Publication date: September 2020Source: Acta Histochemica, Volume 122, Issue 6Author(s): Stancho Stanchev, Boycho Landzhov, Georgi Kotov, Nikola Stamenov, Tihomir Dikov, Alexandar Iliev
Tue Aug 04, 2020 15:59
Introduction. Systemic manifestation of toxoplasmosis is commonly seen in immune-compromised individuals. Skin manifestations are seen commonly in conjunction with systemic features. Isolated cutaneous toxoplasmosis is extraordinarily rare in immunocompetent patients. Case Description. A 64-year-old female presented to the Dermatology Outpatient Department (OPD), with a nonhealing ulcer over dorsum of the left hand for one year. The patient did not have any systemic diseases. Serology tests were...
Tue Aug 04, 2020 10:05
Lung cancer is one of the most common solid cancers and represents the leading cause of cancer death worldwide. Over the last decade, research on the epithelial-mesenchymal transition (EMT) in lung cancer has gained increasing attention. Here, we review clinical and histological features of non-small-cell lung cancer associated with EMT. We then aimed to establish potential clinical implications of EMT in current therapeutic options, including surgery, radiation, targeted therapy against oncogenic...
Tue Aug 04, 2020 10:49
Zusammenfassung Autoimmune Lebererkrankungen umfassen ein Spektrum idiopathischer fortschreitender Leberentzündungen mit im Einzelfall histologisch kennzeichnenden Befunden. Hierzu gehören bei der autoimmunen Hepatitis (AIH) das Bild einer chronischen Hepatitis mit plasmazellreicher dominierender Grenzflächenaktivität, Rosettierung der Hepatozyten und Emperipolese, bei der primären biliären Cholangitis (PBC) chronische, nichteitrige, destruierende Gallengangsläsionen, bei der...
Tue Aug 04, 2020 03:00
Abstract Background Fine needle aspiration cytopathology (FNAC) is the most reliable tool for evaluating thyroid nodules. However, diagnosing Bethesda category III, atypia/follicular lesion of undetermined significance (AUS/FLUS), is a major limitation. The aim of this study was to evaluate the risk of malignancy (RoM) in AUS/FLUS nodules. A systematic review was also carried out analyzing the largest series. Methods Totally 1750 cases (9%) diagnosed with AUS/FLUS were evaluated retrospectively...
Mon Aug 03, 2020 19:06
Publication date: Available online 3 August 2020Source: Human PathologyAuthor(s): Haley Sechrist, Akisha Glasgow, Philip Bomeisl, Hannah Gilmore, Aparna Harbhajanka
Tue Aug 04, 2020 19:59
Abstract Urachal carcinoma (UrC) is a rare tumor with remarkable histological and molecular similarities to colorectal cancer (CRC). Adenomatous polyposis coli (APC) is the most frequently affected gene in CRC, but the prevalence and significance of its alterations in UrC is poorly understood. In addition, loss of phosphatase and tensin homologue (PTEN) was shown to be associated with therapy resistance in CRC. Our primary aim was to assess specific genetic alterations including...
Tue Aug 04, 2020 03:00
Publication date: Available online 4 August 2020Source: Pathology - Research and PracticeAuthor(s): Guocheng Huang, Huijuan Li, Jingyao Wang, Xiqi Peng, Kaihao Liu, Liwen Zhao, Chunduo Zhang, Xuan Chen, Yongqing Lai, Liangchao Ni
Tue Aug 04, 2020 13:53
Publication date: Available online 4 August 2020Source: Pathology - Research and PracticeAuthor(s): Chenghao Lu, Zheyu Yang, Dingye Yu, Jianwei Lin, Wei Cai
Tue Aug 04, 2020 13:53
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