Antibiotics, Vol. 9, Pages 326: Rifabutin Use in Staphylococcus Biofilm Infections: A Case Series Antibiotics doi: 10.3390/antibiotics9060326 Authors: James B. Doub Emily L. Heil Afua Ntem-Mensah Renaldo Neeley Patrick R. Ching This is a case series of 10 patients who had staphylococcal biofilm infections that were treated with adjuvant rifabutin therapy instead of rifampin therapy. In these cases, rifampin was contraindicated secondary to drug–drug interactions...
Sat Jun 13, 2020 03:00
Antibiotics, Vol. 9, Pages 325: The Revaluation of Plant-Derived Terpenes to Fight Antibiotic-Resistant Infections Antibiotics doi: 10.3390/antibiotics9060325 Authors: Cappiello Loffredo Del Plato Cammarone Casciaro Quaglio Mangoni Botta Ghirga The discovery of antibiotics has revolutionized the medicine and treatment of microbial infections. However, the current scenario has highlighted the difficulties in marketing new antibiotics and an exponential...
Sat Jun 13, 2020 03:00
Antibiotics, Vol. 9, Pages 324: Prevalence of Multi-Resistant Microorganisms and Antibiotic Stewardship among Hospitalized Patients Living in Residential Care Homes in Spain: A Cross-Sectional Study Antibiotics doi: 10.3390/antibiotics9060324 Authors: Mario Rivera-Izquierdo Alberto Benavente-Fernández Jairo López-Gómez Antonio Jesús Láinez-Ramos-Bossini Marta Rodríguez-Camacho María del Carmen Valero-Ubierna Luis Miguel Martín-delosReyes Eladio Jiménez-Mejías Elena...
Sat Jun 13, 2020 03:00
Antibiotics, Vol. 9, Pages 323: Acacia senegal Extract Rejuvenates the Activity of Phenicols on Selected Enterobacteriaceae Multi Drug Resistant Strains Antibiotics doi: 10.3390/antibiotics9060323 Authors: Magnini Hilou Millogo-Koné Pagès Davin-Regli This study reported the phytochemical composition of two hydroethanolic extracts of Acacia senegal and Acacia seyal trees from Burkina Faso and their activities, alone or in combination with selected antibiotics, against...
Sat Jun 13, 2020 03:00
Antibiotics, Vol. 9, Pages 322: Retraction: Qian, W., et al. In Vitro Antibacterial Activity and Mechanism of Vanillic Acid against Carbapenem-Resistant Enterobacter cloacae. Antibiotics 2019, 8, 220 Antibiotics doi: 10.3390/antibiotics9060322 Authors: Antibiotics Editorial Office The authors have been made aware that two figures were published in two papers: Figure 5A in paper [...]
Fri Jun 12, 2020 03:00
Antioxidants, Vol. 9, Pages 523: Non-Esterified Fatty Acid-Induced Reactive Oxygen Species Mediated Granulosa Cells Apoptosis Is Regulated by Nrf2/p53 Signaling Pathway Antioxidants doi: 10.3390/antiox9060523 Authors: Yiru Wang Chengmin Li Julang Li Genlin Wang Lian Li Negative energy balance (NEB) during the perinatal period can affect dairy cow follicular development and reduce the fecundity. Non-esterified fatty acid (NEFA) concentration is elevated during NEB, and is...
Sun Jun 14, 2020 03:00
Antioxidants, Vol. 9, Pages 522: The Impact of Acetyl-CoA and Aspartate Shortages on the N-Acetylaspartate Level in Different Models of Cholinergic Neurons Antioxidants doi: 10.3390/antiox9060522 Authors: Marlena Zyśk Monika Sakowicz-Burkiewicz Piotr Pikul Robert Kowalski Anna Michno Tadeusz Pawełczyk N-acetylaspartate is produced by neuronal aspartate N-acetyltransferase (NAT8L) from acetyl-CoA and aspartate. In cholinergic neurons, acetyl-CoA is also utilized in the...
Sat Jun 13, 2020 03:00
Antioxidants, Vol. 9, Pages 521: The Integrative Role of Sulforaphane in Preventing Inflammation, Oxidative Stress and Fatigue: A Review of a Potential Protective Phytochemical Antioxidants doi: 10.3390/antiox9060521 Authors: Ruheea Taskin Ruhee Katsuhiko Suzuki Cruciferous vegetables hold a myriad of bioactive molecules that are renowned for possessing unique medicinal benefits. Sulforaphane (SFN) is one of the potential nutraceuticals contained within cruciferous vegetables that...
Sat Jun 13, 2020 03:00
Antioxidants, Vol. 9, Pages 519: Protoflavone-Chalcone Hybrids Exhibit Enhanced Antitumor Action through Modulating Redox Balance, Depolarizing the Mitochondrial Membrane, and Inhibiting ATR-Dependent Signaling Antioxidants doi: 10.3390/antiox9060519 Authors: Ahmed Dhahir Latif Tamás Jernei Ana Podolski-Renić Ching-Ying Kuo Máté Vágvölgyi Gábor Girst István Zupkó Sedef Develi Engin Ulukaya Hui-Chun Wang Milica Pešić Antal Csámpai Attila Hunyadi Hybrid...
Fri Jun 12, 2020 03:00
Antioxidants, Vol. 9, Pages 518: Nrf2 Activator PB125® as a Potential Therapeutic Agent against COVID-19 Antioxidants doi: 10.3390/antiox9060518 Authors: Joe M. McCord Brooks M. Hybertson Adela Cota-Gomez Kara P. Geraci Bifeng Gao Nrf2 is a transcription factor that regulates cellular redox balance and the expression of a wide array of genes involved in immunity and inflammation, including antiviral actions. Nrf2 activity declines with age, making the elderly more susceptible...
Fri Jun 12, 2020 03:00
Antioxidants, Vol. 9, Pages 517: Comparative Studies on Different Citrus Cultivars: A Revaluation of Waste Mandarin Components Antioxidants doi: 10.3390/antiox9060517 Authors: Giulia Costanzo Maria Rosaria Iesce Daniele Naviglio Martina Ciaravolo Ermenegilda Vitale Carmen Arena Peel, pulp and seed extracts of three mandarin varieties, namely Phlegraean mandarin (Citrus reticulata), Kumquat (Citrus japonica), and Clementine (Citrus clementina) were compared and characterised...
Fri Jun 12, 2020 03:00
Antioxidants, Vol. 9, Pages 520: Eicosanoids and Oxidative Stress in Diabetic Retinopathy Antioxidants doi: 10.3390/antiox9060520 Authors: Mong-Heng Wang George Hsiao Mohamed Al-Shabrawey Oxidative stress is an important factor to cause the pathogenesis of diabetic retinopathy (DR) because the retina has high vascularization and long-time light exposition. Cyclooxygenase (COX), lipoxygenase (LOX), and cytochrome P450 (CYP) enzymes can convert arachidonic acid (AA) into eicosanoids,...
Fri Jun 12, 2020 03:00
Atmosphere, Vol. 11, Pages 631: Diurnal Characteristics of Gravity Waves over the Tibetan Plateau in 2015 Summer Using 10-km Downscaled Simulations from WRF-EnKF Regional Reanalysis Atmosphere doi: 10.3390/atmos11060631 Authors: Qian Zhang Wei He Lu Diurnal variations of gravity waves over the Tibetan Plateau (TP) in summer 2015 were investigated based on high-resolution downscaled simulations from WRF-EnKF (Weather Research and Forecasting model and an ensemble Kalman...
Sun Jun 14, 2020 03:00
Atmosphere, Vol. 11, Pages 630: Insignificant Impact of the “Stay-At-Home” Order on Ambient Air Quality in the Memphis Metropolitan Area, U.S.A. Atmosphere doi: 10.3390/atmos11060630 Authors: Jia Fu Bartelli Smith The lockdowns due to the COVID-19 pandemic have been reported to reduce ambient air pollution in many cities globally. This study aims to examine whether air pollution dropped in Memphis, a typical U.S. metropolitan city and transportation hub, during the lockdown...
Sun Jun 14, 2020 03:00
Atmosphere, Vol. 11, Pages 629: Urban CO2 Budget: Spatial and Seasonal Variability of CO2 Emissions in Krakow, Poland Atmosphere doi: 10.3390/atmos11060629 Authors: Alina Jasek-Kamińska Mirosław Zimnoch Przemysław Wachniew Kazimierz Różański Krakow, with an area of 327 km2 and over 750,000 inhabitants, is one of the largest cities in Poland. Within the administrative city borders several anthropogenic CO2 source types are located, including car traffic, household coal and natural...
Sun Jun 14, 2020 03:00
Atmosphere, Vol. 11, Pages 626: Observations of Turbulent Heat Fluxes Variability in a Semiarid Coastal Lagoon (Gulf of California) Atmosphere doi: 10.3390/atmos11060626 Authors: Benítez-Valenzuela Sanchez-Mejia Despite the critical role latent (LE) and sensible (H) heat play in turbulent processes and heat exchange in the water–air interface, there is a lack of studies of turbulent fluxes over the surface in semiarid regions. We collected continuous measurements of net...
Sat Jun 13, 2020 03:00
Atmosphere, Vol. 11, Pages 627: Face Temperature as an Indicator of Thermal Stress in Outdoor Work Environments Atmosphere doi: 10.3390/atmos11060627 Authors: Hastings Kim Brown The frequency and duration of heatwaves are steadily increasing as climate change becomes more serious. These changes particularly endanger the health of those who must work outdoors in hot environments. This study introduces a novel approach to monitor the heat-health of airport outdoor workers using...
Sat Jun 13, 2020 03:00
Atmosphere, Vol. 11, Pages 628: A Comparison of Northern Hemisphere Atmospheric Rivers Detected by a New Image-Processing Based Method and Magnitude-Thresholding Based Methods Atmosphere doi: 10.3390/atmos11060628 Authors: Guangzhi Xu Xiaohui Ma Ping Chang Lin Wang A majority of the existing atmospheric rivers (ARs) detection methods is based on magnitude thresholding on either the integrated water vapor (IWV) or integrated vapor transport (IVT). One disadvantage of such an...
Sat Jun 13, 2020 03:00
Atmosphere, Vol. 11, Pages 625: High Resolution Air Quality Forecasting Over Prague within the URBI PRAGENSI Project: Model Performance During the Winter Period and the Effect of Urban Parameterization on PM Atmosphere doi: 10.3390/atmos11060625 Authors: Jana Ďoubalová Peter Huszár Kryštof Eben Nina Benešová Michal Belda Ondřej Vlček Jan Karlický Jan Geletič Tomáš Halenka The overall impact of urban environments on the atmosphere is the result of many different...
Fri Jun 12, 2020 03:00
Atmosphere, Vol. 11, Pages 624: Black Carbon: The Concentration and Sources Study at the Nam Co Lake, the Tibetan Plateau from 2015 to 2016 Atmosphere doi: 10.3390/atmos11060624 Authors: Feiteng Wang Xin Zhang Xiaoying Yue Mengyuan Song Guoshuai Zhang Jing Ming We measured black carbon (BC) with a seven-wavelength aethalometer (AE-31) at the Nam Co Lake (NCL), the hinterland of the Tibetan Plateau (TP) from May 2015 to April 2016. The daily average concentration of BC...
Fri Jun 12, 2020 03:00
Atmosphere, Vol. 11, Pages 622: Role of Wind Shear in the Decay of Convective Boundary Layers Atmosphere doi: 10.3390/atmos11060622 Authors: Seung-Bu Park Jong-Jin Baik Beom-Soon Han The role of wind shear in the decay of the convective boundary layer (CBL) is systematically investigated using a series of large-eddy simulations. Nine CBLs with weak, intermediate, and strong wind shear are simulated, and their decays after stopping surface heat flux are investigated. After the surface...
Fri Jun 12, 2020 03:00
Atmosphere, Vol. 11, Pages 623: Assessment of Meteorological Drought and Wet Conditions Using Two Drought Indices across KwaZulu-Natal Province, South Africa Atmosphere doi: 10.3390/atmos11060623 Authors: Ndlovu Demlie South Africa has been experiencing a series of droughts for the last few years, limiting the availability of water supply in reservoirs and impacting many sectors of the economy. These droughts have affected even the wetter eastern provinces including KwaZulu-Natal....
Fri Jun 12, 2020 03:00
Bioengineering, Vol. 7, Pages 57: Pseudopterosin and O-Methyltylophorinidine Suppress Cell Growth in a 3D Spheroid Co-Culture Model of Pancreatic Ductal Adenocarcinoma Bioengineering doi: 10.3390/bioengineering7020057 Authors: Bailu Xie Jan Hänsel Vanessa Mundorf Janina Betz Irene Reimche Mert Erkan Ibrahim Büdeyri Anne Gesell Russell G. Kerr Ni Putu Ariantari Haiqian Yu Peter Proksch Nicole Teusch Randall J. Mrsny Current therapies for treating...
Sun Jun 14, 2020 03:00
Bioengineering, Vol. 7, Pages 56: Modulation of the Microtubule Network for Optimization of Nanoparticle Dynamics for the Advancement of Cancer Nanomedicine Bioengineering doi: 10.3390/bioengineering7020056 Authors: Aaron Bannister Dushanthi Dissanayake Antonia Kowalewski Leah Cicon Kyle Bromma Devika B. Chithrani Nanoparticles (NPs) have shown promise in both radiotherapy and chemotherapy. NPs are mainly transported along cellular microtubules (MTs). Docetaxel (DTX) is...
Sun Jun 14, 2020 03:00
Biology, Vol. 9, Pages 123: Molecular Aggregation in Immune System Activation Studied by Dynamic Light Scattering Biology doi: 10.3390/biology9060123 Authors: Elena Velichko Sergey Makarov Elina Nepomnyashchaya Ge Dong Determination of the concentration and size of the circulating immune complexes in the blood is an essential part of diagnostics of immune diseases. In this work, we suggest using the dynamic light scattering method to determine the sizes of circulating immune...
Fri Jun 12, 2020 03:00
Biology, Vol. 9, Pages 125: Phosphoinositide Lipids in Ocular Tissues Biology doi: 10.3390/biology9060125 Authors: Ammaji Rajala Austin McCauley Richard S. Brush Khuong Nguyen Raju V.S. Rajala Inositol phospholipids play an important role in cell physiology. The inositol head groups are reversibly phosphorylated to produce seven distinct phosphorylated inositides, commonly referred to as phosphoinositides (PIs). These seven PIs are dynamically interconverted from one PI to...
Fri Jun 12, 2020 03:00
Biology, Vol. 9, Pages 126: STAT3 Pathway in Gastric Cancer: Signaling, Therapeutic Targeting and Future Prospects Biology doi: 10.3390/biology9060126 Authors: Milad Ashrafizadeh Ali Zarrabi Sima Orouei Vahideh Zarrin Ebrahim Rahmani Rahmani Moghadam Amirhossein Zabolian Shima Mohammadi Kiavash Hushmandi Yashar Gharehaghajlou Pooyan Makvandi Masoud Najafi Reza Mohammadinejad Molecular signaling pathways play a significant role in the regulation of biological...
Fri Jun 12, 2020 03:00
Biology, Vol. 9, Pages 124: Soluble Epoxide Hydrolase Inhibition in Liver Diseases: A Review of Current Research and Knowledge Gaps Biology doi: 10.3390/biology9060124 Authors: Jeffrey Warner Josiah Hardesty Kara Zirnheld Craig McClain Dennis Warner Irina Kirpich Emerging evidence suggests that soluble epoxide hydrolase (sEH) inhibition is a valuable therapeutic strategy for the treatment of numerous diseases, including those of the liver. sEH rapidly degrades cytochrome...
Fri Jun 12, 2020 03:00
Biology, Vol. 9, Pages 122: Revisiting the Impact of Neurodegenerative Proteins in Epilepsy: Focus on Alpha-Synuclein, Beta-Amyloid, and Tau Biology doi: 10.3390/biology9060122 Authors: Yam Nath Paudel Efthalia Angelopoulou Christina Piperi Iekhsan Othman Mohd. Farooq Shaikh Lack of disease-modifying therapy against epileptogenesis reflects the complexity of the disease pathogenesis as well as the high demand to explore novel treatment strategies. In the pursuit of developing...
Fri Jun 12, 2020 03:00
Biology, Vol. 9, Pages 121: Development of a Pulsatile Flow-Generating Circulatory Assist Device (K-Beat) For Use with Veno-Arterial Extracorporeal Membrane Oxygenation in a Pig Model Study Biology doi: 10.3390/biology9060121 Authors: Yutaka Fujii Nobuo Akamatsu Yasunori Yamasaki Kota Miki Masayuki Banno Kenta Minami Shuji Inamori Veno-arterial extracorporeal membrane oxygenation (V-A ECMO) preserves the life of heart failure patients by providing an adequate oxygen...
Fri Jun 12, 2020 03:00
Biomedicines, Vol. 8, Pages 158: Image Analysis of 3D Conjunctival Melanoma Cell Cultures Following Electrochemotherapy Biomedicines doi: 10.3390/biomedicines8060158 Authors: Fiorentzis Katopodis Kalirai Seitz Viestenz Coupland Three-dimensional (3D) cell cultures represent small avascular tumors in vitro and simulate some of the biological characteristics of solid tumors, enhancing the evaluation of anticancer drug efficacy. Automated image analysis can be used...
Sat Jun 13, 2020 03:00
Biomedicines, Vol. 8, Pages 159: Leucine Potentiates Glucose-mediated 18F-FDG Uptake in Brown Adipose Tissue via β-Adrenergic Activation Biomedicines doi: 10.3390/biomedicines8060159 Authors: Brenda Huska Sarah Niccoli Christopher P. Phenix Simon J. Lees Significant depots of brown adipose tissue (BAT) have been identified in many adult humans through positron emission tomography (PET), with the amount of BAT being inversely correlated with obesity. As dietary activation of...
Sat Jun 13, 2020 03:00
Biomimetics, Vol. 5, Pages 28: Lotus Effect and Friction: Does Nonsticky Mean Slippery? Biomimetics doi: 10.3390/biomimetics5020028 Authors: Md Syam Hasan Michael Nosonovsky Lotus-effect-based superhydrophobicity is one of the most celebrated applications of biomimetics in materials science. Due to a combination of controlled surface roughness (surface patterns) and low-surface energy coatings, superhydrophobic surfaces repel water and, to some extent, other liquids. However, many...
Fri Jun 12, 2020 03:00
Biomolecules, Vol. 10, Pages 904: NRF2 Regulation Processes as a Source of Potential Drug Targets against Neurodegenerative Diseases Biomolecules doi: 10.3390/biom10060904 Authors: Cores Piquero Villacampa León Menéndez NRF2 acts by controlling gene expression, being the master regulator of the Phase II antioxidant response, and also being key to the control of neuroinflammation. NRF2 activity is regulated at several levels, including protein degradation by the proteasome,...
Sun Jun 14, 2020 03:00
Biomolecules, Vol. 10, Pages 903: The Arg/N-Degron Pathway—A Potential Running Back in Fine-Tuning the Inflammatory Response? Biomolecules doi: 10.3390/biom10060903 Authors: Dominique Leboeuf Maxim Pyatkov Timofei S. Zatsepin Konstantin Piatkov Recognition of danger signals by a cell initiates a powerful cascade of events generally leading to inflammation. Inflammatory caspases and several other proteases become activated and subsequently cleave their target proinflammatory...
Sun Jun 14, 2020 03:00
Biomolecules, Vol. 10, Pages 902: EGFP Reporters for Direct and Sensitive Detection of Mutagenic Bypass of DNA Lesions Biomolecules doi: 10.3390/biom10060902 Authors: Rodriguez-Alvarez Kim Khobta The sustainment of replication and transcription of damaged DNA is essential for cell survival under genotoxic stress; however, the damage tolerance of these key cellular functions comes at the expense of fidelity. Thus, translesion DNA synthesis (TLS) over damaged nucleotides is a...
Sat Jun 13, 2020 03:00
Biomolecules, Vol. 10, Pages 901: Extracellular Vesicles miRNA Cargo for Microglia Polarization in Traumatic Brain Injury Biomolecules doi: 10.3390/biom10060901 Authors: Maria Antonietta Panaro Tarek Benameur Chiara Porro Traumatic brain injury (TBI) is one of the major causes of death and disability worldwide, and despite its high dissemination, effective pharmacotherapies are lacking. TBI can be divided into two phases: the instantaneous primary mechanical injury, which occurs...
Fri Jun 12, 2020 03:00
Biomolecules, Vol. 10, Pages 899: Bicyclic Boronates as Potent Inhibitors of AmpC, the Class C β-Lactamase from Escherichia coli Biomolecules doi: 10.3390/biom10060899 Authors: Pauline Lang Anete Parkova Thomas Leissing Karina Calvopiña Ricky Cain Alen Krajnc Tharindi Panduwawala Jules Philippe Colin Fishwick Peteris Trapencieris Malcolm Page Christopher Schofield Jürgen Brem Resistance to β-lactam antibacterials, importantly via production of β-lactamases,...
Fri Jun 12, 2020 03:00
Biomolecules, Vol. 10, Pages 900: Isolation, Purification, and Antimicrobial Characterization of Cannabidiolic Acid and Cannabidiol from Cannabis sativa L Biomolecules doi: 10.3390/biom10060900 Authors: Laura Daniela Martinenghi Rie Jønsson Torben Lund Håvard Jenssen The emergence of multi-drug resistant bacteria such as methicillin-resistant Staphylococcus aureus (MRSA) causes a major threat to public health due to its limited therapeutic options. There is an urgent need for...
Fri Jun 12, 2020 03:00
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