Κυριακή 14 Ιουνίου 2020


Quinazoline Based HSP90 Inhibitors: Synthesis, Modeling Study and ADME Calculations Towards Breast Cancer Targeting.
Related ArticlesQuinazoline Based HSP90 Inhibitors: Synthesis, Modeling Study and ADME Calculations Towards Breast Cancer Targeting. Bioorg Med Chem Lett. 2020 Aug 01;30(15):127281 Authors: El-Shafey HW, Gomaa RM, El-Messery SM, Goda FE Abstract A new 2-thioquinazolinones series was designed and synthesized as HSP90 inhibitors based on the structure of hit compound VII obtained by virtual screening approach. Their in vitro anti-proliferative activity...
pubmed: cell cycle arrest
Sat Jun 13, 2020 13:23
Cyperus articulatus L. (Cyperaceae) Rhizome Essential Oil Causes Cell Cycle Arrest in the G2/M Phase and Cell Death in HepG2 Cells and Inhibits the Development of Tumors in a Xenograft Model.
Related ArticlesCyperus articulatus L. (Cyperaceae) Rhizome Essential Oil Causes Cell Cycle Arrest in the G2/M Phase and Cell Death in HepG2 Cells and Inhibits the Development of Tumors in a Xenograft Model. Molecules. 2020 Jun 09;25(11): Authors: Nogueira ML, Lima EJSP, Adrião AAX, Fontes SS, Silva VR, Santos LS, Soares MBP, Dias RB, Rocha CAG, Costa EV, Silva FMAD, Vannier-Santos MA, Cardozo NMD, Koolen HHF, Bezerra DP Abstract Cyperus articulatus...
pubmed: cell cycle arrest
Sat Jun 13, 2020 13:23
SIRT7 Deacetylates STRAP to Regulate p53 Activity and Stability.
Related ArticlesSIRT7 Deacetylates STRAP to Regulate p53 Activity and Stability. Int J Mol Sci. 2020 Jun 09;21(11): Authors: Yu M, Shi X, Ren M, Liu L, Qi H, Zhang C, Zou J, Qiu X, Zhu WG, Zhang YE, Wang W, Luo J Abstract Serine-threonine kinase receptor-associated protein (STRAP) functions as a regulator of both TGF-β and p53 signaling that participates in the regulation of cell proliferation and cell death in response to various stresses. Here,...
pubmed: cell cycle arrest
Sat Jun 13, 2020 13:23
Current definition of acute kidney injury actually identifies a heterogenous group of patients with elevated serum creatinine and reduced urine output.
Related ArticlesCurrent definition of acute kidney injury actually identifies a heterogenous group of patients with elevated serum creatinine and reduced urine output. Crit Care. 2020 05 24;24(1):247 Authors: Chen Y PMID: 32448400 [PubMed - indexed for MEDLINE]
pubmed: cell cycle arrest
Sat Jun 13, 2020 13:23
Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I.
Related ArticlesAutophagy promotes immune evasion of pancreatic cancer by degrading MHC-I. Nature. 2020 05;581(7806):100-105 Authors: Yamamoto K, Venida A, Yano J, Biancur DE, Kakiuchi M, Gupta S, Sohn ASW, Mukhopadhyay S, Lin EY, Parker SJ, Banh RS, Paulo JA, Wen KW, Debnath J, Kim GE, Mancias JD, Fearon DT, Perera RM, Kimmelman AC Abstract Immune evasion is a major obstacle for cancer treatment. Common mechanisms of evasion include impaired antigen...
pubmed: cell cycle arrest
Sat Jun 13, 2020 13:23
Gadd45β promotes regeneration after injury through TGFβ-dependent restitution in experimental colitis.
Related ArticlesGadd45β promotes regeneration after injury through TGFβ-dependent restitution in experimental colitis. Exp Mol Med. 2019 10 30;51(10):1-14 Authors: Hwang JH, Kim TH, Kim YH, Noh JR, Choi DH, Kim KS, Lee EY, Kim BC, Kim MH, Kim H, Lee TG, Lee JS, Lee CH Abstract Dysregulated immune responses and impaired function in intestinal epithelial cells contribute to the pathogenesis of inflammatory bowel disease (IBD). Growth arrest and DNA damage-inducible...
pubmed: cell cycle arrest
Sat Jun 13, 2020 13:23
Dual effect of the broad spectrum kinase inhibitor midostaurin in acute and latent HIV-1 infection.
Related ArticlesDual effect of the broad spectrum kinase inhibitor midostaurin in acute and latent HIV-1 infection. Antiviral Res. 2019 08;168:18-27 Authors: Garcia-Vidal E, Badia R, Pujantell M, Castellví M, Felip E, Clotet B, Riveira-Muñoz E, Ballana E, Esté JA Abstract Midostaurin is a multi-kinase inhibitor with antineoplastic activity. We assessed the capacity of midostaurin to affect early and late steps of HIV-1 infection and to reactivate HIV-1...
pubmed: cell cycle arrest
Sat Jun 13, 2020 13:23
Cell cycle control by the target of rapamycin signalling pathway in plants.
Related ArticlesCell cycle control by the target of rapamycin signalling pathway in plants. J Exp Bot. 2019 04 15;70(8):2275-2284 Authors: Ahmad Z, Magyar Z, Bögre L, Papdi C Abstract Cells need to ensure a sufficient nutrient and energy supply before committing to proliferate. In response to positive mitogenic signals, such as light, sugar availability, and hormones, the target of rapamycin (TOR) signalling pathway promotes cell growth that connects...
pubmed: cell cycle arrest
Sat Jun 13, 2020 13:23
Increased invasive phenotype of CSF-1R expression in glioma cells via the ERK1/2 signaling pathway.
Related ArticlesIncreased invasive phenotype of CSF-1R expression in glioma cells via the ERK1/2 signaling pathway. Cancer Gene Ther. 2019 05;26(5-6):136-144 Authors: Sun L, Liang H, Yu W, Jin X Abstract Glioma is a common malignant tumor of the central nervous system (CNS) that has no effective treatment. In this study, we report that colony-stimulating factor-1 receptor (CSF-1R) is a key mediator of malignant features in glioma via modulation of the...
pubmed: cell cycle arrest
Sat Jun 13, 2020 13:23
Suppressing growth, migration, and invasion of human hepatocellular HepG2 cells by Catharanthus roseus‑silver nanoparticles.
Related ArticlesSuppressing growth, migration, and invasion of human hepatocellular HepG2 cells by Catharanthus roseus‑silver nanoparticles. Toxicol In Vitro. 2020 Jun 08;:104910 Authors: Azhar NAB, Ghozali SZ, Bakar SAA, Lim V, Ahmad NH Abstract Application of silver nanoparticles serves as a new approach in cancer treatment due to its unique features. Biosynthesis of silver nanoparticles using plant is advantageous since they are easily accessible,...
pubmed: cell cycle arrest
Fri Jun 12, 2020 14:35
Dihydroorotate Dehydrogenase Inhibitors Promote Cell Cycle Arrest and Disrupt Mitochondria Bioenergetics in Ramos Cells.
Related ArticlesDihydroorotate Dehydrogenase Inhibitors Promote Cell Cycle Arrest and Disrupt Mitochondria Bioenergetics in Ramos Cells. Curr Pharm Biotechnol. 2020 Jun 11;: Authors: Kadir MFA, Othman S, Nellore K Abstract BACKGROUND: The re-emerging of targeting dihydroorotate dehydrogenase (DHODH) in cancer treatment particularly acute myelogenous leukemia (AML) have corroborated the substantial role of DHODH in cancer and fascinated the attention...
pubmed: cell cycle arrest
Fri Jun 12, 2020 14:35
The triphenyltin carboxylate derivative triphenylstannyl 2-(benzylcarbamoyl)benzoate impedes prostate cancer progression via modulation of Akt/FOXO3a signaling.
Related ArticlesThe triphenyltin carboxylate derivative triphenylstannyl 2-(benzylcarbamoyl)benzoate impedes prostate cancer progression via modulation of Akt/FOXO3a signaling. Toxicol Appl Pharmacol. 2020 Jun 07;:115091 Authors: Waseem D, Khan GM, Haq IU, Rashid U, Syed DN Abstract Prostate cancer (PCa) incidence is surging in United States and other parts of the world. Synthetic and natural compounds have been explored as potential modulators of...
pubmed: cell cycle arrest
Fri Jun 12, 2020 14:35
LINC02163 promotes colorectal cancer progression via miR-511-3p/AKT3 axis.
Related ArticlesLINC02163 promotes colorectal cancer progression via miR-511-3p/AKT3 axis. Artif Cells Nanomed Biotechnol. 2020 Dec;48(1):961-968 Authors: Ma J, Zhang L, Shang A, Song H, Huo J, Zhang M, Jiang L Abstract Long non-coding RNAs and microRNAs are functional regulators in tumour progression. Herein, we revealed the level LINC02163 was up-regulated in CRC tissues and cell lines, and the expression of LINC02163 negatively correlated with...
pubmed: cell cycle arrest
Fri Jun 12, 2020 14:35
Silence of FOXD2-AS1 inhibited the proliferation and invasion of esophagus cells by regulating miR-145-5p/CDK6 axis.
Related ArticlesSilence of FOXD2-AS1 inhibited the proliferation and invasion of esophagus cells by regulating miR-145-5p/CDK6 axis. Histol Histopathol. 2020 Jun 11;:18232 Authors: Shi W, Gao Z, Song J, Wang W Abstract This study aimed to investigate the function of long non-coding RNA FOXD2 adjacent opposite strand RNA 1 (lncRNA FOXD2-AS1) during the progression of esophagus cancer (EC) and explore its underlying molecular mechanisms. The level...
pubmed: cell cycle arrest
Fri Jun 12, 2020 13:36
Pine needle hexane extract promote cell cycle arrest and premature senescence via p27KIP1 upregulation gastric cancer cells.
Related ArticlesPine needle hexane extract promote cell cycle arrest and premature senescence via p27KIP1 upregulation gastric cancer cells. Food Sci Biotechnol. 2020 Jun;29(6):845-853 Authors: Kim W, Park C, Park J, Cheong H, Kim SJ Abstract Pinus densiflora sieb. et zucc.(pine needle) is a traditional medicine used in several East Asian countries. However, the efficacy of pine needle has rarely been reported. In this study showed that the anti-proliferative...
pubmed: cell cycle arrest
Fri Jun 12, 2020 13:36
KLF13 suppresses the proliferation and growth of colorectal cancer cells through transcriptionally inhibiting HMGCS1-mediated cholesterol biosynthesis.
Related ArticlesKLF13 suppresses the proliferation and growth of colorectal cancer cells through transcriptionally inhibiting HMGCS1-mediated cholesterol biosynthesis. Cell Biosci. 2020;10:76 Authors: Yao W, Jiao Y, Zhou Y, Luo X Abstract Background: Colorectal cancer (CRC) is the fourth most deadly malignancy throughout the world. Extensive studies have shown that Krüppel-like factors (KLFs) play essential roles in cancer development. However, the...
pubmed: cell cycle arrest
Fri Jun 12, 2020 13:36
Pyrimethamine Elicits Antitumor Effects on Prostate Cancer by Inhibiting the p38-NF-κB Pathway.
Related ArticlesPyrimethamine Elicits Antitumor Effects on Prostate Cancer by Inhibiting the p38-NF-κB Pathway. Front Pharmacol. 2020;11:758 Authors: Zhou X, Zhang J, Hu X, He P, Guo J, Li J, Lan T, Liu J, Peng L, Li H Abstract Since incurable castration-resistant prostate cancer (CRPC) inevitably develops following treatment with androgen deprivation therapy, there is an urgent need to devise new therapeutic strategies to treat this cancer. Pyrimethamine,...
pubmed: cell cycle arrest
Fri Jun 12, 2020 13:36
Circ_0000517 Contributes to Hepatocellular Carcinoma Progression by Upregulating TXNDC5 via Sponging miR-1296-5p.
Related ArticlesCirc_0000517 Contributes to Hepatocellular Carcinoma Progression by Upregulating TXNDC5 via Sponging miR-1296-5p. Cancer Manag Res. 2020;12:3457-3468 Authors: Zang H, Li Y, Zhang X, Huang G Abstract Background: Circular RNAs (circRNAs) function as essential regulators in diverse human cancers, including hepatocellular carcinoma (HCC). However, the function of circ_0000517 in HCC was unknown. We aimed to explore the roles and mechanisms...
pubmed: cell cycle arrest
Fri Jun 12, 2020 13:36
Genome-Wide Analysis Identifies NURR1-Controlled Network of New Synapse Formation and Cell Cycle Arrest in Human Neural Stem Cells.
Related ArticlesGenome-Wide Analysis Identifies NURR1-Controlled Network of New Synapse Formation and Cell Cycle Arrest in Human Neural Stem Cells. Mol Cells. 2020 Jun 10;: Authors: Kim SM, Cho SY, Kim MW, Roh SR, Shin HS, Suh YH, Geum D, Lee MA Abstract Nuclear receptor-related 1 (Nurr1) protein has been identified as an obligatory transcription factor in midbrain dopaminergic neurogenesis, but the global set of human NURR1 target genes remains...
pubmed: cell cycle arrest
Fri Jun 12, 2020 13:36
The local hypothalamic-pituitary-adrenal axis in cultured human dermal papilla cells.
Related ArticlesThe local hypothalamic-pituitary-adrenal axis in cultured human dermal papilla cells. BMC Mol Cell Biol. 2020 Jun 10;21(1):42 Authors: Lee EY, Nam YJ, Kang S, Choi EJ, Han I, Kim J, Kim DH, An JH, Lee S, Lee MH, Chung JH Abstract BACKGROUND: Stress is an important cause of skin disease, including hair loss. The hormonal response to stress is due to the HPA axis, which comprises hormones such as corticotropin releasing factor (CRF),...
pubmed: cell cycle arrest
Fri Jun 12, 2020 13:36
Novel [(N-alkyl-3-indolylmethylene)hydrazono]oxindoles arrest cell cycle and induce cell apoptosis by inhibiting CDK2 and Bcl-2: synthesis, biological evaluation and in silico studies.
Related ArticlesNovel [(N-alkyl-3-indolylmethylene)hydrazono]oxindoles arrest cell cycle and induce cell apoptosis by inhibiting CDK2 and Bcl-2: synthesis, biological evaluation and in silico studies. J Enzyme Inhib Med Chem. 2020 Dec;35(1):1300-1309 Authors: Al-Warhi T, Abo-Ashour MF, Almahli H, Alotaibi OJ, Al-Sanea MM, Al-Ansary GH, Ahmed HY, Elaasser MM, Eldehna WM, Abdel-Aziz HA Abstract As a continuation for our previous work, a novel set of...
pubmed: cell cycle arrest
Fri Jun 12, 2020 13:36
Paclitaxel inhibits transforming growth factor-β-increased urokinase-type plasminogen activator expression through p38 MAPK and RAW 264.7 macrophage migration.
Related ArticlesPaclitaxel inhibits transforming growth factor-β-increased urokinase-type plasminogen activator expression through p38 MAPK and RAW 264.7 macrophage migration. J BUON. 2020 Mar-Apr;25(2):1257-1265 Authors: Mojsilovic S, Tosic M, Mojsilovic S, Zivanovic M, Bjelica S, Srdic Rajic T, F Santibanez J Abstract PURPOSE: Transforming growth factor-β (TGF-β) induces alternative macrophage activation that favors tumor progression and immunosuppression....
pubmed: cell cycle arrest
Fri Jun 12, 2020 13:36
Anticancer effects of rosmarinic acid in human oral cancer cells is mediated via endoplasmic reticulum stress, apoptosis, G2/M cell cycle arrest and inhibition of cell migration.
Related ArticlesAnticancer effects of rosmarinic acid in human oral cancer cells is mediated via endoplasmic reticulum stress, apoptosis, G2/M cell cycle arrest and inhibition of cell migration. J BUON. 2020 Mar-Apr;25(2):1245-1250 Authors: Luo Y, Ma Z, Xu X, Qi H, Cheng Z, Chen L Abstract PURPOSE: This investigation was undertaken to infer the anticancer effects of rosmarinic acid against human oral cancer cells. METHODS: Normal hTRET-OME...
pubmed: cell cycle arrest
Fri Jun 12, 2020 13:36
Anticancer effects of Mahanimbine alkaloid on the human bladder cancer cells are due to the induction of G0/G1 cell cycle arrest, apoptosis and autophagy.
Related ArticlesAnticancer effects of Mahanimbine alkaloid on the human bladder cancer cells are due to the induction of G0/G1 cell cycle arrest, apoptosis and autophagy. J BUON. 2020 Mar-Apr;25(2):1166-1171 Authors: Xie H, Zhang T, Yang N, Li Z, Liu Y Abstract PURPOSE: The main purpose of the current research work was to investigate the anticancer effects of Mahanimbine alkaloid in human bladder cancer cells along with examining its effects on cellular...
pubmed: cell cycle arrest
Fri Jun 12, 2020 13:36
MicroRNA-9 regulates the proliferation, migration and invasion of human glioma cells by targeting CDH1.
Related ArticlesMicroRNA-9 regulates the proliferation, migration and invasion of human glioma cells by targeting CDH1. J BUON. 2020 Mar-Apr;25(2):1091-1097 Authors: Liu Y, Guo L Abstract PURPOSE: Glioma causes significant mortality worldwide. The currently available treatment strategies are flawed and the therapeutic targets are limited. Accumulating evidence suggests that microRNAs (miRs) are involved in the development and progression of different...
pubmed: cell cycle arrest
Fri Jun 12, 2020 13:36
Anticancer effects of catechin flavonoid in human glioma cells are mediated via autophagy induction, cell cycle arrest, inhibition of cell migration and invasion and targeting MAPK/ERK signalling pathway.
Related ArticlesAnticancer effects of catechin flavonoid in human glioma cells are mediated via autophagy induction, cell cycle arrest, inhibition of cell migration and invasion and targeting MAPK/ERK signalling pathway. J BUON. 2020 Mar-Apr;25(2):1084-1090 Authors: Zhan Sheng Z Abstract PURPOSE: Despite the emergence of innovative cancer treatment strategies, the global burden imposed by malignant glioma is expected to increase. Therefore there...
pubmed: cell cycle arrest
Fri Jun 12, 2020 13:36
Nobiletin flavone inhibits the growth and metastasis of human pancreatic cancer cells via induction of autophagy, G0/G1 cell cycle arrest and inhibition of NF-kB signalling pathway.
Related ArticlesNobiletin flavone inhibits the growth and metastasis of human pancreatic cancer cells via induction of autophagy, G0/G1 cell cycle arrest and inhibition of NF-kB signalling pathway. J BUON. 2020 Mar-Apr;25(2):1070-1075 Authors: Jiang H, Chen H, Jin C, Mo J, Wang H Abstract PURPOSE: The anticancer effects of nobiletin have not been fully explored against the human pancreatic cancer cells. Therefore this study was undertaken to evaluate...
pubmed: cell cycle arrest
Fri Jun 12, 2020 13:36
Scutellarin exerts anticancer effects on human leukemia cells via induction of Sub-G1 cell cycle arrest, apoptosis and also inhibits migration and invasion by targeting Raf/MEK/ERK signalling pathway.
Related ArticlesScutellarin exerts anticancer effects on human leukemia cells via induction of Sub-G1 cell cycle arrest, apoptosis and also inhibits migration and invasion by targeting Raf/MEK/ERK signalling pathway. J BUON. 2020 Mar-Apr;25(2):1050-1055 Authors: Bao J, Xia L, Zhao Y, Xia R Abstract PURPOSE: Leukemia accounts for a significant mortality across the globe every year. The main objective of the present research work was directed towards...
pubmed: cell cycle arrest
Fri Jun 12, 2020 13:36
Anticancer activity of Fisetin against the human osteosarcoma cell lines involves G2/M cell cycle arrest, mitochondrial apoptosis and inhibition of cell migration and invasion.
Related ArticlesAnticancer activity of Fisetin against the human osteosarcoma cell lines involves G2/M cell cycle arrest, mitochondrial apoptosis and inhibition of cell migration and invasion. J BUON. 2020 Mar-Apr;25(2):1022-1027 Authors: Xing C, Zhang Y, Su R, Wu R Abstract PURPOSE: Osteosarcoma is rare but fatal type of human malignancy. The high metastasis rate, late diagnosis, emergence of drug resistance against drugs such as doxorubicin, and...
pubmed: cell cycle arrest
Fri Jun 12, 2020 13:36
Sulforaphane exerts anticancer effects on human liver cancer cells via induction of apoptosis and inhibition of migration and invasion by targeting MAPK7 signalling pathway.
Related ArticlesSulforaphane exerts anticancer effects on human liver cancer cells via induction of apoptosis and inhibition of migration and invasion by targeting MAPK7 signalling pathway. J BUON. 2020 Mar-Apr;25(2):959-964 Authors: Huang B, Lei S, Wang D, Sun Y, Yin J Abstract PURPOSE: This study was undertaken to investigate the anticancer effects of Sulforaphane against liver cancer and to elucidate the underlying molecular mechanisms. ...
pubmed: cell cycle arrest
Fri Jun 12, 2020 13:36
Herbal extract of Artemisia maritima induces selective anti-tumor effects in three human lung carcinoma cells (H1299, NCI-H1437, PC-14) through activating apoptosis-related proteins, G2/M cell cycle arrest and suppression of cell migration.
Related ArticlesHerbal extract of Artemisia maritima induces selective anti-tumor effects in three human lung carcinoma cells (H1299, NCI-H1437, PC-14) through activating apoptosis-related proteins, G2/M cell cycle arrest and suppression of cell migration. J BUON. 2020 Mar-Apr;25(2):869-874 Authors: Tang J, Guo Z, Wen Y, Ao S, Wang J Abstract PURPOSE: Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related deaths in the United States,...
pubmed: cell cycle arrest
Fri Jun 12, 2020 13:36
Antiproliferative effects of Norartocarpetin isoflavone in human lung carcinoma cells are mediated via targeting Ras/Raf/MAPK signalling pathway, mitochondrial mediated apoptosis, S-phase cell cycle arrest and suppression of cell migration and invasion.
Related ArticlesAntiproliferative effects of Norartocarpetin isoflavone in human lung carcinoma cells are mediated via targeting Ras/Raf/MAPK signalling pathway, mitochondrial mediated apoptosis, S-phase cell cycle arrest and suppression of cell migration and invasion. J BUON. 2020 Mar-Apr;25(2):855-861 Authors: Guo N, Xiao Y, Chen D, Wang J Abstract PURPOSE: The main purpose of the current research work was to investigate the anticancer activity...
pubmed: cell cycle arrest
Fri Jun 12, 2020 13:36
Anticancer effects of juglone in OVCAR-3 human ovarian carcinoma are facilitated through programmed cell death, endogenous ROS production, inhibition of cell migration and invasion and cell cycle arrest.
Related ArticlesAnticancer effects of juglone in OVCAR-3 human ovarian carcinoma are facilitated through programmed cell death, endogenous ROS production, inhibition of cell migration and invasion and cell cycle arrest. J BUON. 2020 Mar-Apr;25(2):779-784 Authors: Shi JY, Huang ZR, Gao HY, Xu XL Abstract PURPOSE: Accumulating evidence suggests that Juglone is a potent anticancer molecule of plant origin. However, its anticancer effects have not been...
pubmed: cell cycle arrest
Fri Jun 12, 2020 13:36
Anticancer activity of ursolic acid on human ovarian cancer cells via ROS and MMP mediated apoptosis, cell cycle arrest and downregulation of PI3K/AKT pathway.
Related ArticlesAnticancer activity of ursolic acid on human ovarian cancer cells via ROS and MMP mediated apoptosis, cell cycle arrest and downregulation of PI3K/AKT pathway. J BUON. 2020 Mar-Apr;25(2):750-756 Authors: Lin W, Ye H Abstract PURPOSE: Ovarian cancer (OC) is perhaps the most difficult problem in gynaecologic oncology; in particular the drug-resistant ovarian cancer remains a challenge for the clinicians. Therefore there is a pressing...
pubmed: cell cycle arrest
Fri Jun 12, 2020 13:36
Gammacerane suppresses the growth of human endometrial carcinoma cells via induction of apoptosis, cell cycle arrest, inhibition of cell migration, invasion and STAT3 signaling pathway.
Related ArticlesGammacerane suppresses the growth of human endometrial carcinoma cells via induction of apoptosis, cell cycle arrest, inhibition of cell migration, invasion and STAT3 signaling pathway. J BUON. 2020 Mar-Apr;25(2):723-728 Authors: Wang C, Chen S, Yue X Abstract PURPOSE: This study was conducted to assess the anticancer role of gammacerane against human endometrial cancer. METHODS: The human RL-95 cell line (endometrial cancer)...
pubmed: cell cycle arrest
Fri Jun 12, 2020 13:36
Taraxastane inhibits the proliferation, migration and invasion of human cervical cancer by inducing ROS- mediated necrosis like cell death, cell cycle arrest and modulation of JNK/MAPK signaling pathway.
Related ArticlesTaraxastane inhibits the proliferation, migration and invasion of human cervical cancer by inducing ROS- mediated necrosis like cell death, cell cycle arrest and modulation of JNK/MAPK signaling pathway. J BUON. 2020 Mar-Apr;25(2):716-722 Authors: Hu J, Zhang Y, Guo P, Tang N, Lu Y, Jin Z Abstract PURPOSE: A good number of anticancer studies have focused on the evaluation of plant derived natural products against different types of...
pubmed: cell cycle arrest
Fri Jun 12, 2020 13:36
Silencing of ENO1 inhibits the proliferation, migration and invasion of human breast cancer cells.
Related ArticlesSilencing of ENO1 inhibits the proliferation, migration and invasion of human breast cancer cells. J BUON. 2020 Mar-Apr;25(2):696-701 Authors: Zhang J, Li H, Miao L, Ding J Abstract PURPOSE: Studies have shown that α-enolase ENO1 is involved in the regulation of cancer cell proliferation and metastasis. However, the role of ENO1 is yet to be explored in breast cancer. This study was undertaken to explore the role and therapeutic potential...
pubmed: cell cycle arrest
Fri Jun 12, 2020 13:36
How Cells Handle DNA Breaks during Mitosis: Detection, Signaling, Repair, and Fate Choice.
Related ArticlesHow Cells Handle DNA Breaks during Mitosis: Detection, Signaling, Repair, and Fate Choice. Cells. 2019 09 07;8(9): Authors: Thompson R, Gatenby R, Sidi S Abstract Mitosis is controlled by a complex series of signaling pathways but mitotic control following DNA damage remains poorly understood. Effective DNA damage sensing and repair is integral to survival but is largely thought to occur primarily in interphase and be repressed during...
pubmed: cell cycle arrest
Fri Jun 12, 2020 13:36
The influence of microenvironment on tumor immunotherapy.
Related ArticlesThe influence of microenvironment on tumor immunotherapy. FEBS J. 2019 11;286(21):4160-4175 Authors: Zhang J, Shi Z, Xu X, Yu Z, Mi J Abstract Tumor immunotherapy has achieved remarkable efficacy, with immune-checkpoint inhibitors as especially promising candidates for cancer therapy. However, some issues caused by immunotherapy have raised attention, such as limited efficacy for some patients, narrow antineoplastic spectrum, and adverse...
pubmed: cell cycle arrest
Fri Jun 12, 2020 13:36
Serological Markers Associated With Response to Immune Checkpoint Blockade in Metastatic Gastrointestinal Tract Cancer.
Related ArticlesSerological Markers Associated With Response to Immune Checkpoint Blockade in Metastatic Gastrointestinal Tract Cancer. JAMA Netw Open. 2019 07 03;2(7):e197621 Authors: Lu Z, Zou J, Hu Y, Li S, Zhou T, Gong J, Li J, Zhang X, Zhou J, Lu M, Wang X, Peng Z, Qi C, Li Y, Li J, Li Y, Zou J, Du X, Zhang H, Shen L Abstract Importance: There are a limited number of predictive biomarkers for hyperprogressive disease (HPD), which is induced by...
pubmed: cell cycle arrest
Fri Jun 12, 2020 13:36
Calcineurin-dependent Protein Phosphorylation Changes During Egg Activation in Drosophila melanogaster.
Related ArticlesCalcineurin-dependent Protein Phosphorylation Changes During Egg Activation in Drosophila melanogaster. Mol Cell Proteomics. 2019 03 15;18(Suppl 1):S145-S158 Authors: Zhang Z, Ahmed-Braimah YH, Goldberg ML, Wolfner MF Abstract In almost all animals studied to date, the crucial process of egg activation, by which an arrested mature oocyte transitions into an actively developing embryo, initiates with an increase in Ca2+ in the oocyte's...
pubmed: cell cycle arrest
Fri Jun 12, 2020 13:36
Plasma levels of soluble HLA-G and cytokines in papillary thyroid carcinoma before and after thyroidectomy.
Related ArticlesPlasma levels of soluble HLA-G and cytokines in papillary thyroid carcinoma before and after thyroidectomy. Int J Clin Pract. 2020 Jun 13;:e13585 Authors: Bertol BC, de Araújo JNG, Sadissou IA, Sonon P, Dias FC, Bortolin RH, de Figueiredo-Feitosa NL, Conti de Freitas LC, de Miranda Henrique Tarrapp SR, de Oliveira Ramos CC, Luchessi AD, de Oliveira Crispim Freitas JC, Maciel LMZ, Silbiger VN, Donadi EA Abstract BACKGROUND: Increasing...
Head and Neck
Sun Jun 14, 2020 14:30
Surgical, clinical and functional outcomes of transoral robotic surgery for supraglottic laryngeal cancers: A systematic review.
Related ArticlesSurgical, clinical and functional outcomes of transoral robotic surgery for supraglottic laryngeal cancers: A systematic review. Oral Oncol. 2020 Jun 10;109:104848 Authors: Lechien JR, Fakhry N, Saussez S, Chiesa-Estomba CM, Chekkoury-Idrissi Y, Cammaroto G, Melkane AE, Barillari MR, Crevier-Buchman L, Ayad T, Remacle M, Hans S Abstract BACKGROUND: The aim of this systematic review is to shed light the current indications and outcomes...
Head and Neck
Sun Jun 14, 2020 14:30
Has the chief complaint of patients with COVID-19 disease changed over time?
Related ArticlesHas the chief complaint of patients with COVID-19 disease changed over time? Med Hypotheses. 2020 Jun 07;144:109974 Authors: Dehghani Firouzabadi M, Dehghani Firouzabadi F, Goudarzi S, Jahandideh H, Roomiani M PMID: 32534342 [PubMed - as supplied by publisher]
Head and Neck
Sun Jun 14, 2020 14:30
Multisensory environmental sensitivity in patients with chronic tinnitus.
Related ArticlesMultisensory environmental sensitivity in patients with chronic tinnitus. J Psychosom Res. 2020 May 23;135:110155 Authors: Danioth L, Brotschi G, Croy I, Friedrich H, Caversaccio MD, Negoias S Abstract OBJECTIVE: The study aimed at investigating the sensitivity to noise and chemosensory environmental stressors as well as the relation to perceived stress, depression and anxiety in subjects with chronic tinnitus as compared to subjects...
Head and Neck
Sun Jun 14, 2020 14:30
Bridging bronchus (pseudocarina) and left pulmonary artery sling: A case report and literature review.
Related ArticlesBridging bronchus (pseudocarina) and left pulmonary artery sling: A case report and literature review. Int J Pediatr Otorhinolaryngol. 2020 Jun 03;136:110158 Authors: Yang CJ, Yang C, Farhat L, Gray RT, Guerrero GY, Peek GJ, Shifteh K Abstract Congenital airway malformations can present with respiratory distress, cyanosis, and difficulty feeding in the neonate or infant. Clinical presentation may vary from asymptomatic to fatal airway...
Head and Neck
Sun Jun 14, 2020 14:30
Endoscopic Multimodal Approach to the Treatment of Airway Venous Malformations.
Related ArticlesEndoscopic Multimodal Approach to the Treatment of Airway Venous Malformations. Laryngoscope. 2020 Jun 13;: Authors: Araslanova R, Min-Jung O T, Waner M PMID: 32533772 [PubMed - as supplied by publisher]
Head and Neck
Sun Jun 14, 2020 14:30
Time scale for resolution of olfactory dysfunction in COVID-19.
Related ArticlesTime scale for resolution of olfactory dysfunction in COVID-19. Rhinology. 2020 Jun 13;: Authors: Speth MM, Singer-Cornelius T, Oberle M, Gengler I, Brockmeier SJ, Sedaghat AR Abstract By now, the 2019 novel coronavirus disease (COVID-19), caused by the SARS-CoV-2 virus, is widely recognized around the world as a pandemic that has infected millions and claimed the lives of hundreds of thousands (1). Despite months of mitigation strategies,...
Head and Neck
Sun Jun 14, 2020 14:30
How I do it: Surgical management of maxillary sinus hemangiomas via prelacrimal approach.
Related ArticlesHow I do it: Surgical management of maxillary sinus hemangiomas via prelacrimal approach. Rhinology. 2020 Jun 13;: Authors: Tran LV, Le LT, Wormald PJ Abstract Hemangiomas are tumours originating from the vascular endothelium and can be found throughout the body. These are relatively common in the head and neck regions but very rarely seen in sinonasal region. In the nose and sinuses tumours typically are seen on the septum or lateral...
Head and Neck
Sun Jun 14, 2020 14:30
Seasonality of allergic diseases: Real-world evidence from a nationwide population-based study.
Related ArticlesSeasonality of allergic diseases: Real-world evidence from a nationwide population-based study. Immun Inflamm Dis. 2020 Jun 13;: Authors: Lee YC, Ju HJ, Kwon JW, Bae JM Abstract INTRODUCTION: Seasonal variations of allergic diseases have been of great interest in clinical practice, but large-scale epidemiological data in the real world is lacking. METHODS: We conducted a nationwide, population-based, cross-sectional study...
Head and Neck
Sun Jun 14, 2020 13:00
Salivary detection of SARS-CoV-2 (COVID-19) and implications for oral health-care providers.
Related ArticlesSalivary detection of SARS-CoV-2 (COVID-19) and implications for oral health-care providers. Head Neck. 2020 Jun 13;: Authors: Bajaj N, Granwehr BP, Hanna EY, Chambers MS Abstract The coronavirus disease 2019 (COVID-19) pandemic has become a major public health crisis. The diagnostic and containment efforts for the disease have presented significant challenges for the global health-care community. In this brief report, we provide...
Head and Neck
Sun Jun 14, 2020 13:00
A new endoscopic surgical approach to the larynx, hypopharynx, and neck lymphatics: The robotic-assisted extended "Sistrunk" approach (RESA).
Related ArticlesA new endoscopic surgical approach to the larynx, hypopharynx, and neck lymphatics: The robotic-assisted extended "Sistrunk" approach (RESA). Head Neck. 2020 Jun 13;: Authors: Simon C, Holsinger FC, Rheinwald M, Kemper J, Lambercy K Abstract BACKGROUND: We report on the feasibility of a novel robotic-assisted extended "Sistrunk" approach (RESA) to the larynx, hypopharynx, and lateral neck lymphatics. METHODS: Studies were...
Head and Neck
Sun Jun 14, 2020 13:00
Body composition changes in patients with head and neck cancer under active treatment: a scoping review.
Related ArticlesBody composition changes in patients with head and neck cancer under active treatment: a scoping review. Support Care Cancer. 2020 Jun 13;: Authors: Ferrão B, Neves PM, Santos T, Capelas ML, Mäkitie A, Ravasco P Abstract BACKGROUND: Head and neck cancer patients have the second highest malnutrition prevalence, when compared with other oncological patients. They experience significant weight loss before diagnosis, during and after...
Head and Neck
Sun Jun 14, 2020 13:00
Bilateral carotid artery dissection in a SARS-CoV-2 infected patient: causality or coincidence?
Related ArticlesBilateral carotid artery dissection in a SARS-CoV-2 infected patient: causality or coincidence? J Neurol. 2020 Jun 12;: Authors: Morassi M, Bigni B, Cobelli M, Giudice L, Bnà C, Vogrig A PMID: 32533323 [PubMed - as supplied by publisher]
Head and Neck
Sun Jun 14, 2020 13:00
Morphological Classification of Nostrils and the Role of Sill Augmentation.
Related ArticlesMorphological Classification of Nostrils and the Role of Sill Augmentation. Aesthetic Plast Surg. 2020 Jun 12;: Authors: Sazgar AA, Golparvaran S, Sazgar AK, Teimouri Y, Mirashrafi F Abstract BACKGROUND: Nostril sill asymmetry is one of the most challenging problems in rhinoplasty. Some studies have been performed regarding nostril shape; however, no studies have been conducted on nostril shape in the Persian population. Additionally,...
Head and Neck
Sun Jun 14, 2020 13:00
Temporal bone meningiomas: emphasizing radiologic signs to improve preoperative diagnosis.
Related ArticlesTemporal bone meningiomas: emphasizing radiologic signs to improve preoperative diagnosis. Eur Arch Otorhinolaryngol. 2020 Jun 12;: Authors: Zeleník K, Hanzlíková P, Blatová B, Formánek M, Komínek P Abstract PURPOSE: Temporal bone meningioma is an extremely rare disease. Lack of clinical attention due to its rarity might lead to delayed diagnosis. This short communication aims to emphasize radiologic signs of temporal bone meningiomas...
Head and Neck
Sun Jun 14, 2020 13:00
Effectiveness of planned surveillance for detecting second primary head and neck cancers after endoscopic resection of esophageal squamous cell carcinoma.
Related ArticlesEffectiveness of planned surveillance for detecting second primary head and neck cancers after endoscopic resection of esophageal squamous cell carcinoma. Jpn J Clin Oncol. 2020 Jun 13;: Authors: Shinozaki T, Katada C, Shiga K, Asakage T, Yokoyama T, Yano T, Oda I, Shimizu Y, Takemura K, Ishikawa H, Yokoyama A, Muto M Abstract BACKGROUND: Second primary head and neck cancers after endoscopic resection of esophageal squamous cell carcinoma...
Head and Neck
Sun Jun 14, 2020 13:00
Local tissue electrical parameters predict oral mucositis in HNSCC patients: A diagnostic accuracy double-blind, randomized controlled trial.
Related ArticlesLocal tissue electrical parameters predict oral mucositis in HNSCC patients: A diagnostic accuracy double-blind, randomized controlled trial. Sci Rep. 2020 Jun 12;10(1):9530 Authors: Sanches GLG, da Silva Menezes AS, Santos LI, Durães CP, Fonseca LL, Baldo MP, de Oliveira Faria T, de Araújo Andrade LA, Ekel PI, Santos SHS, de Paula AMB, Farias LC, D'Angelo MFSV, Guimarães ALS Abstract Oral Mucositis (OM) is a common adverse effect...
Head and Neck
Sun Jun 14, 2020 13:00
Bidirectional association between asthma and chronic rhinosinusitis: Two longitudinal follow-up studies using a national sample cohort.
Related ArticlesBidirectional association between asthma and chronic rhinosinusitis: Two longitudinal follow-up studies using a national sample cohort. Sci Rep. 2020 Jun 12;10(1):9589 Authors: Ryu G, Min C, Park B, Choi HG, Mo JH Abstract The aim of this study was to evaluate an epidemiologic association of asthma and chronic rhinosinusitis (CRS) using a national sample cohort of the Korean population. We collected data from the Korean Health Insurance...
Head and Neck
Sun Jun 14, 2020 13:00
Detection of head and neck cancer based on longitudinal changes in serum protein abundance.
Related ArticlesDetection of head and neck cancer based on longitudinal changes in serum protein abundance. Cancer Epidemiol Biomarkers Prev. 2020 Jun 12;: Authors: Lee JY, Shi T, Petyuk VA, Schepmoes AA, Fillmore TL, Wang YT, Cardoni W, Coppit G, Srivastava S, Goodman JF, Shriver CD, Liu T, Rodland KD Abstract BACKGROUND: Approximately 85% of the United States military active duty population is male and less than 50 years of age with elevated levels...
Head and Neck
Sun Jun 14, 2020 13:00
The Mincle/Syk/NF-κB Signalling Circuit is Essential for Maintaining the Protumoral Activities of Tumor-associated Macrophages.
Related ArticlesThe Mincle/Syk/NF-κB Signalling Circuit is Essential for Maintaining the Protumoral Activities of Tumor-associated Macrophages. Cancer Immunol Res. 2020 Jun 12;: Authors: Li C, Xue VW, Wang QM, Lian GY, Huang XR, Lee TL, To KF, Tang PM, Lan HY Abstract Tumor-associated macrophages (TAM) have important roles in cancer promotion, but the signalling behind the formation of protumoral TAM remains understudied. Here, by single-cell RNA...
Head and Neck
Sun Jun 14, 2020 13:00
Intraparotid mucous retention cyst in an infant: a rare case report.
Related ArticlesIntraparotid mucous retention cyst in an infant: a rare case report. Br J Oral Maxillofac Surg. 2020 Jun 09;: Authors: Solano N, Castro B, Perez L, Ramos S, Peraza A Abstract Mucocoeles can be defined as benign lesions that have resulted from extravasation or retention of saliva in the extraglandular spaces, and commonly affect the minor salivary glands. This case details a mucous retention cyst within the parotid gland of an infant,...
Head and Neck
Sun Jun 14, 2020 13:00
Comparison of functional outcomes and health-related quality of life one year after treatment in patients with oral and oropharyngeal cancer treated with three different reconstruction methods.
Related ArticlesComparison of functional outcomes and health-related quality of life one year after treatment in patients with oral and oropharyngeal cancer treated with three different reconstruction methods. Br J Oral Maxillofac Surg. 2020 Jun 09;: Authors: You Q, Jing X, Fan S, Wang Y, Yang Z Abstract We evaluated the functional outcomes and health-related quality of life (HRQoL) of 117 patients (who had had primary operations for oral and oropharyngeal...
Head and Neck
Sun Jun 14, 2020 13:00
Consensus Document of the Spanish Society of Intensive and Critical Care Medicine and Coronary Units (SEMICYUC), the Spanish Society of Otorhinolaryngology and Head and Neck Surgery (SEORL-CCC) and the Spanish Society of Anesthesiology and Resuscitation (SEDAR) on Tracheotomy in Patients with COVID-19 Infection.
Related ArticlesConsensus Document of the Spanish Society of Intensive and Critical Care Medicine and Coronary Units (SEMICYUC), the Spanish Society of Otorhinolaryngology and Head and Neck Surgery (SEORL-CCC) and the Spanish Society of Anesthesiology and Resuscitation (SEDAR) on Tracheotomy in Patients with COVID-19 Infection. Rev Esp Anestesiol Reanim. 2020 Jun 09;: Authors: Martín Delgado MC, Avilés-Jurado FX, Álvarez Escudero J, Álvarez-Santuyano CA, de Haro López...
Head and Neck
Sun Jun 14, 2020 13:00
Invasion of the thoracic duct by postlaryngectomy stomal recurrence: a case report.
Related ArticlesInvasion of the thoracic duct by postlaryngectomy stomal recurrence: a case report. J Med Case Rep. 2020 Jun 13;14(1):68 Authors: Zhu W, Yang X, Wei M, Wang S Abstract BACKGROUND: Postlaryngectomy stomal recurrence can infiltrate the adjacent tissues of tracheal stoma. However, to the best of our knowledge, there is no report about postlaryngectomy stomal recurrence invading the thoracic duct with intra-mass accumulation of chylous...
Head and Neck
Sun Jun 14, 2020 13:00
TP53-Deficient Angiosarcoma Expression Profiling in Rat Model.
Related ArticlesTP53-Deficient Angiosarcoma Expression Profiling in Rat Model. Cancers (Basel). 2020 Jun 10;12(6): Authors: Smyczyńska U, Strzemecki D, Czarnecka AM, Fendler W, Fiedorowicz M, Wełniak-Kamińska M, Guzowska M, Synoradzki K, Cheda Ł, Rogulski Z, Grieb P Abstract Sarcomas are a heterogeneous group of malignant tumors, that develop from mesenchymal cells. Sarcomas are tumors associated with poor prognosis and expected short overall survival....
Head and Neck
Sun Jun 14, 2020 13:00
Angiolipoma in the Head and Neck: Imaging, Diagnosis and Management.
Related ArticlesAngiolipoma in the Head and Neck: Imaging, Diagnosis and Management. Medicina (Kaunas). 2020 Jun 10;56(6): Authors: Reiser V, Haj Yahya B, Chaushu G, Kaplan I, Hamzani Y Abstract Angiolipoma, distinguishable from other lipomas by its excessive degree of vascular vessels, are rare in the head and neck and require unique management. A slow growing mass, located underneath the inferior border of the right mandibular angle of a 51-year-old...
Head and Neck
Sun Jun 14, 2020 13:00
Protective Effect of Alpha-Lipoic Acid on Salivary Dysfunction in a Mouse Model of Radioiodine Therapy-Induced Sialoadenitis.
Related ArticlesProtective Effect of Alpha-Lipoic Acid on Salivary Dysfunction in a Mouse Model of Radioiodine Therapy-Induced Sialoadenitis. Int J Mol Sci. 2020 Jun 10;21(11): Authors: Jung JH, Kim JH, Jung MH, Kim SW, Jeong BK, Woo SH Abstract Radioiodine (RI) therapy is known to cause salivary gland (SG) dysfunction. The effects of antioxidants on RI-induced SG damage have not been well described. This study was performed to investigate the radioprotective...
Head and Neck
Sun Jun 14, 2020 13:00
Tooth extraction before radiotherapy is a risk factor for developing osteoradionecrosis of the jaws: a systematic review.
Related ArticlesTooth extraction before radiotherapy is a risk factor for developing osteoradionecrosis of the jaws: a systematic review. Oral Dis. 2020 Jun 12;: Authors: Lajolo C, Gioco G, Rupe C, Troiano G, Cordaro M, Lucchese A, Paludetti G, Giuliani M Abstract OBJECTIVES: The aim of this Systematic Review is to estimate the osteoradionecrosis rate in patients with head and neck cancer due to teeth extraction performed before radiotherapy and to identify...
Head and Neck
Sat Jun 13, 2020 14:22
Mouse parotid salivary gland organoids for the in vitro study of stem cell radiation response.
Related ArticlesMouse parotid salivary gland organoids for the in vitro study of stem cell radiation response. Oral Dis. 2020 Jun 12;: Authors: Serrano Martinez P, Cinat D, van Luijk P, Baanstra M, de Haan G, Pringle S, Coppes RP Abstract OBJECTIVE: Hyposalivation related xerostomia is an irreversible, untreatable and frequent condition after radiotherapy for head and neck cancer. Stem cell therapy is an attractive option of treatment, but demands knowledge...
Head and Neck
Sat Jun 13, 2020 14:22
Survival impacts of different nodal characteristics and T-classification in N3 nasopharyngeal carcinoma patients.
Related ArticlesSurvival impacts of different nodal characteristics and T-classification in N3 nasopharyngeal carcinoma patients. Oral Oncol. 2020 Jun 09;108:104820 Authors: Lin TY, Lan MY, Tsou HH, Ho CY, Twu CW, Liu YC, Lin PJ, Huang PI, Shiau CY, Lin JC Abstract OBJECTIVES: We investigated the survival impacts of various nodal characteristics and T-classification on nasopharyngeal carcinoma (NPC) patients with the 8th AJCC/UICC staging criteria N3....
Head and Neck
Sat Jun 13, 2020 14:22
Solitary intramuscular myofibroma in an adult: Case report and MR imaging findings.
Related ArticlesSolitary intramuscular myofibroma in an adult: Case report and MR imaging findings. Clin Imaging. 2020 May 30;67:95-100 Authors: de Oliveira Santo ID, Staziaki PV, Prilutskiy A, Sachs TE, Murakami AM Abstract Myofibroma is a benign, soft tissue neoplasm that predominantly affects infants and young children. Most occur in the skin or subcutaneous tissues, with a predilection for the head and neck regions. We describe the magnetic resonance...
Head and Neck
Sat Jun 13, 2020 14:22
Pediatric COVID-19: Systematic review of the literature.
Related ArticlesPediatric COVID-19: Systematic review of the literature. Am J Otolaryngol. 2020 Jun 06;41(5):102573 Authors: Patel NA Abstract OBJECTIVES: There is limited data regarding the demographics and clinical features of SARS-CoV-2 infection in children. This information is especially important as pneumonia is the single leading cause of death in children worldwide. This Systematic Review aims to elucidate a better understanding of the global...
Head and Neck
Sat Jun 13, 2020 14:22
Olfactory and gustatory dysfunctions in COVID-19. First reports of Latin-American ethnic patients.
Related ArticlesOlfactory and gustatory dysfunctions in COVID-19. First reports of Latin-American ethnic patients. Am J Otolaryngol. 2020 Jun 06;41(5):102605 Authors: Chiesa-Estomba CM, Lechien JR, Portillo-Mazal P, Martínez F, Cuauro-Sanchez J, Calvo-Henriquez C, Saussez S PMID: 32531619 [PubMed - as supplied by publisher]
Head and Neck
Sat Jun 13, 2020 14:22
Otoconia degeneration as a consequence of primary hyperparathyroidism.
Related ArticlesOtoconia degeneration as a consequence of primary hyperparathyroidism. Med Hypotheses. 2020 Jun 07;144:109982 Authors: McKenna K, Rahman K, Parham K Abstract Primary hyperparathyroidism (PHPT) is a common endocrine condition which disrupts physiologic calcium regulation. PHPT causes persistent hypercalcemia via the elevated and constant secretion of parathyroid hormone. Due to the effects of parathyroid hormone on target organs such as...
Head and Neck
Sat Jun 13, 2020 14:22
Erratum to: Britton B, Baker AL, Wolfenden L, Wratten C, Bauer J, Beck AK, McCarter K, Harrowfield J, Isenring E, Tang C, Oldmeadow C, and Carter G. Eating As Treatment (EAT): A Stepped-Wedge, Randomized Controlled Trial of a Health Behavior Change Intervention Provided by Dietitians to Improve Nutrition in Patients With Head and Neck Cancer Undergoing Radiation Therapy (TROG 12.03). Int J Radiat Oncol Biol Phys 2019.
Related ArticlesErratum to: Britton B, Baker AL, Wolfenden L, Wratten C, Bauer J, Beck AK, McCarter K, Harrowfield J, Isenring E, Tang C, Oldmeadow C, and Carter G. Eating As Treatment (EAT): A Stepped-Wedge, Randomized Controlled Trial of a Health Behavior Change Intervention Provided by Dietitians to Improve Nutrition in Patients With Head and Neck Cancer Undergoing Radiation Therapy (TROG 12.03). Int J Radiat Oncol Biol Phys 2019. Int J Radiat Oncol Biol Phys. 2020 Jul 01;107(3):606...
Head and Neck
Sat Jun 13, 2020 14:22
Clinically Actional Strategies for Studying Neural Influences in Cancer.
Related ArticlesClinically Actional Strategies for Studying Neural Influences in Cancer. Cancer Cell. 2020 Jun 09;: Authors: Demir IE, Reyes CM, Alrawashdeh W, Ceyhan GO, Deborde S, Friess H, Görgülü K, Istvanffy R, Jungwirth D, Kuner R, Maryanovich M, Na'ara S, Renders S, Saloman JL, Scheff NN, Steenfadt H, Stupakov P, Thiel V, Verma D, Yilmaz BS, White RA, Wang TC, Wong RJ, Frenette PS, Gil Z, Davis BM Abstract Neuro-glial activation is a recently...
Head and Neck
Sat Jun 13, 2020 14:22
Self-Retained Voice Prosthesis in the Decompression of the Odontogenic Keratocyst: A Technical Note.
Related ArticlesSelf-Retained Voice Prosthesis in the Decompression of the Odontogenic Keratocyst: A Technical Note. J Oral Maxillofac Surg. 2020 May 11;: Authors: Keyser B, Lubek JE, Caccamese JF Abstract Decompression of the odontogenic keratocyst has been a long-standing treatment modality in the armamentarium of oral-maxillofacial surgeons. Many different types of effective decompression tubes have been described in the literature. They reduce the...
Head and Neck
Sat Jun 13, 2020 14:22
Skin cancer risk in CHEK2 mutation carriers.
Related ArticlesSkin cancer risk in CHEK2 mutation carriers. J Eur Acad Dermatol Venereol. 2020 Jun 12;: Authors: Bui AN, LeBoeuf NR, Nambudiri VE Abstract CHEK2 mutations have been linked with an increased risk of breast cancer. A unique challenge for oncodermatologists and oncologists is in the monitoring and counseling of patients regarding skin cancer risk due to CHEK2 mutation carrier status. In this review, we highlight current information...
Head and Neck
Sat Jun 13, 2020 14:22
COVID-19 pandemic: Practical considerations on the organization of an allergy clinic - an EAACI/ARIA Position Paper.
Related ArticlesCOVID-19 pandemic: Practical considerations on the organization of an allergy clinic - an EAACI/ARIA Position Paper. Allergy. 2020 Jun 12;: Authors: Pfaar O, Klimek L, Jutel M, Akdis CA, Bousquet J, Breiteneder H, Chinthrajah S, Diamant Z, Eiwegger T, Fokkens WJ, Fritsch HW, Nadeau KC, O'Hehir RE, O'Mahony L, Rief W, Sampath V, Schedlowski M, Torres M, Traidl-Hoffmann C, Wang DY, Zhang L, Bonini M, Brehler R, Brough HA, Chivato T, Del Giacco S, Dramburg...
Head and Neck
Sat Jun 13, 2020 14:22
Utilization of neurolysis in management of refractory head and neck cancer related pain in palliative patients: A retrospective review.
Related ArticlesUtilization of neurolysis in management of refractory head and neck cancer related pain in palliative patients: A retrospective review. J Oral Pathol Med. 2020 Jun 12;: Authors: Khawaja SN, Scrivani SJ Abstract BACKGROUND: Pain is a common symptom of head and neck cancers. In some instances pain may not resolve with conventional modalities and become refractory. Chemical neurolysis is a technique that utilizes chemical neurolytic...
Head and Neck
Sat Jun 13, 2020 14:22
Survival of Patients With Non-Rhabdomyosarcoma Soft Tissue Sarcomas of the Head and Neck.
Related ArticlesSurvival of Patients With Non-Rhabdomyosarcoma Soft Tissue Sarcomas of the Head and Neck. Laryngoscope. 2020 Jun 12;: Authors: Rastatter JC, Sinard RN, Dilger A, Reichek J, Walterhouse DO, Patel U Abstract OBJECTIVE: To evaluate factors associated with overall survival (OS) of patients with non-rhabdomyosarcoma soft tissue sarcomas of the head and neck. STUDY DESIGN: Retrospective cohort study. METHODS: The National...
Head and Neck
Sat Jun 13, 2020 14:22
Efficacy of Mealtime Interventions for Malnutrition and Oral Intake in Persons With Dementia: A Systematic Review.
Related ArticlesEfficacy of Mealtime Interventions for Malnutrition and Oral Intake in Persons With Dementia: A Systematic Review. Alzheimer Dis Assoc Disord. 2020 Jun 10;: Authors: Borders JC, Blanke S, Johnson S, Gilmore-Bykovskyi A, Rogus-Pulia N Abstract Malnutrition and weight loss are highly prevalent in persons with Alzheimer's disease and related dementias. Oral intake is an important interventional target for addressing these nutritional...
Head and Neck
Sat Jun 13, 2020 14:22
A Simple Technique to Measure the Volume of Removed Buccal Fat.
Related ArticlesA Simple Technique to Measure the Volume of Removed Buccal Fat. Aesthet Surg J. 2020 Jun 12;: Authors: Ng CL, Rival R, Solomon P PMID: 32530451 [PubMed - as supplied by publisher]
Head and Neck
Sat Jun 13, 2020 14:22
Vestibular Disorders.
Related ArticlesVestibular Disorders. Dtsch Arztebl Int. 2020 Apr 24;117(17):300-310 Authors: Strupp M, Dlugaiczyk J, Ertl-Wagner BB, Rujescu D, Westhofen M, Dieterich M Abstract BACKGROUND: Recent research findings have improved the understanding of the diagnosis, pathophysiology, genetics, etiology, and treatment of peripheral, central, and functional vestibular vertigo syndromes. METHOD: A literature search, with special attention to...
Head and Neck
Sat Jun 13, 2020 14:22
The impact of allergies and smoking status on nasal mucosa of hypertrophied turbinates - an immunohistologic analysis.
Related ArticlesThe impact of allergies and smoking status on nasal mucosa of hypertrophied turbinates - an immunohistologic analysis. Inhal Toxicol. 2020 Jun 12;:1-8 Authors: Warman M, Tiomkin E, Huszar M, Halperin D, Asher I, Cohen O Abstract Background: Allergies and smoking are common reasons for nasal mucosa inflammations, which in turn, cause nasal obstructions. Nevertheless, the impact of coexisting allergies and smoking on nasal mucosa inflammation...
Head and Neck
Sat Jun 13, 2020 14:22
False-positive reverse transcriptase polymerase chain reaction screening for SARS-CoV-2 in the setting of urgent head and neck surgery and otolaryngologic emergencies during the pandemic: Clinical implications.
Related ArticlesFalse-positive reverse transcriptase polymerase chain reaction screening for SARS-CoV-2 in the setting of urgent head and neck surgery and otolaryngologic emergencies during the pandemic: Clinical implications. Head Neck. 2020 Jun 12;: Authors: Katz AP, Civantos FJ, Sargi Z, Leibowitz JM, Nicolli EA, Weed D, Moskovitz AE, Civantos AM, Andrews DM, Martinez O, Thomas GR Abstract BACKGROUND: No reports describe falsepositive reverse...
Head and Neck
Sat Jun 13, 2020 14:22
Collagen formula with Djulis for improvement of skin hydration, brightness, texture, crow's feet, and collagen content: A double-blind, randomized, placebo-controlled trial.
Related ArticlesCollagen formula with Djulis for improvement of skin hydration, brightness, texture, crow's feet, and collagen content: A double-blind, randomized, placebo-controlled trial. J Cosmet Dermatol. 2020 Jun 12;: Authors: Lin P, Alexander RA, Liang CH, Liu C, Lin YH, Lin YH, Chan LP, Kuan CM Abstract BACKGROUND: The efficacy of Djulis for skin care is currently based on cellular or animal models, and the clinical aspect is not in place....
Head and Neck
Sat Jun 13, 2020 14:22
What the thyroid cancer patient wants to know: ThyCa survey by the American Head and Neck Society Endocrine Surgery Section.
Related ArticlesWhat the thyroid cancer patient wants to know: ThyCa survey by the American Head and Neck Society Endocrine Surgery Section. Head Neck. 2020 Jun 12;: Authors: Dhillon VK, Silver Karcioglu A, Bloom G, Randolph G, Lango M Abstract OBJECTIVE: To survey a large cohort of thyroid cancer survivors from ThyCa on information needs and expectations of their treatment to better understand the pretreatment counseling, information, and support...
Head and Neck
Sat Jun 13, 2020 14:22
Primary cutaneous carcinosarcoma: clinical, histological, and immunohistochemical analysis of eight cases.
Related ArticlesPrimary cutaneous carcinosarcoma: clinical, histological, and immunohistochemical analysis of eight cases. Int J Dermatol. 2020 Jun 12;: Authors: García-Souto F, Pereyra-Rodriguez JJ, Cabrera-Perez R, Durán-Romero AJ, Escudero-Ordoñez J, Conejo-Mir J Abstract BACKGROUND: Cutaneous carcinosarcoma is a rare biphasic tumor comprising malignant epithelial and heterologous mesenchymal elements. Data on the clinical and histopathologic...
Head and Neck
Sat Jun 13, 2020 14:22
Identification of an Immune Score-Based Gene Panel with Prognostic Power for Oral Squamous Cell Carcinoma.
Related ArticlesIdentification of an Immune Score-Based Gene Panel with Prognostic Power for Oral Squamous Cell Carcinoma. Med Sci Monit. 2020 Jun 12;26:e922854 Authors: Huang SN, Li GS, Zhou XG, Chen XY, Yao YX, Zhang XG, Liang Y, Li MX, Chen G, Huang ZG, Dang YW, Li J, Li P, Tang XZ, Rong MH Abstract BACKGROUND Oral squamous cell carcinoma (OSCC) is the sixth most prevalent cancer worldwide, with low 5-year survival rate. To identify novel prognostic...
Head and Neck
Sat Jun 13, 2020 14:22
Should airbags be deactivated for wheelchair-seated drivers?
Related ArticlesShould airbags be deactivated for wheelchair-seated drivers? Traffic Inj Prev. 2020 Jun 12;:1-6 Authors: Hu J, Orton N, Manary MA, Boyle K, Schneider LW Abstract Objective: Field data have shown significant benefit from driver airbag for occupant protection in frontal crashes. However, vehicle modifiers almost always permanently deactivate airbags for wheelchair-seated drivers. The objective of this study was to conduct sled tests...
Head and Neck
Sat Jun 13, 2020 14:22
Racial Disparities in Treatment Patterns and Survival Among Surgically Treated Malignant Pleural Mesothelioma Patients.
Related ArticlesRacial Disparities in Treatment Patterns and Survival Among Surgically Treated Malignant Pleural Mesothelioma Patients. J Immigr Minor Health. 2020 Jun 11;: Authors: Alpert N, van Gerwen M, Steinberg M, Ohri N, Flores R, Taioli E Abstract Surgery may improve survival in malignant pleural mesothelioma (MPM) patients. We examined treatment and survival in black and white surgical MPM patients using the National Cancer Database (NCDB)....
Head and Neck
Sat Jun 13, 2020 13:25
Changes in the use of Otorhinolaryngology Emergency Department during the COVID-19 pandemic: report from Lombardy, Italy.
Related ArticlesChanges in the use of Otorhinolaryngology Emergency Department during the COVID-19 pandemic: report from Lombardy, Italy. Eur Arch Otorhinolaryngol. 2020 Jun 11;: Authors: Elli F, Turri-Zanoni M, Arosio AD, Karligkiotis A, Battaglia P, Castelnuovo P Abstract PURPOSE: This paper aims to report the impact of COVID-19 outbreak on Emergency Ear nose and Throat (ENT) activity, in Lombardy (Italy), during COVID-19 pandemic. METHODS:...
Head and Neck
Sat Jun 13, 2020 13:25
Evaluation of the SAMEO-ATO surgical classification in a Dutch cohort.
Related ArticlesEvaluation of the SAMEO-ATO surgical classification in a Dutch cohort. Eur Arch Otorhinolaryngol. 2020 Jun 11;: Authors: Ten Tije FA, Alkema S, van der Putten L, Koopman JP, Buwalda J, Kramer SE, Pauw RJ, Merkus P, Dutch Cholesteatoma Data Consortium Abstract PURPOSE: Differences in the definition and classification of cholesteatoma hinders comparing of surgical outcomes of cholesteatoma. Uniform registration is necessary to allow...
Head and Neck
Sat Jun 13, 2020 13:25
Application of the new SMS system of cochleovestibular anomalies: our experience with nine cases of type III anomaly.
Related ArticlesApplication of the new SMS system of cochleovestibular anomalies: our experience with nine cases of type III anomaly. Eur Arch Otorhinolaryngol. 2020 Jun 11;: Authors: Grover M, Kanodia A, Gupta G, Preetam C, Samdani S Abstract OBJECTIVE: To present and analyse the radiological findings, surgical findings, pre-implantation and post-implantation speech and hearing outcomes of nine children with SMS Type III cochleovestibular malformation....
Head and Neck
Sat Jun 13, 2020 13:25
Factors That May Affect Rating and Liking Scores of Septorhinoplasty Videos on YouTube.
Related ArticlesFactors That May Affect Rating and Liking Scores of Septorhinoplasty Videos on YouTube. Aesthetic Plast Surg. 2020 Jun 11;: Authors: Demir B, Sahin A, Mammadova U, Mamadlı J Abstract BACKGROUND: Despite the increasing use of videos on social media platforms such as YouTube that inform patients about conditions and procedures, it is an enigma how patients benefit from these videos. Although professional healthcare providers play an...
Head and Neck
Sat Jun 13, 2020 13:25
The Clinical Utility of Neuron-Specific Enolase (NSE) Serum Levels as a Biomarker for Merkel Cell Carcinoma (MCC).
Related ArticlesThe Clinical Utility of Neuron-Specific Enolase (NSE) Serum Levels as a Biomarker for Merkel Cell Carcinoma (MCC). Ann Surg Oncol. 2020 Jun 11;: Authors: van Veenendaal LM, Bertolli E, Korse CM, Klop WMC, Tesselaar MET, van Akkooi ACJ Abstract BACKGROUND: No adequate biomarker for Merkel cell carcinoma (MCC) has been identified. Serum neuron-specific enolase (NSE) has been tested and is commonly used as a biomarker for several other...
Head and Neck
Sat Jun 13, 2020 13:25
Identification of Hub Genes Associated With Development of Head and Neck Squamous Cell Carcinoma by Integrated Bioinformatics Analysis.
Related ArticlesIdentification of Hub Genes Associated With Development of Head and Neck Squamous Cell Carcinoma by Integrated Bioinformatics Analysis. Front Oncol. 2020;10:681 Authors: Li CY, Cai JH, Tsai JJP, Wang CCN Abstract Improved insight into the molecular mechanisms of head and neck squamous cell carcinoma (HNSCC) is required to predict prognosis and develop a new therapeutic strategy for targeted genes. The aim of this study is to identify...
Head and Neck
Sat Jun 13, 2020 13:25

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