Antibiotics, Vol. 9, Pages 122: Molecular Epidemiology of Staphylococcus aureus Lineages in Wild Animals in Europe: A Review Antibiotics doi: 10.3390/antibiotics9030122 Authors: Vanessa Silva José L. Capelo Gilberto Igrejas Patrícia Poeta Staphylococcus aureus is an opportunist pathogen that is responsible for numerous types of infections. S. aureus is known for its ability to easily acquire antibiotic resistance determinants. Methicillin-resistant S. aureus (MRSA) is a leading...
Antibiotics, Vol. 9, Pages 123: A Novel, Integron-Regulated, Class C β-Lactamase Antibiotics doi: 10.3390/antibiotics9030123 Authors: Maria-Elisabeth Böhm Mohammad Razavi Carl-Fredrik Flach D. G. Joakim Larsson AmpC-type β-lactamases severely impair treatment of many bacterial infections, due to their broad spectrum (they hydrolyze virtually all β-lactams, except fourth-generation cephalosporins and carbapenems) and the increasing incidence of plasmid-mediated...
Antibiotics, Vol. 9, Pages 120: Antibiotic Resistance Genes in Antibiotic-Free Chicken Farms Antibiotics doi: 10.3390/antibiotics9030120 Authors: Yuhong Liu Michael Dyall-Smith Marc Marenda Hang-Wei Hu Glenn Browning Helen Billman-Jacobe Rising concern about the use of antibiotics in food production has resulted in many studies on the occurrence of antibiotic resistance genes (ARGs) in animal-associated bacterial communities. There are few baseline data on the abundance...
Antibiotics, Vol. 9, Pages 121: Antibiotic Resistance and Therapy Outcome in H. pylori Eradication Failure Patients Antibiotics doi: 10.3390/antibiotics9030121 Authors: Saracino Pavoni Zullo Fiorini Saccomanno Lazzarotto Cavallo Antonelli Vaira Helicobacter pylori (H. pylori) eradication fails in a definite amount of patients despite one or more therapeutic attempts. Curing these patients is progressively more difficult, due to development of antibiotic...
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Antioxidants, Vol. 9, Pages 239: Impact of Fermentation on the Recovery of Antioxidant Bioactive Compounds from Sea Bass Byproducts Antioxidants doi: 10.3390/antiox9030239 Authors: Francisco J. Martí-Quijal Adrián Tornos Andrea Príncep Carlos Luz Giuseppe Meca Paola Tedeschi María-José Ruiz Francisco J. Barba The aim of the present research was to obtain antioxidant compounds through the fermentation of fish byproducts by bacteria isolated from sea bass viscera....
Antioxidants, Vol. 9, Pages 238: Characterization of Arils Juice and Peel Decoction of Fifteen Varieties of Punica granatum L.: A Focus on Anthocyanins, Ellagitannins and Polysaccharides Antioxidants doi: 10.3390/antiox9030238 Authors: Balli Cecchi Khatib Bellumori Cairone Carradori Zengin Cesa Innocenti Mulinacci Pomegranate is receiving renewed commercial and scientific interest, therefore a deeper knowledge of the chemical composition of the fruits...
Antioxidants, Vol. 9, Pages 237: Improvement of Testicular Steroidogenesis Using Flavonoids and Isoflavonoids for Prevention of Late-Onset Male Hypogonadism Antioxidants doi: 10.3390/antiox9030237 Authors: Martin Touaibia Androgen production, being important for male fertility, is mainly accomplished by the Leydig cells from the interstitial compartment of the testis. Testosterone plays a critical role in testis development, normal masculinization, and the maintenance of spermatogenesis....
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Atmosphere, Vol. 11, Pages 286: Quantitative Fluxes of the Greenhouse Gases CH4 and CO2 from the Surfaces of Selected Polish Reservoirs Atmosphere doi: 10.3390/atmos11030286 Authors: Renata Gruca-Rokosz Research carried out in the years 2009–2011 and 2018–2019 sought to determine the magnitudes of fluxes of methane (CH4) and carbon dioxide (CO2) from the surfaces of three eutrophic reservoirs in SE Poland. The “static chamber” method was deployed...
Atmosphere, Vol. 11, Pages 285: Analysis of Air Pollution in Urban Areas with Airviro Dispersion Model—A Case Study in the City of Sheffield, United Kingdom Atmosphere doi: 10.3390/atmos11030285 Authors: Said Munir Martin Mayfield Daniel Coca Lyudmila S Mihaylova Ogo Osammor Two air pollutants, oxides of nitrogen (NOx) and particulate matter (PM10), are monitored and modelled employing Airviro air quality dispersion modelling system in Sheffield, United Kingdom. The aim is...
Atmosphere, Vol. 11, Pages 284: The Comprehensive Study of Low Thermospheric Sodium Layers during the 24th Solar Cycle Atmosphere doi: 10.3390/atmos11030284 Authors: Yuchang Xun Guotao Yang Jihong Wang Lifang Du Zelong Wang Jing Jiao Xuewu Cheng Faquan Li Xu Zou The low thermospheric sodium layer (LTSL) is the separate sodium atom layer above 105 km. Based on 11,607 h of lidar observations from Yanqing (40.5° N, 116.0° E) from 2010 to 2016, we...
Atmosphere, Vol. 11, Pages 282: Pro-Pluvia Rogation Ceremonies in Extremadura (Spain): Are They a Good Proxy of Winter NAO? Atmosphere doi: 10.3390/atmos11030282 Authors: Nieves Bravo-Paredes María Cruz Gallego Fernando Domínguez-Castro José Agustín García José Manuel Vaquero Rogation ceremonies are religious requests to God. Pro-pluvia rogations were celebrated during dry conditions to ask God for rain. In this work, we have recovered 37 pro-pluvia rogations from 14 documentary...
Atmosphere, Vol. 11, Pages 283: Effects of UV-A Light Treatment on Ammonia, Hydrogen Sulfide, Greenhouse Gases, and Ozone in Simulated Poultry Barn Conditions Atmosphere doi: 10.3390/atmos11030283 Authors: Myeongseong Lee Jisoo Wi Jacek A. Koziel Heekwon Ahn Peiyang Li Baitong Chen Zhanibek Meiirkhanuly Chumki Banik William Jenks Gaseous emissions, a side effect of livestock and poultry production, need to be mitigated to improve sustainability. Emissions of ammonia...
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Behavioral Sciences, Vol. 10, Pages 68: The Relationship of Thinking Style and Motivation Features of Sales and Advertising Managers Behavioral Sciences doi: 10.3390/bs10030068 Authors: Alla Belousova Yulia Mochalova The thinking of a manager is conditioned by their motivational features which determine their personal professional success and the effectiveness of the organization’s activities. In this study, we assumed that two groups of sales and advertising managers had...
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Bioengineering, Vol. 7, Pages 28: Low Temperature Dissolution of Yeast Chitin-Glucan Complex and Characterization of the Regenerated Polymer Bioengineering doi: 10.3390/bioengineering7010028 Authors: Diana Araújo Vítor D. Alves Ana C. Marques Elvira Fortunato Maria A. M. Reis Filomena Freitas Chitin-glucan complex (CGC) is a copolymer composed of chitin and glucan moieties extracted from the cell-walls of several yeasts and fungi. Despite its proven valuable properties,...
Bioengineering, Vol. 7, Pages 27: Biomechanical Behavior of a Variable Angle Locked Tibiotalocalcaneal Construct Bioengineering doi: 10.3390/bioengineering7010027 Authors: Farah Hamandi Gerard Simon Richard Laughlin Tarun Goswami This paper examines the mechanics of the tibiotalocalcaneal construct made with a PHILOS plating system. A failed device consisting of the LCP plate and cortical, locking, and cannulated screws was used to perform the analysis. Visual, microstructure,...
Bioengineering, Vol. 7, Pages 26: Biogenic Ceria Nanoparticles (CeO2 NPs) for Effective Photocatalytic and Cytotoxic Activity Bioengineering doi: 10.3390/bioengineering7010026 Authors: Siripireddy Balaji Badal Kumar Mandal L. Vinod Kumar Reddy Dwaipayan Sen Ceria nanoparticles (CeO2 NPs) are generally considered in various functional applications, such as catalysts in fuel cells, sensors, and antioxidant and oxidase-like enzymes in the biological environment. The CeO2 NPs were...
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Biology, Vol. 9, Pages 54: Ex Vivo Rat Transected Spinal Cord Slices as a Model to Assess Lentiviral Vector Delivery of Neurotrophin-3 and Short Hairpin RNA against NG2 Biology doi: 10.3390/biology9030054 Authors: Azim Patar Peter Dockery Siobhan McMahon Linda Howard The failure of the spinal cord to regenerate can be attributed both to a lack of trophic support for regenerating axons and to upregulation of inhibitory factors such as chondroitin sulphate proteoglycans including...
Biology, Vol. 9, Pages 53: Molecular Imaging of Galectin-1 Expression as a Biomarker of Papillary Thyroid Cancer by Using Peptide-Functionalized Imaging Probes Biology doi: 10.3390/biology9030053 Authors: Deborah Fanfone Dimitri Stanicki Denis Nonclercq Marc Port Luce Vander Elst Sophie Laurent Robert N. Muller Sven Saussez Carmen Burtea Thyroid cancers are the most frequent endocrine cancers and their incidence is increasing worldwide. Thyroid nodules occur in...
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Biomedicines, Vol. 8, Pages 59: Aptamers Increase Biocompatibility and Reduce the Toxicity of Magnetic Nanoparticles Used in Biomedicine Biomedicines doi: 10.3390/biomedicines8030059 Authors: Galina S. Zamay Tatiana N. Zamay Kirill A. Lukyanenko Anna S. Kichkailo Aptamer-based approaches are very promising tools in nanomedicine. These small single-stranded DNA or RNA molecules are often used for the effective delivery and increasing biocompatibility of various therapeutic agents....
Biomedicines, Vol. 8, Pages 58: Unraveling the Role of Inwardly Rectifying Potassium Channels in the Hippocampus of an Aβ(1–42)-Infused Rat Model of Alzheimer’s Disease Biomedicines doi: 10.3390/biomedicines8030058 Authors: Akyuz Villa Beker Elibol Alzheimer’s disease (AD) is a progressive neurodegenerative disorder with a complex etiology and characterized by cognitive deficits and memory loss. The pathogenesis of AD is not yet completely elucidated, and no curative...
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Biomolecules, Vol. 10, Pages 456: Lactoferrin’s Anti-Cancer Properties: Safety, Selectivity, and Wide Range of Action Biomolecules doi: 10.3390/biom10030456 Authors: Antimo Cutone Luigi Rosa Giusi Ianiro Maria Stefania Lepanto Maria Carmela Bonaccorsi di Patti Piera Valenti Giovanni Musci Despite recent advances in cancer therapy, current treatments, including radiotherapy, chemotherapy, and immunotherapy, although beneficial, present attendant side effects and long-term...
Biomolecules, Vol. 10, Pages 455: Biological Evaluation and Docking Studies of New Carbamate, Thiocarbamate, and Hydrazide Analogues of Acyl Homoserine Lactones as Vibrio fischeri-Quorum Sensing Modulators Biomolecules doi: 10.3390/biom10030455 Authors: Qiang Zhang Yves Queneau Laurent Soulère A series of carbamate, thiocarbamate, and hydrazide analogues of acylhomoserine lactones (AHLs) were synthesized and their ability to modulate Vibrio fischeri-quorum sensing was evaluated....
Biomolecules, Vol. 10, Pages 454: Machine Learning to Identify Flexibility Signatures of Class A GPCR Inhibition Biomolecules doi: 10.3390/biom10030454 Authors: Joseph Bemister-Buffington Alex J. Wolf Sebastian Raschka Leslie A. Kuhn We show that machine learning can pinpoint features distinguishing inactive from active states in proteins, in particular identifying key ligand binding site flexibility transitions in GPCRs that are triggered by biologically active ligands. Our...
Biomolecules, Vol. 10, Pages 451: Polyphenolic Compounds from Lespedeza Bicolor Root Bark Inhibit Progression of Human Prostate Cancer Cells via Induction of Apoptosis and Cell Cycle Arrest Biomolecules doi: 10.3390/biom10030451 Authors: Sergey A. Dyshlovoy Darya Tarbeeva Sergey Fedoreyev Tobias Busenbender Moritz Kaune Marina Veselova Anatoliy Kalinovskiy Jessica Hauschild Valeria Grigorchuk Natalya Kim Carsten Bokemeyer Markus Graefen Petr Gorovoy Gunhild...
Biomolecules, Vol. 10, Pages 453: The TGFβ Family in Human Placental Development at the Fetal-Maternal Interface Biomolecules doi: 10.3390/biom10030453 Authors: Chuva de Sousa Lopes Alexdottir Valdimarsdottir Emerging data suggest that a trophoblast stem cell (TSC) population exists in the early human placenta. However, in vitro stem cell culture models are still in development and it remains under debate how well they reflect primary trophoblast (TB) cells. The absence of robust...
Biomolecules, Vol. 10, Pages 452: Green Synthesis of Gold Nanoparticles Capped with Procyanidins from Leucosidea sericea as Potential Antidiabetic and Antioxidant Agents Biomolecules doi: 10.3390/biom10030452 Authors: Umar M. Badeggi Enas Ismail Adewale O. Adeloye Subelia Botha Jelili A. Badmus Jeanine L. Marnewick Christopher N. Cupido Ahmed A. Hussein In this study, procyanidins fractions of dimers and trimers (F1–F2) from the Leucosidea sericea total...
Biomolecules, Vol. 10, Pages 450: Mitochondrial Dynamics Regulation in Skin Fibroblasts from Mitochondrial Disease Patients Biomolecules doi: 10.3390/biom10030450 Authors: Tokuyama Hirai Shiiba Ito Matsuno Takeda Saito Mii Matsushita Fukuda Inatome Yanagi Mitochondria are highly dynamic organelles that constantly fuse, divide, and move, and their function is regulated and maintained by their morphologic changes. Mitochondrial disease (MD)...
Biomolecules, Vol. 10, Pages 446: Methylation of the Suppressor Gene p16INK4a: Mechanism and Consequences Biomolecules doi: 10.3390/biom10030446 Authors: Alfonso Tramontano Francesca Ludovica Boffo Giusi Russo Mariarosaria De Rosa Ilaria Iodice Antonio Pezone Tumor suppressor genes in the CDKN2A/B locus (p15INK4b, p16INK4a, and p14ARF) function as biological barriers to transformation and are the most frequently silenced or deleted genes in human cancers. This gene silencing...
Biomolecules, Vol. 10, Pages 449: Genomic Landscape and Mutational Spectrum of ADAMTS Family Genes in Mendelian Disorders Based on Gene Evidence Review for Variant Interpretation Biomolecules doi: 10.3390/biom10030449 Authors: John Hoon Rim Yo Jun Choi Heon Yung Gee ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) are a family of multidomain extracellular protease enzymes with 19 members. A growing number of ADAMTS family gene variants have been identified...
Biomolecules, Vol. 10, Pages 448: Does Cysteine Rule (CysR) Complete the CendR Principle? Increase in Affinity of Peptide Ligands for NRP-1 Through the Presence of N-Terminal Cysteine Biomolecules doi: 10.3390/biom10030448 Authors: Anna K. Puszko Piotr Sosnowski Françoise Raynaud Olivier Hermine Gérard Hopfgartner Yves Lepelletier Aleksandra Misicka The structure-activity relationship of branched H-Lys(hArg)-Dab-Dhp-Arg-OH sequence analogues, modified with Cys-Asp or...
Biomolecules, Vol. 10, Pages 447: Role of 3-Mercaptopyruvate Sulfurtransferase in the Regulation of Proliferation, Migration, and Bioenergetics in Murine Colon Cancer Cells Biomolecules doi: 10.3390/biom10030447 Authors: Fiona Augsburger Elisa B. Randi Mathieu Jendly Kelly Ascencao Nahzli Dilek Csaba Szabo 3-mercaptopyruvate sulfurtransferase (3-MST) has emerged as one of the significant sources of biologically active sulfur species in various mammalian cells. The current...
Biomolecules, Vol. 10, Pages 444: Pro-Resolving Effect of Ginsenosides as an Anti-Inflammatory Mechanism of Panax ginseng Biomolecules doi: 10.3390/biom10030444 Authors: Im : Panax ginseng, also known as Korean ginseng, is a famous medicinal plant used for the treatment of many inflammatory diseases. Ginsenosides (ginseng saponins) are the main class of active constituents of ginseng. The anti-inflammatory effects of ginseng extracts were proven with purified ginsenosides, such as ginsenosides...
Biomolecules, Vol. 10, Pages 445: Synergisms, Discrepancies and Interactions between Hydrogen Sulfide and Carbon Monoxide in the Gastrointestinal and Digestive System Physiology, Pathophysiology and Pharmacology Biomolecules doi: 10.3390/biom10030445 Authors: Głowacka Brzozowski Magierowski Endogenous gas transmitters, hydrogen sulfide (H2S), carbon monoxide (CO) and nitric oxide (NO) are important signaling molecules known to exert multiple biological functions. In recent years,...
Biomolecules, Vol. 10, Pages 443: Succinamide Derivatives Ameliorate Neuroinflammation and Oxidative Stress in Scopolamine-Induced Neurodegeneration Biomolecules doi: 10.3390/biom10030443 Authors: Sumbal Iqbal Fawad Ali Shah Komal Naeem Humaira Nadeem Sadia Sarwar Zaman Ashraf Muhammad Imran Tariq Khan Tayyaba Anwar Shupeng Li Oxidative stress-mediated neuroinflammatory events are the hallmark of neurodegenerative diseases. The current study aimed to synthesize...
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Biosensors, Vol. 10, Pages 24: A Label-Free Immunosensor Based on Graphene Oxide/Fe3O4/Prussian Blue Nanocomposites for the Electrochemical Determination of HBsAg Biosensors doi: 10.3390/bios10030024 Authors: Shanshan Wei Haolin Xiao Liangli Cao Zhencheng Chen In this article, a highly sensitive label-free immunosensor based on a graphene oxide (GO)/Fe3O4/Prussian blue (PB) nanocomposite modified electrode was developed for the determination of human hepatitis B surface antigen...
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Brain Sciences, Vol. 10, Pages 170: Acquisition of Ownership Illusion with Self-Disownership in Neurological Patients Brain Sciences doi: 10.3390/brainsci10030170 Authors: Pazzaglia Giannini Federico The multisensory regions in frontoparietal cortices play a crucial role in the sense of body and self. Disrupting this sense may lead to a feeling of disembodiment, or more generally, a sense of disownership. Experimentally, this altered consciousness disappears during illusory...
Brain Sciences, Vol. 10, Pages 169: Early Life Stress and Pediatric Posttraumatic Stress Disorder Brain Sciences doi: 10.3390/brainsci10030169 Authors: Panagiota Pervanidou Gerasimos Makris George Chrousos Agorastos Agorastos Traumatic stress exposure during critical periods of development may have essential and long-lasting effects on the physical and mental health of individuals. Two thirds of youth are exposed to potentially traumatic experiences by the age of 17, and approximately...
Brain Sciences, Vol. 10, Pages 167: Exposure Therapy for Post-Traumatic Stress Disorder: Factors of Limited Success and Possible Alternative Treatment Brain Sciences doi: 10.3390/brainsci10030167 Authors: Markowitz Fanselow Recent research indicates that there is mixed success in using exposure therapies on patients with post-traumatic stress disorder (PTSD). Our study argues that there are two major reasons for this: The first is that there are nonassociative aspects of PTSD, such...
Brain Sciences, Vol. 10, Pages 166: Exploratory Analysis of iPSCS-Derived Neuronal Cells as Predictors of Diagnosis and Treatment of Alzheimer Disease Brain Sciences doi: 10.3390/brainsci10030166 Authors: Eugenio Cavalli Giuseppe Battaglia Maria Sofia Basile Valeria Bruno Maria Cristina Petralia Salvo Danilo Lombardo Manuela Pennisi Reni Kalfin Lyubka Tancheva Paolo Fagone Ferdinando Nicoletti Katia Mangano Alzheimer’s disease (AD) represents...
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