleus...
The Supraorbital Eyebrow Craniotomy for Intra- and Extra-Axial Brain Tumors: A Single-Center Series and Technique Modification. Oper Neurosurg (Hagerstown). 2020 Aug 03;: Authors: Ansari SF, Eisenberg A, Rodriguez A, Barkhoudarian G, Kelly DF Abstract BACKGROUND: The supraorbital (SO) eyebrow craniotomy provides minimally invasive access to the anterior and middle fossae and parasellar region. OBJECTIVE: To present a series of patients...
Related Articles Managing complications of endoscopic transsphenoidal surgery in pituitary adenomas. Expert Rev Endocrinol Metab. 2020 Aug 01;:1-9 Authors: Abhinav K, Tyler M, Dale OT, Mohyeldin A, Fernandez-Miranda JC, Katznelson L Abstract INTRODUCTION: Over the last two decades there has been a gradual shift from the traditional microscopic approach toward the use of endoscopic endonasal approach for resection of pituitary adenomas. Multiple...
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Related Articles COVID-19, rules of conduct for dental care in children during pandemic. Minerva Stomatol. 2020 Aug 03;: Authors: Ludovichetti FS, Signoriello AG, Stellini E, Mazzoleni S PMID: 32744445 [PubMed - as supplied by publisher]
Related Articles Recognition of lysyl oxidase as a potential predictive biomarker for oral squamous cell carcinoma: an immunohistochemical study. Minerva Stomatol. 2020 Aug 03;: Authors: Bhanu U, Natarajan S, Manaktala N, Boaz K, Joshi R, Deepak S, Kp N, Lewis AJ Abstract BACKGROUND: Lysyl Oxidase (LOX) is a copper amine oxidase which belongs to the LOX multigene family and is normally involved in cross-linking of stromal collagen fibres. LOX...
Related Articles Standardization of a cone beam computed tomography machine in evaluating bone density: a novel approach. Minerva Stomatol. 2020 Aug 03;: Authors: Chennoju SK, Ramaswamy P, Neelima V, Mrudula B, Swathi M Abstract BACKGROUND: Advent of Cone Beam Computed Tomography (CBCT) in dentistry has brought us to a new era of precise imaging. Radiographic evaluation of a CBCT image is more informational when compared to CT. The density measurements...
Related Articles Familiar occurrence of facial asymmetry: a pilot study. Minerva Stomatol. 2020 Aug 03;: Authors: Galluccio G, Caridi V, Impellizzeri A, Chudan AP, Vernucci R, Barbato E Abstract BACKGROUND: The point at which "normal" asymmetry becomes "abnormal" can be defined by an aesthetic limit and a functional limit. The underlying causes are still not fully discovered; the etiology includes congenital disorders, acquired diseases, and...
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Hypoferritinemia and iron deficiency in youth with pediatric acute-onset neuropsychiatric syndrome. Pediatr Res. 2020 Aug 03;: Authors: Chan A, Karpel H, Spartz E, Willett T, Farhadian B, Jeng M, Thienemann M, Frankovich J Abstract BACKGROUND: Pediatric acute-onset neuropsychiatric syndrome (PANS) is an abrupt debilitating psychiatric illness. We anecdotally observed hypoferritinemia and iron deficiency in a subset of patients with PANS, prompting...
Related Articles Cancer Testis Antigen Expression Across T-Cell Lymphoma Subtypes. Hematol Oncol. 2020 Aug 03;: Authors: Ma H, Soderquist CR, Marchi E, Scotto L, Bhagat G, O'Connor OA Abstract To better understand the expression of cancer testis antigens (CTA) and its association with clinical outcomes on patients with T-cell lymphomas, we sought to establish a baseline level of expression of CTA across a diversity of PTCL subtypes. Lymphoma...
Related Articles Italy, where a judge could decide the future of immunization policies. Ann Ig. 2020 Jul-Aug;32(4):430-432 Authors: Tafuri S, Stefanizzi P PMID: 32744301 [PubMed - in process]
Related Articles Affinity maturation of antibodies by combinatorial codon mutagenesis versus error-prone PCR. MAbs. 2020 Aug 02;:1803646 Authors: Simons JF, Lim YW, Carter KP, Wagner EK, Wayham N, Adler AS, Johnson DS Abstract IN VITRO: affinity maturation of therapeutic monoclonal antibodies is commonly applied to achieve desired properties, such as improved binding kinetics and affinity. Currently there are no universally accepted protocols...
Related Articles Salivary gland cancer in the era of immunotherapy: can we exploit tumor microenvironment? Expert Opin Ther Targets. 2020 Aug 01;: Authors: Theocharis S, Tasoulas J, Masaoutis C, Kokkali S, Klijanienko J Abstract INTRODUCTION: Salivary gland cancers (SGCs) consist a rare family of neoplasms with varying histology and biological behavior. Therapeutic regimens have been relatively unchanged for decades. The recent successes of...
Related Articles A meta-analysis and in silico analysis of polymorphic variants conferring breast cancer risk in the Indian subcontinent. Future Oncol. 2020 Aug 01;: Authors: Sengupta D, Banerjee S, Mukhopadhyay P, Guha U, Ganguly K, Bhattacharjee S, Sengupta M Abstract Background: Genetic association studies on breast cancer on the Indian subcontinent have yielded conflicting results, and the precise effect of these variants on breast cancer...
Related Articles Cancer stem cell plasticity in glioblastoma multiforme: a perspective on future directions in oncolytic virotherapy. Future Oncol. 2020 Aug 02;: Authors: Kim DS Abstract The cancer stem cell (CSC) hypothesis suggests that a rare population of stem-like cells underpin tumorigenesis. Oncolytic viruses (OVs) demonstrate novel mechanisms of targeting the elusive CSCs with greater selectivity - promising therapeutic potential against...
Related Articles Pattern of Relapse and Treatment Response in WNT-Activated Medulloblastoma. Cell Rep Med. 2020 Jun 23;1(3): Authors: Nobre L, Zapotocky M, Khan S, Fukuoka K, Fonseca A, McKeown T, Sumerauer D, Vicha A, Grajkowska WA, Trubicka J, Li KKW, Ng HK, Massimi L, Lee JY, Kim SK, Zelcer S, Vasiljevic A, Faure-Conter C, Hauser P, Lach B, van Veelen-Vincent ML, French PJ, Van Meir EG, Weiss WA, Gupta N, Pollack IF, Hamilton RL, Nageswara Rao AA, Giannini...
Related Articles Acute myelomonocytic leukemia during pembrolizumab treatment for non-small cell lung cancer: A case report. World J Clin Cases. 2020 Jul 06;8(13):2833-2840 Authors: Kim HB, Park SG, Hong R, Kang SH, Na YS Abstract BACKGROUND: Pembrolizumab is a highly selective IgG4 kappa isotype monoclonal antibody against the programmed cell death-1 (PD-1) molecule. In the treatment of non-small cell lung cancer (NSCLC), pembrolizumab has...
Related Articles Androgen receptor in bladder cancer: A promising therapeutic target. Asian J Urol. 2020 Jul;7(3):284-290 Authors: Tripathi A, Gupta S Abstract There has been a significant progress in the treatment of metastatic urothelial carcinoma in the last few years with the advent of immunotherapy after a long gap of no drug approvals for over 4 decades. While immunotherapy with checkpoint inhibitors has revolutionized the treatment of...
Related Articles Venetoclax in the Treatment of Chronic Lymphocytic Leukemia: Evidence, Expectations, and Future Prospects. Cureus. 2020 Jun 29;12(6):e8908 Authors: Tariq S, Tariq S, Khan M, Azhar A, Baig M Abstract Chronic lymphocytic leukemia (CLL) is the most common form of leukemia in the western adult population; it is also prevalent worldwide. The B cell lymphoma-2 (BCL-2) family proteins play a key role in regulating intrinsic apoptosis...
Related Articles Perspectives in the Rapidly Evolving Treatment Landscape of Multiple Myeloma: Expert Review of New Data Presentations from ASH 2019. Clin Lymphoma Myeloma Leuk. 2020 Jun 29;: Authors: Joo CW, Quach H, Raje N Abstract The number and type of therapeutic options available to treat patients with multiple myeloma has risen dramatically over recent years, offering exciting opportunities to significantly improve the future management...
Related Articles Clinical outcomes of childhood Langerhans cell histiocytosis in Taiwan: A single-center, 20-year experience. J Formos Med Assoc. 2020 Jul 30;: Authors: Wang DS, Lu MY, Yang YL, Lin DT, Lin KH, Chang HH, Jou ST Abstract BACKGROUND/PURPOSE: The Taiwan Pediatric Oncology Group (TPOG) initiated two consecutive protocols for treating pediatric patients with Langerhans cell histiocytosis (LCH) since 1994. However, the results have...
Related Articles A How-To Guide: Virtual Interviews in the Era of Social Distancing. J Surg Educ. 2020 Jul 30;: Authors: Hill MV, Bleicher RJ, Farma JM Abstract The coronavirus crisis hit at the beginning of the Complex General Surgical Oncology Fellowship (CGSO) and Breast Oncology Fellowship interview cycles. Within 2 weeks, nearly all programs, including ours, switched to a virtual platform for the remainder of the season. Given that social...
Related Articles Integrative Approaches for Sleep Health in Cancer Survivors. Cancer J. 2019 Sep/Oct;25(5):337-342 Authors: Garland SN, Mahon K, Irwin MR Abstract Sleep disturbance and insomnia are prevalent problems for the more than 15 million cancer survivors in the United States. If not addressed, poor-quality sleep can negatively impact physical and psychological recovery from cancer diagnosis and treatment. Cancer survivors are increasingly...
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Related Articles Taste Dysfunction after Tonsillectomy: A Meta-analysis. Ann Otol Rhinol Laryngol. 2020 Aug 01;:3489420946770 Authors: Kim BY, Lee SJ, Yun JH, Bae JH Abstract OBJECTIVES: We aimed to provide information on the effects of tonsillectomy, in particular, its effects on taste dysfunction; also known as dysgeusia, and provide direction for future research in this area. METHODS: We independently searched five databases...
Related Articles Bedside Surgical Tracheostomy in the Intensive Care Unit during Covid-19 Pandemic. Ann Otol Rhinol Laryngol. 2020 Aug 01;:3489420947767 Authors: Di Lella F, Picetti E, Ciavarro G, Pepe G, Malchiodi L, D'Angelo G, Grossi S, Rossi S, Falcioni M Abstract OBJECTIVES: To describe Otolaryngologists' perspective in managing COVID-19 patients with acute respiratory distress syndrome (ARDS) requiring tracheostomy in the ICUs during...
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Thymolipoma Association with Myasthenia Gravis: Case Report. Am J Case Rep. 2020 Aug 03;21:e923989 Authors: Othman SA, AlFrayyan OY, AlGhamdi ZM, Makhdom F, AlJehani Y, Elbawab HY, El-Shawarby M Abstract BACKGROUND Thymolipoma, which was described initially by Hall in 1949, is an uncommon benign thymic tumor that represents around 9% of all thymic tumors. The incidence of thymolipoma is around 0.12 out of 100 000 cases per year, with a higher...
Related Articles Acute Spontaneous Spinal Subdural Hematoma: A Case Report. Am J Case Rep. 2020 Aug 03;21:e922416 Authors: Mitwalli MY, Elmoheen A, Bashir K Abstract BACKGROUND Spontaneous spinal subdural hematoma is a rare condition that can lead to devastating neurologic deficits, usually caused by coagulation abnormalities, trauma, underlying neoplasm, or arteriovenous malformation. The patient presents with local and/or radicular pain, followed...
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Related Articles Mobile containers in human cognitive evolution studies: Understudied and underrepresented. Evol Anthropol. 2020 Aug 03;: Authors: Langley MC, Suddendorf T Abstract Mobile carrying devices-slings, bags, boxes, containers, etc.-are a ubiquitous tool form among recent human communities. So ingrained are they to our present lifeways that the fundamental relationship between mobile containers and foresight is easily overlooked, resulting...
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Midgut volvulus caused by intestinal malrotation; A rare cause of acute abdomen in adults. Case report. Int J Surg Case Rep. 2020 Jul 18;73:355-359 Authors: Perez Galaz F, Moedano Rico K, Pérez Tristán FA, Acuña Macouzet A, Jafif Cojab M Abstract INTRODUCTION: Acute abdomen due to midgut volvulus with intestinal malrotation is rare event with only only few cases in the literature Butterworth et al. (2018). Intestinal malrotation presented in...
Mandibular reconstruction using single piece zygomatic implant in conjunction with a reinforcing Fibular Graft Union: A case report. Int J Surg Case Rep. 2020 Jul 23;73:347-354 Authors: Gaur V, Doshi AG, Palka LR Abstract Presenting to our knowledge, for the first time in literature, a case report on the long term follow-up of an implant retained fixed prosthesis on free fibular reconstruction with a single piece zygomatic implant and single...
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Related Articles Managing radioiodine refractory thyroid cancer: the role of dosimetry and redifferentiation on subsequent I-131 therapy. Q J Nucl Med Mol Imaging. 2020 Sep;64(3):250-264 Authors: Dotinga M, Vriens D, van Velden F, Heijmen L, Nagarajah J, Hicks R, Kapiteijn E, de Geus-Oei LF Abstract Poor responses to iodine-131 (I-131) therapy can relate to either low iodine uptake and retention in thyroid cancer cells or to increased radioresistance....
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Choroid Plexus Cyst of the Fourth Ventricle associated with Intermittent Obstructive Hydrocephalus: Case Report. World Neurosurg. 2020 Jul 31;: Authors: Draghi R, Mongardi L, Panzacchi R, Godano U, Barni I, Calbucci F, Borghesi I Abstract BACKGROUND: Choroid plexus cysts (CPCs) are a type of neuroepithelial cysts, benign lesions located more frequently in the supratentorial compartment. Symptomatic CPCs in the posterior fossa are extremely...
Reconstruction of Complex Scalp Defect After Cirsoid Aneurysm Resection: A Multidisciplinary Approach. World Neurosurg. 2020 Jul 31;: Authors: Ung TH, Delcont MR, Colakoglu S, Seinfeld J, French B, Wilkinson CC Abstract BACKGROUND: Scalp arteriovenous malformations, also known as cirsoid aneurysms, are complex collections of directly communicating arteries and veins. As a cirsoid aneurysm grows, it may recruit blood supply from multiple intracranial...
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