Abstract There is growing evidence that MRI-ultrasound (MR-US)-targeted biopsy (TB) has high detection rates of clinically significant prostate cancer (PCa) compared to standard transrectal ultrasound (TRUS)-guided biopsy. A radiologist plays a significant role in MR-US fusion biopsy planning. Here, we discuss six simple steps that can help set up a successful MR-US fusion biopsy program in collaboration with the urologist.
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Abstract Purpose With the spread of transjugular intrahepatic portosystemic shunts (TIPS), portosystemic shunt surgery (PSSS) has decreased and leaves more complex patients with great demands for accurate preoperative planning. The aim was to evaluate the role of imaging for predicting the most suitable PSSS approach. Material and methods Forty-four patients...
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Publication date: Available online 4 June 2020Source: Auris Nasus LarynxAuthor(s): Ryosuke Sato, Nobuyuki Bandoh, Takashi Goto, Akihiro Uemura, Nobuyuki Inoue, Yuki Otomo, Hiroshi Nakano, Tomomi Yamaguchi, Yasutaka Kato, Hiroshi Nishihara, Hidehiro Takei, Yasuaki Harabuchi
Thu Jun 04, 2020 19:17
Publication date: Available online 4 June 2020Source: Auris Nasus LarynxAuthor(s): Elżbieta Niemczyk, Magdalena Lachowska, Emanuel Tataj, Katarzyna Kurczak, Kazimierz Niemczyk
Thu Jun 04, 2020 19:17
Cure rates among children and adolescents with high-grade, mature B-cell non-Hodgkin’s lymphoma (mainly Burkitt’s lymphoma but also diffuse large B-cell lymphoma) have dramatically improved over the past 30 years, with trials showing survival of approximately 90%. However, well-known prognostic…
Thu Jun 04, 2020 03:00
Thu Jun 04, 2020 14:48
Thu Jun 04, 2020 14:45
Key points The interatrial conduction, including Bachmann's bundle, the posterior septal conduction, the anterior septal conduction, and the cavo‐tricuspid isthmus, contributes to the maintenance mechanisms of atrial fibrillation in a 3D‐biatrial model. The interatrial conduction ablation including a cavo‐tricuspid isthmus ablation significantly affects the wave dynamics of atrial fibrillation (AF) and facilitates the AF termination or atrial tachycardia conversion of the AF after the circumferential...
Thu Jun 04, 2020 12:51
Abstract The E‐cigarette market continues to expand at an alarming rate with thousands of flavours available for purchase and continuously evolving devices. Now a multi‐billion dollar industry and one without stringent regulation, there is rising concern over the safety of vaping products. Since June 2019, over 2800 cases of E‐cigarette associated acute lung toxicity have been reported in the USA, over 60 of which resulted in death. Many argue that E‐cigarettes offer a safer alternative to smoking,...
Wed Jun 03, 2020 21:44
Related ArticlesSomething to Sweat About: Two Cases of Dupilumab-Induced Hyperhidrosis and Bromhidrosis. Allergy Rhinol (Providence). 2020 Jan-Dec;11:2152656720927703 Authors: Rowane M, Valencia R, Schend J, Jhaveri D, Hostoffer R Abstract Introduction: Atopic dermatitis (AD, eczema) is familial chronic inflammatory skin disease of complex etiology and increasing prevalence. Dupilumab is an IL-4 receptor subunit alpha (IL-4Rα) antagonist that is...
Thu Jun 04, 2020 19:09
Publication date: Available online 4 June 2020Source: American Journal of Infection ControlAuthor(s): Jordan Seaver, Keith Grant, James Lunn, Peter Sandor, Pamela Moran, David S. Shapiro
Thu Jun 04, 2020 19:08
Publication date: Available online 3 June 2020Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): Matthew Greenhawt
Thu Jun 04, 2020 19:07
Abstract In this study, we explored expression and functions of circular RNA LPAR3 (circLPAR3) in esophageal squamous cell carcinoma (ESCC). The differential expression of circRNAs in 10 ESCC and corresponding para‐carcinoma tissues was analyzed through circRNA microarray, then the candidate circRNAs were detected and verified through qRT‐PCR, and a novel circRNA was screened, which was circLPAR3. CircLPAR3 showed apparently high expression in ESCC tissues and cells, which was closely correlated...
Thu Jun 04, 2020 12:34
Abstract The expression of classical HLA class I antigens (HLA‐I) on the surfaces of cancer cells allows cytotoxic T cells to recognize and eliminate these cells. Reduction or loss of HLA‐I is a mechanism of escape from antitumor immunity. The present study aimed to investigate the clinicopathological impacts of HLA‐I and non‐classical HLA‐I antigens expressed on pancreatic ductal adenocarcinoma (PDAC) cells. We performed immunohistochemistry to detect expression of HLA‐I antigens in PDAC using...
Wed Jun 03, 2020 21:30
Abstract Whether germline (g) breast cancer susceptibility gene (BRCA ) mutations are located within or outside the ovarian cancer cluster region (OCCR; 1380–4062 bp for gBRCA1 , and between 3249–5681 bp and 6645–7471 bp for gBRCA2 ) may influence risk variations for ovarian cancers. This ad hoc analysis of the CHARLOTTE epidemiological study in Japan assessed the distribution of gBRCA1/2 mutations in patients with newly diagnosed ovarian cancer, and investigated an association between gBRCA1/2...
Wed Jun 03, 2020 21:10
Abstract Neuroblastoma (NB) is a childhood malignancy originating from the sympathetic nervous system, which accounts for approximately 15% of all pediatric cancer‐related deaths. As the 5‐year survival rate of patients with high‐risk NB is < 50%, novel therapeutic strategies for NB patients are urgently required. Nonaethylene glycol mono (‘4‐iodo‐4‐biphenyl) ester (9bw) is a polyethylene glycol derivative, synthesized by modifying a compound originally extracted from filamentous bacteria. Although...
Wed Jun 03, 2020 21:00
Abstract We conducted an early phase II study of mixed 19‐peptide cancer vaccine monotherapy for 14 advanced metastatic triple‐negative breast cancer (mTNBC) patients refractory to systemic chemotherapy to develop a new type of cancer vaccine. The treatment protocol consisted of a weekly vaccination for 6 weeks, and there were no severe adverse events related to the vaccination throughout the trial. Increase of peptide‐specific immunoglobulin G against the vaccinated human leukocyte antigen (HLA)‐matched...
Wed Jun 03, 2020 20:36
Publication date: Available online 3 June 2020Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Albert Mudry, John Riddington Young
Thu Jun 04, 2020 19:02
Publication date: Available online 3 June 2020Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): liu Jia, chen Cao, bi Jing, zhao Zigai, xu Bin, chen Xiaowei, lin Lexi, dai Jiren, zhang Yang, fu Yong
Thu Jun 04, 2020 19:02
Publication date: Available online 3 June 2020Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Li-Ming Sun, Yuan Xu, Meng-Nan Xu, Min Wang, Yu Su, Si-Ming Yuan
Thu Jun 04, 2020 19:02
Publication date: Available online 3 June 2020Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Jianyong Chen, Yao Chen, Qing Zhang, Xiaobao Ma, Ling Mei, Wei Wang, Jiali Shen, Qin Zhang, Lu Wang, Min Shen, Kuan He, Xiangping Chen, Jun Yang
Thu Jun 04, 2020 19:02
An amendment to this paper has been published and can be accessed via the original article.
Tue Jun 02, 2020 03:00
A recent increase in children admitted with hypotensive shock and fever in the context of the COVID-19 outbreak requires an urgent characterization and assessment of the involvement of SARS-CoV-2 infection. Th...
Mon Jun 01, 2020 03:00
Mon Jun 01, 2020 03:00
Survival benefit from low tidal volume (VT) ventilation (LTVV) has been demonstrated for patients with acute respiratory distress syndrome (ARDS), and patients not having ARDS could also benefit from this strateg...
Mon Jun 01, 2020 03:00
In Reply Lin and Sol refer to some limitations in our study. First we fully agree that the study, as every study, has its limitations. They assume that facial palsy may influence socioeconomic status and therefore health-related quality of life (HRQoL). We performed additional univariate analyses to explore this assumption. We found no significant associations between facial palsy severity (Sunnybrook score) and socioeconomic status operationalized as income, occupational status, and education. In...
Thu Jun 04, 2020 03:00
This cross-sectional cohort study uses census data to approximate population estimates of obstructive eustachian tube dysfunction among US adolescents.
Thu Jun 04, 2020 03:00
This cohort study evaluates the use of therapeutic nasal positive airway pressure response during drug-induced sleep endoscopy as a predictor of the success of subsequent hypoglossal nerve stimulation.
Thu Jun 04, 2020 03:00
This Viewpoint identifies concerns and potential solutions for aspiring otolaryngology–head and neck surgeons and otolaryngology departments in the residency match process during the COVID-19 pandemic.
Thu Jun 04, 2020 03:00
To the Editor Bruins et al performed a cross-sectional analysis of a sample of patients with facial palsy who had undergone surgery to ascertain the association between socioeconomic and personality factors with health-related quality-of-life (HRQoL). The authors reported that age, bilateral facial palsy, severity of facial palsy, mental distress, and personality traits were associated with HRQoL in patients with long-standing facial palsy.
Thu Jun 04, 2020 03:00
Related ArticlesMechanism of action of HTX-011: a novel, extended-release, dual-acting local anesthetic formulation for postoperative pain. Reg Anesth Pain Med. 2020 Jun 02;: Authors: Hafer J, Johnson KB PMID: 32487705 [PubMed - as supplied by publisher]
Thu Jun 04, 2020 18:58
Related ArticlesReply to Tognù et al: regional anesthesia for proximal humerus surgery during COVID-19 pandemic. Reg Anesth Pain Med. 2020 Jun 02;: Authors: Mistry T, Kuppusamy E PMID: 32487704 [PubMed - as supplied by publisher]
Thu Jun 04, 2020 18:58
Related ArticlesResponse to the letter to the editor by Hafer and Johnson concerning 'Mechanism of action of HTX-011: a novel, extended-release, dual-acting local anesthetic formulation for postoperative pain'. Reg Anesth Pain Med. 2020 Jun 02;: Authors: Ottoboni T, Quart B, Pawasauskas J, Dasta JF, Pollak RA, Viscusi ER PMID: 32487703 [PubMed - as supplied by publisher]
Thu Jun 04, 2020 18:58
Related ArticlesRapid sequence spinal must be the new norm for an emergency LSCS in this Covid pandemic. Reg Anesth Pain Med. 2020 Jun 02;: Authors: Wagh HD PMID: 32487702 [PubMed - as supplied by publisher]
Thu Jun 04, 2020 18:58
Publication date: Available online 3 June 2020Source: Dental MaterialsAuthor(s): G.C. Porter, G.R. Tompkins, D.R. Schwass, K.C. Li, J.N. Waddell, C.J. Meledandri
Thu Jun 04, 2020 18:57
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