Antibody-modified magnetic nanoparticles as specific high-efficient cell-separation agents. J Biomed Mater Res B Appl Biomater. 2020 Mar 14;: Authors: Saei A, Asfia S, Kouchakzadeh H, Rahmandoust M Abstract Separation of tumor cells is a promising approach that helps not only in early detection of cancer but also as an efficient tool that holds great importance in prohibiting cancer cell mutation, drug resistance to treatments, and in granting successful...
Sun Mar 15, 2020 14:31
Related ArticlesImaging and monitoring HER2 expression in breast cancer during trastuzumab therapy with a peptide probe 99mTc-HYNIC-H10F. Eur J Nucl Med Mol Imaging. 2020 Mar 13;: Authors: Wu Y, Li L, Wang Z, Shi J, Hu Z, Gao S, Miao W, Ma Q, Dong C, Wang F Abstract PURPOSE: The novel molecular imaging probe 99mTc-HYNIC-H10F was developed for patient screening and efficacy monitoring of trastuzumab therapy by SPECT imaging of HER2 expression in breast...
Sun Mar 15, 2020 14:31
Human sex chromosome aneuploidies: The hypothalamic-pituitary-gonadal axis. Am J Med Genet C Semin Med Genet. 2020 Mar 14;: Authors: Rogol AD Abstract Sex chromosome aneuploidies (SCA) are relatively common as a group, perhaps 1 per 500 births, but much more common at conception. Many syndromes have been noted in those with these conditions, but not so many data are available concerning the hypothalamic-pituitary-gonadal (HPG) axis. The physiology of...
Sun Mar 15, 2020 14:27
Related ArticlesExploring the diversity of sugar compounds in healthy, prediabetic and diabetic volunteers. Mol Nutr Food Res. 2020 Mar 13;:e1901190 Authors: Mack CI, Ferrario PG, Weinert CH, Egert B, Hoefle AS, Lee YM, Skurk T, Kulling SE, Daniel H Abstract SCOPE: Diabetes is thought to primarily represent a disturbance of carbohydrate metabolism; however, population studies employing metabolomics have mainly identified plasma amino acids and lipids,...
Sun Mar 15, 2020 14:27
Related ArticlesThe exercise pressor reflex and chemoreflex interaction: cardiovascular implications for the exercising human. J Physiol. 2020 Mar 14;: Authors: Wan HY, Weavil JC, Thurston TS, Georgescu VP, Hureau TJ, Bledsoe AD, Buys MJ, Jessop JE, Richardson RS, Amann M Abstract KEY POINTS: Although the exercise pressor reflex (EPR) and the chemoreflex (CR) are recognized for their sympathoexcitatory effect, the cardiovascular implication of their...
Sun Mar 15, 2020 14:27
Related ArticlesMMP9 mediates acute hyperglycemia-induced human cardiac stem cell death by upregulating apoptosis and pyroptosis in vitro. Cell Death Dis. 2020 Mar 13;11(3):186 Authors: Yadav SK, Kambis TN, Kar S, Park SY, Mishra PK Abstract Providing a conducive microenvironment is critical to increase survival of transplanted stem cells in regenerative therapy. Hyperglycemia promotes stem cell death impairing cardiac regeneration in the diabetic heart....
Sun Mar 15, 2020 14:27
Related ArticlesGlobal trends of hand and wrist trauma: a systematic analysis of fracture and digit amputation using the Global Burden of Disease 2017 Study. Inj Prev. 2020 Mar 13;: Authors: Crowe CS, Massenburg BB, Morrison SD, Chang J, Friedrich JB, Abady GG, Alahdab F, Alipour V, Arabloo J, Asaad M, Banach M, Bijani A, Borzì AM, Briko NI, Castle CD, Cho DY, Chung MT, Daryani A, Demoz GT, Dingels ZV, Do HT, Fischer F, Fox JT, Fukumoto T, Gebre AK, Gebremichael B, Haagsma...
Sun Mar 15, 2020 14:27
Related ArticlesMicroencapsulated G3C hybridoma cell graft delays the onset of spontaneous diabetes in NOD mice by an expansion of Gitr+ Treg cells. Diabetes. 2020 Mar 13;: Authors: Cari L, Montanucci P, Basta G, Petrillo MG, Ricci E, Pescara T, Greco A, Cipriani S, Shimizu J, Migliorati G, Nocentini G, Calafiore R, Riccardi C Abstract As an alternative to lifelong insulin supplementation, potentiation of immune tolerance in type 1 diabetes patients...
Sun Mar 15, 2020 14:27
Related ArticlesStromal-Mdm2 promotes lung cancer cell invasion through tumor-host feedback signaling. Mol Cancer Res. 2020 Mar 13;: Authors: Kamer I, Daniel-Meshulam I, Zadok O, Bab-Dinitz E, Perry G, Feniger-Barish R, Perelman M, Barshack I, Ben-Nun A, Onn A, Bar J Abstract Tumor-host interactions play a major role in malignancies' initiation and progression. We have reported in the past that tumor cells attenuate genotoxic stress-induced p53 activation...
Sun Mar 15, 2020 14:27
Related ArticlesThe role of gut microbiota in bone homeostasis. Bone. 2020 Mar 10;:115317 Authors: Behera J, Ison J, Tyagi SC, Tyagi N Abstract The gut microbiota (GM) is referred to as the second gene pool of the human body and a commensal, symbiotic, and pathogenic microorganism living in our intestines. The knowledge of the complex interaction between intestinal microbiota and health outcomes is a novel and rapidly expanding the field. Earlier studies...
Sun Mar 15, 2020 14:27
Related ArticlesYeast recombinant production of intact human membrane proteins with long intrinsically disordered intracellular regions for structural studies. Biochim Biophys Acta Biomembr. 2020 Mar 10;:183272 Authors: Kassem N, Kassem MM, Pedersen SF, Pedersen PA, Kragelund BB Abstract Membrane proteins exist in lipid bilayers and mediate solute transport, signal transduction, cell-cell communication and energy conversion. Their activities are fundamental...
Sun Mar 15, 2020 14:27
Related ArticlesImpact of early life adversities on human brain functioning: a coordinate-based meta-analysis. Neurosci Biobehav Rev. 2020 Mar 10;: Authors: Kraaijenvanger EJ, Pollok TM, Monninger M, Kaiser A, Brandeis D, Banaschewski T, Holz NE Abstract The detrimental impact of early life adversities (ELAs; entailing pre-and postnatal experiences) on the developing brain has been well established. By inducing neural alterations underlying critical...
Sun Mar 15, 2020 14:27
Related ArticlesCreation of rapid and reproducible burn in animal model with a newly developed burn device. Burns. 2020 Mar 10;: Authors: Shukla SK, Sharma AK, Shaw P, Kalonia A, Yashavarddhan MH, Singh S Abstract BACKGROUND: The currently available practices for creation of burns in the animals are mostly manual which may lead to lack of uniform wound. There is a need to develop a suitable device that could reproduce and uniformly create burn wound...
Sun Mar 15, 2020 14:27
Related ArticlesUnderstanding vestibular-related physiological functions could provide clues on adapting to a new gravitational environment. J Physiol Sci. 2020 Mar 14;70(1):17 Authors: Morita H, Kaji H, Ueta Y, Abe C Abstract The peripheral vestibular organs are sensors for linear acceleration (gravity and head tilt) and rotation. Further, they regulate various body functions, including body stability, ocular movement, autonomic nerve activity, arterial...
Sun Mar 15, 2020 14:27
Related ArticlesA Novel Genetically Encoded Single Use Sensory Cellular Test System Measures Bicarbonate Concentration Changes in Living Cells. Sensors (Basel). 2020 Mar 11;20(6): Authors: Bernhard K, Stahl C, Martens R, Frey M Abstract Bicarbonate plays a central role in human physiology from cellular respiration to pH homeostasis. However, so far, the measurement of bicarbonate concentration changes in living cells has only been possible by measuring...
Sun Mar 15, 2020 14:27
Related ArticlesHuman Herpesvirus 8 and Host-Cell Interaction: Long-Lasting Physiological Modifications, Inflammation and Related Chronic Diseases. Microorganisms. 2020 Mar 11;8(3): Authors: Angius F, Ingianni A, Pompei R Abstract Oncogenic and latent-persistent viruses belonging to both DNA and RNA groups are known to cause serious metabolism alterations. Among these, the Human Herpesvirus 8 (HHV8) infection induces stable modifications in biochemistry...
Sun Mar 15, 2020 14:27
Related ArticlesAn Untargeted Metabolomics Approach to Investigate the Metabolic Effect of Beetroot Juice Supplementation in Fencers-A Preliminary Study. Metabolites. 2020 Mar 11;10(3): Authors: Kozlowska L, Mizera O, Mroz A Abstract This study aimed at assessment of the long-term (4 weeks) metabolic effect of a diet with and without beetroot juice supplementation in fencers using the untargeted metabolomics method with the UPLC Q-TOF/MS system to carry...
Sun Mar 15, 2020 14:27
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