Mixed tumor of the skin (MTS) is a rare skin adnexal neoplasm occurring in sweat glands. It is usually benign, measures 0.5 to 3 cm, and presents as a slowly growing, painless, firm nodule commonly in the head and neck regions. Owing to its rarity and lack of distinctive clinical manifestations, confirmative diagnosis is made on the basis of its pathologic features. Malignant MTS also develops de novo or from preexisting benign MTS even though they occur rarely. It should be excised completely to...
Mon Jun 08, 2020 03:00
The present study is based on the concept of neuro-aging and how it may affect surrounding skin cells. It has been shown that many factors play a significant role in skin homeostasis by interfering with various cytokines, either through activation or inhibition. Granulocyte macrophage colony-stimulating factor (GM-CSF) is generally recognized as an inflammatory cytokine, and our previous study has shown its effects on neuronal senescence after ultraviolet (UV) irradiation of skin cells. Following...
Mon Jun 08, 2020 03:00
Recently, a technical note describing a promising method for the management of infections after sinus bone grafting by irrigating the corresponding area with hydrogen peroxide based solution with an aid of a drain has been published. The aim of this paper was to present the histological and radiological results of the above mentioned technique. A total of 17 patients who have presented with infections secondary to sinus bone grafting enrolled in the study. During implant placement, bone was collected...
Mon Jun 08, 2020 03:00
Abstract The EFSA Panel on Food Contact Materials, Enzymes and Processing Aids (CEP ) was requested by the European Commission to review the substances for which a Specific Migration Limit (SML ) is not assigned in Regulation (EU ) No 10/2011. These substances had been covered by the Generic SML of 60 mg/kg food, but with Regulation (EU ) 2016/1416 it was removed, necessitating their re‐examination. EFSA was requested to identify those substances requiring an SML to ensure the authorisation...
Wed Jun 10, 2020 12:47
Abstract EFSA received from the European Commission a mandate to deliver a reasoned opinion according to Article 43 of Regulation (EC ) No 396/2005 on the safety of a proposed temporary maximum residue level (tMRL ) for chlorpropham in potatoes to consumers. Sprout inhibitors based on the active substance chlorpropham have been widely used in commercial storage facilities in Europe over multiple seasons. Following the non‐renewal of approval of chlorpropham, representatives of potato trade organisations...
Wed Jun 10, 2020 12:47
Abstract Following a request from the European Commission, the Panel on Additives and Products or substances used in Animal Feed (FEEDAP ) was asked to deliver a scientific opinion on l ‐tryptophan produced by fermentation with Escherichia coli CGMCC 11674 when used as a nutritional additive in feed and water for drinking for all animal species and categories. The FEEDAP Panel issued an opinion in 2019 in which they could not conclude on the safety of the additive for the target animals and for...
Wed Jun 10, 2020 11:30
Abstract The Panel on Food Additives and Flavourings (FAF ) provided a scientific opinion re‐evaluating the safety of Sodium aluminium silicate (E 554) and potassium aluminium silicate (E 555) as food additives. The Scientific Committee for Food (SCF ) assigned these food additives together with other aluminium‐containing food additives a provisional tolerable weekly intake (PTWI ) of 7 mg aluminium/kg body weight (bw). In 2008, EFSA established a tolerable weekly intake (TWI ) of 1 mg aluminium/kg...
Wed Jun 10, 2020 11:23
Abstract The EFSA Panel on Food Additives and Flavourings was requested to evaluate 49 flavouring substances assigned to the Flavouring Group Evaluation 91 (FGE .91), using the Procedure as outlined in the Commission Regulation (EC ) No 1565/2000. Forty‐four substances have been considered in FGE .91 and its revisions (FGE .91Rev1 and FEG .91Rev2). With regard to the remaining five flavouring substances considered in this revision 3 of FGE .91: two ([FL ‐no: 12.065 and 12.079]) have been cleared...
Wed Jun 10, 2020 11:06
Abstract Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP ) was asked to deliver a scientific opinion on the safety for the environment and efficacy of DSP ® (a mixture of disodium salt of ethylenediaminetetraacetic acid (Na2EDTA ), tannin‐rich extract of Castanea sativa , thyme oil and origanum oil) as a zootechnical feed additive for pigs for fattening. The European Commission request followed an inconclusive opinion...
Wed Jun 10, 2020 11:04
Related ArticlesAn improved clear cell renal cell carcinoma stage prediction model based on gene sets. BMC Bioinformatics. 2020 Jun 08;21(1):232 Authors: Li F, Yang M, Li Y, Zhang M, Wang W, Yuan D, Tang D Abstract BACKGROUND: Clear cell renal cell carcinoma (ccRCC) is the most common subtype of renal cell carcinoma and accounts for cancer-related deaths. Survival rates are very low when the tumor is discovered in the late-stage. Thus, developing an...
Wed Jun 10, 2020 13:56
Related ArticlesPVAmpliconFinder: a workflow for the identification of human papillomaviruses from high-throughput amplicon sequencing. BMC Bioinformatics. 2020 Jun 08;21(1):233 Authors: Robitaille A, Brancaccio RN, Dutta S, Rollison DE, Leja M, Fischer N, Grundhoff A, Gheit T, Tommasino M, Olivier M Abstract BACKGROUND: The detection of known human papillomaviruses (PVs) from targeted wet-lab approaches has traditionally used PCR-based methods coupled...
Wed Jun 10, 2020 13:56
Publication date: Available online 10 June 2020Source: Journal of Oral and Maxillofacial SurgeryAuthor(s): Huseyin Can Tukel, Yusuf Kenan Daglioglu, Ufuk Tatli, Leman Sencar Gundogdu, Mehmet Kurkcu, Mehmet Emre Benlidayi
Wed Jun 10, 2020 13:54
Publication date: Available online 10 June 2020Source: Journal of Oral and Maxillofacial SurgeryAuthor(s): Omar Kholaki, David Metter, Rahul Tandon, Thomas Schlieve
Wed Jun 10, 2020 13:54
Publication date: Available online 10 June 2020Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): Jessica Stern, Michael Chen, Todd A. Jusko, Maria Fagnano, Kirsi M. Järvinen, Jill S. Halterman
Wed Jun 10, 2020 13:53
Publication date: July 2020Source: Acta Histochemica, Volume 122, Issue 5Author(s): Kei-ichiro Uemura, Tokumasa Hayashi, Tasuku Hiroshige, Kosuke Ueda, Keisuke Ohta, Tomonoshin Kanazawa, Shingo Hirashima, Makoto Nakiri, Tsukasa Igawa, Kei-ichiro Nakamura
Wed Jun 10, 2020 13:52
Publication date: Available online 10 June 2020Source: International Journal of Oral and Maxillofacial SurgeryAuthor(s): Y. Zou, F.S. Xue, S.H. Liu, H.J. Hou
Wed Jun 10, 2020 13:49
Publication date: June 2020Source: International Journal of Oral and Maxillofacial Surgery, Volume 49, Issue 6Author(s):
Wed Jun 10, 2020 13:49
Nature Communications, Published online: 10 June 2020; doi:10.1038/s41467-020-16731-6CRISPR technology is emerging as a potential antimicrobial against antimicrobial-resistant bacteria. Here the authors develop a bacteriophage delivered Cas13a system for killing target bacteria and detecting bacterial genes.
Wed Jun 10, 2020 03:00
Nature Communications, Published online: 10 June 2020; doi:10.1038/s41467-020-16333-2Deep tissue imaging has been limited by the low brightness of probes emitting in the second near-infrared window. Here, the authors use femtosecond laser irradiation to grow a protective shell on Ag2S nanoparticles, achieving 80-fold quantum yield enhancement and imaging with low excitation intensities.
Wed Jun 10, 2020 03:00
Nature Communications, Published online: 10 June 2020; doi:10.1038/s41467-020-16769-6Electrochemical water splitting is an attractive energy conversion technology, but it usually suffers from low efficiency. Here, the authors report intermetallic Co3Mo integrated on porous Cu as highly efficient electrocatalysts for alkaline HER/OER due to in-situ hydroxylation and electro-oxidation.
Wed Jun 10, 2020 03:00
Nature Communications, Published online: 10 June 2020; doi:10.1038/s41467-020-16844-yOptical transitions between Landau levels (LL) in solids are described by selection rules associated with the LL index. Here, the authors perform photocurrent spectroscopy measurements on high-quality bilayer graphene to investigate the interband LL transitions, and observe valley-dependent optical transitions obeying unusual selection rules.
Wed Jun 10, 2020 03:00
Nature Communications, Published online: 10 June 2020; doi:10.1038/s41467-020-16804-6Changes in osmotic homeostasis alter metabolites and therefore chemical milieu of the cells. Here, the authors show that altering metabolites in E. coli also change the cellular capacity for buffering mutations that impair protein folding and influences proteostasis irrespective of molecular chaperones
Wed Jun 10, 2020 03:00
Nature Communications, Published online: 10 June 2020; doi:10.1038/s41467-020-16748-xCarbon atoms of various species typically function as acceptors of noncovalent interactions when they are part of a π-system. Here, the authors report their discovery of a noncovalent halogen bond involving the isocyano carbon lone pair, which results in adducts with strongly reduced isocyanide odor.
Wed Jun 10, 2020 03:00
Nature Communications, Published online: 10 June 2020; doi:10.1038/s41467-020-16314-5Author Correction: NADH oxidase-dependent CD39 expression by CD8+ T cells modulates interferon gamma responses via generation of adenosine
Wed Jun 10, 2020 03:00
Nature Communications, Published online: 10 June 2020; doi:10.1038/s41467-020-16779-4Amid the COVID-19 pandemic, scientists around the globe have been working resolutely to find therapies to treat patients and avert the spreading of the SARS-CoV-2 virus. In this commentary, we highlight some of the latest studies that provide atomic-resolution structural details imperative for the development of vaccines and antiviral therapeutics.
Wed Jun 10, 2020 03:00
Wed Jun 10, 2020 03:00
Wed Jun 10, 2020 03:00
Wed Jun 10, 2020 03:00
Wed Jun 10, 2020 03:00
Wed Jun 10, 2020 03:00
Wed Jun 10, 2020 03:00
Wed Jun 10, 2020 03:00
Publication date: Available online 9 June 2020Source: Auris Nasus LarynxAuthor(s): Yun Jin Kang, Jin Hee Cho, Min Hyeong Lee, Yeon Ji Kim, Chan-Soon Park
Wed Jun 10, 2020 13:47
Abstract ABBV-176 is an antibody-drug conjugate composed of the humanized antibody h16f (PR-1594804) conjugated to a highly potent, cytotoxic cross-linking pyrrolobenzodiazepine dimer (PBD; SGD-1882) targeting the prolactin receptor (PRLR), which is overexpressed in several solid tumor types. This phase 1, dose-escalation study (NCT03145909) evaluated the safety, pharmacokinetics, and preliminary activity of ABBV-176 in patients with advanced solid tumors likely to exhibit elevated...
Wed Jun 10, 2020 03:00
Publication date: Available online 10 June 2020Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Brittany L. Willer, Arlyne K. Thung, Marco Corridore, Ajay J. D’Mello, Brian S. Schloss, Prashant S. Malhotra, Patrick C. Walz, Charles A. Elmaraghy, Joseph D. Tobias, Kris R. Jatana, Vidya T. Raman
Wed Jun 10, 2020 13:46
Related ArticlesThe Role of Temporal and Spatial Attention in Size Adaptation. Front Neurosci. 2020 Jun 03;14:539 Authors: Tonelli A, Pooresmaeili A, Arrighi R Abstract One of the most important tasks for the visual system is to construct an internal representation of the spatial properties of objects, including their size. Size perception includes a combination of bottom-up (retinal inputs) and top-down (e.g., expectations) information, which makes...
Wed Jun 10, 2020 13:45
Publication date: Available online 9 June 2020Source: Journal of the American College of SurgeonsAuthor(s): Mark J. Kulbaski
Wed Jun 10, 2020 13:44
Related ArticlesEmerging Molecular Targets for the Management of Cancer Pain. Neurosci Bull. 2020 Jun 08;: Authors: Sheng HY, Zhang YQ PMID: 32514879 [PubMed - as supplied by publisher]
Wed Jun 10, 2020 13:43
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου