Related ArticlesHepatic encephalopathy: a rare cause of focal seizures in chronic liver disease. BMJ Case Rep. 2020 Mar 12;13(3): Authors: Tern PJW, Bryce K, Marelli L, Ruban A Abstract Hepatic encephalopathy (HE) is an extremely rare cause of focal seizures and is usually a diagnosis of exclusion when more commoner causes such as infection, autoimmune and malignancy have been discounted. The literature reports patients with generalised cerebral oedema...
Sun Mar 15, 2020 13:57
Related ArticlesDeep brain stimulation of anterior thalamic nucleus for the treatment of a patient with tuberous sclerosis-related refractory epilepsy. World Neurosurg. 2020 Mar 10;: Authors: Zheng H, Chengcheng W, Bin J, Chaochao W, Hongying Z, Wenqiang G, Bin L, Hailong T, Zhigang W Abstract Neuromodulation is recommended for patients with refractory tuberous sclerosis related epilepsy (TRE) who are unable to localize epileptogenic nodules after comprehensive...
Sun Mar 15, 2020 13:57
Related ArticlesThe role of targeted gene panel in pediatric drug-resistant epilepsy. Epilepsy Behav. 2020 Mar 10;106:107003 Authors: Wu CC, Tsai MH, Chu YJ, Weng WC, Fan PC, Lee WT Abstract About 10-30% of pediatric patients with epilepsy have drug-resistant epilepsy. Genetic panels may be useful in identifying etiology and guiding treatment in pediatric patients with drug-resistant epilepsy. In our tertiary center, we used two epilepsy panels, an initial...
Sun Mar 15, 2020 13:57
Related ArticlesCannabidiol in treatment of refractory epileptic spasms: An open-label study. Epilepsy Behav. 2020 Mar 10;106:106988 Authors: Herlopian A, Hess EJ, Barnett J, Geffrey AL, Pollack SF, Skirvin L, Bruno P, Sourbron J, Thiele EA Abstract OBJECTIVE: This study aimed to evaluate clinical efficacy and safety of purified pharmaceutical cannabidiol (CBD) as an adjunctive therapy in refractory childhood-onset epileptic spasms (ES). METHODS:...
Sun Mar 15, 2020 13:57
Related ArticlesCognitive behavior therapy for comorbid dissociative seizures in patients with epilepsy. Epilepsy Behav. 2020 Mar 10;106:106993 Authors: Berry AJ, Yuksel M, Proctor BJ, Foong J Abstract OBJECTIVES: The main aim of this study was to assess the effectiveness of cognitive behavior therapy (CBT) for comorbid dissociative seizures (DS) in patients with epilepsy. METHODS: We conducted a retrospective case note review of 14 patients...
Sun Mar 15, 2020 13:57
Related ArticlesNonconvulsive status epilepticus in the elderly. Rev Neurol (Paris). 2020 Mar 10;: Authors: Dupont S, Kinugawa K Abstract There is a higher incidence of status epilepticus in the older adult population that commonly presents as nonconvulsive status epilepticus (NCSE). NCSE most often corresponds to prolonged focal seizures with impaired consciousness with three main clinical presentations: i) an unexplained acute confusional state, ii)...
Sun Mar 15, 2020 13:57
Related ArticlesPredictors of early postoperative epileptic seizures after awake surgery in supratentorial diffuse gliomas. J Neurosurg. 2020 Mar 13;:1-10 Authors: Zanello M, Roux A, Zah-Bi G, Trancart B, Parraga E, Edjlali M, Tauziede-Espariat A, Sauvageon X, Sharshar T, Oppenheim C, Varlet P, Dezamis E, Pallud J Abstract OBJECTIVE: Functional-based resection under awake conditions had been associated with a nonnegligible rate of intraoperative and...
Sat Mar 14, 2020 12:29
Related ArticlesKCNT1-related epilepsy: An international multicenter cohort of 27 pediatric cases. Epilepsia. 2020 Mar 13;: Authors: Borlot F, Abushama A, Morrison-Levy N, Jain P, Puthenveettil Vinayan K, Abukhalid M, Aldhalaan HM, Almuzaini HS, Gulati S, Hershkovitz T, Konanki R, Lingappa L, Luat AF, Shafi S, Tabarki B, Thomas M, Yoganathan S, Alfadhel M, Arya R, Donner EJ, Ehaideb SN, Gowda VK, Jain V, Madaan P, Myers KA, Otsubo H, Panda P, Sahu JK, Sampaio LPB, Sharma...
Sat Mar 14, 2020 12:29
Related ArticlesIn Vivo Imaging of Neuroinflammatory Targets in Treatment-Resistant Epilepsy. Curr Neurol Neurosci Rep. 2020 Mar 12;20(4):5 Authors: Sharma AA, Szaflarski JP Abstract PURPOSE OF REVIEW: Recent evidence indicates that chronic, low-level neuroinflammation underlies epileptogenesis. Targeted imaging of key neuroinflammatory cells, receptors, and tissues may enable localizing epileptogenic onset zone, especially in those patients who are...
Sat Mar 14, 2020 12:29
Related ArticlesHighly realistic simulation for robot-assisted hypothalamic hamartoma real-time MRI-guided laser interstitial thermal therapy (LITT). Childs Nerv Syst. 2020 Mar 12;: Authors: Candela-Cantó S, Alamar M, Aláez C, Muchart J, Forero C, de la Gala C, Munuera J, Serrano S, Quintillá JM, Hinojosa J Abstract PURPOSE: Real-time MRI-guided laser interstitial thermal therapy (LITT) is a challenging procedure due to its technical complexity, as well...
Sat Mar 14, 2020 12:29
Related ArticlesRole of vinpocetine in ischemic stroke and poststroke outcomes: A critical review. Brain Circ. 2020 Jan-Mar;6(1):1-10 Authors: Al-Kuraishy HM, Al-Gareeb AI, Naji MT, Al-Mamorry F Abstract Vinpocetine (VPN) is a synthetic ethyl-ester derivative of the alkaloid apovincamine from Vinca minor leaves. VPN is a selective inhibitor of phosphodiesterase type 1 (PDE1) that has potential neurological effects through inhibition of voltage-gated...
Sat Mar 14, 2020 12:29
Related ArticlesDravet Syndrome: A Review of Current Management. Pediatr Neurol. 2020 Jan 31;: Authors: Wheless JW, Fulton SP, Mudigoudar BD Abstract Dravet syndrome is a debilitating epileptic encephalopathy of childhood with few treatment options available in the United States before 2018. In the modern era, new genetic testing options will allow diagnosis closer to disease onset. Three new medicines-stiripentol, cannabidiol, and fenfluramine-have...
Sat Mar 14, 2020 12:29
Related ArticlesPerampanel for nonepileptic myoclonus in Angelman syndrome. Brain Dev. 2020 Mar 10;: Authors: Kawano O, Egawa K, Shiraishi H Abstract BACKGROUND: Angelman syndrome (AS) is a neurodegenerative disorder caused by functional loss of the maternal ubiquitin-protein ligase 3A gene. Nonepileptic myoclonus, also described as tremulous movement, often occurs during puberty and increases in adulthood. The involuntary movement in AS has not been...
Sat Mar 14, 2020 12:29
Related ArticlesSmart neuromodulation in movement disorders. Handb Clin Neurol. 2020;168:153-161 Authors: Mitchell KT, Starr PA Abstract Deep brain stimulation (DBS) is a technique for invasive subcortical neuromodulation using a totally implantable permanent device. DBS is an effective therapy for movement disorders and is under investigation for the treatment of many other conditions including Tourette syndrome, epilepsy, and depression. Traditional...
Sat Mar 14, 2020 12:29
Related ArticlesThe clinical value of long - term electroencephalogram (EEG) in seizure - free populations: implications from a cross-sectional study. BMC Neurol. 2020 Mar 12;20(1):88 Authors: Xinghua T, Lin L, Qinyi F, Yarong W, Zheng P, Zhenguo L Abstract BACKGROUD: This study aimed to explore the clinical value of long - term electroencephalogram (LTM EEG) in seizure-free individuals taking antiepileptic drugs (AEDs) for more than 2 years. We try...
Sat Mar 14, 2020 12:29
Related Articles[Clinical analysis of 7 cases with anti-Caspr2 antibody-associated autoimmune encephalitis]. Zhonghua Yi Xue Za Zhi. 2020 Feb 25;100(7):513-515 Authors: Guo YP, Li XY, Liu HF, Zhang M, Shi L, Zhao XJ, Li JZ, Liu XY, Cui J Abstract Objective: To investigate the clinical features, laboratory tests, imaging features, electroencephalogram (EEG) manifestations, treatment and prognosis of anti-CASPR2 antibody-associated autoimmune encephalitis...
Sat Mar 14, 2020 12:29
Related ArticlesKetogenic Diet: A New Light Shining on Old but Gold Biochemistry. Nutrients. 2019 Oct 17;11(10): Authors: Longo R, Peri C, Cricrì D, Coppi L, Caruso D, Mitro N, De Fabiani E, Crestani M Abstract Diets low in carbohydrates and proteins and enriched in fat stimulate the hepatic synthesis of ketone bodies (KB). These molecules are used as alternative fuel for energy production in target tissues. The synthesis and utilization of KB are tightly...
Sat Mar 14, 2020 12:29
Related ArticlesCortisol levels and seizures in adults with epilepsy: A systematic review. Neurosci Biobehav Rev. 2019 08;103:216-229 Authors: Cano-López I, González-Bono E Abstract Stress has been suggested as a trigger factor for seizures in epilepsy patients, but little is known about cortisol levels, as indicators of stress, in adults with epilepsy. This systematic review summarizes the evidence on this topic. Following PRISMA guidelines, 38 articles...
Sat Mar 14, 2020 12:29
Related ArticlesRecurrent Herpes Simplex Virus Encephalitis After Epilepsy Surgery. Can J Neurol Sci. 2019 03;46(2):261-263 Authors: Arnold A, Parkins MD, Hamilton LE, Hader W, Federico P PMID: 30665474 [PubMed - indexed for MEDLINE]
Sat Mar 14, 2020 12:29
Related ArticlesTrends in prevalence and treatment of depressive symptoms in adult patients with epilepsy in the United States. Epilepsy Behav. 2020 Mar 09;105:106973 Authors: Ajinkya S, Fox J, Lekoubou A Abstract OBJECTIVE: Depressive symptoms are a common comorbidity among adults with epilepsy (AWE). Prior estimates regarding prevalence and treatment of depressive symptoms in AWE have been largely based on samples of tertiary care cohorts that may...
Fri Mar 13, 2020 14:01
Related ArticlesTreatment of epilepsy in adults: Expert opinion in South Korea. Epilepsy Behav. 2020 Mar 09;105:106942 Authors: Byun JI, Kim DW, Kim KT, Yang KI, Lee ST, Seo JG, No YJ, Kang KW, Kim D, Kim JM, Cho YW, Drug Committee of Korean Epilepsy Society Abstract OBJECTIVE: The aim of this study was to gather the expert opinions of Korean epileptologists regarding the treatment of adult patients with epilepsy. METHODS: A total of 42 neurologists...
Fri Mar 13, 2020 14:01
Related ArticlesEvaluation of psychomotor functions in patients with drug-resistant epilepsy. Epilepsy Behav. 2020 Mar 09;106:106985 Authors: Mathon B, Bordes A, Amelot A, Carpentier A, Méré M, Dupont S, Samson S Abstract PURPOSE: This study aimed to describe and analyze psychomotor functions in patients with drug-resistant epilepsy and identify factors associated with psychomotor deficits. METHODS: We performed a prospective case-control study...
Fri Mar 13, 2020 14:01
Related ArticlesNot your parents' ketogenic diet - Flexibility in 2020. Epilepsy Res. 2020 Mar 04;162:106307 Authors: Blackford R Abstract This is a commentary on the details of the increasing flexibility of the original classic ketogenic diet, a well-known evidence-based treatment option for intractable epilepsy. The variety of ketogenic diet therapies (KDT) have shown similar efficacy to the classic version. Initiation protocols, outpatient diet starts,...
Fri Mar 13, 2020 14:01
Related ArticlesThe treatment outcomes of epilepsy and its root causes in children attending at the University of Gondar teaching hospital: A retrospective cohort study, 2018. PLoS One. 2020;15(3):e0230187 Authors: Beyene A, Ayalew AF, Mulat G, Simachew Kassa A, Birhan T Abstract BACKGROUND: Epilepsy is the most common chronic neurologic disorder which affects an estimated 10.5 million children worldwide. Despite the burden, the scarcity of study held...
Fri Mar 13, 2020 14:01
Related ArticlesRole of Glia in the Regulation of Sleep in Health and Disease. Compr Physiol. 2020 Mar 12;10(2):687-712 Authors: Garofalo S, Picard K, Limatola C, Nadjar A, Pascual O, Tremblay MÈ Abstract Sleep is a naturally occurring physiological state that is required to sustain physical and mental health. Traditionally viewed as strictly regulated by top-down control mechanisms, sleep is now known to also originate locally. Glial cells are emerging...
Fri Mar 13, 2020 14:01
Related ArticlesCircadian and multiday seizure periodicities, and seizure clusters in canine epilepsy. Brain Commun. 2020;2(1):fcaa008 Authors: Gregg NM, Nasseri M, Kremen V, Patterson EE, Sturges BK, Denison TJ, Brinkmann BH, Worrell GA Abstract Advances in ambulatory intracranial EEG devices have enabled objective analyses of circadian and multiday seizure periodicities, and seizure clusters in humans. This study characterizes circadian and multiday...
Fri Mar 13, 2020 12:31
Related ArticlesTargeted Infarction of the Internal Capsule in the Rat Using Microstimulation Guidance. Stroke. 2019 09;50(9):2531-2538 Authors: Wen TC, Sindhurakar A, Ramirez VC, Park H, Gupta D, Carmel JB Abstract Background and Purpose- Lacunar strokes are subcortical infarcts with small size and high disability rates, largely due to injury of the corticospinal tract in the internal capsule (IC). Current rodent models of lacunar infarcts are created...
Fri Mar 13, 2020 12:31
Related ArticlesAssessment of School-Aged Children of Mothers With Idiopathic Generalized Epilepsy. J Nerv Ment Dis. 2019 10;207(10):863-868 Authors: Kishk N, Hassan A, Madbouly N, Nawito A, Maher E, Heneidy S Abstract The aim is to examine the cognitive domains, behavioral domains, and electroencephalogram (EEG) findings in children of mothers with idiopathic generalized epilepsy who had been exposed to antiepileptic drugs (AEDs) in utero. Forty school-aged...
Fri Mar 13, 2020 12:31
Related ArticlesThree-dimensional neuronavigation in SEEG-guided epilepsy surgery. Acta Neurochir (Wien). 2019 05;161(5):917-923 Authors: Minkin K, Gabrovski K, Sirakov S, Penkov M, Todorov Y, Karakostov V, Dimova P Abstract OBJECTIVES: Epilepsy surgery is mainly cortical surgery and the precise definition of the epileptogenic zone on the complex cortical surface is of paramount importance. Stereoelectroencephalography (SEEG) may delineate the epileptogenic...
Fri Mar 13, 2020 12:31
Related ArticlesScreening spreading depolarizations during epilepsy surgery. Acta Neurochir (Wien). 2019 05;161(5):911-916 Authors: Santos E, Dávila-Rodríguez DO, Márquez-Gonzalez K, Díaz-Peregrino R, Alonso-Vanegas M, Olivares-Rivera A, Anschel D, San-Juan D Abstract BACKGROUND: Spreading depolarization (SD) is a fundamental pathophysiological mechanism of both pannecrotic and selective neuronal lesions following deprivation of energy. SD with brain...
Fri Mar 13, 2020 12:31
Related ArticlesIn Vivo Models for Pathotyping and Vaccine Efficacy for Swine Influenza. Methods Mol Biol. 2020;2123:345-351 Authors: Lager KM, Vincent AL Abstract Swine influenza is a disease of the respiratory tract caused by influenza A virus (IAV). Experimental inoculation of pigs involves either aerosolization of virus and inhalation or the direct introduction of virus into the upper or lower respiratory tract. This chapter covers methods for...
Sun Mar 15, 2020 13:57
Related ArticlesClinical characteristics for conservative therapy of pediatric parapharyngeal abscesses. Braz J Otorhinolaryngol. 2019 Dec 23;: Authors: Bi J, Chen X, Zhou Z, Fu Y Abstract INTRODUCTION: The role of surgical drainage versus conservative therapy in treating patients with parapharyngeal abscesses is still a theme of debate. OBJECTIVES: This study aimed to investigate the characteristics associated with good outcomes in pediatric...
Sun Mar 15, 2020 13:57
Related ArticlesOral management of a patient with down syndrome and agammaglobulinemia: a case report. BMC Oral Health. 2020 Mar 13;20(1):71 Authors: Kusumoto Y, Imai K, Ohyama Y, Fukayama H, Shinozuka O Abstract BACKGROUND: Down syndrome is characterized by a variety of dysmorphic features and congenital malformations, such as congenital heart disease, gastrointestinal disease, and other conditions like leukemia and autoimmune disorders. Patients...
Sun Mar 15, 2020 13:57
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