Antibiotics, Vol. 9, Pages 141: Single Blinded Study on the Feasibility of Decontaminating LA-MRSA in Pig Compartments under Routine Conditions Antibiotics doi: 10.3390/antibiotics9040141 Authors: Kobusch Müller Mellmann Köck Boelhauve ： In countries with intensive pig husbandry in stables, the prevalence of livestock-associated (LA) methicillin-resistant Staphylococcus aureus (MRSA) on such farms has remained high in the last few years or has also further increased....
Thu Mar 26, 2020 02:00
Antibiotics, Vol. 9, Pages 142: Antibacterial Peptides Antibiotics doi: 10.3390/antibiotics9040142 Authors: Sabatier As natural host defense compounds produced by numerous prokaryotic and eukaryotic life forms, antimicrobial peptides (AMPs) are now emerging as solid candidate chemotherapeutic drugs to fight against the various types of pathogenic Gram-positive and Gram-negative bacteria, especially those resistant to current antibiotics [...]
Thu Mar 26, 2020 02:00
Antibodies, Vol. 9, Pages 8: Fast Confirmation of Antibody Identity by MALDI-TOF MS Fingerprints Antibodies doi: 10.3390/antib9020008 Authors: Tscheuschner Schwaar Weller Thousands of antibodies for diagnostic and other analytical purposes are on the market. However, it is often difficult to identify duplicates, reagent changes, and to assign the correct original publications to an antibody. This slows down scientific progress and might even be a cause of irreproducible research...
Thu Mar 26, 2020 02:00
Antioxidants, Vol. 9, Pages 281: Effect of Natural Preservatives on the Nutritional Profile, Chemical Composition, Bioactivity and Stability of a Nutraceutical Preparation of Aloe arborescens Antioxidants doi: 10.3390/antiox9040281 Authors: Filipa A. Fernandes Márcio Carocho Sandrina A. Heleno Paula Rodrigues Maria Inês Dias José Pinela Miguel A. Prieto Jesus Simal-Gandara Lillian Barros Isabel C. F. R. Ferreira Citric acid, quercetin, dried chestnut flowers...
Thu Mar 26, 2020 02:00
Antioxidants, Vol. 9, Pages 279: Ginkgo biloba Prevents Oxidative Stress-Induced Apoptosis Blocking p53 Activation in Neuroblastoma Cells Antioxidants doi: 10.3390/antiox9040279 Authors: Di Meo Cuciniello Margarucci Bergamo Petillo Peluso Filosa Crispi Oxidative stress has been associated to neuronal cell loss in neurodegenerative diseases. Neurons are post-mitotic cells that are very sensitive to oxidative stress—especially considering their limited...
Thu Mar 26, 2020 02:00
Antioxidants, Vol. 9, Pages 278: Development of Multifunctional Cosmetic Cream Using Bioactive Materials from Streptomyces sp. T65 with Synthesized Mesoporous Silica Particles SBA-15 Antioxidants doi: 10.3390/antiox9040278 Authors: Dahal Nguyen Shim Kim Lee Kim Various cosmetics having a single function are increasingly being used, but cosmetics having multifunctional activities remain limited. We aimed to develop a multifunctional cosmetic cream having antioxidant,...
Thu Mar 26, 2020 02:00
Antioxidants, Vol. 9, Pages 277: Impact of Ultrasound Extraction Parameters on the Antioxidant Properties of Moringa Oleifera Leaves Antioxidants doi: 10.3390/antiox9040277 Authors: Pollini Tringaniello Ianni Blasi Manes Cossignani Recently, much interest has been focused on Moringa oleifera L., a highly versatile and sustainable plant. In addition to its nutritional properties, numerous bioactive compounds have been identified in M. oleifera leaves, for which healthy...
Thu Mar 26, 2020 02:00
Antioxidants, Vol. 9, Pages 280: The Role of Hydrogen Peroxide and Peroxiredoxins throughout the Cell Cycle Antioxidants doi: 10.3390/antiox9040280 Authors: Heo Kim Kang Hydrogen peroxide (H2O2) is an oxidizing agent that induces cellular damage at inappropriate concentrations and gives rise to an arrest during cell cycle progression, causing cell death. Recent evidence indicates that H2O2 also acts as a promoter for cell cycle progression by oxidizing specific thiol proteins....
Thu Mar 26, 2020 02:00
Arts, Vol. 9, Pages 42: The National, the Diasporic, and the Canonical: The Place of Diasporic Imagery in the Canon of Israeli National Art Arts doi: 10.3390/arts9020042 Authors: Avron Barak This article explores Jerusalem-based art practice from the 1930s to the 1960s, focusing particularly on the German immigrant artists that dominated this field in that period. I describe the distinct aesthetics of this art and explain its role in the Zionist nation-building project. Although Jerusalem’s...
Thu Mar 26, 2020 02:00
Arts, Vol. 9, Pages 41: View Magazine and the Mass Visual Culture of World War II Arts doi: 10.3390/arts9020041 Authors: Gilbert Shortly after the bombing of Pearl Harbor in December of 1941, the American government impressed upon the media industry and corporate advertising the cooperative need to boost morale and enlist nationalist support for the war effort. Public opinion was shaped through an active campaign of visual propaganda and media censorship in which the social trauma of...
Thu Mar 26, 2020 02:00
Atmosphere, Vol. 11, Pages 320: pH- and Temperature-Dependent Kinetics of the Oxidation Reactions of OH with Succinic and Pimelic Acid in Aqueous Solution Atmosphere doi: 10.3390/atmos11040320 Authors: Schaefer Wen Estelmann Maak Herrmann Rate constants for the aqueous-phase reactions of the hydroxyl radical with the dicarboxylic acids, succinic acid and pimelic acid were determined using the relative rate technique over the temperature range 287 K ≤ T ≤...
Thu Mar 26, 2020 02:00
Atmosphere, Vol. 11, Pages 321: RANS Simulation of Local Strong Sandstorms Induced by a Cold Pool with Vorticity Atmosphere doi: 10.3390/atmos11040321 Authors: He Gu Shui Liu Lu Zhang Zhang Yu Local strong sandstorms (LSSs) in northwestern China often occur suddenly in tens of minutes during the late afternoon and by dusk. Observations and theoretical studies have shown the trigger role of cold-air pools over desert areas for the occurrence of LSS. In this...
Thu Mar 26, 2020 02:00
Biomedicines, Vol. 8, Pages 69: Two-Step Size-Exclusion Nanofiltration of Prothrombin Complex Concentrate Using Nanocellulose-Based Filter Paper Biomedicines doi: 10.3390/biomedicines8040069 Authors: Manukyan Mantas Razumikhin Katalevsky Golubev Mihranyan Coagulation Factor IX-rich protrhombin complex concentrate (FIX-PCC) is a therapeutic biologic product that consists of a mixture of several human plasma-derived proteins, useful for treating hemophilia B. Due...
Thu Mar 26, 2020 02:00
Biomolecules, Vol. 10, Pages 504: UV-B Radiation Largely Promoted the Transformation of Primary Metabolites to Phenols in Astragalus mongholicus Seedlings Biomolecules doi: 10.3390/biom10040504 Authors: Liu Liu Abozeid Wu Guo Mu Tang : Ultraviolet-B (UV-B) radiation (280–320 nm) may induce photobiological stress in plants, activate the plant defense system, and induce changes of metabolites. In our previous work, we found that between the two Astragalus...
Thu Mar 26, 2020 02:00
Biomolecules, Vol. 10, Pages 503: Exploring Alzheimer’s Disease Molecular Variability via Calculation of Personalized Transcriptional Signatures Biomolecules doi: 10.3390/biom10040503 Authors: Dagan Flashner-Abramson Vasudevan Jubran Cohen Kravchenko-Balasha Despite huge investments and major efforts to develop remedies for Alzheimer’s disease (AD) in the past decades, AD remains incurable. While evidence for molecular and phenotypic variability in AD have...
Thu Mar 26, 2020 02:00
Biomolecules, Vol. 10, Pages 505: Variations in Circulating Active MMP-9 Levels During Renal Replacement Therapy Biomolecules doi: 10.3390/biom10040505 Authors: Rodríguez-Sánchez Navarro-García Aceves-Ripoll Abarca-Zabalía Susmozas-Sánchez Bada-Bosch Hernández Mérida-Herrero Andrés Praga Fernández-Ruiz Aguado Segura Ruilope Ruiz-Hurtado Renal replacement therapy (RRT) is complicated by a chronic state of inflammation and a high...
Thu Mar 26, 2020 02:00
Biomolecules, Vol. 10, Pages 500: Estrogen Receptors and Ubiquitin Proteasome System: Mutual Regulation Biomolecules doi: 10.3390/biom10040500 Authors: Kondakova Shashova Sidenko Astakhova Zakharova Sharova This review provides information on the structure of estrogen receptors (ERs), their localization and functions in mammalian cells. Additionally, the structure of proteasomes and mechanisms of protein ubiquitination and cleavage are described. According to the...
Thu Mar 26, 2020 02:00
Biomolecules, Vol. 10, Pages 501: BET Inhibitors Synergize with Carfilzomib to Induce Cell Death in Cancer Cells via Impairing Nrf1 Transcriptional Activity and Exacerbating the Unfolded Protein Response Biomolecules doi: 10.3390/biom10040501 Authors: Vangala Potluri Radhakrishnan Currently, proteasome inhibitors bortezomib, carfilzomib, and ixazomib are successfully used in clinics to treat multiple myeloma. However, these agents show limited efficacy against solid tumors....
Thu Mar 26, 2020 02:00
Biomolecules, Vol. 10, Pages 502: Luteolin-7-O-Glucoside Inhibits Oral Cancer Cell Migration and Invasion by Regulating Matrix Metalloproteinase-2 Expression and Extracellular Signal-Regulated Kinase Pathway Biomolecules doi: 10.3390/biom10040502 Authors: Velmurugan Lin Mahalakshmi Chuang Lin Lo Hsieh Chen Oral squamous cell carcinoma is the sixth most common type of cancer globally, which is associated with high rates of cancer-related deaths. Metastasis...
Thu Mar 26, 2020 02:00
Brain Sciences, Vol. 10, Pages 196: Early Mortality of Brain Infarction Patients and Red Blood Cell Distribution Width Brain Sciences doi: 10.3390/brainsci10040196 Authors: Lorente Martín Abreu-González Pérez-Cejas González-Rivero Ramos-Gómez Argueso Solé-Violán Cáceres Jiménez García-Marín Background: Meta-analysis has found that high baseline red blood cell distribution width (RDW) is associated with increased long-term mortality (mortality...
Thu Mar 26, 2020 02:00
Cancers, Vol. 12, Pages 800: A Nine-Gene Signature for Predicting the Response to Preoperative Chemoradiotherapy in Patients with Locally Advanced Rectal Cancer Cancers doi: 10.3390/cancers12040800 Authors: In Ja Park Yun Suk Yu Bilal Mustafa Jin Young Park Yong Bae Seo Gun-Do Kim Jinpyo Kim Chang Min Kim Hyun Deok Noh Seung-Mo Hong Yeon Wook Kim Mi-Ju Kim Adnan Ahmad Ansari Luigi Buonaguro Sung-Min Ahn Chang-Sik Yu Preoperative chemoradiotherapy...
Thu Mar 26, 2020 02:00
Cancers, Vol. 12, Pages 799: Ionizing Radiation and Complex DNA Damage: Quantifying the Radiobiological Damage Using Monte Carlo Simulations Cancers doi: 10.3390/cancers12040799 Authors: Konstantinos P. Chatzipapas Panagiotis Papadimitroulas Dimitris Emfietzoglou Spyridon A. Kalospyros Megumi Hada Alexandros G. Georgakilas George C. Kagadis Ionizing radiation is a common tool in medical procedures. Monte Carlo (MC) techniques are widely used when dosimetry is the matter...
Thu Mar 26, 2020 02:00
Cancers, Vol. 12, Pages 798: External Beam Radiation Therapy and Enadenotucirev: Inhibition of the DDR and Mechanisms of Radiation-Mediated Virus Increase Cancers doi: 10.3390/cancers12040798 Authors: Tzveta D. Pokrovska Egon J. Jacobus Rathi Puliyadi Remko Prevo Sally Frost Arthur Dyer Richard Baugh Gonzalo Rodriguez-Berriguete Kerry Fisher Giovanna Granata Katharine Herbert William K. Taverner Brian R. Champion Geoff S. Higgins Len W. Seymour Janet...
Thu Mar 26, 2020 02:00
Cancers, Vol. 12, Pages 797: Artificial Intelligence and Digital Microscopy Applications in Diagnostic Hematopathology Cancers doi: 10.3390/cancers12040797 Authors: Hanadi El El Achi Joseph D. Khoury Digital Pathology is the process of converting histology glass slides to digital images using sophisticated computerized technology to facilitate acquisition, evaluation, storage, and portability of histologic information. By its nature, digitization of analog histology data renders it...
Thu Mar 26, 2020 02:00
Cancers, Vol. 12, Pages 796: Risk of Alzheimer’s Disease in Cancer Patients: Analysis of Mortality Data from the US SEER Population-Based Registries Cancers doi: 10.3390/cancers12040796 Authors: Roman Mezencev Yury O. Chernoff Previous studies have reported an inverse association between cancer and Alzheimer’s disease (AD), which are leading causes of human morbidity and mortality. We analyzed the SEER (Surveillance, Epidemiology, and End Results) data to estimate the risk...
Thu Mar 26, 2020 02:00
Cancers, Vol. 12, Pages 794: Treatment of Combined Hepatocellular and Cholangiocarcinoma Cancers doi: 10.3390/cancers12040794 Authors: Simona Leoni Vito Sansone Stefania De Lorenzo Luca Ielasi Francesco Tovoli Matteo Renzulli Rita Golfieri Daniele Spinelli Fabio Piscaglia Combined hepatocellular and cholangiocarcinoma (HCC-CC) is a rare primary liver cancer. It is constituted by neoplastic cells of both hepatocellular and cholangiocellular derivation. Different...
Thu Mar 26, 2020 02:00
Cancers, Vol. 12, Pages 793: Safety and Activity of the Combination of Ceritinib and Dasatinib in Osteosarcoma Cancers doi: 10.3390/cancers12040793 Authors: Olaf Beck Claudia Paret Alexandra Russo Jürgen Burhenne Margaux Fresnais Kevin Steimel Larissa Seidmann Daniel-Christoph Wagner Nadine Vewinger Nadine Lehmann Maximilian Sprang Nora Backes Lea Roth Marie Astrid Neu Arthur Wingerter Nicole Henninger Khalifa El Malki Henrike Otto Francesca...
Thu Mar 26, 2020 02:00
Cancers, Vol. 12, Pages 792: Analysis of HPV-Positive and HPV-Negative Head and Neck Squamous Cell Carcinomas and Paired Normal Mucosae Reveals Cyclin D1 Deregulation and Compensatory Effect of Cyclin D2 Cancers doi: 10.3390/cancers12040792 Authors: Jiří Novotný Veronika Bandúrová Hynek Strnad Martin Chovanec Miluše Hradilová Jana Šáchová Martin Šteffl Josipa Grušanović Roman Kodet Václav Pačes Lukáš Lacina Karel Smetana Jr. Jan Plzák Michal Kolář Tomáš...
Thu Mar 26, 2020 02:00
Cancers, Vol. 12, Pages 795: Tetraspanin CD9 is Regulated by miR-518f-5p and Functions in Breast Cell Migration and In Vivo Tumor Growth Cancers doi: 10.3390/cancers12040795 Authors: Danielle R. Bond Richard Kahl Joshua S. Brzozowski Helen Jankowski Crystal Naudin Mamta Pariyar Kelly A. Avery-Kiejda Christopher J. Scarlett Claude Boucheix William J. Muller Leonie K. Ashman Murray J. Cairns Séverine Roselli Judith Weidenhofer Breast cancer is the...
Thu Mar 26, 2020 02:00
Cancers, Vol. 12, Pages 790: Proteomic Discovery of Biomarkers to Predict Prognosis of High-Grade Serous Ovarian Carcinoma Cancers doi: 10.3390/cancers12040790 Authors: Se Ik Kim Minsun Jung Kisoon Dan Sungyoung Lee Cheol Lee Hee Seung Kim Hyun Hoon Chung Jae-Weon Kim Noh Hyun Park Yong-Sang Song Dohyun Han Maria Lee Initial identification of biomarkers predicting the exact prognosis of high-grade serous ovarian carcinoma (HGSOC) is important in precision...
Thu Mar 26, 2020 02:00
Cancers, Vol. 12, Pages 791: Embolotherapeutic Strategies for Hepatocellular Carcinoma: 2020 Update Cancers doi: 10.3390/cancers12040791 Authors: Sirish A. Kishore Raazi Bajwa David C. Madoff Hepatocellular carcinoma (HCC) represents a significant contributor to cancer-related morbidity and mortality with increasing incidence in both developing and developed countries. Embolotherapy as a locoregional therapeutic strategy consists of trans-arterial or “bland”...
Thu Mar 26, 2020 02:00
Cancers, Vol. 12, Pages 788: Dysregulated Pyrimidine Biosynthesis Contributes to 5-FU Resistance in SCLC Patient-Derived Organoids but Response to a Novel Polymeric Fluoropyrimidine, CF10 Cancers doi: 10.3390/cancers12040788 Authors: William H. Gmeiner Lance D. Miller Jeff W. Chou Anthony Dominijanni Lysette Mutkus Frank Marini Jimmy Ruiz Travis Dotson Karl W. Thomas Graham Parks Christina R. Bellinger Chemo-immunotherapy is central to the treatment of small...
Thu Mar 26, 2020 02:00
Cancers, Vol. 12, Pages 789: Blood Free-Circulating DNA Testing of Methylated RUNX3 Is Useful for Diagnosing Early Gastric Cancer Cancers doi: 10.3390/cancers12040789 Authors: Eizaburou Hideura Yutaka Suehiro Jun Nishikawa Takuya Shuto Hiroyuki Fujimura Shunsuke Ito Atsushi Goto Kouichi Hamabe Issei Saeki Takeshi Okamoto Shingo Higaki Ikuei Fujii Chieko Suzuki Tomomi Hoshida Toshihiko Matsumoto Taro Takami Isao Sakaida Takahiro Yamasaki ...
Thu Mar 26, 2020 02:00
Cancers, Vol. 12, Pages 786: A Novel Role for the Tumor Suppressor Gene ITF2 in Tumorigenesis and Chemotherapy Response Cancers doi: 10.3390/cancers12040786 Authors: Olga Pernía Ana Sastre-Perona Carlos Rodriguez-Antolín Alvaro García-Guede María Palomares-Bralo Rocío Rosas Darío Sanchez-Cabrero Patricia Cruz Carmen Rodriguez MDolores Diestro Rubén Martín-Arenas Verónica Pulido Pilar Santisteban Javier de Castro Olga Vera Inmaculada Ibáñez de Cáceres...
Thu Mar 26, 2020 02:00
Cancers, Vol. 12, Pages 785: Evaluation of Two EGFR Mutation Tests on Tumor and Plasma from Patients with Non-Small Cell Lung Cancer Cancers doi: 10.3390/cancers12040785 Authors: Jeong-Oh Kim Jung-Young Shin Seo Ree Kim Kab Soo Shin Joori Kim Min-Young Kim Mi-Ran Lee Yonggoo Kim Myungshin Kim Sook Hee Hong Jin Hyoung Kang Epidermal growth factor receptor (EGFR) mutation testing is essential for individualized treatment using tyrosine kinase inhibitors. We...
Thu Mar 26, 2020 02:00
Cancers, Vol. 12, Pages 787: mTORC2/Rac1 Pathway Predisposes Cancer Aggressiveness in IDH1-Mutated Glioma Cancers doi: 10.3390/cancers12040787 Authors: Yang Liu Yanxin Lu Aiguo Li Orieta Celiku Sue Han Mingyu Qian Chunzhang Yang Isocitrate dehydrogenase (IDH) mutations are common genetic abnormalities in lower grade gliomas. The neomorphic enzyme activity of IDH mutants leads to tumor formation through epigenetic alteration, dysfunction of dioxygenases, and metabolic...
Thu Mar 26, 2020 02:00
Cells, Vol. 9, Pages 806: Galectin-1 Overexpression Activates the FAK/PI3K/AKT/mTOR Pathway and Is Correlated with Upper Urinary Urothelial Carcinoma Progression and Survival Cells doi: 10.3390/cells9040806 Authors: Yu-Li Su Hao-Lun Luo Chun-Chieh Huang Ting-Ting Liu Eng-Yen Huang Ming-Tse Sung Jen-Jie Lin Po-Hui Chiang Yen-Ta Chen Chih-Hsiung Kang Yuan-Tso Cheng Galectin-1 (GAL1) is a β-galactoside-binding protein involved in multiple aspects of...
Thu Mar 26, 2020 02:00
Cells, Vol. 9, Pages 805: Autophagy Modulators Profoundly Alter the Astrocyte Cellular Proteome Cells doi: 10.3390/cells9040805 Authors: Affan Ali Sher Ang Gao Kevin M. Coombs Autophagy is a key cellular process that involves constituent degradation and recycling during cellular development and homeostasis. Autophagy also plays key roles in antimicrobial host defense and numerous pathogenic organisms have developed strategies to take advantage of and/or modulate cellular autophagy....
Thu Mar 26, 2020 02:00
Cells, Vol. 9, Pages 798: TNFa and IL2 Encoding Oncolytic Adenovirus Activates Pathogen and Danger-Associated Immunological Signaling Cells doi: 10.3390/cells9040798 Authors: Camilla Heiniö Riikka Havunen Joao Santos Klaas de Lint Victor Cervera-Carrascon Anna Kanerva Akseli Hemminki In order to break tumor resistance towards traditional treatments, we investigate the response of tumor and immune cells to a novel, cytokine-armed oncolytic adenovirus: Ad5/3-d24-E2F-hTNFa-IRES-hIL2...
Thu Mar 26, 2020 02:00
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