Πέμπτη 26 Μαρτίου 2020


Symptomatic scalp fistula present in a 14-month-old toddler
This case report covers the resection of a pulsatile scalp fistula, in a 14-month-old toddler. We discuss the patient diagnosis, imaging techniques used, as well as the patient’s surgical intervention. We highlight the aetiology of arteriovenous fistulas, while comparing and contrasting previous case reports and their interventions, to our own specific case.
BMJ Case Reports Last 6 Issues
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Iatrogenic post-pulpectomy cervicofacial subcutaneous emphysema in a paediatric patient
BMJ Case Reports Last 6 Issues
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Walled-off pancreatic necrosis: a staged multidisciplinary step-up approach
Walled-off pancreatic necrosis (WOPN) is a rare complication of pancreatitis. We present the case of a woman in her eighties admitted for diffuse abdominal pain. She had a palpable abdominal mass and the CT scan showed necrosis throughout the tail of the pancreas, a peripancreatic and retrogastric hydroaerial collection (19 cm of diameter) and a calculus in the main biliary duct, thus establishing a diagnosis of emphysematous necrotising obstructive pancreatitis. A step-up approach was decided, first...
BMJ Case Reports Last 6 Issues
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Disability-inclusive compassionate care: Disability competencies for an Indian Medical Graduate
Satendra Singh, Kamala Gullapalli Cotts, Khan Amir Maroof, Upreet Dhaliwal, Navjeevan Singh, Tao XieJournal of Family Medicine and Primary Care 2020 9(3):1719-1727 The new curriculum of the Medical Council of India (MCI) lacks disability-related competencies. This further involves the risk of perpetuating the medicalization of diverse human experiences and many medical students may graduate with little to no exposure to the principles of disability-inclusive compassionate care. Taking into consideration...
Journal of Family Medicine and Primary Care : 2014 - 3(3)
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Pain profile of premature infants during routine procedures in neonatal intensive care: An observational study
Arindrajit Ganguly, Pranav J Bhadesia, Ajay G Phatak, Archana S Nimbalkar, Somashekhar M NimbalkarJournal of Family Medicine and Primary Care 2020 9(3):1517-1521 Background: Premature neonates receive a large number of painful procedures during their stay in the neonatal intensive care unit (NICU). However, there are many other processes that happen in the NICU, which may not be considered painful but can cause discomfort and/or stress to the neonate. Method: Pain profile during routine procedures...
Journal of Family Medicine and Primary Care : 2014 - 3(3)
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Management of siblings with Glanzmann's thrombasthenia: A case report
Mebin George MathewJournal of Family Medicine and Primary Care 2020 9(3):1733-1735 Glanzmann's thrombasthenia is a rare, genetically inherited platelet disorder characterized by a lack of platelet aggregation. Until date, only close to 500 cases have been reported. GT is associated with clinical variability: some patients have only minimal bruising while others have frequent, severe and potentially fatal hemorrhages often making diagnosis difficult. Children are mostly diagnosed very early in...
Journal of Family Medicine and Primary Care : 2014 - 3(3)
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Assessment of the current knowledge and willingness to conduct medical research work of future healthcare providers: A cross-sectional study in Jeddah, Saudi Arabia
Ali S AlSayegh, Sara K Enayah, Wedyan N Khoja, Reem K Enayah, Naser S SendiJournal of Family Medicine and Primary Care 2020 9(3):1522-1527 Background and Objectives: Healthcare research work contributes significantly to the advancement and development of medical education. Numerous studies have demonstrated the efficiency and productivity of student participation in medical research work, which has a positive impact on the health system. In this study, we intended to examine medical students'...
Journal of Family Medicine and Primary Care : 2014 - 3(3)
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Rootless and prematurely erupted tooth: A case report
Pooja Singh, Manish JhaJournal of Family Medicine and Primary Care 2020 9(3):1741-1743 Tooth eruption is defined as the movement of a tooth from its site of development within the alveolar process to its functional position in the oral cavity. It is a complex process that can be influenced by a number of general factors like genetics, nutrition, preterm birth, socioeconomic factors, hormonal factors, various systemic diseases and some local factors. Timing of tooth eruption depends on the chronologic...
Journal of Family Medicine and Primary Care : 2014 - 3(3)
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Sociodemographic and clinical profile of geriatric patients with cervical cancer—An audit from a tertiary cancer center in India
Divyesh Kumar, Treshita Dey, Pooja Bansal, GY Srinivasa, Bhavana RaiJournal of Family Medicine and Primary Care 2020 9(3):1528-1532 Background and Aim: Cervical cancer is a major health problem among the female population worldwide. Its incidence among the elderly group of patients seems to be increasing. Sociodemographic along with clinical profile of patients is the first step in planning preventive and curative measures; we thus conducted a retrospective analysis of demographic and clinical...
Journal of Family Medicine and Primary Care : 2014 - 3(3)
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Dose-dependent L-dopa/carbidopa-induced hyponatremia presenting with hiccups
P Shihabudheen, PC Anver, NA Uvais, TP MohammedJournal of Family Medicine and Primary Care 2020 9(3):1749-1751 Levodopa (L-dopa) is the most effective antiparkinsonian agent and is well tolerated at all stages of the disease. However, both motor and nonmotor adverse events are reported with the use of L-dopa. Electrolyte imbalances such as hyponatremia and hiccups with L-dopa/carbidopa are very rare. For the first time, we are reporting a case of L-dopa/carbidopa-induced hyponatremia and hiccup...
Journal of Family Medicine and Primary Care : 2014 - 3(3)
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Prevalence of anemia and its association with dietary pattern among elderly population of urban slums in Kochi
Charutha Retnakumar, Maya Chacko, Devraj Ramakrishnan, Leyanna S George, Vijayakumar KrishnapillaiJournal of Family Medicine and Primary Care 2020 9(3):1533-1537 Background: Anemia is common among the elderly and it is the reason behind their poor survival. Anemia among the elderly is consistently disregarded, which can even incite cardiovascular complexities. The risk of physical decline for the elderly with iron insufficiency is twofold than that of others in the same age. The elderly populace...
Journal of Family Medicine and Primary Care : 2014 - 3(3)
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Florid cemento-osseous dysplasia associated with chronic suppurative osteomyelitis and multiple impacted tooth an incidental finding – A rare case report
Jayanta Saikia, Balaji Pachipulusu, Poornima GovindarajuJournal of Family Medicine and Primary Care 2020 9(3):1757-1761 Florid cemento-osseous dysplasia (FCOD) is a rare, benign, fibro osseous, and multifocal dysplastic lesion of the jaw that consists of cellular fibrous connective tissue with bone and cementum-like tissue. The word 'florid' was introduced to describe the wide spread, extensive manifestations of the disease in the jaws. FCOD is most commonly found in middle-aged, black women...
Journal of Family Medicine and Primary Care : 2014 - 3(3)
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High levels of non-communicable diseases risk factors among transgenders in Puducherry, South India
Manju Madhavan, Mahendra M Reddy, Palanivel Chinnakali, Sitanshu S Kar, Subitha LakshminarayananJournal of Family Medicine and Primary Care 2020 9(3):1538-1543 Context: Identification and documentation of risk factors for non-communicable diseases (NCDs) among an 'invisible community' like the transgenders (TGs) will throw light on the prevailing health status of one of the most marginalized populations in India, thereby paving way for initiating measures that would cater to their healthcare...
Journal of Family Medicine and Primary Care : 2014 - 3(3)
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Hashimoto's encephalopathy in association with retinitis pigmentosa – First reported case
Ritwik Ghosh, Subhankar Chatterjee, Devlina Roy, Souvik Dubey, Biman Kanti RayJournal of Family Medicine and Primary Care 2020 9(3):1765-1767 Hashimoto's Encephalopathy (HE), also known as steroid responsive encephalopathy associated with autoimmune thyroiditis (SREAT), is a proteiform disorder known for its wide spectrum of presentations from subtle neuropsychiatric manifestations, movement disorders, seizures, stroke-like episodes to coma. Here, we report a case of HE which initially masqueraded...
Journal of Family Medicine and Primary Care : 2014 - 3(3)
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Perception toward the family medicine services among the Physicians of Prince Sultan Military Medical City, Riyadh City, 2018: Cross-sectional study
Abrar A Alzahrani, Osamah K Alfentokh, Abdullah S Aloggaael, Ayman A. M Afifi, Mostafa A KofiJournal of Family Medicine and Primary Care 2020 9(3):1544-1549 Background: Family medicine is the medical specialty that continuously provides comprehensive type of health care for individuals and families. Although the family physician role is essential, this specialty faces underestimation by other physicians of other specialties, thus resulting in a considerable gap in their cooperation and coordination,...
Journal of Family Medicine and Primary Care : 2014 - 3(3)
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Uncontrolled diabetes: A difficult mother or a mother in difficulty?
Amir Babiker, Bothainah Alaqeel, Mohammed Alsaeed, Ghadeer Aljahdali, Abdulrahman Almunif, Sundeep SandhuJournal of Family Medicine and Primary Care 2020 9(3):1772-1774 Young children with diabetes (YCD) are a particularly vulnerable group because they are reliant on adult carers in their management. Diabetes treating teams (DTT) have a responsibility towards YCD targeting good glycemic control (GC) to improve quality of life and reduce risk of complications. It can be difficult, however, in...
Journal of Family Medicine and Primary Care : 2014 - 3(3)
17h
Metabolic changes in the patients on second-line highly active antiretroviral therapy (HAART): A prospective cohort study from north India
Durga S Meena, Madhukar Rai, Surya K Singh, Jaya Tapadar, Deepak KumarJournal of Family Medicine and Primary Care 2020 9(3):1550-1554 Introduction: In India, there is a genetic predisposition to insulin resistance and cardiovascular risk, the impact of ART (antiretroviral therapy) on lipid profile and blood sugar may be significant. The study of potential implications of highly active antiretroviral therapy (HAART)-associated metabolic syndrome is critical to prevent cardiovascular diseases in...
Journal of Family Medicine and Primary Care : 2014 - 3(3)
17h
Reinvigorating comprehensive primary healthcare is the way to resolve declining doctor-patient relationship
Jayanta BhattacharyaJournal of Family Medicine and Primary Care 2020 9(3):1778-1779
Journal of Family Medicine and Primary Care : 2014 - 3(3)
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Could intramuscular storage of dietary nitrate contribute to its ergogenic effect? A mini-review
Publication date: Available online 26 March 2020Source: Free Radical Biology and MedicineAuthor(s): Jean Nyakayiru, LucJ.C. van Loon, LexB. Verdijk
Free Radical Biology and Medicine
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4-Hydroxy-7-oxo-5-heptenoic acid (HOHA) lactone induces apoptosis in retinal pigment epithelial cells
Publication date: Available online 25 March 2020Source: Free Radical Biology and MedicineAuthor(s): Mikhail Linetsky, Junhong Guo, Emeka Udeigwe, Duoming Ma, Amanda S. Chamberlain, Annabelle O. Yu, Kseniya Solovyova, Elise Edgar, Robert G. Salomon
Free Radical Biology and Medicine
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Multiharmonic electron paramagnetic resonance imaging as an innovative approach for <em>in vivo</em> studies
Publication date: Available online 25 March 2020Source: Free Radical Biology and MedicineAuthor(s): Michal Gonet, Mikolaj Baranowski, Tomasz Czechowski, Małgorzata Kucinska, Adam Plewinski, Piotr Szczepanik, Stefan Jurga, Marek Murias
Free Radical Biology and Medicine
17h
Methionine sulfoxide reductase A (MsrA) modulates cells and protects against <em>Mycoplasma genitalium</em> induced cytotoxicity
Publication date: Available online 25 March 2020Source: Free Radical Biology and MedicineAuthor(s): Kishore Das, Omar Garnica, Javier Flores, Subramanian Dhandayuthapani
Free Radical Biology and Medicine
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Dimethyl sulfoxide, a potent oral radioprotective agent, confers radioprotection of hematopoietic stem and progenitor cells independent of apoptosis
Publication date: Available online 25 March 2020Source: Free Radical Biology and MedicineAuthor(s): Renjun Peng, Wenting Zhang, Zongchao Zuo, Yajun Shan, Xiaolan Liu, Yingying Tang, Zuyin Yu, Limei Wang, Yuwen Cong
Free Radical Biology and Medicine
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Evaluation of Spodick's Sign and Other Electrocardiographic Findings as Indicators of STEMI and Pericarditis
Publication date: Available online 25 March 2020Source: The Journal of Emergency MedicineAuthor(s): Michael D. Witting, Kami M. Hu, Aaron A. Westreich, Semhar Tewelde, Ali Farzad, Amal Mattu
ScienceDirect Publication: The Journal of Emergency Medicine
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Cross-sectional associations between angiotensin-converting enzyme inhibitor use and cancer diagnosis in US adults
Abstract The objective of the present study was to investigate the association between angiotensin-converting enzyme (ACE) inhibitor use and cancer incidence (overall, and breast, prostate, and colorectal cancers specifically) in a large representative sample of US adults. Cross-sectional data on cancer diagnosis, timing of cancer diagnosis, ACE inhibitor use, and other characteristics were extracted from 49 512 adults aged ≥ 20 years participating in the National Health and Nutrition...
Latest Results for Clinical and Experimental Medicine
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Proteomic Identification and Expression of Oral Apparatus Constituents in Cell Regeneration of Giant Ciliate <em>Stentor coeruleus</em> (Strain WHEL)
Publication date: Available online 26 March 2020Source: GeneAuthor(s): Wei Wei, Chuanqi Jiang, Wentao Yang, Wei Miao, Jie Xiong
Gene
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Hsa_circ_0061140 promotes endometrial carcinoma progression via regulating miR-149-5p/STAT3
Publication date: Available online 26 March 2020Source: GeneAuthor(s): Yun Liu, Yue Chang, Yixuan Cai
Gene
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Transcriptome profiling of buffalo endometrium reveals molecular signature distinct to early pregnancy
Publication date: Available online 25 March 2020Source: GeneAuthor(s): Manjit Panigrahi, Harshit Kumar, Vaishali Sah, Ankita Dillipkumar Verma, Bharat Bhushan, Subhashree Parida
Gene
17h
The multiple facets of the <em>SMC1A</em> gene
Publication date: Available online 25 March 2020Source: GeneAuthor(s): Antonio Musio
Gene
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Maintenance of meiotic crossover against reduced double-strand break formation in fission yeast lacking histone H2A.Z
Publication date: Available online 25 March 2020Source: GeneAuthor(s): Takatomi Yamada, Shintaro Yamada, Da-Qiao Ding, Yurika Fujita, Emi Takaya, Yasushi Hiraoka, Hiroshi Murakami, Kunihiro Ohta
Gene
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<em>Myrtus communis</em> subsp. <em>communis</em> improved cognitive functions in ovariectomized diabetic rats
Publication date: Available online 25 March 2020Source: GeneAuthor(s): Beril Kadıoğlu Yaman, Özge Çevik, Kübra Yalman, Büşra Ertaş, Ali Şen, Göksel Şener
Gene
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<em>TNFRSF11B</em> polymorphisms predict poor outcome after large artery atherosclerosis stroke
Publication date: Available online 25 March 2020Source: GeneAuthor(s): Mengmeng Wang, Mengmeng Gu, Zibao Li, Xuegan Lian, Huachao Shen, Zhengze Dai, Zhizhong Zhang, Xinfeng Liu
Gene
17h
Metformin enhances the sensitivity of colorectal cancer cells to cisplatin through ROS-mediated PI3K/Akt signaling pathway
Publication date: Available online 25 March 2020Source: GeneAuthor(s): Pei Zhang, Surong Zhao, Xingyue Lu, Zongfen Shi, Hao Liu, Bing Zhu
Gene
17h
Pneumologische Krankheitsbilder und Schlaf
Latest Results for Somnologie - Schlafforschung und Schlafmedizin
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Predict the particulate matter concentrations in 128 cities of China
Abstract To predict the concentrations of PM2.5 and PM10 in the 128 cities of China, the discrete gray prediction model with fractional order accumulation (DFGM(1,1)) was used to predict the annual average PM2.5 and PM10 concentrations from 2019 to 2023. The result is as following: the annual average PM2.5 concentrations of Xi’an, Xuzhou, Ordos, Jingmen, Meizhou, Huizhou, Panzhihua, Kunming, Jixi, and Yichun are increasing from 2019 to 2023. The annual average PM2.5 concentrations...
Latest Results for Air Quality, Atmosphere
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Antibodies, Vol. 9, Pages 8: Fast Confirmation of Antibody Identity by MALDI-TOF MS Fingerprints
Antibodies, Vol. 9, Pages 8: Fast Confirmation of Antibody Identity by MALDI-TOF MS Fingerprints Antibodies doi: 10.3390/antib9020008 Authors: Tscheuschner Schwaar Weller Thousands of antibodies for diagnostic and other analytical purposes are on the market. However, it is often difficult to identify duplicates, reagent changes, and to assign the correct original publications to an antibody. This slows down scientific progress and might even be a cause of irreproducible...
Antibodies
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In vivo anti-MUC1 + tumor activity and sequences of high-affinity anti-MUC1-SEA antibodies
Abstract Cleavage of the MUC1 glycoprotein yields two subunits, an extracellular alpha-subunit bound to a smaller transmembrane beta-subunit. Monoclonal antibodies (mAbs) directed against the MUC1 alpha–beta junction comprising the SEA domain, a stable cell-surface moiety, were generated. Sequencing of all seven anti-SEA domain mAbs showed that they clustered into four groups and sequences of all groups are presented here. mAb DMB5F3 with picomolar affinity for the MUC1 SEA target...
Latest Results for Cancer Immunology, Immunotherapy
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Correction to: Translational immune correlates of indirect antibody immunization in a randomized phase II study using scheduled combination therapy with carboplatin/paclitaxel plus oregovomab in ovarian cancer patients
The original version of this article unfortunately contained a mistake.
Latest Results for Cancer Immunology, Immunotherapy
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A phase I study of multi-HLA-binding peptides derived from heat shock protein 70/glypican-3 and a novel combination adjuvant of hLAG-3Ig and Poly-ICLC for patients with metastatic gastrointestinal cancers: YNP01 trial
Abstract Background This phase I study aimed to evaluate the safety, peptide-specific immune responses, and anti-tumor effects of a novel vaccination therapy comprising multi-HLA-binding heat shock protein (HSP) 70/glypican-3 (GPC3) peptides and a novel adjuvant combination of hLAG-3Ig and Poly-ICLC against metastatic gastrointestinal cancers. Methods ...
Latest Results for Cancer Immunology, Immunotherapy
18h

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