The aim of this study was to determine the rate of undetected additional anomalies following a prenatal diagnosis of isolated oral cleft. Data of all infants with a prenatal diagnosis of isolated oral cleft born between 2000 and 2015 were studied retrospectively. Additional anomalies detected after birth were categorized as minor or major and included structural and chromosomal anomalies. Isolated clefts of the lip (CL), lip and alveolus (CLA) and lip, alveolus, and palate (CLAP) were diagnosed prenatally...
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Postlaryngectomy stomal recurrence can infiltrate the adjacent tissues of tracheal stoma. However, to the best of our knowledge, there is no report about postlaryngectomy stomal recurrence invading the thoraci...
Breast cancer is the most common cancer in women. However, in the management of breast cancer, paraneoplastic neurological syndromes represent a diagnostic and therapeutic challenge. The diagnosis of paraneopl...
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The footpad inoculation model is a valuable tool for characterizing viral-induced neuroinflammatory responses in vivo. In particular, it provides a clear assessment of viral kinetics and associated immunopathological processes initiated in the peripheral nervous system.
The objective is to fractionate and isolate bioactive small molecules, peptides from a complex plant extract, and proteins from pathogenic microbes by employing liquid-phase isoelectric focusing (IEF) method. Further, the separated molecules were identified and their bioactivity confirmed.
Double in utero electroporation allows targeting cell populations that are spatially and temporally separated. This technique is useful to visualize interactions between those cell populations using fluorescent proteins in normal conditions but also after functional experiments to perturb genes of interest.
In the present protocol, we explain how to easily process and culture tonsillar mononuclear cells from healthy humans undergoing partial surgical tonsillectomy to study innate immune responses upon activation, mimicking viral infection in mucosal tissues.
This publication describes a protocol for the isolation of nuclei from mature adipocytes, purification by fluorescence-activated sorting, and single-cell level transcriptomics.
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Publication date: Available online 13 June 2020Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Hirokazu Kimura, Hiromu Kurusu, Mitsuru Sada, Daisuke Kurai, Koichi Murakami, Wataru Kamitani, Haruyoshi Tomita, Kazuhiko Katayama, Akihide Ryo
Publication date: Available online 12 June 2020Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Pascal Haimerl, Ulrike Bernhardt, Sonja Schindela, Fiona DR. Henkel, Antonie Lechner, Ulrich M. Zissler, Xavier Pastor, Dominique Thomas, Alexander Cecil, Yan Ge, Mark Haid, Cornelia Prehn, Janina Tokarz, Matthias Heinig, Jerzy Adamski, Carsten B. Schmidt-Weber, Adam M. Chaker, Julia Esser-von Bieren
Publication date: Available online 12 June 2020Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Edwin H. Kim, Tamara T. Perry, Robert A. Wood, Donald YM. Leung, M. Cecilia Berin, A Wesley Burks, Christine B Cho, Stacie M. Jones, Amy Scurlock, Scott H. Sicherer, Alice K. Henning, Peter Dawson, Robert W. Lindblad, Marshall Plaut, Hugh A. Sampson, Consortium for Food Allergy Research (CoFAR)
Publication date: Available online 12 June 2020Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Kellen J. Cavagnero, Taylor A. Doherty
Publication date: Available online 12 June 2020Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Hans Bisgaard, Sarah Nørgaard, Astrid Sevelsted, Bo Chawes, Jakob Stokholm, Erik Lykke Mortensen, Charlotte Suppli Ulrik, Klaus Bønnelykke
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Make traveling easier. (Tim Gouw via Unsplash/)Traveling comes with its own unique form of exhaustion, between the cramped seats, long layovers, overstuffed suitcases, and time changes. With so many external factors outside of a traveler’s control, considering the little details can make a big difference in ensuring some semblance of comfort and convenience during the travel process. We picked a few of our favorite travel accessories that are guaranteed to smooth over any bump that comes your way...
In this Depression-era stalwart, soft, chewy white bread (homemade or store-bought) is an ideal canvas for butter and pickles. (Jennifer May/)Have you ever stopped to ask yourself why bread-and-butter pickles are called bread-and-butter pickles? “I thought they were called that because they’re sweeter and less vinegary,” a friend tells me. “You know, smooth as butter.”I had never questioned their name either, but rather quietly, to myself, word-associated bread-and-butter with “reliable”—just like...
No more awkward transitions. (Teemu Paananen via Unsplash./)If you speak on a regular basis at conferences, workshops, or in company boardrooms you’ll know that you can’t always rely on in-house equipment to be charged up and ready to go. Prepping slides, memorizing key messaging, and editing your content into a succinct and impactful presentation is challenging enough. Dealing with wonky slide transitions and technical glitches can knock you off of your game altogether. Pack your own presentation...
With a few accessories, a tablet can become a sleek laptop alternative. ( Brooke Cagle / Unsplash/)Tablets pack all the power of smartphones behind a larger screen, which comes in handy when you’re watching Netflix or reviewing documents on the go. These devices are so versatile that you can even grab a clip-on keyboard and a wireless mouse, and turn your tablet into a light, slim laptop replacement.In recent years, the market has been flooded with many different kinds of tablets, but the plethora...
The official version of Android 11 is coming later this year—depending on what phone you have. (Android/)If you clicked into this article, then you’re the kind of person who gets excited about mobile operating system updates. Don’t worry, you’re among friends here. So, if you were enthusiastically waiting for the new Android 11 public beta to drop, this was a thrilling week for you. As with most modern operating system updates, Android 11 makes more tweaks than it does massive changes. If you’re...
Portable data storage options. (Jonathan Farber via Unsplash/)There are a number of factors to consider when it comes to external hard drives. How much data are you likely to need to store? Do you ever plan to disconnect it from your home computer or gaming console? Is it likely that the hard drive will end up in rough situations? Thankfully, there are plenty of options for everyone, including those who are most concerned with portability and IRL storage space.Tiny datas. (Amazon/)This hard drive...
Black Lives Matters protests have continue from Memorial Day through mid-June. (Patrick Behn/Pixabay/)Wear a mask. Stay hydrated. Use an encrypted messaging app.Sounds simple right? Whether you’re out protesting for Breonna Taylor, George Floyd, Tony McDade, or the hundreds of other Black Americans who’ve died from systemic racism in health care, community policing, and more, key precautions like these will keep you safe and strong as you march down the streets.For the past few weeks at PopSci, we’ve...
Items to make traveling with your little ones easier. (Octav Cado via Unsplash/)Traveling with young kids and babies can be a tough and thankless task. Parents often have to deal with long lines, delays, unexpected accidents, and incessant crying. Single dads may not have access to changing stations and other parents may have to do a quick diaper change in the most inconvenient of locations. Occupying your child’s attention while on the road is no easy feat, either. Luckily, money helps alleviate...
A place to play. (Amazon /)New parents are always reluctant to let go of their little ones. But let us assure you there will come a time when both you and baby need your space and these playards are the perfect place to let baby have some not-so-free time. Playards give baby a chance to learn the ropes, test out their first steps, play independently and explore without their parents assisting every movement. These playards offer unique benefits compared to their competitors.Fields of green. (Amazon/)The...
Sit back and relax. (Amazon/)Swinging above the ground is one of those rare feelings that’s just about as close to weightlessness as you can get without jumping in the water. From rocking chairs to hammocks, many inventions are designed for the sole purpose of leveling up on the relief that comes from taking a seat. If you have an outdoor space that you’re looking to claim or a corner of your living area that could use some cozying up, a swinging chair will get you where you want to go and keep you...
Always have a place in the shade. ( Aldo Terrazas via Unsplash/)When the weather warms up and the sun comes out, your home’s outdoor space becomes an instant focal point for relaxation and entertaining. No matter what size your yard, adequate shade from the sun is the key to enjoying yourself on a beautiful day. If you have a grilling and picnic area, a large open lawn, or even a small garden with paving stones, there’s a sun-blocking device out there that will match your decor, keep you and your...
Say goodbye to single-use plastic. (Asnim Asnim via Unsplash/)Moving toward a zero-waste lifestyle requires changing habits. The best eco-friendly products help you make the transition seamlessly, with a minimum of fuss. If the convenience of air-tight zippered bags or plastic-wrapped PB+J is part of your everyday routine, washable silicone or cloth bags and beeswax wraps are a great solution. With these striking choices in your kitchen, you might even enjoy packing your lunch before you head off...
Medical physicist Joanna Harper is going the distance in researching when and how trans athletes should qualify for women's sports. (Jon Enoch/)Popular Science’s Play issue is now available to everyone. Read it now, no app or credit card required.Joanna Harper’s research started not in a lab, but on the track. Though she didn’t have a background in sports science—she held a master’s in medical physics, and her work involved tailoring cancer radiation treatments—she was an athlete in a unique situation:...
Pepper spray packs a serious punch. ( Spenser / Unsplash/)If you’ve ever accidentally touched your eyes after handling slices of jalapeño, you know the deep, searing pain that quickly follows. Now imagine that but 200 times worse. That’s what it’s like to be pepper-sprayed.Let that sink in for a moment.Pepper spray, along with tear gas, is one of the most common weapons in police departments’ crowd control arsenals. It was frequently used against protesters during the Occupy Wall Street movement...
Need to store more? (Neal E. Johnson via Unsplash/)There was a time not long ago when almost any solid state drive would cost you an arm and a leg. That’s no longer the case. In fact, the standard for fast storage drives are now affordable even in sturdy and compact portable form. These portable drives can allow you to both reduce load times on your favorite games while easily bringing them with you to a friends house. You can store your design portfolio on one of these bad boys and have it handy...
The PS5 ditches the straight lines for curved edges. (Sony/)Video game console releases don’t work like typical gadget announcements—they happen in slow motion. We heard the first details about Sony’s new PlayStation 5 more than a year ago, but this week we finally got our first look at the hardware, as well as a bunch of new games for the system. The case is a departure from the PS4’s current design. Its curved sides and flared white outer layer make it very easy to discern from other consoles,...
The Lovell Telescope in the UK has found 32 bursts from deep space, helping a team of astronomers uncover a pattern in their flashes. (Kristi Mickaliger/)Astronomers have spent six years watching an unknown object a million, billion light years away explode again and again. They still don’t know what’s expelling the violent bursts of energy, but one team thinks they’ve figured out at least when the extragalactic pyrotechnics are likely to go off. If they’re right, the object will be shooting out...
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Publication date: Available online 13 June 2020Source: International Journal of Radiation Oncology*Biology*PhysicsAuthor(s): Neil R. Parikh, Eric M. Chang, Nicholas G. Nickols, Matthew B. Rettig, Ann C. Raldow, Michael L. Steinberg, Bridget F. Koontz, Neha Vapiwala, Curtiland Deville, Felix Y. Feng, Daniel E. Spratt, Robert E. Reiter, Ryan Phillips, Piet Ost, Phuoc T. Tran, Amar U. Kishan
Publication date: Available online 13 June 2020Source: International Journal of Radiation Oncology*Biology*PhysicsAuthor(s): Kevin L.M. Chua, Michael Fehlings, Eugenia L.L. Yeo, Alessandra Nardin, Hermi Sumatoh, Pek Lim Chu, Wen-long Nei, Enya H.W. Ong, Wai Yee Woo, Kar Perng Low, Haitao Wang, Dennis J.J. Poon, Zhong-guo Liang, Kai Yao, Luo Huang, Chee Keong Toh, Mei-Kim Ang, Mohamad Farid, Xin Min Cheng, Ravindran Kanesvaran
Publication date: Available online 13 June 2020Source: International Journal of Radiation Oncology*Biology*PhysicsAuthor(s): Devarati Mitra, Andrew Bishop, B. Ashleigh Guadagnolo
Publication date: Available online 13 June 2020Source: International Journal of Radiation Oncology*Biology*PhysicsAuthor(s): Sondos Zayed, Hanbo Chen, Emma Ali, George B. Rodrigues, Andrew Warner, David A. Palma, Alexander V. Louie
Publication date: Available online 12 June 2020Source: International Journal of Radiation Oncology*Biology*PhysicsAuthor(s): Maud Jaccard, Thomas Zilli, Angèle Dubouloz, Lluís Escude, Sandra Jorcano, Nadine Linthout, Samuel Bral, Wilko Verbakel, Anna Bruynzeel, Mikko Björkqvist, Heikki Minn, Lev Tsvang, Zvi Symon, Joana Lencart, Angelo Oliveira, Zeynep Ozen, Ufuk Abacioglu, Juan María Pérez-Moreno, Carmen Rubio, Michel Rouzaud
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Publication date: Available online 13 June 2020Source: Dental MaterialsAuthor(s): Franziska Ehlicke, Jonathan Berndt, Nina Marichikj, Doris Steinmüller-Nethl, Heike Walles, Ernst-Ulrich Berndt, Jan Hansmann
Publication date: Available online 13 June 2020Source: Dental MaterialsAuthor(s): Naoko Suzaki, Satoshi Yamaguchi, Nanako Hirose, Ryousuke Tanaka, Yusuke Takahashi, Satoshi Imazato, Mikako Hayashi
Publication date: Available online 11 June 2020Source: Dental MaterialsAuthor(s): Agron Hoxha, David G. Gillam, Amani Agha, Natalia Karpukhina, Andy J. Bushby, Mangala P. Patel
Publication date: Available online 11 June 2020Source: Dental MaterialsAuthor(s): Seung-Hoon Han, Yasushi Shimada, Alireza Sadr, Junji Tagami, Kee-Yeon Kum, Sung-Ho Park
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