LK Prashanth, R Jayachandran, S Ragavendra, Rajesh B IyerAnnals of Indian Academy of Neurology 2020 23(3):363-364
Wed Jun 10, 2020 00:00
Maneesh Shakywar, Kanchana Pillai, Rajesh Kumar Singh, Anuj Prabhakar, Deepa Dash, Rohit Bhatia, Manjari TripathiAnnals of Indian Academy of Neurology 2020 23(3):417-418
Wed Jun 10, 2020 00:00
Boby Varkey MaramattomAnnals of Indian Academy of Neurology 2020 23(3):364-365
Wed Jun 10, 2020 00:00
Neeharika L Mathukumali, Swetha R Tandra, Sireesha Yareeda, Rukmini M Kandadai, Padmaja Gaddamanugu, Suryaprabha Turaga, Shaik A Jabeen, Rupam BorgohainAnnals of Indian Academy of Neurology 2020 23(3):422-423
Wed Jun 10, 2020 00:00
02:01
Maternally transmitted Wolbachia bacteria infect about half of all insect species. They usually show imperfect maternal transmission and often produce cytoplasmic incompatibility (CI). Irrespective of CI, Wolbachia frequencies tend to increase when rare only if they benefit host fitness. Several Wolbachia, including wMel that infects Drosophila melanogaster cause weak or no CI and persist at intermediate frequencies. On the island of Sao Tome off West Africa, the frequencies of wMel-like Wolbachia...
Wed Jun 10, 2020 03:00
The mining bee subfamily Andreninae (Hymenoptera: Andrenidae) is a widely distributed and diverse group of ground-nesting solitary bees, including numerous species known as important pollinators. Most of the species diversity of Andreninae is concentrated in the mainly Holarctic genus Andrena, comprising ca. 1500 described species. The subfamily and especially the genus have remained relatively neglected by recent molecular phylogenetic studies, with current classifications relying largely on morphological...
Wed Jun 10, 2020 03:00
Chitinases enzymatically hydrolyze chitin, a highly abundant biomolecule with many potential industrial and medical uses in addition to their natural biological roles. Fungi are a rich source of chitinases, however the phylogenetic and functional diversity of fungal chitinases are not well understood. We surveyed fungal chitinases from 373 publicly available genomes, characterized domain architecture, and conducted phylogenetic analyses of the glycoside hydrolase family 18 (GH18) domain. This large-scale...
Wed Jun 10, 2020 03:00
Highly divergent sites in multiple sequence alignments, which stem from erroneous inference of homology and saturation of substitutions, are thought to negatively impact phylogenetic inference. Trimming methods aim to remove these sites before phylogenetic inference, but recent analysis suggests that doing so can worsen inference. We introduce ClipKIT, a trimming method that instead aims to retain phylogenetically-informative sites; phylogenetic inference using ClipKIT-trimmed alignments is accurate,...
Wed Jun 10, 2020 03:00
There is no satisfactory explanation for why peacock possesses a tail, presence and especially courtship display of which makes the organism vulnerable to predation. Here, I present a model according to which in a polygynous mating system a mechanism which increases vulnerability to predation, a Zahavian handicap, evolves when other two mechanisms to identify high-quality males are either absent or are not sufficiently strong. The two mechanisms are: 1) male resource acquisition ability, and 2) male-male...
Wed Jun 10, 2020 03:00
It is generally believed that when maternally inherited sex ratio distorters become predominant, either the host population goes extinct or nuclear suppressors evolve in the host. Here, we show an empirical case where all-female-producing Wolbachia is likely to be stably maintained at a high frequency. On an island population of the butterfly Eurema mandarina, a Wolbachia strain wFem, which makes female hosts produce all-female offspring without sibling lethality (female drive), is highly prevalent....
Wed Jun 10, 2020 03:00
Hybridization between species can affect the strength of the reproductive barriers that separate those species. Two extensions of this effect are: (1) the expectation that asymmetric hybridization will have asymmetric effects on reproductive barrier strength and (2) the expectation that local hybridization will affect only local reproductive barrier strength and could therefore alter within-species compatibility. We tested these hypotheses in a pair of morning glory species that exhibit asymmetric...
Wed Jun 10, 2020 03:00
MicroRNA target sites are often conserved during evolution and purifying selection to maintain such sites is expected. On the other hand, comparative analyses identified a paucity of microRNA target sites in co-expressed transcripts, and novel target sites can potentially be deleterious. We proposed that selection against novel target sites pervasive. The analysis of derived allele frequencies revealed that, when the derived allele is a target site, the proportion of non-target sites is higher than...
Tue Jun 09, 2020 03:00
[ASAP] Correction to Efficient Targeted Degradation via Reversible and Irreversible Covalent PROTACs
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c05753
Wed Jun 10, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c05666
Wed Jun 10, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c03949
Wed Jun 10, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c04674
Wed Jun 10, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c05698
Wed Jun 10, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c03298
Wed Jun 10, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c06189
Wed Jun 10, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c02009
Wed Jun 10, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c03177
Wed Jun 10, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c00531
Wed Jun 10, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.9b13652
Wed Jun 10, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c03527
Wed Jun 10, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c02287
Wed Jun 10, 2020 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.0c01125
Wed Jun 10, 2020 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.0c01291
Wed Jun 10, 2020 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.0c01734
Wed Jun 10, 2020 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.9b05826
Wed Jun 10, 2020 07:00
Laryngo-Rhino-Otologie 2020; S 02Article in Thieme eJournals:Table of contents | Congress
Wed Jun 10, 2020 02:00
Laryngorhinootologie 2020; 99: S2-S2DOI: 10.1055/s-0040-1712186© Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents | open access Full text
Wed Jun 10, 2020 02:00
LaryngorhinootologieDOI: 10.1055/a-1183-4835Nachdem anfängliche Berichte über die SARS-CoV-2-Infektion Riech- und Schmeckstörungen kaum erwähnten, haben mittlerweile mehrere Studien, insbesondere aus Europa und den USA, diese Symptome als Merkmal von COVID-19 bestätigt. Gut 2 Drittel der Erkrankten scheinen im Verlauf der Erkrankung eine Riech- und Schmeckminderung zu erleiden, wobei die meisten der bislang veröffentlichten Studien auf Fragebögen und anamnestischen Daten basieren. Validierte Riechtests...
Wed Jun 10, 2020 02:00
Laryngorhinootologie 2020; 99: S2-S2DOI: 10.1055/s-0040-1713566© Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents | open access Full text
Wed Jun 10, 2020 02:00
Opercular syndrome, also known as Foix-Chavany-Marie syndrome, is a paralysis of the facial, pharyngeal, masticatory, tongue, laryngeal, and brachial muscles. It is a rare cortical form of pseudobulbar palsies caused by vascular insults to bilateral operculum.
V Abhinay S. K Reddy, Gaurav K Mittal, Shilpa Sekhar, Jennifer Singhdev, Rakesh MishraAnnals of Indian Academy of Neurology 2020 23(3):405-407
Wed Jun 10, 2020 00:00
Arunmozhimaran Elavarasi, Vinay GoyalAnnals of Indian Academy of Neurology 2020 23(3):360-361
Wed Jun 10, 2020 00:00
Lauren E Ryden, Elie Matar, Jennifer Y. Y Szeto, Deborah A Hammond, Paul Clouston, Simon J. G LewisAnnals of Indian Academy of Neurology 2020 23(3):409-411
Wed Jun 10, 2020 00:00
Pranav Ish, Kirti Sachdev, Sumita Agrawal, Nitesh GuptaAnnals of Indian Academy of Neurology 2020 23(3):361-362
Wed Jun 10, 2020 00:00
Divya M Radhakrishnan, Ramanuj Samanta, Rajat Manchanda, Sweety Kumari, Ritu Shree, Niraj KumarAnnals of Indian Academy of Neurology 2020 23(3):413-415
Wed Jun 10, 2020 00:00
Shoko Merrit Yamada, Shinnosuke Takashima, Yoshiro Takaoka, Hiroshi MatsuuraAnnals of Indian Academy of Neurology 2020 23(3):344-347 Objective: Onabotulinum toxin A (botulinum A toxin) is utilized to extend flexed extremities in spastic hemiparesis. Injection points are important to obtain a better effect. Injecting botulinum A toxin into the forearm muscles is a standard method for flexed wrist and fingers; however, we developed new injection points in the intrinsic muscles of the hand to acquire...
Wed Jun 10, 2020 00:00
Ramesh Aggarwal, Divyani Garg, Rajinder K DhamijaAnnals of Indian Academy of Neurology 2020 23(3):383-384
Wed Jun 10, 2020 00:00
Vinu Narayan, Sunita Bijarnia Mahay, Ishwar Chander Verma, Ratna Dua PuriAnnals of Indian Academy of Neurology 2020 23(3):347-351 Guanidinoacetate methyltransferase (GAMT) deficiency is the second most common defect in the creatine metabolism pathway resulting in cerebral creatine deficiency syndrome (CCDS). We report three patients from two unrelated families, diagnosed with GAMT deficiency on next-generation sequencing. All the probands had happy predisposition as a predominant manifestation...
Wed Jun 10, 2020 00:00
Bhanudeep Singanamalla, Shivan Kesavan, Arushi G SainiAnnals of Indian Academy of Neurology 2020 23(3):386-387
Wed Jun 10, 2020 00:00
Suresh Kumar, Shikha Bhatia, Mukesh Surya, Sanjiv SharmaAnnals of Indian Academy of Neurology 2020 23(3):352-354 L-2 Hydroxyglutaric aciduria is a rare metabolic disorder which is autosomal recessive in inheritance. It is characterised by the increased urinary excretion of L-2 hydroxyglutaric acid and the diagnosis is based on the increased levels of the L-2 hydroxy glutaric acid in the urine, serum & CSF. This is a neurometabolic disorder which is associated with slowly progressive psychomotor...
Wed Jun 10, 2020 00:00
Karanvir, Divyani Garg, Suvasini Sharma, Sanjay PandeyAnnals of Indian Academy of Neurology 2020 23(3):389-390
Wed Jun 10, 2020 00:00
Boby Varkey MaramattomAnnals of Indian Academy of Neurology 2020 23(3):355-355
Wed Jun 10, 2020 00:00
Anu Alex, Anjali Lepcha, Ann M Augustine, Ajay PhilipAnnals of Indian Academy of Neurology 2020 23(3):393-395
Wed Jun 10, 2020 00:00
Suman Kushwaha, Akhila Kumar Panda, Aldrin Anthony, Sandeep Singh, Dyutima Madan, Siddharth MaheshwariAnnals of Indian Academy of Neurology 2020 23(3):356-356
Wed Jun 10, 2020 00:00
Indar K Sharawat, Ananthanarayanan Kasinathan, Renu Suthar, Naveen SankhyanAnnals of Indian Academy of Neurology 2020 23(3):397-398
Wed Jun 10, 2020 00:00
Ajith CherianAnnals of Indian Academy of Neurology 2020 23(3):357-357
Wed Jun 10, 2020 00:00
Arzu Ekici, lyas Yilmaz, Orhan Görükmez, Cengiz Gökhan Orcan, Sevil DorumAnnals of Indian Academy of Neurology 2020 23(3):401-403
Wed Jun 10, 2020 00:00
Arushi G Saini, Renu SutharAnnals of Indian Academy of Neurology 2020 23(3):358-359
Wed Jun 10, 2020 00:00
Cancer Biotherapy and Radiopharmaceuticals, Ahead of Print.
Tue Jun 09, 2020 10:00
Cancer Biotherapy and Radiopharmaceuticals, Ahead of Print.
Tue Jun 09, 2020 10:00
Cancer Biotherapy and Radiopharmaceuticals, Ahead of Print.
Tue Jun 09, 2020 10:00
Pediatric Allergy, Immunology, and Pulmonology, Ahead of Print.
Tue Jun 09, 2020 10:00
Zacharias Lithin, Priya T Thomas, G Manjusha Warrier, Adhin Bhaskar, Saraswathi Nashi, Seena Vengalil, Kiran Polavarapu, Preethish Kumar, Ravi Yadav, Suvarna Alladi, Nalini Atchayaram, Pramod K PalAnnals of Indian Academy of Neurology 2020 23(3):313-317 Background and Aims: Palliative care is an important area of intervention in neurodegenerative diseases. The aim of this study is to understand the relationship between Palliative Care Needs and Caregiver Burden among persons diagnosed with neurodegenerative...
Wed Jun 10, 2020 00:00
Sangeetha Yoganathan, Gautham Arunachal, Lisa Kratz, Mugil Varman, Sniya Valsa Sudhakar, Samuel Philip Oommen, Shikha Jain, Maya Thomas, Manimegalai BabujiAnnals of Indian Academy of Neurology 2020 23(3):419-421
Wed Jun 10, 2020 00:00
Rohit Bhatia, M V. Padma SrivastavaAnnals of Indian Academy of Neurology 2020 23(3):318-324 Stroke is a serious neurological complication observed during the ongoing COVID-19 (coronavirus associated disease 2019) pandemic caused by SARS-CoV-2 (severe acute respiratory syndrome, corona virus 2) and includes both ischemic stroke and intracerebral haemorrhage. We reviewed factors that could potentially contribute to the occurrence of stroke among patients with COVID-19. There could be an interaction...
Wed Jun 10, 2020 00:00
Josef FinstererAnnals of Indian Academy of Neurology 2020 23(3):365-366
Wed Jun 10, 2020 00:00
Vishal Sondhi, Suvasini SharmaAnnals of Indian Academy of Neurology 2020 23(3):325-331 Movement disorders in childhood comprise a heterogeneous group of conditions that lead to impairment of voluntary movement, abnormal postures, or inserted involuntary movements. Movement disorders in children are frequently caused by metabolic disorders, both inherited and acquired. Many of these respond to vitamin supplementation. Examples include infantile tremor syndrome, biotinidase deficiency, biotin-thiamine-responsive...
Wed Jun 10, 2020 00:00
Harsh V Gupta, Abhishek LenkaAnnals of Indian Academy of Neurology 2020 23(3):368-369
Wed Jun 10, 2020 00:00
Arushi Gahlot Saini, Suvasini SharmaAnnals of Indian Academy of Neurology 2020 23(3):332-337 Movement disorders are one of the important neurological manifestations of inherited metabolic disorders. Important clues to the presence of an underlying inborn error of metabolism are early onset, presence of neuroregression or degeneration, parental consanguinity, sibling affection, paroxysmal events, waxing and waning course, skin or hair changes, absence of a perinatal insult or any structural cause,...
Wed Jun 10, 2020 00:00
Harsh V Gupta, Steven Swank, Vibhash D SharmaAnnals of Indian Academy of Neurology 2020 23(3):372-374
Wed Jun 10, 2020 00:00
Medha Tandon, Faiz M. H Ahmad, Subramanian Narayanan, Charu Mohan, Simone YadavAnnals of Indian Academy of Neurology 2020 23(3):338-341 Background: Parkinson's disease (PD) is the second-most common neurodegenerative disorder known primarily by its motor symptomatology. These motor manifestations are also hypothesised to affect the respiratory muscular function of PD patients contributing to restrictive pattern of ventilatory dysfunction. Previous reports attempting to detect these abnormalities...
Wed Jun 10, 2020 00:00
Rajinder K Dhamija, Achal K Srivastava, Divyani GargAnnals of Indian Academy of Neurology 2020 23(3):377-378
Wed Jun 10, 2020 00:00
Boby Varkey Maramattom, Nibu Dominic, Surya JosephAnnals of Indian Academy of Neurology 2020 23(3):342-344 Thyroid storm (TS) is a rare hyperthyroidism associated multisystem decompensation and can mimic a systemic inflammatory response syndrome. It is diagnosed in the presence of fever with cardiovascular, central nervous system, and gastrointestinal complications. Only a few reports of acute flaccid quadriplegic thyrotoxic myopathy (TM) with TS have been reported. However, muscle magnetic resonance...
Wed Jun 10, 2020 00:00
Leema P Cornelius, Vivekasaravanan Raju, Asir JulinAnnals of Indian Academy of Neurology 2020 23(3):380-381
Wed Jun 10, 2020 00:00
Shoko Merrit Yamada, Shinnosuke Takashima, Yoshiro Takaoka, Hiroshi MatsuuraAnnals of Indian Academy of Neurology 2020 23(3):344-347 Objective: Onabotulinum toxin A (botulinum A toxin) is utilized to extend flexed extremities in spastic hemiparesis. Injection points are important to obtain a better effect. Injecting botulinum A toxin into the forearm muscles is a standard method for flexed wrist and fingers; however, we developed new injection points in the intrinsic muscles of the hand to acquire...
Wed Jun 10, 2020 00:00
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