Antibiotics, Vol. 9, Pages 302: Proteomic Characterization of Antibiotic Resistance, and Production of Antimicrobial and Virulence Factors in Streptococcus Species Associated with Bovine Mastitis. Could Enzybiotics Represent Novel Therapeutic Agents Against These Pathogens? Antibiotics doi: 10.3390/antibiotics9060302 Authors: Ana G. Abril Mónica Carrera Karola Böhme Jorge Barros-Velázquez José-Luis R. Rama Pilar Calo-Mata Angeles Sánchez-Pérez Tomás G. Villa Streptococcus...
Thu Jun 04, 2020 03:00
Antibiotics, Vol. 9, Pages 300: A Silkworm Infection Model for In Vivo Study of Glycopeptide Antibiotics Antibiotics doi: 10.3390/antibiotics9060300 Authors: Montali Berini Brivio Mastore Saviane Cappellozza Marinelli Tettamanti Glycopeptide antibiotics (GPAs) are drugs of last resort for treating infections by Gram-positive bacteria. They inhibit bacterial cell wall assembly by binding to the d-Ala-d-Ala terminus of peptidoglycan precursors, leading to cell...
Thu Jun 04, 2020 03:00
Antibiotics, Vol. 9, Pages 301: Growing Trend of Fighting Infections in Aquaculture Environment—Opportunities and Challenges of Phage Therapy Antibiotics doi: 10.3390/antibiotics9060301 Authors: Kowalska Kazimierczak Sowińska Wójcik Siwicki Dastych Phage therapy, a promising alternative to antimicrobial treatment of bacterial diseases, is getting more and more popular, especially due to the rising awareness of antibiotic resistance and restrictions in antibiotics’...
Thu Jun 04, 2020 03:00
Antioxidants, Vol. 9, Pages 491: Cathelicidin Modulates Vascular Smooth Muscle Cell Phenotypic Switching through ROS/IL-6 Pathway Antioxidants doi: 10.3390/antiox9060491 Authors: Xiaoliang Dong Di Wu Yihan Zhang Lingling Jia Xiaohua Pan Jia Sun Li-Long Pan Vascular smooth muscle cells (VSMC) are stromal cells of the blood vessels and their differentiation is thought to be essential during atherosclerosis. Cathelicidin-related antimicrobial peptides (CRAMP) are suggested...
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Antioxidants, Vol. 9, Pages 490: MnTE-2-PyP Suppresses Prostate Cancer Cell Growth via H2O2 Production Antioxidants doi: 10.3390/antiox9060490 Authors: Yuxiang Zhu Elizabeth A. Kosmacek Arpita Chatterjee Rebecca E. Oberley-Deegan Prostate cancer patients are often treated with radiotherapy. MnTE-2-PyP, a superoxide dismutase (SOD) mimic, is a known radioprotector of normal tissues. Our recent work demonstrated that MnTE-2-PyP also inhibits prostate cancer progression with radiotherapy;...
Thu Jun 04, 2020 03:00
Antioxidants, Vol. 9, Pages 488: Schisandra rubriflora Plant Material and In Vitro Microshoot Cultures as Rich Sources of Natural Phenolic Antioxidants Antioxidants doi: 10.3390/antiox9060488 Authors: Agnieszka Szopa Michał Dziurka Sebastian Granica Marta Klimek-Szczykutowicz Paweł Kubica Angelika Warzecha Karolina Jafernik Halina Ekiert Schisandra rubriflora is a dioecious, underestimated medicinal plant species known from traditional Chinese medicine. The present...
Thu Jun 04, 2020 03:00
Antioxidants, Vol. 9, Pages 489: Cold-Pressed Nigella Sativa Oil Standardized to 3% Thymoquinone Potentiates Omega-3 Protection against Obesity-Induced Oxidative Stress, Inflammation, and Markers of Insulin Resistance Accompanied with Conversion of White to Beige Fat in Mice Antioxidants doi: 10.3390/antiox9060489 Authors: Hsin Hsueh Shen Stephen J. Peterson Lars Bellner Abu Choudhary Lior Levy Leah Gancz Ariel Sasson Joseph Trainer Rita Rezzani Abraham Resnick David...
Thu Jun 04, 2020 03:00
Atmosphere, Vol. 11, Pages 596: Fog Classification by Their Droplet Size Distributions: Application to the Characterization of Cerema’s Platform Atmosphere doi: 10.3390/atmos11060596 Authors: Pierre Duthon Michèle Colomb Frédéric Bernardin Fog is one of major challenges for transportation systems. The automation of the latter is based on perception sensors that can be disrupted by atmospheric conditions. As fog conditions are random and non-reproducible in nature, Cerema has designed...
Thu Jun 04, 2020 03:00
Atmosphere, Vol. 11, Pages 597: Embodied CO2 Emission Changes in Manufacturing Trade: Structural Decomposition Analysis of China, Japan, and Korea Atmosphere doi: 10.3390/atmos11060597 Authors: Yoon Kim Kim This study investigated the driving factors of embodied carbon emission changes in manufacturing trades through structural decomposition analysis. For empirical analysis, we developed an environmental multiregional input–output model for Korea, Japan, and China...
Thu Jun 04, 2020 03:00
Atmosphere, Vol. 11, Pages 592: Impact of Model Resolution and Initial/Boundary Conditions in Forecasting Flood-Causing Precipitations Atmosphere doi: 10.3390/atmos11060592 Authors: Francesco Ferrari Federico Cassola Peter Enos Tuju Alessandro Stocchino Paolo Brotto Andrea Mazzino In late summer and autumn Mediterranean coastal regions are quite regularly affected by small-scale, flood-producing convective systems. The complexity of mesoscale triggering mechanisms, related...
Thu Jun 04, 2020 03:00
Atmosphere, Vol. 11, Pages 594: The Use of a Numerical Weather Prediction Model to Simulate Near-Field Volcanic Plumes Atmosphere doi: 10.3390/atmos11060594 Authors: Burton Woodhouse Gadian Mobbs In this paper, a state-of the art numerical weather prediction (NWP) model is used to simulate the near-field plume of a Plinian-type volcanic eruption. The NWP model is run at very high resolution (of the order of 100 m) and includes a representation of physical processes, including...
Thu Jun 04, 2020 03:00
Atmosphere, Vol. 11, Pages 593: Performance of KMA-ADAM3 in Identifying Asian Dust Days over Northern China Atmosphere doi: 10.3390/atmos11060593 Authors: Ryoo Kim Cho Recently, the Korea Meteorological Administration developed Asian Dust Aerosol Model version 3 (ADAM3) by incorporating additional parameters into ADAM2, including anthropogenic particulate matter (PM) emissions, modification of dust generation by considering real-time surface vegetation, and assimilations of...
Thu Jun 04, 2020 03:00
Atmosphere, Vol. 11, Pages 595: Impact of Climate Change on Olive Crop Production in Italy Atmosphere doi: 10.3390/atmos11060595 Authors: Orlandi Rojo Picornell Oteros Pérez-Badia Fornaciari The effects of climate change on agricultural systems raise important uncertainties about the future productivity and suitability of crops, especially in areas suffering from intense environmental changes. Olive groves occupy Mediterranean areas characterized by seasonal temporary...
Thu Jun 04, 2020 03:00
Atmosphere, Vol. 11, Pages 591: Projected Direct Carbon Dioxide Emission Reductions as a Result of the Adoption of Electric Vehicles in Gauteng Province of South Africa Atmosphere doi: 10.3390/atmos11060591 Authors: Moeletsi Tongwane There are genuine worldwide concerns regarding the contribution of internal combustion engine (ICE) vehicles to greenhouse gas (GHG) emissions. Passenger electric vehicles (EVs) are considered as a viable solution to the rapidly increasing global GHG...
Thu Jun 04, 2020 03:00
Bioengineering, Vol. 7, Pages 51: Influence of Enzyme Additives on the Rheological Properties of Digester Slurry and on Biomethane Yield Bioengineering doi: 10.3390/bioengineering7020051 Authors: Liane Müller Nils Engler Kay Rostalsky Ulf Müller Christian Krebs Sandra Hinz The use of enzyme additives in anaerobic digestion facilities has increased in recent years. According to the manufacturers, these additives should increase or accelerate the biogas yield and reduce...
Thu Jun 04, 2020 03:00
Biomedicines, Vol. 8, Pages 152: A Human DUB Protein Array for Clarification of Linkage Specificity of Polyubiquitin Chain and Application to Evaluation of Its Inhibitors Biomedicines doi: 10.3390/biomedicines8060152 Authors: Hirotaka Takahashi Satoshi Yamanaka Shohei Kuwada Kana Higaki Kohki Kido Yusuke Sato Shuya Fukai Fuminori Tokunaga Tatsuya Sawasaki Protein ubiquitinations play pivotal roles in many cellular processes, including homeostasis, responses to...
Thu Jun 04, 2020 03:00
Biomedicines, Vol. 8, Pages 151: Considering the Experimental use of Temozolomide in Glioblastoma Research Biomedicines doi: 10.3390/biomedicines8060151 Authors: Verena J. Herbener Timo Burster Alicia Goreth Maximilian Pruss Hélène von von Bandemer Tim Baisch Rahel Fitzel Markus D. Siegelin Georg Karpel-Massler Klaus-Michael Debatin Mike-Andrew Westhoff Hannah Strobel Temozolomide (TMZ) currently remains the only chemotherapeutic component in the approved...
Thu Jun 04, 2020 03:00
Biomimetics, Vol. 5, Pages 25: Biomimicry of the Hawk Moth, Manduca sexta (L.), Produces an Improved Flapping-Wing Mechanism Biomimetics doi: 10.3390/biomimetics5020025 Authors: Kenneth Moses Mark Willis Roger Quinn Flapping-wing micro air vehicles (FWMAVs) that mimic the flight capabilities of insects have been sought for decades. Core to the vehicle’s flight capabilities is the mechanism that drives the wings to produce thrust and lift. This article describes a newly...
Thu Jun 04, 2020 03:00
Biomolecules, Vol. 10, Pages 861: Endothelial Dysfunction May Link Interatrial Septal Abnormalities and MTHFR-Inherited Defects to Cryptogenic Stroke Predisposition Biomolecules doi: 10.3390/biom10060861 Authors: Luca Sgarra Alessandro Santo Bortone Maria Assunta Potenza Carmela Nacci Maria Antonietta De Salvia Tommaso Acquaviva Emanuela De Cillis Marco Matteo Ciccone Massimo Grimaldi Monica Montagnani We explored the significance of the L-Arginine/asymmetric...
Thu Jun 04, 2020 03:00
Biomolecules, Vol. 10, Pages 858: Efficacy Assessment of an Uncharged Reactivator of NOP-Inhibited Acetylcholinesterase Based on Tetrahydroacridine Pyridine-Aldoxime Hybrid in Mouse Compared to Pralidoxime Biomolecules doi: 10.3390/biom10060858 Authors: André-Guilhem Calas Anne-Sophie Hanak Nina Jaffré Aurélie Nervo José Dias Catherine Rousseau Charlotte Courageux Xavier Brazzolotto Pascal Villa Adeline Obrecht Jean-François Goossens Christophe Landry Johan...
Thu Jun 04, 2020 03:00
Biomolecules, Vol. 10, Pages 860: Thymus vulgaris L. Essential Oil Solid Formulation: Chemical Profile and Spasmolytic and Antimicrobial Effects Biomolecules doi: 10.3390/biom10060860 Authors: Matteo Micucci Michele Protti Rita Aldini Maria Frosini Ivan Corazza Carla Marzetti Laura Beatrice Mattioli Gabriella Tocci Alberto Chiarini Laura Mercolini Roberta Budriesi A new Thymus vulgaris L. solid essential oil (SEO) formulation composed of liquid EO linked...
Thu Jun 04, 2020 03:00
Biomolecules, Vol. 10, Pages 859: LOMIX, a Mixture of Flaxseed Linusorbs, Exerts Anti-Inflammatory Effects through Src and Syk in the NF-κB Pathway Biomolecules doi: 10.3390/biom10060859 Authors: Zubair Ahmed Ratan Deok Jeong Nak Yoon Sung Youn Young Shim Martin J. T. Reaney Young-Su Yi Jae Youl Cho Although flax (Linum usitatissimum L.) has long been used as Ayurvedic medicine, its anti-inflammatory role is still unclear. Therefore, we aimed to investigate the anti-inflammatory...
Thu Jun 04, 2020 03:00
Biomolecules, Vol. 10, Pages 857: A Computational Approach with Biological Evaluation: Combinatorial Treatment of Curcumin and Exemestane Synergistically Regulates DDX3 Expression in Cancer Cell Lines Biomolecules doi: 10.3390/biom10060857 Authors: Shailima Rampogu Seong Min Kim Minky Son Ayoung Baek Chanin Park Gihwan Lee Yumi Kim Gon Sup Kim Ju Hyun Kim Keun Woo Lee DDX3 belongs to RNA helicase family that demonstrates oncogenic properties and has gained...
Thu Jun 04, 2020 03:00
Biomolecules, Vol. 10, Pages 856: Comparative Characterization of Plasmodium falciparum Hsp70-1 Relative to E. coli DnaK Reveals the Functional Specificity of the Parasite Chaperone Biomolecules doi: 10.3390/biom10060856 Authors: Charity Mekgwa Lebepe Pearl Rutendo Matambanadzo Xolani Henry Makhoba Ikechukwu Achilonu Tawanda Zininga Addmore Shonhai Hsp70 is a conserved molecular chaperone. How Hsp70 exhibits specialized functions across species remains to be understood....
Thu Jun 04, 2020 03:00
Biomolecules, Vol. 10, Pages 855: Targeting the Endocannabinoid CB1 Receptor to Treat Body Weight Disorders: A Preclinical and Clinical Review of the Therapeutic Potential of Past and Present CB1 Drugs Biomolecules doi: 10.3390/biom10060855 Authors: Thomas Murphy Bernard Le Foll Obesity rates are increasing worldwide and there is a need for novel therapeutic treatment options. The endocannabinoid system has been linked to homeostatic processes, including metabolism, food intake, and...
Thu Jun 04, 2020 03:00
Brain Sciences, Vol. 10, Pages 346: Osteopontin and Integrin Mediated Modulation of Post-Synapses in HIV Envelope Glycoprotein Exposed Hippocampal Neurons Brain Sciences doi: 10.3390/brainsci10060346 Authors: Farina J. Mahmud Thomas Boucher Shijun Liang Amanda M. Brown The advent of Human Immunodeficiency Virus (HIV) antiretrovirals have reduced the severity of HIV related neurological comorbidities but they nevertheless remain prevalent. Synaptic degeneration due to the action...
Thu Jun 04, 2020 03:00
Brain Sciences, Vol. 10, Pages 347: Effort-Based Decision-Making and Gross Motor Performance: Are They Linked? Brain Sciences doi: 10.3390/brainsci10060347 Authors: Simone V. Gill Samuel J. Abplanalp Laura Keegan Daniel Fulford The purpose of this study was to investigate the relationship between effort-based decision making and gross motor performance. Effort-based decision making was measured using a modified version of the Effort Expenditure for Rewards Task (EEfRT), in which...
Thu Jun 04, 2020 03:00
Brain Sciences, Vol. 10, Pages 345: COVID-19 Immunopathology and the Central Nervous System: Implication for Multiple Sclerosis and Other Autoimmune Diseases with Associated Demyelination Brain Sciences doi: 10.3390/brainsci10060345 Authors: Marina Kleopatra Boziki Alexios-Fotios A. Mentis Maria Shumilina Gleb Makshakov Evgeniy Evdoshenko Nikolaos Grigoriadis In the frame of the coronavirus disease 2019 (COVID-19) pandemic, recent reports on SARS-CoV-2 potential neuroinvasion...
Thu Jun 04, 2020 03:00
Cancers, Vol. 12, Pages 1466: The Progression of Acute Myeloid Leukemia from First Diagnosis to Chemoresistant Relapse: A Comparison of Proteomic and Phosphoproteomic Profiles Cancers doi: 10.3390/cancers12061466 Authors: Elise Aasebø Frode S. Berven Randi Hovland Stein Ove Døskeland Øystein Bruserud Frode Selheim Maria Hernandez-Valladares Acute myeloid leukemia (AML) is an aggressive hematological malignancy. Nearly 50% of the patients who receive the most intensive...
Thu Jun 04, 2020 03:00
Cancers, Vol. 12, Pages 1472: The Expression, Functions and Mechanisms of Circular RNAs in Gynecological Cancers Cancers doi: 10.3390/cancers12061472 Authors: Peixin Dong Daozhi Xu Ying Xiong Junming Yue Kei Ihira Yosuke Konno Hidemichi Watari Circular RNAs (circRNAs) are covalently closed, endogenous non-coding RNAs and certain circRNAs are linked to human tumors. Owing to their circular form, circRNAs are protected from degradation by exonucleases, and therefore,...
Thu Jun 04, 2020 03:00
Cancers, Vol. 12, Pages 1467: ImmunoPET in Multiple Myeloma—What? So What? Now What? Cancers doi: 10.3390/cancers12061467 Authors: Clément Bailly Benjamin Chalopin Sébastien Gouard Thomas Carlier Patricia Remaud-Le Saëc Séverine Marionneau-Lambot Philippe Moreau Cyrille Touzeau Françoise Kraeber-Bodere Caroline Bodet-Milin Michel Chérel Despite constant progress over the past three decades, multiple myeloma (MM) is still an incurable disease, and the identification...
Thu Jun 04, 2020 03:00
Cancers, Vol. 12, Pages 1471: Clinical Validation Results of an Innovative Non-Invasive Device for Colorectal Cancer Preventive Screening through Fecal Exhalation Analysis Cancers doi: 10.3390/cancers12061471 Authors: Giulia Zonta Cesare Malagù Sandro Gherardi Alessio Giberti Alessandro Pezzoli Aldo De Togni Caterina Palmonari Screening is recommended to reduce both incidence and mortality of colorectal cancer. Currently, many countries employ fecal occult blood test...
Thu Jun 04, 2020 03:00
Cancers, Vol. 12, Pages 1464: The miR-26b-5p/KPNA2 Axis Is an Important Regulator of Burkitt Lymphoma Cell Growth Cancers doi: 10.3390/cancers12061464 Authors: Fubiao Niu Marta Kazimierska Ilja M. Nolte Miente Martijn Terpstra Debora de Jong Jasper Koerts Tineke van der Sluis Bea Rutgers Ryan M. O’Connell Klaas Kok Anke van den Berg Agnieszka Dzikiewicz-Krawczyk Joost Kluiver The expression of several microRNAs (miRNAs) is known to be changed in Burkitt...
Thu Jun 04, 2020 03:00
Cancers, Vol. 12, Pages 1469: Prognostic Value of Peripheral Blood Lymphocyte Telomere Length in Gynecologic Malignant Tumors Cancers doi: 10.3390/cancers12061469 Authors: Kamrunnahar Shanta Kentaro Nakayama Masako Ishikawa Tomoka Ishibashi Hitomi Yamashita Seiya Sato Hiroki Sasamori Kiyoka Sawada Sonomi Kurose Hossain Mohammad Mahmud Sultana Razia Kouji Iida Noriyoshi Ishikawa Satoru Kyo Background: Lymphocyte telomere length is strongly correlated...
Thu Jun 04, 2020 03:00
Cancers, Vol. 12, Pages 1468: Potential Onco-Suppressive Role of miR122 and miR144 in Uveal Melanoma through ADAM10 and C-Met Inhibition Cancers doi: 10.3390/cancers12061468 Authors: Adriana Amaro Michela Croce Silvano Ferrini Gaia Barisione Marina Gualco Patrizia Perri Ulrich Pfeffer Martine J. Jager Sarah E. Coupland Carlo Mosci Gilberto Filaci Marina Fabbi Paola Queirolo Rosaria Gangemi Uveal melanoma (UM) is a rare tumor of the eye that leads...
Thu Jun 04, 2020 03:00
Cancers, Vol. 12, Pages 1470: An Overview of Candidate Therapeutic Target Genes in Ovarian Cancer Cancers doi: 10.3390/cancers12061470 Authors: Elena Alexandrova Giovanni Pecoraro Assunta Sellitto Viola Melone Carlo Ferravante Teresa Rocco Anna Guacci Giorgio Giurato Giovanni Nassa Francesca Rizzo Alessandro Weisz Roberta Tarallo Ovarian cancer (OC) shows the highest mortality rate among gynecological malignancies and, because of the absence of specific...
Thu Jun 04, 2020 03:00
Cancers, Vol. 12, Pages 1465: Effect of Serum SPARC Levels on Survival in Patients with Digestive Tract Cancer: A Post Hoc Analysis of the AMATERASU Randomized Clinical Trial Cancers doi: 10.3390/cancers12061465 Authors: Taisuke Akutsu Eisaku Ito Mitsuo Narita Hironori Ohdaira Yutaka Suzuki Mitsuyoshi Urashima Observational studies suggest that physical activity may improve, whereas sarcopenia may worsen the survival of cancer patients. It has been suggested that secreted...
Thu Jun 04, 2020 03:00
Cancers, Vol. 12, Pages 1463: Interleukins 4 and 13 and Their Receptors Are Differently Expressed in Gastrointestinal Tract Cancers, Depending on the Anatomical Site and Disease Advancement, and Improve Colon Cancer Cell Viability and Motility Cancers doi: 10.3390/cancers12061463 Authors: Iwona Bednarz-Misa Dorota Diakowska Izabela Szczuka Paulina Fortuna Agnieszka Kubiak Joanna Rosińczuk Małgorzata Krzystek-Korpacka Immunosuppressive interleukins (IL)-4 and 13 may...
Thu Jun 04, 2020 03:00
Cancers, Vol. 12, Pages 1461: PDX1 DNA Methylation Distinguishes Two Subtypes of Pancreatic Neuroendocrine Neoplasms with a Different Prognosis Cancers doi: 10.3390/cancers12061461 Authors: Gitta Boons Timon Vandamme Joe Ibrahim Geert Roeyen Ann Driessen Dieter Peeters Ben Lawrence Cristin Print Marc Peeters Guy Van Camp Ken Op de Beeck DNA methylation is a crucial epigenetic mechanism for gene expression regulation and cell differentiation. Furthermore,...
Thu Jun 04, 2020 03:00
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