Publication date: Available online 13 March 2020Source: Journal of the American College of SurgeonsAuthor(s): Xuping Cheng, Weimin Zhang, Kailei Du
Fri Mar 13, 2020 13:06
Publication date: Available online 13 March 2020Source: Journal of the American College of SurgeonsAuthor(s): Mitchell H. Tsai, Franklin Dexter
Fri Mar 13, 2020 13:06
Publication date: Available online 13 March 2020Source: Journal of the American College of SurgeonsAuthor(s): Edmund K. Bartlett, Daniel G. Coit
Fri Mar 13, 2020 13:06
Publication date: Available online 13 March 2020Source: Journal of the American College of SurgeonsAuthor(s): Beau Aldridge, Leslie Robinson
Fri Mar 13, 2020 13:06
Abstract Oral squamous cell carcinoma is associated with many known risk factors including tobacco smoking, chronic alcoholism, poor oral hygiene, unhealthy dietary habits and microbial infection. Previous studies have highlighted Candida albicans host tissue infection as a risk factor in the initiation and progression of oral cancer. C. albicans invasion induces several cancerous hallmarks, such as activation of proto‐oncogenes, induction of DNA damage and overexpression of inflammatory signalling...
Sun Mar 15, 2020 21:36
Abstract Background Aberrant miRNAs expression regulates the occurrence and progression of a variety of cancers, including oral squamous cell carcinoma (OSCC). This study aims to illustrate the potential effects of miR‐454/nuclear receptor subfamily 3 group C member 2 (NR3C2) on the biological behaviors of OSCC cells. Methods GEO database was applied to detect and analyze the expression of miR‐545 and NR3C2 in OSCC tissues. Two OSCC cell lines including CAL27 and Tca‐83 were utilized...
Sun Mar 15, 2020 21:36
Abstract Revisiting the eponymous ‘Peter Principle’, in this article the author reflects upon a professional lifetime as a clinician, surgeon and researcher, and summarizes his efforts to improve contemporary understanding of oral cancer development, refine diagnostic procedure and facilitate efficacious, early treatment intervention to halt the process of carcinogenesis. The author reviews the principles underpinning effective translational research. Utilising his own work in oral epithelial...
Sun Mar 15, 2020 21:36
Abstract The Peter Principle’ was published over 50‐years ago by Laurence J Peter as an alterative view of corporate management in which members of a hierarchical organization climb ‘upwards’, eventually reaching their own individual level of incompetence.1 Following extensive discussions between two JOPM editors both sharing Peter as their first name (Peter Thomson, Associate Editor and me as Editor in Chief), we felt that it was time to consider an alternative, less cynical, ‘Peter Principle.’
Sun Mar 15, 2020 21:36
Abstract Oral cancer is easily detectable by physical (self) examination. However, many cases of oral cancer are detected late, which causes unnecessary morbidity and mortality. Screening of high‐risk populations seems beneficial, but these populations are commonly located in regions with limited access to healthcare. The advent of information technology and its modern derivative Artificial Intelligence (AI) promises to improve oral cancer screening but to date, few efforts have been made to apply...
Sun Mar 15, 2020 21:36
Abstract Electronic cigarettes (e‐cigarettes) are a popular method to help quit tobacco smoking. However, there is paucity of data in the literature on their safety and efficacy. Recently, the Indian government has called for a ban on all e‐cigarettes and taken steps to restrict access to vaping products from the market. This major decision was an attempt to safeguard the younger population from using e‐cigarette and their possible longer‐term addiction together with its promotions by domestic...
Sun Mar 15, 2020 21:36
Congenital anomalies are caused by a variety of risk factors, including individual and environmental ones. This study estimated the prevalence of oral clefts and examined their area‐level risk indicators using data from The National Congenital Anomaly Survey in South Korea. Disease mapping and ecological regression were used to assess the geographical variation and potential risk indicators for oral clefts, such as living in a rural area, material deprivation, and limited access to antenatal healthcare....
Sun Mar 15, 2020 21:21
Trust has a central role in healthcare encounters. This review explored concepts relevant to trust in dentist‐patient relationships. The findings were demonstrated by drawing visual system maps for better understanding of the inherent complexity. A pragmatic approach was employed to search for evidence. The approach was initiated with a systematised searching protocol and followed by an iterative process of drawing maps and complementing references. The analysis‐synthesis process found relevant key...
Sun Mar 15, 2020 21:21
DNA damage repair is a key factor in the maintenance of cell genome stability, plays an important role in the regulation of tumour evolution, and can affect the prognosis of cancer patients. This study aimed to detect the protein expression of the DNA damage repair protein P53 and its upstream and downstream regulators, CHK1, GADD45A, and MDM2, in oral squamous cell carcinoma (OSCC), in order to analyse the association between the expression of these proteins and overall survival, and to assess their...
Sun Mar 15, 2020 21:21
The aim of this study was to evaluate the hydrophilicity, surface free energy, and proliferation and viability of human osteoblast‐like MC3T3‐E1 cells on sandblasted and acid‐etched titanium surfaces after air‐abrasion with 45S5 bioactive glass, zinc‐containing bioactive glass, or inert glass. Sandblasted and acid‐etched titanium discs were subjected to air‐abrasion with 45S5 bioactive glass, experimental bioactive glass (Zn4), or inert glass. Water contact angles and surface free energy were evaluated....
Sun Mar 15, 2020 21:21
Abstract Hereditary hemorrhagic telangiectasia (HHT) is a rare autosomal dominant disease. The diagnostic criteria of HHT, or Curaçao criteria, include the following: recurrent epistaxis or nighttime nose bleeding, mucocutaneous telangiectases, visceral arteriovenous malformation, or an appropriate family history. The diagnosis is classified as definite if three criteria are present, possible if two criteria are present, and unlikely if only one is present. Nowadays, the confirmation of HHT diagnosis...
Sun Mar 15, 2020 21:12
Abstract Physical examinations are recommended as part of a comprehensive evaluation for individuals with neurodevelopmental disorders (NDDs), such as autism spectrum disorder (ASD) and attention–deficit/hyperactivity disorder. These examinations should include assessment for morphological variants. Previous studies have shown an increase in morphological variants in individuals with NDDs, particularly ASD, and that these variants may be present in greater amounts in individuals with genetic alterations....
Sun Mar 15, 2020 21:12
Abstract Warburg Micro syndrome and Martsolf syndrome are phenotypically overlapping autosomal recessive conditions characterized by multiple organ abnormalities involving the ocular, nervous, and endocrine systems. Warburg Micro syndrome, the more severe of the two conditions, is caused by loss of function mutations in RAB3GAP1, RAB3GAP2, RAB18, and TBC1D20 genes, whereas Martsolf syndrome has been attributed to less damaging mutations in RAB3GAP1 and RAB3GAP2 genes. We report the clinical description...
Sun Mar 15, 2020 21:12
Abstract PTEN hamartoma tumor syndrome (PHTS) is a spectrum of hereditary cancer syndromes caused by germline mutations in PTEN. PHTS is of high interest, because of its high rate of neurological comorbidities including macrocephaly, autism spectrum disorder, and intellectual dysfunction. Since detailed brain morphology and connectivity of PHTS remain unclear, we quantitatively evaluated brain magnetic resonance imaging (MRI) in PHTS. Sixteen structural T1‐weighted and 9 diffusion‐weighted MR images...
Sun Mar 15, 2020 21:12
Abstract The 40th Annual David W. Smith Workshop on Malformations and Morphogenesis occurred August 23rd ‐28th, 2019 at the Snowbird Resort in Snowbird, Utah. The Workshop, which honors the legacy of David W. Smith, brought together clinicians and researchers interested in congenital malformations and their underlying mechanisms of morphogenesis from around the world. In addition to mechanisms of morphogenesis and delineation of new syndromes, the Workshop highlighted five themes: deformations,...
Sun Mar 15, 2020 21:12
Sun Mar 15, 2020 21:12
Sun Mar 15, 2020 21:12
Cover Image The cover image is based on the Case Report* Further delineation of the phenotypic spectrum of nevus comedonicus syndrome to include congenital pulmonary airway malformation of the lung and aneurysm by Sarah Sheppard et al., https://doi.org/10.1002/ajmg.a.61490.
Sun Mar 15, 2020 21:12
Abstract Melanogenesis, migration, and proliferation of melanocytes are important factors that determine the hair colors of mammals. MicroRNAs (miRNAs) have been shown to be closely relation to these processes. In melanocytes of alpacas, insulin‐like growth factor 1 (IGF1) has been shown to improve melanogenesis through the cyclic AMP (cAMP) pathway. miR‐379 was predicted to target insulin‐like growth factor (IGF) receptor 1 (IGF1R), which binds to IGF1. Therefore, we hypothesized that miR‐379...
Sun Mar 15, 2020 21:05
Publication date: Available online 14 March 2020Source: Journal of VoiceAuthor(s): Shenbagavalli Mahalingam, Prakash Boominathan, Ravikumar Arunachalam, Lakshmi Venkatesh, Sreya Srinivas
Sun Mar 15, 2020 20:22
Publication date: Available online 14 March 2020Source: Journal of VoiceAuthor(s): Ricardo Cardoso, Rute F. Meneses, José Lumini-Oliveira, Pedro Pestana, Bruno Guimarães
Sat Mar 14, 2020 13:33
Publication date: Available online 13 March 2020Source: Journal of VoiceAuthor(s): Shintaro Fujimura, Tsuyoshi Kojima, Yusuke Okanoue, Kazuhiko Shoji, Masato Inoue, Koichi Omori, Ryusuke Hori
Fri Mar 13, 2020 19:23
Publication date: Available online 12 March 2020Source: Journal of VoiceAuthor(s): Peter S. Popolo, Aaron M. Johnson
Fri Mar 13, 2020 19:23
Publication date: Available online 12 March 2020Source: Journal of VoiceAuthor(s): Emel Tahir, Esra Kavaz, Özlem Cangökçe Yaşar
Fri Mar 13, 2020 19:23
Publication date: Available online 14 March 2020Source: Hearing ResearchAuthor(s): Xin Luo, Christopher Garrett
Sun Mar 15, 2020 20:11
Publication date: April 2020Source: Hearing Research, Volume 389Author(s):
Sat Mar 14, 2020 18:59
Abstract Health professions preventing and controlling Coronavirus Disease 2019 are prone to skin and mucous membrane injury, which may cause acute and chronic dermatitis, secondary infection and aggravation of underlying skin diseases. This is a consensus of Chinese experts on protective measures and advice on hand‐cleaning‐ and medical‐glove‐related hand protection, mask‐ and goggles‐related face protection, UV‐related protection, eye protection, nasal and oral mucosa protection, outer ear and...
Sun Mar 15, 2020 19:16
Abstract Objective Neuronal loss in the substantia nigra pars compacta (SNpc) in Parkinson's disease (PD) is not uniform as dopamine neurons from the ventral tier are lost more rapidly than those of the dorsal tier. Identifying the intrinsic differences that account for this differential vulnerability may provide a key for developing new treatments for PD. Method Here we compared the RNA‐sequenced transcriptomes of ~100 laser captured micro‐dissected SNpc neurons from each tier from...
Sun Mar 15, 2020 19:13
Publication date: Available online 14 March 2020Source: CortexAuthor(s): Stephanie D. Preston, Melanie Ermler, Yuqing Lei, Logan Bickel
Sun Mar 15, 2020 19:09
Publication date: Available online 14 March 2020Source: CortexAuthor(s): Daniel Zachlod, Britta Rüttgers, Sebastian Bludau, Hartmut Mohlberg, Robert Langner, Karl Zilles, Katrin Amunts
Sun Mar 15, 2020 19:09
Publication date: Available online 13 March 2020Source: CortexAuthor(s): Monika Halicka, Axel D. Vittersø, Hayley McCullough, Andreas Goebel, Leila Heelas, Michael J. Proulx, Janet H. Bultitude
Sat Mar 14, 2020 16:32
We evaluated the relationship between patient-, tumor-, and treatment-related features and radiation-induced lymphopenia (RIL) and evaluated the correlation between RIL and survival outcome in NPC patients to ...
Sat Mar 14, 2020 02:00
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