Abstract High resolution computed tomography (HRCT) of temporal bone helps in understanding the complex anatomy of temporal bone and in identifying disease in temporal bone. However, its role in diagnosing cholesteatoma and analyzing its extent and complications is not established unequivocally. Present study was undertaken to check sensitivity and specificity of HRCT in diagnosing cholesteatoma and assessing its extent and in identifying ossicular destruction and other complications....
Wed Jun 10, 2020 03:00
Carmen Mascaró (a la izquierda) en clase práctica en la Universidad de Lurio (Nampula)Cuando nos hablan de parásitos una mezcla de repugnancia y fobia nos inunda la mente. Esto tiene dos explicaciones desde una perspectiva evolucionista, una de supervivencia individual y otra de supervivencia grupal. Por un lado, las especies parásitas toman y no dan nada a cambio. Y en el proceso puede suceder que nos hagan enfermar, disminuyendo nuestras probabilidades de sobrevivir y dejar descendencia viable....
Wed Jun 10, 2020 23:19
Factors associated with fatigue in breast cancer patients undergoing external beam radiation therapy
Publication date: Available online 9 June 2020Source: Practical Radiation OncologyAuthor(s): Michael J. LaRiviere, Hann-Hsiang Chao, Abigail Doucette, Timothy P. Kegelman, Neil K. Taunk, Gary M. Freedman, Neha Vapiwala
Wed Jun 10, 2020 23:00
Publication date: Available online 10 June 2020Source: NeuroImageAuthor(s): Joseph M. Gullett, Andrew O’Shea, Damon G. Lamb, Eric Porges, Deirdre M. O’Shea, Ofer Pasternak, Ronald Cohen, Adam J. Woods
Wed Jun 10, 2020 22:56
Publication date: Available online 10 June 2020Source: NeuroImageAuthor(s): Lukas A.W. Gemein, Robin T. Schirrmeister, Patryk Chrabąszcz, Daniel Wilson, Joschka Boedecker, Andreas Schulze-Bonhage, Frank Hutter, Tonio Ball
Wed Jun 10, 2020 22:56
Intestinal ischemia/reperfusion (I/R) injury often causes inflammatory responses and coagulation disorders, which is further promoting the deterioration of the disease. Hydrogen has anti-inflammatory, antioxidative, and antiapoptotic properties against various diseases. However, the effect of hydrogen on coagulation dysfunction after intestinal I/R and the underlying mechanism remains unclear. The purpose of this study was to explore whether hydrogen-rich solution (HRS) could attenuate coagulation...
Wed Jun 10, 2020 15:35
Purpose. Interleukin-1α (IL-1α) is a potent cytokine that plays a role in inflammatory arthritis and bone loss. Decoy receptor 3 (DCR3) is an immune modulator of monocytes and macrophages. The aim of this study was to investigate the mechanism of DCR3 in IL-1α-induced osteoclastogenesis. Methods. We treated murine macrophages with DCR3 during receptor activator of nuclear factor kappa Β ligand- (RANKL-) plus IL-1α-induced osteoclastogenesis to monitor osteoclast formation by tartrate-resistant acid...
Wed Jun 10, 2020 11:50
Publication date: Available online 10 June 2020Source: Journal of Cranio-Maxillofacial SurgeryAuthor(s): Lei-Hao Hu, Wen-Bo Zhang, Yao Yu, Xin Peng
Wed Jun 10, 2020 22:42
Abstract Purpose This study determined the frequency of adverse reactions related to the administration of local dental anesthesia with 4% articaine compared with 2% lidocaine, both associated with epinephrine 1:100,000. The null hypothesis was that there is no difference between the administrations of both dental local anesthesia. Methods From a total...
Wed Jun 10, 2020 03:00
Abstract Natural killer (NK) cells, a predominant innate lymphocyte subset, mediates eradicating malignant cells. Purinergic signaling by ectonucleotidase CD39 can suppress T-cell response in caner. However, the role of CD39 in NK cells has not been fully elucidated. Here, we characterized CD39 expression on NK cells and its clinical relevance in esophageal squamous cell carcinoma (ESCC). Peripheral blood and tissue samples were collected from 36 ESCC patients. We observed that...
Wed Jun 10, 2020 03:00
Wed Jun 10, 2020 03:00
Chemo-resistance of bladder cancer has been considered to be one of the serious issues to be solved. In this study, we revealed pivotal role of miR-424 in the regulation of CDDP sensitivity of bladder cancer c...
Wed Jun 10, 2020 03:00
Objectives/Hypothesis The ideal trachea replacement would be a living graft that is genetically identical to the host, avoiding the need for immunosuppression. We have developed a mouse model of syngeneic tracheal transplant that results in long‐term survival without graft stenosis or delayed healing. To understand how host cells contribute to tracheal transplant integration, we quantified the populations of host cells in the graft and native trachea following implant. Study Design: Tracheal transplant,...
Wed Jun 10, 2020 20:54
Publication date: Available online 10 June 2020Source: American Journal of OtolaryngologyAuthor(s): Nurullah Seyhun, Uğur Doğan, Zeynep Aslı Batur Çalış, Mehmet Fatih Kaya, Seyhan Özakkoyunlu Hasçiçek, Suat Turgut
Wed Jun 10, 2020 21:00
Omalizumab, mepolizumab, benralizumab, and dupilumab are the currently available biologics used to treat asthma in Japan. Anaphylaxis following treatment with mepolizumab or benralizumab is considered rare.
Wed Jun 10, 2020 03:00
Abstract Melanoma constitutes one of the most sinister and troublesome malignancies encountered by humanity. Generally, the diagnosis of advanced melanoma connotes a grave prognosis, prompting a sense of looming threat of death, however the early‐stage detected disease responds well to robust treatment resulting in reasonable survivorship. Scalp melanomas are even more troublesome, because they typically exhibit more aggressive biologic behavior and are often diagnosed at a late stage. This review...
Wed Jun 10, 2020 17:09
PD1/PDL1 inhibitors have been adopted for the treatment of advanced non-small-cell lung cancer, and PDL1 expression has been investigated as a predictive biomarker for PD1/PDL1 inhibitor therapy. However, PDL1 lacks diagnostic accuracy in differentiating patients who are likely or unlikely to benefit. So, it is urgent and clinically significant to identify other associated predictive biomarkers for PD1/PDL1 inhibitor therapy. Our work was to identify PDL1-related biomarkers that could improve the...
Wed Jun 10, 2020 09:50
In this study, we investigated the utility of pentraxin 3 (PTX-3) in bronchoalveolar lavage fluid (BALF) as lung cancer (LCa) diagnostic. A total of 89 LCa patients and 84 non-LCa patients who received bronchoscopy in the First Affiliated Hospital of Xi’an Jiaotong University from December 2014 to February 2015 were enrolled. LCa was subdivided according to pathological type (scale, gland, and small cell lung cancer). BALF samples were obtained during bronchoscopy and PTX-3 levels assayed by ELISA....
Wed Jun 10, 2020 09:50
AbstractThe management of bladder exstrophy (BE) remains one of the most significant challenges encountered by pediatric urologists despite improvements in the operative techniques worldwide. Regardless of surgical technique, timing of primary closure remains a matter of debate. The initial closure may be performed within the first 48–72 hours of life or at ~6–12 weeks of age. Delayed presentation until adolescence is extremely rare. However, due to lack of awareness, and access to healthcare along...
Wed Jun 10, 2020 03:00
Publication date: Available online 10 June 2020Source: Clinical ImagingAuthor(s): Nimai Patel, Hubert Swana, Craig Johnson
Wed Jun 10, 2020 20:46
Publication date: Available online 10 June 2020Source: Clinical ImagingAuthor(s): Laura Maria Minordi, Luigi Larosa, Alfredo Papa, Giovanni Cimino, Antonio Bevere, Maria Gabriella Brizi, Riccardo Manfredi
Wed Jun 10, 2020 20:46
Publication date: Available online 10 June 2020Source: Clinical ImagingAuthor(s): Mona P. Tan, Zhen Bi, Eugene M.W. Ong
Wed Jun 10, 2020 20:46
Publication date: Available online 10 June 2020Source: Clinical ImagingAuthor(s): Dipan Danda, Jonathan Mezrich
Wed Jun 10, 2020 20:46
Publication date: Available online 9 June 2020Source: Clinical ImagingAuthor(s): Sanaz Katal, Leila Aghaghazvini, Ali Gholamrezanezhad
Wed Jun 10, 2020 20:46
Publication date: Available online 9 June 2020Source: Clinical ImagingAuthor(s): Laura Evangelista, Ilaria Ravelli, Antonio Bignotto, Diego Cecchin, Pietro Zucchetta
Wed Jun 10, 2020 20:46
Publication date: Available online 10 June 2020Source: Acta Otorrinolaringológica EspañolaAuthor(s): Eulalia Porras Alonso, Isabel Vilaseca González, Miguel García Teno, Rafael Barberá Durbán, Guillem Viscasillas Pallàs, Manuela Sancho Mestre, Juan Rebollo Otal, Alicia Menoyo Bueno, Pedro Díaz de Cerio Canduela
Wed Jun 10, 2020 20:46
Publication date: Available online 9 June 2020Source: Medical HypothesesAuthor(s): Anshika Chauhan, Sushmita Ghoshal, Arnab Pal
Wed Jun 10, 2020 20:40
Publication date: Available online 9 June 2020Source: Medical HypothesesAuthor(s): Vittorio Unfer, Gianpiero Forte
Wed Jun 10, 2020 20:40
Publication date: Available online 9 June 2020Source: Medical HypothesesAuthor(s): Paul J. Fitzgerald
Wed Jun 10, 2020 20:40
Publication date: Available online 9 June 2020Source: Medical HypothesesAuthor(s): Valente Maldonado, Loza-Mejía, Jaime Chávez Alderete
Wed Jun 10, 2020 20:40
Publication date: Available online 9 June 2020Source: Medical HypothesesAuthor(s): Andrew N. Glushkov, Elena G. Polenok, Stella A. Mun, Lyudmila A. Gordeeva
Wed Jun 10, 2020 20:40
Abstract Purpose The current gold standard for diagnosis of obstructive sleep apnea (OSA) is overnight in laboratory polysomnography (PSG). However, PSGs are expensive, labor-intensive, and have long wait times. An ambulatory sleep study device, the WatchPAT, has been shown to have high correlation for sleep indices measured compared with PSG (AASM, 2016). Use of the WatchPAT could potentially lead to shorter waiting times and earlier...
Wed Jun 10, 2020 03:00
Abstract Objectives The study aimed to evaluate the diagnostic value of an original questionnaire for obstructive sleep apnea (OSA), the BOAH scale, and its ability to prioritize patients at high risk for OSA for polysomnography (PSG) examination. Methods The analysis included 273 patients referred to the Department of Sleep Medicine of the Royal Infirmary,...
Wed Jun 10, 2020 03:00
Publication date: 1 July 2020Source: International Journal of Radiation Oncology*Biology*Physics, Volume 107, Issue 3Author(s):
Wed Jun 10, 2020 20:31
Publication date: 1 July 2020Source: International Journal of Radiation Oncology*Biology*Physics, Volume 107, Issue 3Author(s):
Wed Jun 10, 2020 20:31
Publication date: 1 July 2020Source: International Journal of Radiation Oncology*Biology*Physics, Volume 107, Issue 3Author(s): Susan Y. Wu, Steve E. Braunstein
Wed Jun 10, 2020 20:31
Publication date: 1 July 2020Source: International Journal of Radiation Oncology*Biology*Physics, Volume 107, Issue 3Author(s): John Leung
Wed Jun 10, 2020 20:31
Publication date: 1 July 2020Source: International Journal of Radiation Oncology*Biology*Physics, Volume 107, Issue 3Author(s): Vérane Achard, Pelagia Tsoutsou, Thomas Zilli
Wed Jun 10, 2020 20:31
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