Life, Vol. 10, Pages 87: Serum and Plasma Tumor Necrosis Factor Alpha Levels in Individuals with Obstructive Sleep Apnea Syndrome: A Meta-Analysis and Meta-Regression Life doi: 10.3390/life10060087 Authors: Mohammad Moslem Imani Masoud Sadeghi Habibolah Khazaie Mehrdad Emami Dena Sadeghi Bahmani Serge Brand Background: Obstructive sleep apnea syndrome (OSAS) is associated with a variety of inflammatory factors. Specifically, proinflammatory cytokines appear to be associated...
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Medicina, Vol. 56, Pages 295: Who Consult an Adult Psychiatric Emergency Department? Pertinence of Admissions and Opportunities for Telepsychiatry Medicina doi: 10.3390/medicina56060295 Authors: Alessandra Costanza Viridiana Mazzola Michalina Radomska Andrea Amerio Andrea Aguglia Paco Prada Guido Bondolfi François Sarasin Julia Wahener Ambrosetti Background and Objectives: Psychiatric disorders constitute frequent causes of emergency department (ED) admissions...
Medicina, Vol. 56, Pages 290: Effective Preoperative Plasmapheresis Treatment of Severe Hyperthyroidism in a Patient with Giant Toxic Nodular Goiter and Methimazole-Induced Agranulocytosis Medicina doi: 10.3390/medicina56060290 Authors: Barwinek Gąsior-Perczak Trepka Szczodry Kopczyński Sitarz-Żelazna Kowalska Agranulocytosis is a rare but very serious complication of thyrostatic therapy. In severe hyperthyroidism, the removal of circulating thyroid hormones...
Medicina, Vol. 56, Pages 293: Ectopic Cervical Pregnancy: Treatment Route Medicina doi: 10.3390/medicina56060293 Authors: Stabile Mangino Romano Zinicola Ricci Background and objectives: Cervical pregnancy (CP) is a rare form of ectopic pregnancy (EP) in which the embryo implants and grows inside the endocervical canal. Early diagnosis is essential in order to allow conservative medical and surgical treatments. Although many treatment approaches are disponible, the most...
Medicina, Vol. 56, Pages 292: Acute Effects of a Heat-Not-Burn Tobacco Product on Pulmonary Function
Medicina, Vol. 56, Pages 292: Acute Effects of a Heat-Not-Burn Tobacco Product on Pulmonary Function Medicina doi: 10.3390/medicina56060292 Authors: Pataka Kotoulas Chatzopoulos Grigoriou Sapalidis Kosmidis Vagionas Perdikouri Drevelegas Zarogoulidis Argyropoulou Background and objectives: During the last decade, conventional tobacco smoking is experiencing a decline and new smoking products have been introduced. IQOS (“I-Quit-Ordinary-Smoking”)...
Medicina, Vol. 56, Pages 291: Dropped Head Syndrome Attenuation by Hybrid Assistive Limb: A Preliminary Study of Three Cases on Cervical Alignment during Walking Medicina doi: 10.3390/medicina56060291 Authors: Kadone Miura Kubota Abe Shimizu Hada Suzuki Sankai Koda Yamazaki Background and Objectives: Dropped head syndrome (DHS) is characterized by apparent neck extensor muscle weakness and difficulty in extending the neck to raise the head against...
Medicina, Vol. 56, Pages 289: Nutritional Support in Coronavirus 2019 Disease Medicina doi: 10.3390/medicina56060289 Authors: Stachowska Folwarski Jamioł-Milc Maciejewska Skonieczna-Żydecka The epidemic that broke out in Chinese Wuhan at the beginning of 2020 presented how important the rapid diagnosis of malnutrition (elevating during intensive care unit stay) and the immediate implementation of caloric and protein-balanced nutrition care are. According to specialists...
Medicina, Vol. 56, Pages 294: Dental Care Provision during Coronavirus Disease 2019 (COVID-19) Pandemic: The Importance of Continuous Support for Vulnerable Patients Medicina doi: 10.3390/medicina56060294 Authors: Dziedzic Tanasiewicz Tysiąc-Miśta As a result of the ongoing 2019 coronavirus disease (COVID-19) pandemic, the medical and dental services across the world have to tackle unprecedented situations, providing essential care and professional support. The global health...
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Medicines, Vol. 7, Pages 32: Circulatory Failure among Hospitalizations for Heatstroke in the United States Medicines doi: 10.3390/medicines7060032 Authors: Tarun Bathini Charat Thongprayoon Tananchai Petnak Api Chewcharat Wisit Cheungpasitporn Boonphiphop Boonpheng Ronpichai Chokesuwattanaskul Narut Prasitlumkum Saraschandra Vallabhajosyula Wisit Kaewput Background: This study aimed to assess the risk factors and the association of circulatory failure with...
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Metabolites, Vol. 10, Pages 243: Machine Learning Applications for Mass Spectrometry-Based Metabolomics Metabolites doi: 10.3390/metabo10060243 Authors: Ulf W. Liebal An N. T. Phan Malvika Sudhakar Karthik Raman Lars M. Blank The metabolome of an organism depends on environmental factors and intracellular regulation and provides information about the physiological conditions. Metabolomics helps to understand disease progression in clinical settings or estimate metabolite...
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Microorganisms, Vol. 8, Pages 897: Amplicon-Based High-Throughput Sequencing Method Capable of Species-Level Identification of Coagulase-Negative Staphylococci in Diverse Communities Microorganisms doi: 10.3390/microorganisms8060897 Authors: Emiel Van Reckem Luc De Vuyst Frédéric Leroy Stefan Weckx Coagulase-negative staphylococci (CNS) make up a diverse bacterial group, appearing in a myriad of ecosystems. To unravel the composition of staphylococcal communities in these microbial...
Microorganisms, Vol. 8, Pages 896: Genomic Characterisation of a Multiple Drug Resistant IncHI2 ST4 Plasmid in Escherichia coli ST744 in Australia Microorganisms doi: 10.3390/microorganisms8060896 Authors: Tiziana Zingali Toni A. Chapman John Webster Piklu Roy Chowdhury Steven P. Djordjevic Antibiotic resistance genes (ARGs) including those from the blaCTX-M family and mcr-1 that encode resistance to extended spectrum β–lactams and colistin, respectively,...
Microorganisms, Vol. 8, Pages 895: Diversity of Pectobacteriaceae Species in Potato Growing Regions in Northern Morocco Microorganisms doi: 10.3390/microorganisms8060895 Authors: Saïd Oulghazi Mohieddine Moumni Slimane Khayi Kévin Robic Sohaib Sarfraz Céline Lopez-Roques Céline Vandecasteele Denis Faure Dickeya and Pectobacterium pathogens are causative agents of several diseases that affect many crops worldwide. This work investigated the species diversity of these...
Microorganisms, Vol. 8, Pages 894: Association between Active Helicobacter pylori Infection and Glaucoma: A Systematic Review and Meta-Analysis Microorganisms doi: 10.3390/microorganisms8060894 Authors: Michael Doulberis Apostolis Papaefthymiou Stergios A. Polyzos Panagiotis Bargiotas Christos Liatsos David Shiva Srivastava Christos Zavos Panagiotis Katsinelos Jannis Kountouras Background: Glaucoma is the second most common cause of blindness worldwide affecting...
Microorganisms, Vol. 8, Pages 893: Genomic and Proteomic Characterization of the Extended-Spectrum β-Lactamase (ESBL)-Producing Escherichia coli Strain CCUG 73778: A Virulent, Nosocomial Outbreak Strain Microorganisms doi: 10.3390/microorganisms8060893 Authors: Daniel Jaén-Luchoro Antonio Busquets Roger Karlsson Francisco Salvà-Serra Christina Åhrén Nahid Karami Edward R. B. Moore Escherichia coli strain CCUG 78773 is a virulent extended-spectrum β-lactamase...
Microorganisms, Vol. 8, Pages 892: BTV-14 Infection in Sheep Elicits Viraemia with Mild Clinical Symptoms Microorganisms doi: 10.3390/microorganisms8060892 Authors: John Flannery Lorraine Frost Petra Fay Hayley Hicks Mark Henstock Marcin Smreczak Anna Orłowska Paulina Rajko-Nenow Karin Darpel Carrie Batten In 2011, Bluetongue virus serotype 14 (BTV-14) was detected in Russia during routine surveillance, and was subsequently found in a number of European countries....
Microorganisms, Vol. 8, Pages 891: Roles of Macrophage Migration Inhibitory Factor in Dengue Pathogenesis: From Pathogenic Factor to Therapeutic Target Microorganisms doi: 10.3390/microorganisms8060891 Authors: Lai Chao Yeh Dengue virus (DENV) infection is the most prevalent mosquito-borne viral infection and can lead to severe dengue hemorrhagic fever (DHF) and even life-threatening dengue shock syndrome (DSS). Although the cytokine storm has been revealed as a critical factor...
Microorganisms, Vol. 8, Pages 890: Oxidative Stress and Antioxidant Responses of Phormidium ambiguum and Microcystis aeruginosa Under Diurnally Varying Light Conditions Microorganisms doi: 10.3390/microorganisms8060890 Authors: Muhetaer Jayasanka Fujino Two harmful cyanobacteria species (Phormidium ambiguum and Microcystis aeruginosa) were exposed to diurnal light-intensity variation to investigate their favorable and stressed phases during a single day. The photosynthetically...
Microorganisms, Vol. 8, Pages 888: Biochemical and Genetic Analysis of 4-Hydroxypyridine Catabolism in Arthrobacter sp. Strain IN13 Microorganisms doi: 10.3390/microorganisms8060888 Authors: Vaitekūnas Gasparavičiūtė Stankevičiūtė Urbelis Meškys N-Heterocyclic compounds are widely spread in the biosphere, being constituents of alkaloids, cofactors, allelochemicals, and artificial substances. However, the fate of such compounds including a catabolism of hydroxylated...
Microorganisms, Vol. 8, Pages 889: Complete Genome of Isoprene Degrading Nocardioides sp. WS12 Microorganisms doi: 10.3390/microorganisms8060889 Authors: Gibson Larke-Mejía Murrell Isoprene is a climate-active gas whose wide-spread global production stems mostly from terrestrial plant emissions. The biodegradation of isoprene is carried out by a number of different bacteria from a wide range of environments. This study investigates the genome of a novel isoprene degrading bacterium...
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Molecules, Vol. 25, Pages 2751: Supramolecular Peptide Assemblies as Antimicrobial Scaffolds Molecules doi: 10.3390/molecules25122751 Authors: Andrew W. Simonson Matthew R. Aronson Scott H. Medina Antimicrobial discovery in the age of antibiotic resistance has demanded the prioritization of non-conventional therapies that act on new targets or employ novel mechanisms. Among these, supramolecular antimicrobial peptide assemblies have emerged as attractive therapeutic platforms,...
Molecules, Vol. 25, Pages 2750: Yeast Telomerase RNA Flexibly Scaffolds Protein Subunits: Results and Repercussions Molecules doi: 10.3390/molecules25122750 Authors: David C. Zappulla It is said that “hindsight is 20-20”, so, given the current year, it is an opportune time to review and learn from experiences studying long noncoding RNAs. Investigation of the Saccharomyces cerevisiae telomerase RNA, TLC1, has unveiled striking flexibility in terms of both structural...
Molecules, Vol. 25, Pages 2749: How ‘Protein-Docking’ Translates into the New Emerging Field of Docking Small Molecules to Nucleic Acids? Molecules doi: 10.3390/molecules25122749 Authors: Francesca Tessaro Leonardo Scapozza In this review, we retraced the ‘40-year evolution’ of molecular docking algorithms. Over the course of the years, their development allowed to progress from the so-called ‘rigid-docking’ searching methods to the more sophisticated...
Molecules, Vol. 25, Pages 2747: Influence of Terpene Type on the Release from an O/W Nanoemulsion: Experimental and Theoretical Studies Molecules doi: 10.3390/molecules25122747 Authors: Miastkowska Śliwa The interaction between a drug molecule and its carrier’s components is an important factor which influences the drug release profile. For this purpose, molecular dynamics (MD) may be the in silico tool which can help to understand the mechanism of drug loading/release....
Molecules, Vol. 25, Pages 2745: Recent Advances in the Production and Applications of Ellagic Acid and Its Derivatives. A Review Molecules doi: 10.3390/molecules25122745 Authors: Dmitry D. Evtyugin Sandra Magina Dmitry V. Evtuguin Ellagitannins (ETs), characterized by their diversity and chemical complexity, belong to the class of hydrolysable tannins that, via hydrolysis under acidic or alkaline conditions, can yield ellagic acid (EA). They are mostly found as a part of extractives...
Molecules, Vol. 25, Pages 2748: Comparison of the Physical and Sensory Properties of Hybrid Citrus Fruit Jaffa® Sweetie in Relation to the Parent Fruits Molecules doi: 10.3390/molecules25122748 Authors: Martyna Lubinska-Szczygeł Żaneta Polkowska Tomasz Dymerski Shela Gorinstein In the presented study, an overall Jaffa sweetie evaluation was made to find a correlation between Citrus grandis Osbeck × Citrus paradisi Macf. and its parent fruits’ (Citrus grandis...
Molecules, Vol. 25, Pages 2746: Extract of Juniperus indica Bertol Synergizes with Cisplatin to Inhibit Oral Cancer Cell Growth via Repression of Cell Cycle Progression and Activation of the Caspase Cascade Molecules doi: 10.3390/molecules25122746 Authors: Xiao-Fan Huang Kai-Fu Chang Shan-Chih Lee Chia-Yu Li Hung-Hsiu Liao Ming-Chang Hsieh Nu-Man Tsai Oral cancer—a type of head and neck cancer—is estimated to be the fifth most common cancer in Taiwan....
Molecules, Vol. 25, Pages 2744: Production and Potential Applications of Bioconversion of Chitin and Protein-Containing Fishery Byproducts into Prodigiosin: A Review Molecules doi: 10.3390/molecules25122744 Authors: San-Lang Wang Van Bon Nguyen Chien Thang Doan Thi Ngoc Tran Minh Trung Nguyen Anh Dzung Nguyen The technology of microbial conversion provides a potential way to exploit compounds of biotechnological potential. The red pigment prodigiosin (PG) and other PG-like...
Molecules, Vol. 25, Pages 2743: Solubility Data of the Bioactive Compound Piperine in (Transcutol + Water) Mixtures: Computational Modeling, Hansen Solubility Parameters and Mixing Thermodynamic Parameters Molecules doi: 10.3390/molecules25122743 Authors: Faiyaz Shakeel Nazrul Haq Sultan Alshehri The solubility values and thermodynamic parameters of a natural phytomedicine/nutrient piperine (PPN) in Transcutol-HP (THP) + water combinations were determined. The mole fraction solubilities...
Molecules, Vol. 25, Pages 2742: Chemical and Electrochemical Recycling of End-Use Poly(ethylene Terephthalate) (PET) Plastics in Batch, Microwave and Electrochemical Reactors Molecules doi: 10.3390/molecules25122742 Authors: Tessa H. T. Myren Taylor A. Stinson Zachary J. Mast Chloe G. Huntzinger Oana R. Luca This work describes new methods for the chemical recycling of end-use poly(ethylene terephthalate) (PET) in batch, microwave and electrochemical reactors. The reactions...
Molecules, Vol. 25, Pages 2741: Structural Characterization, DFT Calculation, NCI, Scan-Rate Analysis and Antifungal Activity against Botrytis cinerea of (E)-2-{[(2-Aminopyridin-2-yl)imino]-methyl}-4,6-di-tert-butylphenol (Pyridine Schiff Base) Molecules doi: 10.3390/molecules25122741 Authors: Alexander Carreño Dayán Páez-Hernández Plinio Cantero-López César Zúñiga Jan Nevermann Angélica Ramírez-Osorio Manuel Gacitúa Poldie Oyarzún Felipe Sáez-Cortez Rubén Polanco...
Molecules, Vol. 25, Pages 2739: Asymmetric Synthesis of Tailor-Made Amino Acids Using Chiral Ni(II) Complexes of Schiff Bases. An Update of the Recent Literature Molecules doi: 10.3390/molecules25122739 Authors: Yupiao Zou Jianlin Han Ashot S. Saghyan Anna F. Mkrtchyan Hiroyuki Konno Hiroki Moriwaki Kunisuke Izawa Vadim A. Soloshonok Tailor-made amino acids are indispensable structural components of modern medicinal chemistry and drug design. Consequently, stereo-controlled...
Molecules, Vol. 25, Pages 2740: Excited-State Proton Transfer in 8-Azapurines I: A Kinetic Analysis of 8-Azaxanthine Fluorescence Molecules doi: 10.3390/molecules25122740 Authors: Jacek Wierzchowski Bogdan Smyk A super-continuum white laser with a half-pulse width of ~75 ps was used to observe the kinetics of a postulated excited-state proton transfer in 8-azaxanthine and its 8-methyl derivative. Both compounds exhibited dual emissions in weakly acidified alcoholic media, but only...
Molecules, Vol. 25, Pages 2737: Dehydrozingerone, a Curcumin Analog, as a Potential Anti-Prostate Cancer Inhibitor In Vitro and In Vivo Molecules doi: 10.3390/molecules25122737 Authors: Mapoung Suzuki Fuji Naiki-Ito Kato Yodkeeree Sakorn Ovatlarnporn Takahashi Limtrakul (Dejkriengkraikul) Curcumin (Cur) exhibits biological activities that support its candidacy for cancer treatment. However, there are limitations to its pharmacological effects, such...
Molecules, Vol. 25, Pages 2734: Screening of Phosphodiesterase-5 Inhibitors and Their Analogs in Dietary Supplements by Liquid Chromatography–Hybrid Ion Trap–Time of Flight Mass Spectrometry Molecules doi: 10.3390/molecules25122734 Authors: Unyong Kim Hyun-Deok Cho Myung Hee Kang Joon Hyuk Suh Han Young Eom Junghyun Kim Sumin Seo Gunwoo Kim Hye Ryoung Koo Nary Ha Un Tak Song Sang Beom Han An accurate and reliable method based on ion trap–time...
Molecules, Vol. 25, Pages 2736: Erratum:Dragan, E.S., et al., Contribution of Cross-Linker and Silica Morphology on Cr(VI) Sorption Performances of Organic Anion Exchangers Embedded into Silica Pores. Molecules 2020, 25, 1249. Molecules doi: 10.3390/molecules25122736 Authors: Ecaterina Stela Dragan Doina Humelnicu The authors wish to make a change to the published paper [...]
Molecules, Vol. 25, Pages 2735: Cordycepin for Health and Wellbeing: A Potent Bioactive Metabolite of an Entomopathogenic Cordyceps Medicinal Fungus and Its Nutraceutical and Therapeutic Potential Molecules doi: 10.3390/molecules25122735 Authors: Syed Amir Ashraf Abd Elmoneim O. Elkhalifa Arif Jamal Siddiqui Mitesh Patel Amir Mahgoub Awadelkareem Mejdi Snoussi Mohammad Saquib Ashraf Mohd Adnan Sibte Hadi Cordyceps is a rare naturally occurring entomopathogenic...
Molecules, Vol. 25, Pages 2738: Chiral Aspects of Local Anesthetics Molecules doi: 10.3390/molecules25122738 Authors: Ružena Čižmáriková Jozef Čižmárik Jindra Valentová Ladislav Habala Mário Markuliak Thanks to the progress made in chemical technology (particularly in the methodologies of stereoselective syntheses and analyses) along with regulatory measures, the number of new chiral drugs registered in the form of pure enantiomers has increased over the past decade. In addition,...
Molecules, Vol. 25, Pages 2732: Optimization of QuEChERS Method for Simultaneous Determination of Neonicotinoid Residues in Pollinator Forage Molecules doi: 10.3390/molecules25122732 Authors: Maura J. Hall Viet Dang Steven P. Bradbury Joel R. Coats Consistent with the large-scale use of pesticide seed treatments in U.S. field crop production, there has been an increased use of neonicotinoid-treated corn and soybean seed over the past decade. Neonicotinoids can move downwind...
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