Related ArticlesAS1411-conjugated gold nanoparticles affect cell proliferation through a mechanism that seems independent of nucleolin. Nanomedicine. 2019 10;21:102060 Authors: Kabirian-Dehkordi S, Chalabi-Dchar M, Mertani HC, Le Guellec D, Verrier B, Diaz JJ, Mehrgardi MA, Bouvet P Abstract G-rich oligonucleotide, AS1411, has been shown to interact with nucleolin and to inhibit cancer cell proliferation and tumor growth. This antiproliferative action...
Thu Jun 04, 2020 13:29
Related ArticlesApical assemblies of intermediate filament-like protein FilP are highly dynamic and affect polar growth determinant DivIVA in Streptomyces venezuelae. Mol Microbiol. 2019 07;112(1):47-61 Authors: Fröjd MJ, Flärdh K Abstract Streptomyces spp. grow as branching hyphae, building the cell wall in restricted zones at hyphal tips. The organization of this mode of polar growth involves three coiled-coil proteins: DivIVA and Scy, which form...
Thu Jun 04, 2020 13:29
Related ArticlesStatPearls Book. 2020 01 Authors: Abstract A somatic mutation describes any alteration at the cellular level in somatic tissues occurring after fertilization. These mutations do not involve the germline and consequently do not pass on to offspring. Somatic mutations are a normal part of aging and occur throughout an organism’s life cycle either spontaneously as a result of errors in DNA repair mechanisms or a direct response to stress. Mutations occurring...
Thu Jun 04, 2020 15:27
Related ArticlesGender awareness among medical students in a Swiss University. BMC Med Educ. 2020 Jun 03;20(1):156 Authors: Rrustemi I, Locatelli I, Schwarz J, Lagro-Janssen T, Fauvel A, Clair C Abstract BACKGROUND: Gender is an important social determinant, that influences healthcare. The lack of awareness on how gender influences health might lead to gender bias and can contribute to substandard patient care. Our objectives were to assess gender sensitivity...
Thu Jun 04, 2020 13:23
Related ArticlesAnalyzing the interaction of main components of hidden curriculum in medical education using interpretive structural modeling method. BMC Med Educ. 2020 Jun 01;20(1):176 Authors: Sarikhani Y, Shojaei P, Rafiee M, Delavari S Abstract BACKGROUND: Hidden curriculum (HC) is considered as unintended learning experiences in medical education (ME). This may include values, norms, beliefs, skills, and knowledge which could potentially influence...
Thu Jun 04, 2020 13:23
Related ArticlesMeasuring social interdependence in collaborative learning: instrument development and validation. BMC Med Educ. 2020 Jun 01;20(1):177 Authors: Shimizu I, Kikukawa M, Tada T, Kimura T, Duvivier R, van der Vleuten C Abstract BACKGROUND: In health professions education, several collaborative learning approaches have been used. As collaborative learning has a theoretical background of social interdependence theory, a theory informed and...
Thu Jun 04, 2020 13:23
Related ArticlesLeadership training programs in graduate medical education: a systematic review. BMC Med Educ. 2020 Jun 02;20(1):175 Authors: Kumar B, Swee ML, Suneja M Abstract BACKGROUND: With the increasing recognition that leadership skills can be acquired, there is a heightened focus on incorporating leadership training as a part of graduate medical education. However, there is considerable lack of agreement regarding how to facilitate acquisition...
Thu Jun 04, 2020 13:23
Related ArticlesInsulinemic Potential of Lifestyle Is Inversely Associated with Leukocyte Mitochondrial DNA Copy Number in US White Adults. J Nutr. 2020 Jun 03;: Authors: Yang K, Forman MR, Monahan PO, Graham BH, Chan AT, Zhang X, De Vivo I, Giovannucci EL, Tabung FK, Nan H Abstract BACKGROUND: Poor lifestyles have been linked to insulin insensitivity/hyperinsulinemia, which may contribute to downstream changes such as inflammation and oxidative damage...
Thu Jun 04, 2020 17:24
Related ArticlesThe Type and Amount of Dietary Fat Affect Plasma Factor VIIc, Fibrinogen, and PAI-1 in Healthy Individuals and Individuals at High Cardiovascular Disease Risk: 2 Randomized Controlled Trials. J Nutr. 2020 Jun 03;: Authors: Kris-Etherton PM, Stewart PW, Ginsberg HN, Tracy RP, Lefevre M, Elmer PJ, Berglund L, Ershow AG, Pearson TA, Ramakrishnan R, Holleran SF, Dennis BH, Champagne CM, Karmally W, DELTA Investigators Abstract BACKGROUND:...
Thu Jun 04, 2020 17:24
Related ArticlesAn Afternoon Hummus Snack Affects Diet Quality, Appetite, and Glycemic Control in Healthy Adults. J Nutr. 2020 Jun 03;: Authors: Reister EJ, Leidy HJ Abstract BACKGROUND: Snacking continues to be a major component in the dietary patterns of most Americans despite conflicting evidence surrounding snacking healthfulness. Low-sugar, highly nutritive snacks, such as hummus, can lead to improvements in diet quality, appetite, and glycemic...
Thu Jun 04, 2020 13:22
Related ArticlesBiosynthesis of antioxidative enzymes and polyphenolics content in calli cultures of Prunella vulgaris L. in response to auxins and cytokinins. Artif Cells Nanomed Biotechnol. 2020 Dec;48(1):893-902 Authors: Fazal H, Abbasi BH, Ahmad N, Noureen B, Shah J, Ma D, Chuanliang L, Akbar F, Uddin MN, Khan H, Ali M Abstract Prunella vulgaris L. is one of the therapeutic herbs containing various polyphenolics, which is used for multiple medicinal...
Thu Jun 04, 2020 13:13
Related ArticlesCirculating myeloid-derived suppressor cells facilitate invasion of thyroid cancer cells by repressing miR-486-3p. J Clin Endocrinol Metab. 2020 Jun 03;: Authors: Chen L, Xiong L, Hong S, Li J, Huo Z, Li Y, Chen S, Zhang Q, Zhao R, Gingold JA, Zhu X, Lv W, Li Y, Yu S, Xiao H Abstract BACKGROUND: Myeloid-derived suppressor cells (MDSCs) have become increasingly recognized as facilitators of tumor development. However, the role of MDSCs...
Thu Jun 04, 2020 14:46
Related ArticlesEvaluation of pathologic staging using number of nodes in p16-negative head and neck cancer. Oral Oncol. 2020 May 31;108:104800 Authors: Farquhar DR, Coniglio AJ, Masood MM, Lenze N, Brennan P, Anantharaman D, Abedi-Ardekani B, Zanation AM, Weissler MC, Olshan AF, Sheth S, Hackman TG Abstract OBJECTIVES: The 8th edition AJCC staging guidelines for head and neck squamous cell carcinoma (HNSCC) recently introduced pathologic staging...
Thu Jun 04, 2020 14:46
Related ArticlesHow to perform a nasopharyngeal swab - an otolaryngology perspective. Am J Med. 2020 May 31;: Authors: Kaufman AC, Brewster R, Rajasekaran K PMID: 32492374 [PubMed - as supplied by publisher]
Thu Jun 04, 2020 14:46
Related ArticlesPersistence and clearance of oral human papillomavirus infections: a prospective population-based cohort study. J Med Virol. 2020 Jun 03;: Authors: Wong MC, Vlantis AC, Liang M, Wong PY, Ho WC, Boon SS, Leung C, Chan PK, Chen Z Abstract OBJECTIVE: This study aimed to evaluate the incidence of and factors associated with persistence and clearance of oral HPV infections. METHOD: A prospective cohort study invited 458 subjects...
Thu Jun 04, 2020 14:46
Related ArticlesSupraclavicular Artery Island Flap: Critical Appraisal and Comparison to Alternate Reconstruction. Laryngoscope. 2020 Jun 03;: Authors: Kokot N, Kim JH, West JD, Zhang P Abstract OBJECTIVES/HYPOTHESIS: The supraclavicular artery island (SAI) flap may be a good option for selected head and neck reconstruction due to its reliability, ease of harvest, and favorable color match. The objective of this study was to examine the rates of...
Thu Jun 04, 2020 14:46
Related ArticlesAssociation Between Orthonasal Olfaction and Chemosensory Perception in Patients With Smell Loss. Laryngoscope. 2020 Jun 03;: Authors: Liu DT, Besser G, Prem B, Sharma G, Koenighofer M, Renner B, Mueller CA Abstract OBJECTIVES: Self-ratings seem to be the most effortless strategy for assessment of patients' chemical senses. Notably, although flavor perception strongly relies on olfaction, the relationship between self-reported flavor...
Thu Jun 04, 2020 14:46
Related ArticlesRisk factors for aggressive recurrent respiratory papillomatosis in Chinese juvenile patients. Acta Otolaryngol. 2020 Jun 03;:1-6 Authors: Xi Y, Wang H, Wang W, Wang X, Zhang J, Zhao J, Wang G, Gui J, Ni X Abstract Background: Aggressive juvenile-onset recurrent respiratory papillomatosis (JORRP) threatens patient lives if not receives immediate surgical intervene. Even with surgical intervene, complete remission of this disease is...
Thu Jun 04, 2020 14:46
Related ArticlesClinical characteristics of subglottic cancer: emphasis on therapeutic management strategies for stage II subglottic cancer. Acta Otolaryngol. 2020 Jun 03;:1-6 Authors: Komatsubara Y, Tachibana T, Orita Y, Makino T, Kuroda K, Naoi Y, Kataoka Y, Sato Y, Kariya S, Nishizaki K Abstract Background: Subglottic cancer (SGC) is extremely rare, as most laryngeal cancers are localized to the glottic region. Accordingly, the clinical characteristics...
Thu Jun 04, 2020 14:46
Related ArticlesCOVID-19: how it can look on the skin. Clinical and pathological features in twenty COVID-19 patients observed in Bologna, northeastern Italy. J Eur Acad Dermatol Venereol. 2020 Jun 03;: Authors: Gaspari V, Neri I, Misciali C, Patrizi A Abstract Global public health is currently dealing with the explosive spread of the novel Coronavirus disease 2019 (COVID-19) [1]. This new type of viral pneumonia, spread from its first focus in Wuhan...
Thu Jun 04, 2020 14:46
Related ArticlesThe issue of recurrently positive patients who recovered from COVID-19 according to the current discharge criteria: investigation of patients from multiple medical institutions in Wuhan, China. J Infect Dis. 2020 Jun 03;: Authors: Zou Y, Wang BR, Sun L, Xu S, Kong YG, Shen LJ, Liang GT, Chen SM Abstract The current discharge criteria for COVID-19 require that patients have two consecutive negative results for RT-PCR detection....
Thu Jun 04, 2020 14:46
Related ArticlesNurse Navigator: development of a program for Brazil. Rev Lat Am Enfermagem. 2020;28:e3275 Authors: Pautasso FF, Lobo TC, Flores CD, Caregnato RCA Abstract OBJECTIVE: to develop a Navigation Program for cancer patients, based on the model proposed by The GW Cancer Institute at George Washington University, adapted to the reality of a Brazilian High Complexity Center in Oncology. METHOD: a convergent care research applied...
Thu Jun 04, 2020 14:46
Related ArticlesCosts and outcomes of phacoemulsification for cataracts performed by residents. Arq Bras Oftalmol. 2020 Jun;83(3):209-214 Authors: Saad Filho R, Moreto R, Nakaghi RO, Haddad W, Coelho RP, Messias A Abstract PURPOSE: To describe costs and outcomes of phacoemulsification for cataracts performed by ophthalmology residents. METHODS: We obtained medical records from patients operated on in 2011 by third year residents (R3) using...
Thu Jun 04, 2020 14:46
Related ArticlesCoronavirus and the eye: what is relevant so far? Arq Bras Oftalmol. 2020 Jun;83(3):V-VI Authors: Lauande R, Paula JS PMID: 32490974 [PubMed - as supplied by publisher]
Thu Jun 04, 2020 14:46
Related ArticlesTopical mitomycin in endoscopic-assisted probing for the treatment of congenital nasolacrimal duct obstruction in older children. Arq Bras Oftalmol. 2020 Jun;83(3):229-235 Authors: Galindo-Ferreiro A, Khandekar R, Akaishi PM, Cruz AAV, Galvez-Ruiz A, Dolmetsch A, Schellini SA Abstract PURPOSE: Mitomycin C has been used in ophthalmic surgery to mitigate postoperative scarring. However, the outcomes of endoscopic-assisted probing for...
Thu Jun 04, 2020 14:46
Related ArticlesPembrolizumab given concomitantly with chemoradiation and as maintenance therapy for locally advanced head and neck squamous cell carcinoma: KEYNOTE-412. Future Oncol. 2020 Jun 03;: Authors: Machiels JP, Tao Y, Burtness B, Tahara M, Licitra L, Rischin D, Waldron J, Simon C, Gregoire V, Harrington K, Alves GV, Figueiredo Lima IP, Pointreau Y, M Hughes BG, Aksoy S, Hetnal M, Ge JY, Brown H, Cheng J, Bidadi B, Siu LL Abstract Current...
Thu Jun 04, 2020 13:12
Related ArticlesMagnetic foreign bodies in the hypopharynx: Usefulness of video laryngoscopy. Pediatr Int. 2020 Jun 03;: Authors: Suzuki J, Koizumi S, Endo T, Hemmi T, Katori Y PMID: 32490584 [PubMed - as supplied by publisher]
Thu Jun 04, 2020 13:12
Related ArticlesDetecting head and neck squamous carcinoma using a portable handheld electronic nose. Head Neck. 2020 Jun 03;: Authors: van de Goor RMGE, van Hooren MRA, Henatsch D, Kremer B, Kross KW Abstract INTRODUCTION: Detecting volatile organic compounds in exhaled breath enables the diagnosis of cancer. We investigated whether a handheld version of an electronic nose is able to discriminate between patients with head and neck squamous cell...
Thu Jun 04, 2020 13:12
Related ArticlesHow the World's Children Hear: A Narrative Review of School Hearing Screening Programs Globally. OTO Open. 2020 Apr-Jun;4(2):2473974X20923580 Authors: Yong M, Panth N, McMahon CM, Thorne PR, Emmett SD Abstract Objective: School hearing screening may mitigate the effects of childhood hearing loss through early identification and intervention. This study provides an overview of existing school hearing screening programs around the world,...
Thu Jun 04, 2020 13:12
Related ArticlesRecent trends in airway management. F1000Res. 2020;9: Authors: Abdelmalak BB, Doyle DJ Abstract Clinical airway management continues to advance at a fast pace. To help update busy anesthesiologists, this abbreviated review summarizes notable airway management advances over the past few years. We briefly discuss advances in video laryngoscopy, in flexible intubation scopes, in jet ventilation, and in extracorporeal membrane oxygenation...
Thu Jun 04, 2020 13:12
Related ArticlesIdentification and validation of an alternative splicing-based prognostic signature for head and neck squamous cell carcinoma. J Cancer. 2020;11(15):4571-4580 Authors: Zhao X, Si S, Li X, Sun W, Cui L Abstract Increasing evidence has demonstrated that changes in alternative splicing (AS) events are closely associated with the initiation and progression of cancer. However, the concrete role of AS in tumorigenesis of head and neck squamous...
Thu Jun 04, 2020 13:12
Related ArticlesChanges in serum inflammatory factor interleukin-6 levels and pathology of carotid vessel walls of rats with chronic periodontitis and diabetes mellitus after the periodontal intervention. Saudi J Biol Sci. 2020 Jun;27(6):1679-1684 Authors: Chen D, Zhong L, Li Y, He R, Ding C, Chen X, Lian W Abstract Objective: The effects of the periodontal intervention on rats with type-II diabetes mellitus (T2DM) and chronic periodontitis (CP)...
Thu Jun 04, 2020 13:12
Related ArticlesOrganizational guidance for the care of patients with head-and-neck cancer in Ontario. Curr Oncol. 2020 Apr;27(2):e115-e122 Authors: Irish J, Kim J, Waldron J, Wei AC, Winquist E, Yoo J, Boasie A, Brouwers M, Meertens E, McNair S, Walker-Dilks C, Expert Panel on Organizational Guidance for the Care of Patients with Head and Neck Cancer in Ontario Abstract Background: At the request of the Head and Neck Cancers Advisory Committee of...
Thu Jun 04, 2020 13:12
Related ArticlesRadiotherapy side effects: integrating a survivorship clinical lens to better serve patients. Curr Oncol. 2020 Apr;27(2):107-112 Authors: Dilalla V, Chaput G, Williams T, Sultanem K Abstract The Canadian Cancer Society estimated that 220,400 new cases of cancer would be diagnosed in 2019. Of the affected patients, more than 60% will survive for 5 years or longer after their cancer diagnosis. Furthermore, nearly 40% will receive at...
Thu Jun 04, 2020 13:12
Related ArticlesTrends and clinicopathological characteristics of oral squamous cell carcinomas reported at a tertiary cancer hospital in Nepal during 1999 to 2009. Clin Exp Dent Res. 2020 Jan 12;: Authors: Gajurel R, Gautam DK, Pun CB, Dhakal HP, Petrovski BÃ, Costea DE, Sapkota D Abstract OBJECTIVE: Reliable data describing the trends and clinicopathological characteristics of oral squamous cell carcinoma (OSCC) in the Nepalese population are very...
Thu Jun 04, 2020 13:12
Related ArticlesNegative illness perceptions are related to poorer health-related quality of life among thyroid cancer survivors: Results from the PROFILES registry. Head Neck. 2020 Jun 03;: Authors: Schoormans D, Wijnberg L, Haak H, Husson O, Mols F Abstract BACKGROUND: Differentiated thyroid cancer (DTC) reports a poorer health-related quality of life (HRQoL) than a norm population. Patients' illness perceptions are modifiable and known associates...
Thu Jun 04, 2020 13:12
Related ArticlesProposal to extend the PROMIS® item bank v2.0 'Ability to Participate in Social Roles and Activities': item generation and content validity. Qual Life Res. 2020 Jun 02;: Authors: van Leeuwen LM, Tamminga SJ, Ravinskaya M, de Wind A, Hahn EA, Terwee CB, Beckerman H, Boezeman EJ, Hoving JL, Huysmans MA, Nieuwenhuijsen K, de Boer AGEM, van der Beek AJ Abstract PURPOSE: Previous research indicated that the Patient-Reported Outcomes Measurement...
Thu Jun 04, 2020 13:12
Related ArticlesHow Can We Predict the Recovery from Pitch Lowering After Thyroidectomy? World J Surg. 2020 Jun 02;: Authors: Kim SY, Park JO, Bae JS, Lee SH, Hwang YS, Shim MR, Park YH, Sun DI Abstract BACKGROUND: Some of patients are suffered from pitch lowering of voice after thyroidectomy. We sought to identify factors predictive of a recovery from lowered pitch voice after thyroid surgery. METHODS: We retrospectively reviewed the records...
Thu Jun 04, 2020 13:12
Related ArticlesPapillary Thyroid Cancer-Aggressive Variants and Impact on Management: A Narrative Review. Adv Ther. 2020 Jun 01;: Authors: Coca-Pelaz A, Shah JP, Hernandez-Prera JC, Ghossein RA, Rodrigo JP, Hartl DM, Olsen KD, Shaha AR, Zafereo M, Suarez C, Nixon IJ, Randolph GW, Mäkitie AA, Kowalski LP, Vander Poorten V, Sanabria A, Guntinas-Lichius O, Simo R, Zbären P, Angelos P, Khafif A, Rinaldo A, Ferlito A Abstract INTRODUCTION: Aggressive...
Thu Jun 04, 2020 13:12
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