Related ArticlesRadiotherapy treatment for lung cancer: Current status and future directions. Respirology. 2020 Jun 09;: Authors: Vinod SK, Hau E Abstract Radiotherapy is an important modality used for the treatment of lung cancer. Seventy-seven percent of all patients with lung cancer have an evidence-based indication for radiotherapy, although it is often underutilized. Radiotherapy can be used as curative or palliative treatment across all stages...
Wed Jun 10, 2020 14:51
Related ArticlesDouble immune checkpoint blockade in advanced NSCLC. Crit Rev Oncol Hematol. 2020 May 19;152:102980 Authors: Mariniello A, Novello S, Scagliotti GV, Ramalingam SS Abstract Immunotherapy-based options for patients with advanced non-small cell lung cancer (NSCLC) are increasing at an unprecedented pace, carrying the promise to prolong survival of this deadly disease. To maximize responses and extend benefit to a larger portion of patients,...
Wed Jun 10, 2020 14:51
Related ArticlesStaging of bladder cancer with multiparametric MRI. Br J Radiol. 2020 Jun 09;:20200116 Authors: Juri H, Narumi Y, Panebianco V, Osuga K Abstract The distinction of non-muscle-invasive bladder cancer and muscle-invasive bladder cancer is important for the selection of the optimal treatment. Multiparametric MRI (mp-MRI) has been an useful modality for the T staging of bladder cancer, and a systematic evaluation of mp-MRI is needed. The...
Wed Jun 10, 2020 14:51
Related ArticlesImpact of the COVID-19 Global Pandemic on the Otolaryngology Fellowship Application Process. Otolaryngol Head Neck Surg. 2020 Jun 09;:194599820934370 Authors: Nesemeier BR, Lebo NL, Schmalbach CE, Barnes KJ, Vernon D, Ting JY, Shipchandler TZ Abstract On March 11, 2020, the World Health Organization declared coronavirus disease 2019 a global pandemic. In addition to massive social disruption, this pandemic affected the traditional fellowship...
Wed Jun 10, 2020 14:51
Related ArticlesDose prescription in SBRT for early-stage non-small cell lung cancer: are we all speaking the same language? Tumori. 2020 Jun 09;:300891620929425 Authors: Merlotti A, Bonomo P, Ragona R, Trovò M, Alongi F, Mazzola R, Vigna Taglianti R, Gianello L, Reali A, Bergesio F, Lucio F, Boriano A, De Maggi A, Russi E Abstract INTRODUCTION: Stereotactic body radiation therapy is increasingly used in the treatment of early-stage lung cancers. Guidelines...
Wed Jun 10, 2020 14:51
Related ArticlesIncidence of second primary malignancies in metastatic castration-resistant prostate cancer: results from observational studies in three countries. Future Oncol. 2020 Jun 09;: Authors: Vassilev ZP, Gabarró MS, Kaye JA, Saltus CW, Riedel O, Scholle O, Mehtälä J, Korhonen P, Garbe E, Zong J Abstract Aim: This reports some of the first incidence rate (IR) estimates of second primary malignancies (SPMs) in men with metastatic castration-resistant...
Wed Jun 10, 2020 14:51
Related ArticlesCardiac Biomarkers in Patients with Cancer: Considerations, Clinical Implications, and Future Avenues. Curr Oncol Rep. 2020 Jun 09;22(7):67 Authors: Bracun V, Aboumsallem JP, van der Meer P, de Boer RA Abstract PURPOSE OF THE REVIEW: As the number of cancer survivors increases due to early screening and modern (antineoplastic) treatments, cancer treatment associated cardiotoxicity (CTAC) is becoming an increasing health burden that affects...
Wed Jun 10, 2020 13:25
Related ArticlesProteasome Inhibitor-Related Cardiotoxicity: Mechanisms, Diagnosis, and Management. Curr Oncol Rep. 2020 Jun 08;22(7):66 Authors: Wu P, Oren O, Gertz MA, Yang EH Abstract PURPOSE OF REVIEW: Multiple myeloma is the second most common hematologic malignancy in the USA, with over 32,000 new cases and nearly 13,000 deaths expected in 2019. The past few decades in myeloma research have yielded significant advances, leading to the expansion...
Wed Jun 10, 2020 13:25
Related ArticlesAntifungal prophylaxis and novel drugs in acute myeloid leukemia: the midostaurin and posaconazole dilemma. Ann Hematol. 2020 Jun 08;: Authors: Stemler J, Koehler P, Maurer C, Müller C, Cornely OA Abstract With the advent of new targeted drugs in hematology and oncology patient prognosis is improved. Combination with antifungal prophylaxis challenges clinicians due to pharmacological profiles prone to drug-drug interactions (DDI). Midostaurin...
Wed Jun 10, 2020 13:25
Related Articles90Y-Radioembolization After Failed Portal Vein Embolization for Colorectal Liver Metastases: A Case Report. Cardiovasc Intervent Radiol. 2020 Jun 08;: Authors: Kurilova I, Pompa V, Guerrero R, Tapias MA, Calatayud MD, Fondevila C, González JA, Duch J, Gomez FM Abstract The main limiting factor for liver resection is insufficient future liver remnant (FLR). Portal vein embolization (PVE) is a standard of care treatment to induce FLR hypertrophy,...
Wed Jun 10, 2020 13:25
Related ArticlesEvaluation of liver tumour response by imaging. JHEP Rep. 2020 Jun;2(3):100100 Authors: Gregory J, Dioguardi Burgio M, Corrias G, Vilgrain V, Ronot M Abstract The goal of assessing tumour response on imaging is to identify patients who are likely to benefit - or not - from anticancer treatment, especially in relation to survival. The World Health Organization was the first to develop assessment criteria. This early score, which assessed...
Wed Jun 10, 2020 13:25
Related ArticlesReceptor tyrosine kinase targeting in glioblastoma: performance, limitations and future approaches. Contemp Oncol (Pozn). 2020;24(1):55-66 Authors: Alexandru O, Horescu C, Sevastre AS, Cioc CE, Baloi C, Oprita A, Dricu A Abstract From all central nervous system tumors, gliomas are the most common. Nowadays, researchers are looking for more efficient treatments for these tumors, as well as ways for early diagnosis. Receptor tyrosine kinases...
Wed Jun 10, 2020 13:25
Related ArticlesMulticenter Phase 1 Trial of a DNA Vaccine Encoding the Androgen Receptor Ligand Binding Domain (pTVG-AR, MVI-118) in Patients with Metastatic Prostate Cancer. Clin Cancer Res. 2020 Jun 08;: Authors: Kyriakopoulos CE, Eickhoff J, Ferrari AC, Schweizer MT, Wargowski E, Olson BM, McNeel DG Abstract PURPOSE: Preclinical studies demonstrated that a DNA vaccine (pTVG-AR, MVI-118) encoding the androgen receptor ligand-binding domain (AR LBD)...
Wed Jun 10, 2020 13:25
Related ArticlesEfficacy and safety of frontline regimens for older transplant-ineligible patients with multiple myeloma: A systematic review and meta-analysis. J Geriatr Oncol. 2020 Jun 05;: Authors: Giri S, Aryal MR, Yu H, Grimshaw A, Pathak R, Huntington SP, Dhakal B Abstract INTRODUCTION: Several treatment options are available for the management of older adults with newly diagnosed patients with Multiple Myeloma (MM) who are ineligible for hematopoietic...
Wed Jun 10, 2020 13:25
Related ArticlesNovel radiation therapy approaches for breast cancer treatment. Semin Oncol. 2020 May 29;: Authors: Shah C, Bauer-Nilsen K, McNulty RH, Vicini F Abstract The role of radiation therapy in the management of breast cancer continues to evolve. For patients with early stage breast cancer, hypofractionated whole breast irradiation following breast conserving surgery now represents the standard of care based on randomized data with long-term...
Wed Jun 10, 2020 13:25
Related ArticlesAnalysis of pulsed cisplatin signalling dynamics identifies effectors of resistance in lung adenocarcinoma. Elife. 2020 Jun 09;9: Authors: Hastings JF, Gonzalez Rajal A, Latham SL, Han JZ, McCloy RA, O'Donnell YE, Phimmachanh M, Murphy AD, Nagrial A, Daneshvar D, Chin V, Watkins DN, Burgess A, Croucher DR Abstract The identification of clinically viable strategies for overcoming resistance to platinum chemotherapy in lung adenocarcinoma...
Wed Jun 10, 2020 13:25
Related ArticlesOverlapping volumes in re-irradiation for head and neck cancer - an important factor for patient selection. Radiat Oncol. 2020 Jun 08;15(1):147 Authors: Embring A, Onjukka E, Mercke C, Lax I, Berglund A, Bornedal S, Wennberg B, Friesland S Abstract BACKGROUND: There is a lack of consensus concerning the definition of re-irradiation and re-irradiation volumes in head and neck cancer (HNC). The aim of the present study is to introduce a...
Wed Jun 10, 2020 13:25
Related ArticlesThe Expression, Functions and Mechanisms of Circular RNAs in Gynecological Cancers. Cancers (Basel). 2020 Jun 04;12(6): Authors: Dong P, Xu D, Xiong Y, Yue J, Ihira K, Konno Y, Watari H Abstract Circular RNAs (circRNAs) are covalently closed, endogenous non-coding RNAs and certain circRNAs are linked to human tumors. Owing to their circular form, circRNAs are protected from degradation by exonucleases, and therefore, they are more stable...
Wed Jun 10, 2020 13:25
Related ArticlesPre-Operative Combination of Normal BMI with Elevated YKL-40 and Leptin but Lower Adiponectin Level Is Linked to a Higher Risk of Breast Cancer Relapse: A Report of Four-Year Follow-Up Study. J Clin Med. 2020 Jun 04;9(6): Authors: Bielawski K, Rhone P, Bulsa M, Ruszkowska-Ciastek B Abstract Adipokines are powerful agents involved in the development of obesity-dependent cancers. This prospective study aimed to investigate the association...
Wed Jun 10, 2020 13:25
Publication date: June 2020Source: Gene Expression Patterns, Volume 36Author(s):
Wed Jun 10, 2020 13:22
Publication date: June 2020Source: Gene Expression Patterns, Volume 36Author(s):
Wed Jun 10, 2020 13:22
Publication date: Available online 10 June 2020Source: Cancer/RadiothérapieAuthor(s): V. Karahissarlian, P. Sargos, E. Blais, A.-L. Cazeau, F. Fontes, F. Petitpierre, G. Rigou, C. De Vaugelade, A. Mariey, E. Hindié, L. Thomas
Wed Jun 10, 2020 13:20
Related ArticlesInvestigation of the combination of anti-PD-L1 mAb with HER2/neu-loaded dendritic cells and QS-21 saponin adjuvant: effect against HER2 positive breast cancer in mice. Immunopharmacol Immunotoxicol. 2020 Jun 09;:1-12 Authors: Özverel CS, Uyanikgil Y, Karaboz İ, Nalbantsoy A Abstract Background: Human epidermal growth factor receptor 2 (HER2) is overexpressed in a subset of cancers including 25% of breast cancers. Since combination therapy...
Wed Jun 10, 2020 19:14
Related ArticlesDioscin exhibits anti-inflammatory effects in IL-1β-stimulated human osteoarthritis chondrocytes by activating LXRα. Immunopharmacol Immunotoxicol. 2020 Jun 09;:1-6 Authors: Wang H, Zhu H, Yang X Abstract Objective: Osteoarthritis (OA) is the most common joint disease that characterized by the degradation of articular cartilage. In this study, we aimed to investigate the anti-inflammatory activity of dioscin on IL-1β-stimulated human...
Wed Jun 10, 2020 19:14
Aim/Objectives/Background: The goal of therapy with unsealed radiopharmaceutical sources is to provide either cure or significant prolongation of disease-specific survival, and effective reduction and/or prevention of adverse disease-related symptoms or untoward events while minimizing treatment-associated side effects and complications. Radium-223 dichloride (radium-223) is an alpha particle–emitting isotope used for targeted bone therapy. This practice parameter is intended to guide appropriately...
Wed May 27, 2020 03:00
Background: The incidence of liver cancer has more than tripled since 1980. Hepatectomy represents the major curative treatment for liver cancer. The risk factors associated with 90-day mortality after hepatectomy are not well understood and there are currently no good prediction models for this outcome. The objectives of the current study were to identify risk factors of 90-day mortality after hepatectomy in patients with hepatocellular carcinoma and to develop an integer-based risk score using...
Wed May 27, 2020 03:00
During the course of therapy, patients with small cell lung cancer have been noted to develop transformation to non–small cell lung cancer and conversely, patients with non–small cell lung cancer have had transformation to small cell lung cancer or other non–small cell histologies. Transformation may occur after prior tyrosine kinase inhibitors, chemotherapy, immunotherapy or radiation therapy. These changes reflect on the overlapping biology of these cell types and the clinical need for re-biopsy...
Wed May 27, 2020 03:00
Aim/Objectives/Background: Timely, accurate, and effective communications are critical to quality in contemporary medical practices. Radiation oncology incorporates the science and technology of complex integrated radiation treatment delivery and the art of managing individual patients. Through written physical and/or electronic reports and direct communication, radiation oncologists convey critical information regarding patient care, services provided, and quality of care. Applicable practice...
Wed May 27, 2020 03:00
No abstract available
Wed May 27, 2020 03:00
Publication date: Available online 10 June 2020Source: British Journal of Oral and Maxillofacial SurgeryAuthor(s): AGC Hay-David, JBT Herron, PA Brennan
Wed Jun 10, 2020 13:12
Publication date: Available online 10 June 2020Source: British Journal of Oral and Maxillofacial SurgeryAuthor(s): Q. You, X. jing, S. Fan, Y. Wang, Z. Yang
Wed Jun 10, 2020 13:12
Publication date: Available online 9 June 2020Source: British Journal of Oral and Maxillofacial SurgeryAuthor(s): N. Solano, B. Castro, L. Perez, S. Ramos, A. Peraza
Wed Jun 10, 2020 13:12
Related ArticlesClinical impact of sleep-disordered breathing on very short-term blood pressure variability determined by pulse transit time. J Hypertens. 2020 Jun 06;: Authors: Misaka T, Niimura Y, Yoshihisa A, Wada K, Kimishima Y, Yokokawa T, Abe S, Oikawa M, Kaneshiro T, Kobayashi A, Yamaki T, Kunii H, Takeishi Y Abstract BACKGROUND: Sleep-disordered breathing (SDB) and blood pressure variability (BPV) are strongly associated with cardiovascular diseases....
Wed Jun 10, 2020 15:37
Related ArticlesPerformance of peripheral arterial tonometry based testing for the diagnosis of obstructive sleep apnea in a large sleep clinic cohort. J Clin Sleep Med. 2020 Jun 09;: Authors: Ioachimescu OC, Allam JS, Samarghandi A, Anand N, Fields BG, Dholakia SA, Venkateshiah SB, Eisenstein R, Ciavatta MM, Collop NA Abstract STUDY OBJECTIVES: Peripheral arterial tonometry (PAT) based technology represents a validated portable monitoring modality for...
Wed Jun 10, 2020 15:37
Related ArticlesNight-to-night fluctuations in sleep apnea severity: diagnostic and treatment implications and the need to be less prescriptive in guidelines. J Clin Sleep Med. 2020 Jun 09;: Authors: Hunasikatti M PMID: 32515346 [PubMed - as supplied by publisher]
Wed Jun 10, 2020 15:37
Related ArticlesA case of Madelung's disease presenting with obstructive sleep apnea. J Clin Sleep Med. 2020 Jun 09;: Authors: Segsarnviriya C, Chirakalwasan N Abstract None: Madelung's disease is a rare condition characterized by diffuse, multiple, symmetric, non-encapsulated, fatty accumulation predominantly in neck and upper trunk which can predispose to obstructive sleep apnea (OSA). This case report involves a 51-year-old man affected by Madelung's...
Wed Jun 10, 2020 15:37
Related ArticlesInterpreting CPAP device respiratory indices in children. J Clin Sleep Med. 2020 Jun 09;: Authors: Mihai R, Ellis K, Davey MJ, Nixon GM Abstract STUDY OBJECTIVES: An increasing number of children with obstructive sleep apnea (OSA) require treatment with continuous positive airway pressure (CPAP). This study aimed to determine whether automatic respiratory indices from a CPAP device accurately predict manually determined respiratory indices...
Wed Jun 10, 2020 15:37
Related ArticlesObjective rest-activity cycle analysis by actigraphy identifies isolated REM sleep behavior disorder. Eur J Neurol. 2020 Jun 09;: Authors: Filardi M, Stefani A, Holzknecht E, Pizza F, Plazzi G, Högl B Abstract INTRODUCTION: Isolated REM sleep behavior disorder (iRBD) is characterized by abnormal behaviours during REM sleep. Several studies showed that iRBD is a prodromal stage of synucleinopathies. Therefore identifying iRBD in the general...
Wed Jun 10, 2020 13:12
Related ArticlesImmunoreactivity to metal and silica associates with sarcoidosis in Dutch patients. Respir Res. 2020 Jun 08;21(1):141 Authors: Beijer E, Meek B, Bossuyt X, Peters S, Vermeulen RCH, Kromhout H, Veltkamp M Abstract BACKGROUND: Involvement of metals or silica in the pathogenesis of sarcoidosis has been suggested by several case reports and specific epidemiological studies. However, the combination of occupational exposure and an immunological...
Wed Jun 10, 2020 13:12
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