In depth evolutionary and structural analyses of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) isolated from bats, pangolins, and humans are necessary to assess the role of natural selection and recombination in the emergence of the current pandemic strain. The SARS-CoV-2 S glycoprotein unique features have been associated with efficient viral spread in the human population. Phylogeny-based and genetic algorithm methods clearly show that recombination events between viral progenitors...
Wed Jun 10, 2020 03:00
Related ArticlesVascular endothelial growth factor (VEGF) and Endocrine gland-VEGF (EG-VEGF) are down regulated in head and neck cancer. Clin Otolaryngol. 2020 Jun 09;: Authors: Bouzoubaa M, Benlahfid M, Sidqui M, Aboussaouira T, Rifki C, Brouillet S, Traboulsi W, Alfaidy N, Benharouga M Abstract OBJECTIVE: To characterize the role of VEGF, EG-VEGF and its receptors in the developmentand progression of HNC. DESIGN: Human serumand tissues...
Wed Jun 10, 2020 14:25
Related ArticlesGiant Mixed Tumor of the Skin Affecting the Hemiface. J Craniofac Surg. 2020 Jun 08;: Authors: Sung KY, Lee SK, Jeong YJ, Lee SY Abstract Mixed tumor of the skin (MTS) is a rare skin adnexal neoplasm occurring in sweat glands. It is usually benign, measures 0.5 to 3 cm, and presents as a slowly growing, painless, firm nodule commonly in the head and neck regions. Owing to its rarity and lack of distinctive clinical manifestations,...
Wed Jun 10, 2020 14:25
Related ArticlesPersistent Unilateral Middle Ear Effusion Caused by a Parapharyngeal Space Mass in an Adult. Ear Nose Throat J. 2020 Jun 09;:145561320929177 Authors: Kuo CY, Lee CC, Wang CH PMID: 32516004 [PubMed - as supplied by publisher]
Wed Jun 10, 2020 14:25
Related ArticlesAssociation Among Glucocorticoid Receptor Sensitivity, Fatigue, and Inflammation in Patients With Head and Neck Cancer. Psychosom Med. 2020 Jun;82(5):508-516 Authors: Xiao C, Eldridge RC, Beitler JJ, Higgins KA, Chico CE, Felger JC, Wommack EC, Knobf T, Saba NF, Shin DM, Bruner DW, Miller AH Abstract OBJECTIVE: Fatigued cancer patients often have high peripheral inflammation; however, the biological mechanisms of this association...
Wed Jun 10, 2020 14:25
Related ArticlesEpidemiological analysis of patients with burns in third-line hospitals in Turkey. Int Wound J. 2020 Jun 09;: Authors: Bahçe ZŞ, Öztaş T Abstract Burns are a major health problem worldwide. Burn injury resulting from making contact with hot objects, direct or indirect contact with flame, and exposure to chemical agents or electric current is usually preventable. In this study, epidemiological data of the patients who had been hospitalised...
Wed Jun 10, 2020 14:25
Related ArticlesImpact of the COVID-19 Global Pandemic on the Otolaryngology Fellowship Application Process. Otolaryngol Head Neck Surg. 2020 Jun 09;:194599820934370 Authors: Nesemeier BR, Lebo NL, Schmalbach CE, Barnes KJ, Vernon D, Ting JY, Shipchandler TZ Abstract On March 11, 2020, the World Health Organization declared coronavirus disease 2019 a global pandemic. In addition to massive social disruption, this pandemic affected the traditional...
Wed Jun 10, 2020 14:25
Related ArticlesA Multimodal Multi-Institutional Solution to Remote Medical Student Education for Otolaryngology During COVID-19. Otolaryngol Head Neck Surg. 2020 Jun 09;:194599820933599 Authors: Ruthberg JS, Quereshy HA, Ahmadmehrabi S, Trudeau S, Chaudry E, Hair B, Kominsky A, Otteson TD, Bryson PC, Mowry SE Abstract During the coronavirus 2019 pandemic, there has been a surge in production of remote learning materials for continued otolaryngology...
Wed Jun 10, 2020 14:25
Related ArticlesProphylactic and Therapeutic Effects of Curcumin on Treatment-Induced Oral Mucositis in Patients with Head and Neck Cancer: A Meta-Analysis of Randomized Controlled Trials. Nutr Cancer. 2020 Jun 09;:1-10 Authors: Zhang L, Tang G, Wei Z Abstract Objective: Clinical trials have explored the role of curcumin in the prevention and treatment of oral mucositis (OM) in head and neck cancer patients. To provide evidence for curcumin management...
Wed Jun 10, 2020 14:25
Related ArticlesCOVID-19: An otolaryngological perspective. J Pak Med Assoc. 2020 May;70(Suppl 3)(5):S87-S94 Authors: Kaur N, Patro SK Abstract Otolaryngologists around the world are amongst the front-line fighters against the pandemic coronavirus disease (COVID-19). As knowledge about the disease epidemiology and clinical profile is rapidly evolving, we are still not sure about many different aspects of the disease transmission and presentation....
Wed Jun 10, 2020 14:25
Related ArticlesCochlear implantation and residual hearing preservation long-term follow-up of the first consecutively operated patients using the round window approach in Uppsala, Sweden. Cochlear Implants Int. 2020 Jun 09;:1-14 Authors: Schart-Morén N, Erixon E, Li H, Rask-Andersen H Abstract Objective: We conducted a long-term follow-up study to investigate the time course of residual hearing in our first 21 consecutively operated cochlear implant...
Wed Jun 10, 2020 14:25
Related ArticlesStandardization of patient modeling in hyperthermia simulation studies: introducing the Erasmus Virtual Patient Repository. Int J Hyperthermia. 2020;37(1):608-616 Authors: Bellizzi GG, Sumser K, VilasBoas-Ribeiro I, Curto S, Drizdal T, van Rhoon GC, Franckena M, Paulides MM Abstract Purpose: Thermal dose-effect relations have demonstrated that clinical effectiveness of hyperthermia would benefit from more controlled heating of the...
Wed Jun 10, 2020 14:25
Related ArticlesExamination of a dose evaluation method for floor-mounted kV X-ray image-guided radiation therapy systems. Radiol Phys Technol. 2020 Jun 08;: Authors: Hamada K, Fujibuchi T, Yoshida N, Ohura H Abstract Floor-mounted kV X-ray image-guided radiation therapy systems (such as ExacTrac) are used to treat tumors in movable body regions such as the head and neck. ExacTrac requires exposure dose control based on image acquisition. However,...
Wed Jun 10, 2020 13:26
Related ArticlesCompensatory motion scaling for time-delayed robotic surgery. Surg Endosc. 2020 Jun 08;: Authors: Orosco RK, Lurie B, Matsusaki T, Funk EK, Divi V, Holsinger FC, Hong S, Richter F, Das N, Yip M Abstract BACKGROUND: Round trip signal latency, or time delay, is an unavoidable constraint that currently stands as a major barrier to safe and efficient remote telesurgery. While there have been significant technological advancements aimed...
Wed Jun 10, 2020 13:26
Related ArticlesRelationship between the microvascular patterns observed by magnifying endoscopy with narrow-band imaging and the depth of invasion in superficial pharyngeal squamous cell carcinoma. Esophagus. 2020 Jun 08;: Authors: Sunakawa H, Hori K, Kadota T, Shinmura K, Yoda Y, Ikematsu H, Tomioka T, Akimoto T, Hayashi R, Fujii S, Yano T Abstract BACKGROUND: Prediction of the invasive depth is the objective of endoscopic observation for digestive...
Wed Jun 10, 2020 13:26
Related ArticlesLong-term outcomes and safety after reirradiation in locally recurrent nasopharyngeal carcinoma in a non-endemic area. Strahlenther Onkol. 2020 Jun 08;: Authors: Boustani J, Ruffier A, Moya-Plana A, Tao Y, Nguyen F, Even C, Berthold C, Casiraghi O, Temam S, Blanchard P Abstract PURPOSE: To determine outcomes and toxicities after reirradiation for locally recurrent nasopharyngeal carcinoma (rNPC) and to apply a prognostic index in...
Wed Jun 10, 2020 13:26
Related ArticlesImprovement of a delayed swallowing reflex following treatment for advanced head and neck cancer. Cancers Head Neck. 2020;5:8 Authors: Ohkoshi A, Kato K, Ogawa T, Nakanome A, Ishii R, Katori Y Abstract Background: The latency of the swallowing reflex is an important factor causing dysphagia in head and neck cancer patients. Although there are many reports comparing voluntary swallowing function before and after treatment, few studies...
Wed Jun 10, 2020 13:26
Related ArticlesChoroidal nevus and polypoidal vasculopathy: case series. Int J Retina Vitreous. 2020;6:19 Authors: Viana KÍS, Dalgalarrondo PF, Correa Z, Jorge R Abstract Background: To report an association between choroidal nevus and polypoidal choroidal vasculopathy (PCV) in three patients. Case presentation: We have encountered 3 isolated patients in our center presenting with subretinal exudation and a choroidal nevus that were thoroughly...
Wed Jun 10, 2020 13:26
Related ArticlesIbuprofen gargle for chemo- or Chemoradiotherapy-induced Oral Mucositis: a feasibility study. J Pharm Health Care Sci. 2020;6:12 Authors: Ioroi T, Kiyota N, Imamura Y, Tanda M, Aoki S, Okuno M, Yamamoto K, Sasaki R, Nibu KI, Minami H, Hirai M, Yano I Abstract Background: Oral mucositis frequently occurs in cancer patients treated with chemotherapy and chemoradiotherapy (CRT). This study examined the safety and efficacy of ibuprofen...
Wed Jun 10, 2020 13:26
Related ArticlesTonsillar granuloma associated with hypogammaglobulinemia. Allergy Asthma Clin Immunol. 2020;16:43 Authors: Laajala A, Kuismin O, Tastula M, Tiitto L, Kauppila S, Salo A, Åström P, Nissinen A, Glumoff V, Seppänen MRJ, Hautala T Abstract Background: Rare tonsillar granulomas may be caused for example by infections, malignancies or sarcoidosis. Granulomas also occur in inborn errors of immunity (IEI) such as common variable immunodeficiency...
Wed Jun 10, 2020 13:26
Related ArticlesEpidermal growth factor upregulates expression of MUC5AC via TMEM16A, in chronic rhinosinusitis with nasal polyps. Allergy Asthma Clin Immunol. 2020;16:40 Authors: Jiao J, Zhang T, Zhang Y, Li J, Wang M, Wang M, Li Y, Wang X, Zhang L Abstract Background: Mucus hypersecretion and goblet cell upregulation are common features of chronic rhinosinusitis with nasal polyps (CRSwNP). Although epidermal growth factor (EGF) has been reported...
Wed Jun 10, 2020 13:26
Related ArticlesLncRNA H19 promotes triple-negative breast cancer cells invasion and metastasis through the p53/TNFAIP8 pathway. Cancer Cell Int. 2020;20:200 Authors: Li Y, Ma HY, Hu XW, Qu YY, Wen X, Zhang Y, Xu QY Abstract Background: Long non-coding RNA H19 (lncRNA H19) has been implicated in tumorigenesis and metastasis of breast cancer through regulating epithelial to mesenchymal transition (EMT); however, the underlying mechanisms remain elusive....
Wed Jun 10, 2020 13:26
Related ArticlesImmunohistochemical evaluation of mismatch repair proteins and p53 expression in extrauterine carcinosarcoma/sarcomatoid carcinoma. Contemp Oncol (Pozn). 2020;24(1):1-4 Authors: Kunc M, Gabrych A, Rękawiecki B, Gorczyński A, Haybaeck J, Biernat W, Czapiewski P Abstract Introduction: Carcinosarcoma (CS) is a tumor with components: epithelial (carcinomatous) and mesenchymal (sarcomatous), developing in the mechanism of epithelial-mesenchymal...
Wed Jun 10, 2020 13:26
Related ArticlesAuthor Correction: TGF-β1-induced HSP47 regulates extracellular matrix accumulation via Smad2/3 signaling pathways in nasal fibroblasts. Sci Rep. 2020 Jun 09;10(1):9585 Authors: Kim HJ, Park JH, Shin JM, Yang HW, Lee HM, Park IH Abstract An amendment to this paper has been published and can be accessed via a link at the top of the paper.PMID: 32514115 [PubMed - in process]
Wed Jun 10, 2020 13:26
Related ArticlesFCRL4 Is an Fc Receptor for Systemic IgA, but Not Mucosal Secretory IgA. J Immunol. 2020 Jun 08;: Authors: Liu Y, Goroshko S, Leung LYT, Dong S, Khan S, Campisi P, Propst EJ, Wolter NE, Grunebaum E, Ehrhardt GRA Abstract Fc receptor-like (FCRL) 4 is an immunoregulatory receptor expressed on a subpopulation of human memory B cells of mucosa-associated lymphoid tissue. Fc receptor function of FCRL4 was demonstrated by binding of IgA...
Wed Jun 10, 2020 13:26
Related ArticlesAn intriguing 'cyst' of the ear. J Clin Pathol. 2020 Jun 08;: Authors: Tan GZL, Petersson F, Xu X, Thamboo TP PMID: 32513844 [PubMed - as supplied by publisher]
Wed Jun 10, 2020 13:26
Related ArticlesSimple technique to preserve the external branch of the superior laryngeal nerve during thyroidectomy: Clinical practicability of an attachable nerve stimulator. Asian J Surg. 2020 Jun 05;: Authors: Sung ES, Shin SC, Kwon HK, Lee YW, Lee JW, Jang HB, Ro JH, Lee JC, Lee BJ Abstract OBJECTIVE: This study aimed to demonstrate the usefulness of an attachable magnetic nerve stimulator for preservation of the external branch of the superior...
Wed Jun 10, 2020 13:26
Related ArticlesA Nasoendoscopic Study of "Head Resonance" and "Imposto" in Classical Singing. J Voice. 2020 Jun 06;: Authors: Aura M, Geneid A, Bjørkøy K, Rantanen M, Laukkanen AM Abstract BACKGROUND: Classical singing pedagogy uses many concepts which lack precise definition and whose acoustic and physiologic correlates are unclear. This study focuses on the concepts "head resonance" and "imposto." In singing guidebooks, head resonance has been...
Wed Jun 10, 2020 13:26
Related ArticlesLooking a Gift Horse in the Mouth: Observations on NHS England's Interim Guidance on Pembrolizumab in Head and Neck Squamous Cell Cancer. Clin Oncol (R Coll Radiol). 2020 Jun 05;: Authors: Harrington KJ, Bhide SA, Forster MD, Good JS, Gunn L, Kong A, Melcher AA, Metcalf R, Nenclares P, Newbold KL, Nutting CM, Prestwich R, Sacco JJ, Soliman H, Wong KH PMID: 32513517 [PubMed - as supplied by publisher]
Wed Jun 10, 2020 13:26
Related ArticlesConsensus document of the Spanish Society of Intensive and Critical Care Medicine and Coronary Units (SEMICYUC), the Spanish Society of Otorhinolaryngology and Head and Neck Surgery (SEORL-CCC) and the Spanish Society of Anesthesiology and Resuscitation (SEDAR) on tracheotomy in patients with COVID-19 infection. Acta Otorrinolaringol Esp. 2020 May 11;: Authors: Bernal-Sprekelsen M, Avilés-Jurado FX, Álvarez Escudero J, Aldecoa Álvarez-Santuyano C, de...
Wed Jun 10, 2020 13:26
Related ArticlesOrgan preservation after treatment with induction chemotherapy in patients with locally advanced carcinomas (T3-T4) of oral cavity and oropharynx. Acta Otorrinolaringol Esp. 2020 Jun 05;: Authors: León X, García J, López M, Farré N, Majercakova K, Gallego Ó, López-Pousa A, Quer M Abstract INTRODUCTION AND OBJECTIVES: With the goal of achieving functional preservation, one of the treatment strategies for patients with locally advanced...
Wed Jun 10, 2020 13:26
Related ArticlesFollow up imaging of oral, oropharyngeal and hypopharyngeal cancer patients: Comparison of PET-CT and MRI post treatment. J Craniomaxillofac Surg. 2020 Jun 04;: Authors: Breik O, Kumar A, Birchall J, Mortimore S, Laugharne D, Jones K Abstract There is currently no consensus as to the ideal timing, frequency and modality of imaging for follow up of head and neck cancer patients. The aim of this study was to analyze the diagnostic accuracy...
Wed Jun 10, 2020 13:26
Related ArticlesAerosol-generating procedures in head and neck surgery - can we improve practice after COVID-19? Br J Oral Maxillofac Surg. 2020 May 23;: Authors: Kerawala C, Riva F Abstract The COVID-19 pandemic has had a dramatic impact on international medicine practice. The propensity for head and neck surgery to generate aerosols needs special consideration over and above simply adopting personal protective equipment. This study sought to interrogate...
Wed Jun 10, 2020 13:26
Related ArticlesCutaneous metastases: A great imitator. Clin Dermatol. 2020 Mar - Apr;38(2):216-222 Authors: Jaros J, Hunt S, Mose E, Lai O, Tsoukas M Abstract Neoplastic cells originating from a primary cancer can uncommonly spread to the skin, where they suggest a poor prognosis for the patient. In women, melanoma, breast, ovarian, oral cavity, and lung are the most common primary sources; in men, melanoma, lung, colon, and squamous cell carcinoma...
Wed Jun 10, 2020 13:26
Related ArticlesEstimated Effect of COVID-19 Lockdown on Skin Tumor Size and Survival: An Exponential Growth Model. Actas Dermosifiliogr. 2020 May 11;: Authors: Tejera-Vaquerizo A, Cañueto J, Toll A, Santos-Juanes J, Jaka A, Ferrandiz-Pulido C, Sanmartín O, Ribero S, Moreno-Ramírez D, Almazán F, Fuente MJ, Podlipnik S, Nagore E Abstract BACKGROUND AND OBJECTIVES: Spain is in a situation of indefinite lockdown due to the ongoing coronavirus disease...
Wed Jun 10, 2020 13:26
Related ArticlesNorth American survey and systematic review on caudal Septoplasty. J Otolaryngol Head Neck Surg. 2020 Jun 08;49(1):38 Authors: Voizard B, Theriault M, Lazizi S, Moubayed SP Abstract BACKGROUND: Surgical correction of caudal septal deviation is a technically challenging step of functional rhinoplasty. Multiple surgical techniques have been described in the literature but comparing the efficacy of each in relieving obstruction presents...
Wed Jun 10, 2020 13:26
Related ArticlesOverlapping volumes in re-irradiation for head and neck cancer - an important factor for patient selection. Radiat Oncol. 2020 Jun 08;15(1):147 Authors: Embring A, Onjukka E, Mercke C, Lax I, Berglund A, Bornedal S, Wennberg B, Friesland S Abstract BACKGROUND: There is a lack of consensus concerning the definition of re-irradiation and re-irradiation volumes in head and neck cancer (HNC). The aim of the present study is to introduce...
Wed Jun 10, 2020 13:26
Related ArticlesThe effect of insulin-like growth factor 1 on the recovery of facial nerve function in a guinea pig model of facial palsy. J Physiol Sci. 2020 Jun 08;70(1):28 Authors: Sugiyama M, Ito T, Furukawa T, Hirayama A, Kakehata S Abstract The efficacy of insulin-like growth factor 1 (IGF-1) in the treatment of peripheral facial nerve palsy was investigated using an animal model. The facial nerve within the temporal bone was exposed and compressed...
Wed Jun 10, 2020 13:26
Related ArticlesTaste and Smell Impairment in COVID-19: An AAO-HNS Anosmia Reporting Tool-Based Comparative Study. Otolaryngol Head Neck Surg. 2020 Jun 09;:194599820931820 Authors: Sayin İ, Yaşar KK, Yazici ZM Abstract OBJECTIVE: To identify the taste and smell impairment in coronavirus disease 2019 (COVID-19)-positive subjects and compare the findings with COVID-19-negative subjects using the American Academy of Otolaryngology-Head and Neck Surgery...
Wed Jun 10, 2020 13:26
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